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The map label for this gene is plsC [H]

Identifier: 220917451

GI number: 220917451

Start: 2606131

End: 2606895

Strand: Direct

Name: plsC [H]

Synonym: A2cp1_2351

Alternate gene names: 220917451

Gene position: 2606131-2606895 (Clockwise)

Preceding gene: 220917448

Following gene: 220917452

Centisome position: 51.82

GC content: 72.16

Gene sequence:

>765_bases
ATGCTGGCGCGCGCCCGCGGCTTCGTCGTCCTCGTCTACTGCGCCATCTCGATGGCGTTCTTCTTCTTCGTGAGCCTGCC
GGTGATGCTCCTCACCGGCTCGGGCGACCTGCCGATCTGGTTCGCGCGGTTCGCCTGGTCGCCCTCGAGCCTGTGGCTCG
CCGGCTCCCGCGTGCACCTCGAGCCCATGCCGTCGCTGCCGGACGGGCCGCTCATCTTCGCGTCGAACCACGAGAGCGCG
CTCGACATCTGGGTGCTGTTCAAGGTCCTGCCGCGCAGCGTGCGGTTCATCGCCAAGGCCGAGCTGTTCCGCCTCCCGGT
GTTCGGCGCGTACATGCGGCTCGGCGGCCACGTGCCGGTGGACCGCAGCAACCACGTCCAGGCGGTCCAGTCGCTGCGGC
AGGCCGGCCAGGTGGTGCGCGCCGGGACGTCGCTCATCGTCTTCCCCGAGGGCACGCGCTCGATGGACTGCCGCGTCCAC
CCGTTCAAGAAGGGCCCGTTCGTGGTCGCGATGGAGGCGGGCGTGCCGGTGGTGCCGGTCGCCATCTCCGGCAGCGGGAA
GGTGACGCCCAAGCGGATCATCGCCATCTGGCCCGGCCCGATCCGCGTGGCGGTGGGCGAGCCGGTGAGCCCGGCCGACT
TCCCCGACAAGACCGCGCTGCTCACCGAGGTGCGCCGGCGGGTGATCGCGCTGCACCGGCGGATCGGCGGCGCGGGCGGC
GACGAGGCCTCGGCGGTCGCCACGGTGGGCATGGAGGGCGTGTGA

Upstream 100 bases:

>100_bases
TCACCGGAACAGTCTAGCGCCCCGGGCGCCGCCCGGGCGCGTGCTATATACGCCCCGCCCCGGGCCGCCCTGCCCGGCCG
GCCCGGTCCGAGAGGCACTC

Downstream 100 bases:

>100_bases
GACAGGGCGGACGCGGGCCTACCCGCTTGTCCCGCCGCGCCGGCGGGCGGTAGGCTCGGCCGCCATGAAGGAGACGCTCC
GTCCCGACGCGGTGGCCGCC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLARARGFVVLVYCAISMAFFFFVSLPVMLLTGSGDLPIWFARFAWSPSSLWLAGSRVHLEPMPSLPDGPLIFASNHESA
LDIWVLFKVLPRSVRFIAKAELFRLPVFGAYMRLGGHVPVDRSNHVQAVQSLRQAGQVVRAGTSLIVFPEGTRSMDCRVH
PFKKGPFVVAMEAGVPVVPVAISGSGKVTPKRIIAIWPGPIRVAVGEPVSPADFPDKTALLTEVRRRVIALHRRIGGAGG
DEASAVATVGMEGV

Sequences:

>Translated_254_residues
MLARARGFVVLVYCAISMAFFFFVSLPVMLLTGSGDLPIWFARFAWSPSSLWLAGSRVHLEPMPSLPDGPLIFASNHESA
LDIWVLFKVLPRSVRFIAKAELFRLPVFGAYMRLGGHVPVDRSNHVQAVQSLRQAGQVVRAGTSLIVFPEGTRSMDCRVH
PFKKGPFVVAMEAGVPVVPVAISGSGKVTPKRIIAIWPGPIRVAVGEPVSPADFPDKTALLTEVRRRVIALHRRIGGAGG
DEASAVATVGMEGV
>Mature_254_residues
MLARARGFVVLVYCAISMAFFFFVSLPVMLLTGSGDLPIWFARFAWSPSSLWLAGSRVHLEPMPSLPDGPLIFASNHESA
LDIWVLFKVLPRSVRFIAKAELFRLPVFGAYMRLGGHVPVDRSNHVQAVQSLRQAGQVVRAGTSLIVFPEGTRSMDCRVH
PFKKGPFVVAMEAGVPVVPVAISGSGKVTPKRIIAIWPGPIRVAVGEPVSPADFPDKTALLTEVRRRVIALHRRIGGAGG
DEASAVATVGMEGV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=244, Percent_Identity=32.3770491803279, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI5453718, Length=184, Percent_Identity=33.1521739130435, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI15100175, Length=184, Percent_Identity=33.1521739130435, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1789395, Length=135, Percent_Identity=30.3703703703704, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=174, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568319, Length=196, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=234, Percent_Identity=31.1965811965812, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641614, Length=250, Percent_Identity=27.2, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641612, Length=250, Percent_Identity=27.2, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281364648, Length=111, Percent_Identity=36.9369369369369, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582856, Length=111, Percent_Identity=36.9369369369369, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582854, Length=111, Percent_Identity=36.9369369369369, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27419; Mature: 27419

Theoretical pI: Translated: 11.06; Mature: 11.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARARGFVVLVYCAISMAFFFFVSLPVMLLTGSGDLPIWFARFAWSPSSLWLAGSRVHL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECCCCCEEEECCEEEE
EPMPSLPDGPLIFASNHESALDIWVLFKVLPRSVRFIAKAELFRLPVFGAYMRLGGHVPV
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
DRSNHVQAVQSLRQAGQVVRAGTSLIVFPEGTRSMDCRVHPFKKGPFVVAMEAGVPVVPV
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCCEEEEEECCCCEEEE
AISGSGKVTPKRIIAIWPGPIRVAVGEPVSPADFPDKTALLTEVRRRVIALHRRIGGAGG
EECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DEASAVATVGMEGV
CCCCEEEECCCCCC
>Mature Secondary Structure
MLARARGFVVLVYCAISMAFFFFVSLPVMLLTGSGDLPIWFARFAWSPSSLWLAGSRVHL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEECCCCCEEEECCEEEE
EPMPSLPDGPLIFASNHESALDIWVLFKVLPRSVRFIAKAELFRLPVFGAYMRLGGHVPV
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
DRSNHVQAVQSLRQAGQVVRAGTSLIVFPEGTRSMDCRVHPFKKGPFVVAMEAGVPVVPV
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCCEEEEEECCCCEEEE
AISGSGKVTPKRIIAIWPGPIRVAVGEPVSPADFPDKTALLTEVRRRVIALHRRIGGAGG
EECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DEASAVATVGMEGV
CCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]