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The map label for this gene is acdA [H]

Identifier: 220917382

GI number: 220917382

Start: 2533266

End: 2534435

Strand: Direct

Name: acdA [H]

Synonym: A2cp1_2282

Alternate gene names: 220917382

Gene position: 2533266-2534435 (Clockwise)

Preceding gene: 220917381

Following gene: 220917384

Centisome position: 50.37

GC content: 76.15

Gene sequence:

>1170_bases
ATGGACTTCGAGCTCGACGACACCCAGCGCGCGATCCAGGACACGGCGCGCGCCTTCGCCCGCGAGGAGGTCGCGCCGGC
CGCGGCCGAGAACGACCGGCTGCGGCGCTTCCCGGCGGACCTGATCCGCGGCCTGGGGGAGCTGGGACTGCTGGCGGTGA
ACGTCCCGGCGGCGTACGGCGGCTCGGAGGCCGGCGCGGTGGCGTACGCGCTCGCGATCATGGAGATCGCGGCGGCCGAC
TGCGCCACCGCGGTGACCATGGCCGTCACCAACATGGTGGGCGAGCTCATCGCGCGGTTCGGCACCGAGGCGCAGAAGCA
GCGCCACCTGCCGCGGCTCGCCGCCGCCGAGGTGCTGGCCGGCGCGTTCGCGCTCTCCGAGCCGCAGGCCGGCAGCGACG
CGGGCGCCATGCGCACGCGGGCGGTCCGCCGGGGCGATGGCTGGGTGATCGACGGCGCCAAGCAGTGGATCACGAGCGGC
GACGTGGCCGGGGTGCTGGTGGTCTGGGCGCGCACCGGGCCGGCGGAGGCGGGCGGGGGCGGCGGGGTGACCGCGTTCCT
GGTCGAGCAGGGCACCCCCGGGCTGCTGGTGGGGCGGCACGAGGACAAGCTCGGGATCCGCGCCAGCTCCACCGTGGCCC
TCTCGTTCGACGGGTGCGAGGTACCGGACTCGGCGCGCCTCGGCGAGGTGGGCCAGGGGCTGCGGGTGGCGTTCGCGGCG
CTGGACGGCGGCCGCGTCGGGATCGCCTCGCAGGCGACCGGCACCATCCGTGCCGCCCTCGACGCGAGCGTCCGCTACGC
GCGGGACCGGCAGGCGTTCGGAGTCCCCATCGCCGAGCACCAGGCGGTCGCGTTCATGCTCGCGGACATGGCGGTGGAGC
ACGACACGGCGCGGCTGCTGGCGCTCCGCGCGGCGGCGCTCAAGGAGGCCGGGCGGCCGTTCACGCGCGAGGCGTCGATG
GCGAAGCTGTGGGCCTCGGAGGCCGCGCAGCGGGCGGTGGGCCGCGCGGTGCAGATCCACGGCGGGGTCGGCTACACCGA
GGACTTCCCGGTGGCGCGCTACTTCCGCGACGCGCGGGTGCAGACCATCTACGAGGGCACGAGCGAGATCCAGCGCCTCG
TGATCGCGCGGGAGCTCCTGAAGGACGGCGGGGCGCCGGCGCGCGGTTAG

Upstream 100 bases:

>100_bases
CGGTGCTGAAGGGCTAGCCGCCGGCACCTCGACCGAGCGCTCCACCGGCGACCCCGCCCAGGGCGGCCCCGCGCCGGGCG
GAGCCACACCCGGATCCTGC

Downstream 100 bases:

>100_bases
GCGCGCCGCGCCGCGGGCGGTCAGGCGGTGCGCGCGGTGCCGTCGTCGTCGGTCTGGATGAGGTGCCCGGTCCGCTCGCG
CTTCACCCGCAGGTACTCGA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDFELDDTQRAIQDTARAFAREEVAPAAAENDRLRRFPADLIRGLGELGLLAVNVPAAYGGSEAGAVAYALAIMEIAAAD
CATAVTMAVTNMVGELIARFGTEAQKQRHLPRLAAAEVLAGAFALSEPQAGSDAGAMRTRAVRRGDGWVIDGAKQWITSG
DVAGVLVVWARTGPAEAGGGGGVTAFLVEQGTPGLLVGRHEDKLGIRASSTVALSFDGCEVPDSARLGEVGQGLRVAFAA
LDGGRVGIASQATGTIRAALDASVRYARDRQAFGVPIAEHQAVAFMLADMAVEHDTARLLALRAAALKEAGRPFTREASM
AKLWASEAAQRAVGRAVQIHGGVGYTEDFPVARYFRDARVQTIYEGTSEIQRLVIARELLKDGGAPARG

Sequences:

>Translated_389_residues
MDFELDDTQRAIQDTARAFAREEVAPAAAENDRLRRFPADLIRGLGELGLLAVNVPAAYGGSEAGAVAYALAIMEIAAAD
CATAVTMAVTNMVGELIARFGTEAQKQRHLPRLAAAEVLAGAFALSEPQAGSDAGAMRTRAVRRGDGWVIDGAKQWITSG
DVAGVLVVWARTGPAEAGGGGGVTAFLVEQGTPGLLVGRHEDKLGIRASSTVALSFDGCEVPDSARLGEVGQGLRVAFAA
LDGGRVGIASQATGTIRAALDASVRYARDRQAFGVPIAEHQAVAFMLADMAVEHDTARLLALRAAALKEAGRPFTREASM
AKLWASEAAQRAVGRAVQIHGGVGYTEDFPVARYFRDARVQTIYEGTSEIQRLVIARELLKDGGAPARG
>Mature_389_residues
MDFELDDTQRAIQDTARAFAREEVAPAAAENDRLRRFPADLIRGLGELGLLAVNVPAAYGGSEAGAVAYALAIMEIAAAD
CATAVTMAVTNMVGELIARFGTEAQKQRHLPRLAAAEVLAGAFALSEPQAGSDAGAMRTRAVRRGDGWVIDGAKQWITSG
DVAGVLVVWARTGPAEAGGGGGVTAFLVEQGTPGLLVGRHEDKLGIRASSTVALSFDGCEVPDSARLGEVGQGLRVAFAA
LDGGRVGIASQATGTIRAALDASVRYARDRQAFGVPIAEHQAVAFMLADMAVEHDTARLLALRAAALKEAGRPFTREASM
AKLWASEAAQRAVGRAVQIHGGVGYTEDFPVARYFRDARVQTIYEGTSEIQRLVIARELLKDGGAPARG

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=381, Percent_Identity=47.7690288713911, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=40.9574468085106, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI4557231, Length=382, Percent_Identity=40.0523560209424, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI187960098, Length=382, Percent_Identity=40.0523560209424, Blast_Score=265, Evalue=8e-71,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=36.2204724409449, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=36.1477572559367, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=36.3372093023256, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI21361497, Length=388, Percent_Identity=35.8247422680412, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI4557235, Length=394, Percent_Identity=34.5177664974619, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI76496475, Length=394, Percent_Identity=34.5177664974619, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI4501857, Length=371, Percent_Identity=32.8840970350404, Blast_Score=208, Evalue=8e-54,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=32.1052631578947, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI7669494, Length=368, Percent_Identity=31.7934782608696, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI48976061, Length=335, Percent_Identity=30.1492537313433, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI211971008, Length=335, Percent_Identity=30.1492537313433, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38505218, Length=366, Percent_Identity=27.3224043715847, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=30.0518134715026, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=29.5811518324607, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87081702, Length=360, Percent_Identity=28.8888888888889, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082384, Length=274, Percent_Identity=28.8321167883212, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=40, Blast_Score=281, Evalue=6e-76,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=39.0374331550802, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=38.1201044386423, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17569725, Length=383, Percent_Identity=38.9033942558747, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=37.2703412073491, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17538396, Length=387, Percent_Identity=37.4677002583979, Blast_Score=247, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=34.3085106382979, Blast_Score=237, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI71990804, Length=296, Percent_Identity=41.2162162162162, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=31.0344827586207, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=33.4277620396601, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=31.8421052631579, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=38.4615384615385, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17505929, Length=382, Percent_Identity=31.6753926701571, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=32.3529411764706, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=308, Percent_Identity=32.1428571428571, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=31.9502074688797, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17531913, Length=177, Percent_Identity=32.7683615819209, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=335, Percent_Identity=26.2686567164179, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=273, Percent_Identity=30.03663003663, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=273, Percent_Identity=30.03663003663, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356377, Length=380, Percent_Identity=46.0526315789474, Blast_Score=315, Evalue=3e-86,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=45, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24666513, Length=382, Percent_Identity=39.5287958115183, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=38.9473684210526, Blast_Score=267, Evalue=7e-72,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=34.4736842105263, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281363737, Length=356, Percent_Identity=34.2696629213483, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI19920834, Length=386, Percent_Identity=31.0880829015544, Blast_Score=164, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40706; Mature: 40706

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFELDDTQRAIQDTARAFAREEVAPAAAENDRLRRFPADLIRGLGELGLLAVNVPAAYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHCEEEEECCCCCC
GSEAGAVAYALAIMEIAAADCATAVTMAVTNMVGELIARFGTEAQKQRHLPRLAAAEVLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHH
GAFALSEPQAGSDAGAMRTRAVRRGDGWVIDGAKQWITSGDVAGVLVVWARTGPAEAGGG
HHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHCCCCCCEEEEEEECCCCCCCCCC
GGVTAFLVEQGTPGLLVGRHEDKLGIRASSTVALSFDGCEVPDSARLGEVGQGLRVAFAA
CCEEEEEEECCCCCEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCHHCCCCEEEEEE
LDGGRVGIASQATGTIRAALDASVRYARDRQAFGVPIAEHQAVAFMLADMAVEHDTARLL
ECCCCEEECCCCCCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALRAAALKEAGRPFTREASMAKLWASEAAQRAVGRAVQIHGGVGYTEDFPVARYFRDARV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHH
QTIYEGTSEIQRLVIARELLKDGGAPARG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFELDDTQRAIQDTARAFAREEVAPAAAENDRLRRFPADLIRGLGELGLLAVNVPAAYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHCEEEEECCCCCC
GSEAGAVAYALAIMEIAAADCATAVTMAVTNMVGELIARFGTEAQKQRHLPRLAAAEVLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHH
GAFALSEPQAGSDAGAMRTRAVRRGDGWVIDGAKQWITSGDVAGVLVVWARTGPAEAGGG
HHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHCCCCCCEEEEEEECCCCCCCCCC
GGVTAFLVEQGTPGLLVGRHEDKLGIRASSTVALSFDGCEVPDSARLGEVGQGLRVAFAA
CCEEEEEEECCCCCEEEECCCCCCCEEECCEEEEEECCCCCCCCCCCCHHCCCCEEEEEE
LDGGRVGIASQATGTIRAALDASVRYARDRQAFGVPIAEHQAVAFMLADMAVEHDTARLL
ECCCCEEECCCCCCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALRAAALKEAGRPFTREASMAKLWASEAAQRAVGRAVQIHGGVGYTEDFPVARYFRDARV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHH
QTIYEGTSEIQRLVIARELLKDGGAPARG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]