Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 220917360

GI number: 220917360

Start: 2509614

End: 2510606

Strand: Direct

Name: trpS [H]

Synonym: A2cp1_2260

Alternate gene names: 220917360

Gene position: 2509614-2510606 (Clockwise)

Preceding gene: 220917359

Following gene: 220917361

Centisome position: 49.9

GC content: 67.57

Gene sequence:

>993_bases
ATGTCCTCGAAGCGCCCCATCATCGTCAGCGGCATGCGGCCCACCGGCCGCCTCCACCTCGGCCACCTGCACGGCGCGCT
CGCGAACTGGGTCAAGCTCCAGGACGACAACGAGTGCTTCTACTTCAGCGCGGACTGGCACGCGCTCACCACGAACTACC
ACGACACCTCGGTCATCAAGCAGGCCGAGCGCGAGATGTTCGTGGACTTCATCGCCGCGGGCATCGACCCCTCGCGGTCG
ACGCTGTTCATCCAGAGCCGGGTGAAGCAGCACGCCGAGCTGAACCTGCTGCTCGGCATGATCACGCCGCTCGGGTGGCT
GGAGCGCTCGCCGACGTACAAGGAGCAGCGCGAGAACATCACCGACCGCGACCTCGCCCTGTACGGCTTCCTCGGCTACC
CGGTGCTGATGACCGCGGACATCATCCTGTACAAGGCCACCCGCGTGCCGGTGGGCGTCGACCAGGTGCCGCACCTGGAG
CTGTCGCGCGAGATCGTCCGCAAGTTCAACTTCCACTACGGCGAGGTGTTCCCCGAGCCGCAGCCGCTGCTCACCGCCGC
TCCCAAGATCCTGGGCACCGACGGCCGGAAGATGTCGAAGAGCTACGGCAACACCATCGACCTGGGCGAGAGCGCCGAGT
CCACGCAGAAGAAGATCATGGGCATGGTCACCGACCCGGCCCGCAAGCGGCGGCAGGACCCGGGCAACCCGGACGTCTGC
GGCGTGTTCTACCTGCACAAGGTGACGAGCGACGCCGAGACCGTCGCCTGGGTGGACCAGAACTGCCGCACCGCCGGGAT
CGGCTGCGTGGACTGCAAGAAGAAGCTGCTCGAGCGGCTCCTGCCGCAGCAGGAGGAGATGCGCGCGCGGCGCGAGGCGC
TGCTCGCGAAGCCGAAGGACCTCGACGACATCGTGCAGCTCGGGAACGAGAAGGCGCGCGCCGCGGCGGAGGCCAACATG
GTCCAGGTCCGCGCCGCGATGAAGCTCGAGTAG

Upstream 100 bases:

>100_bases
TCTTCGCCGGCCGCATCATCTCGGGCCCGTCGAGCTTCGTGGTCGGCCTGCTCGCCCAGCTCGCCGGCGCCATCACCGCC
TGACCCGCACCCGGAGATCC

Downstream 100 bases:

>100_bases
GACCCACCACGGGGGGCGGTCCGCCGGGATGGCCAGGAACAGCGACACGGACGCCGGGCTCGGCGCGGACTCGCCGCGCG
CCGACGACGCCGACGCGCGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSSKRPIIVSGMRPTGRLHLGHLHGALANWVKLQDDNECFYFSADWHALTTNYHDTSVIKQAEREMFVDFIAAGIDPSRS
TLFIQSRVKQHAELNLLLGMITPLGWLERSPTYKEQRENITDRDLALYGFLGYPVLMTADIILYKATRVPVGVDQVPHLE
LSREIVRKFNFHYGEVFPEPQPLLTAAPKILGTDGRKMSKSYGNTIDLGESAESTQKKIMGMVTDPARKRRQDPGNPDVC
GVFYLHKVTSDAETVAWVDQNCRTAGIGCVDCKKKLLERLLPQQEEMRARREALLAKPKDLDDIVQLGNEKARAAAEANM
VQVRAAMKLE

Sequences:

>Translated_330_residues
MSSKRPIIVSGMRPTGRLHLGHLHGALANWVKLQDDNECFYFSADWHALTTNYHDTSVIKQAEREMFVDFIAAGIDPSRS
TLFIQSRVKQHAELNLLLGMITPLGWLERSPTYKEQRENITDRDLALYGFLGYPVLMTADIILYKATRVPVGVDQVPHLE
LSREIVRKFNFHYGEVFPEPQPLLTAAPKILGTDGRKMSKSYGNTIDLGESAESTQKKIMGMVTDPARKRRQDPGNPDVC
GVFYLHKVTSDAETVAWVDQNCRTAGIGCVDCKKKLLERLLPQQEEMRARREALLAKPKDLDDIVQLGNEKARAAAEANM
VQVRAAMKLE
>Mature_329_residues
SSKRPIIVSGMRPTGRLHLGHLHGALANWVKLQDDNECFYFSADWHALTTNYHDTSVIKQAEREMFVDFIAAGIDPSRST
LFIQSRVKQHAELNLLLGMITPLGWLERSPTYKEQRENITDRDLALYGFLGYPVLMTADIILYKATRVPVGVDQVPHLEL
SREIVRKFNFHYGEVFPEPQPLLTAAPKILGTDGRKMSKSYGNTIDLGESAESTQKKIMGMVTDPARKRRQDPGNPDVCG
VFYLHKVTSDAETVAWVDQNCRTAGIGCVDCKKKLLERLLPQQEEMRARREALLAKPKDLDDIVQLGNEKARAAAEANMV
QVRAAMKLE

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=322, Percent_Identity=33.5403726708075, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI41352700, Length=185, Percent_Identity=40.5405405405405, Blast_Score=137, Evalue=9e-33,
Organism=Escherichia coli, GI1789786, Length=227, Percent_Identity=40.9691629955947, Blast_Score=167, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=32.2388059701493, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=31.9526627218935, Blast_Score=138, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=31.6091954022989, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666151, Length=331, Percent_Identity=32.02416918429, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37162; Mature: 37031

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKRPIIVSGMRPTGRLHLGHLHGALANWVKLQDDNECFYFSADWHALTTNYHDTSVIK
CCCCCCEEEECCCCCCCEEEHHHHHHHHHHEEECCCCCEEEEECCCEEEECCCCHHHHHH
QAEREMFVDFIAAGIDPSRSTLFIQSRVKQHAELNLLLGMITPLGWLERSPTYKEQRENI
HHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHCCC
TDRDLALYGFLGYPVLMTADIILYKATRVPVGVDQVPHLELSREIVRKFNFHYGEVFPEP
CCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
QPLLTAAPKILGTDGRKMSKSYGNTIDLGESAESTQKKIMGMVTDPARKRRQDPGNPDVC
CCHHHHCCHHHCCCCHHHHHHCCCEECCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCEE
GVFYLHKVTSDAETVAWVDQNCRTAGIGCVDCKKKLLERLLPQQEEMRARREALLAKPKD
HHHEEHHHCCCCHHEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LDDIVQLGNEKARAAAEANMVQVRAAMKLE
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSKRPIIVSGMRPTGRLHLGHLHGALANWVKLQDDNECFYFSADWHALTTNYHDTSVIK
CCCCCEEEECCCCCCCEEEHHHHHHHHHHEEECCCCCEEEEECCCEEEECCCCHHHHHH
QAEREMFVDFIAAGIDPSRSTLFIQSRVKQHAELNLLLGMITPLGWLERSPTYKEQRENI
HHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHCCC
TDRDLALYGFLGYPVLMTADIILYKATRVPVGVDQVPHLELSREIVRKFNFHYGEVFPEP
CCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
QPLLTAAPKILGTDGRKMSKSYGNTIDLGESAESTQKKIMGMVTDPARKRRQDPGNPDVC
CCHHHHCCHHHCCCCHHHHHHCCCEECCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCEE
GVFYLHKVTSDAETVAWVDQNCRTAGIGCVDCKKKLLERLLPQQEEMRARREALLAKPKD
HHHEEHHHCCCCHHEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
LDDIVQLGNEKARAAAEANMVQVRAAMKLE
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]