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The map label for this gene is yfdZ [H]

Identifier: 220917313

GI number: 220917313

Start: 2456286

End: 2457491

Strand: Direct

Name: yfdZ [H]

Synonym: A2cp1_2213

Alternate gene names: 220917313

Gene position: 2456286-2457491 (Clockwise)

Preceding gene: 220917312

Following gene: 220917314

Centisome position: 48.84

GC content: 72.64

Gene sequence:

>1206_bases
ATGAAGACCTTCAACGACCCCGAGGCCTTTGCGCGCGTCAAGCGCCTGCCGCCGTACGTCTTCACCGTCACCGATCGCCT
GCGCGACGAGGCCATCGCGCGCGGGGTGGACGTGGTGGACTTCTCCATGGGCAACCCGGACGGCGCCACGCCGGACCGGA
TCGTGGAGCGGCTGCGCAGCGCCGTGGGGGACCCGAAGCTGCACCGGTACCTGAACCCGCGCGGCCAGCCGGAGCTGCGC
GCGGCGGTGTCGCGCTGGTGGAAGCGGCGCCAGGGCGTCGAGGTCGATCCCGAGCGCGAGGTGCTCGTCACCATCGGCTC
GAAGGAGGGCATCGGGCACGCCCTCATCGCCATGCTCGCCGAGGGCGACACGGTCCTCGCGCCCGCGCCGACCTATCCCA
TCCACGCGTTCGGCGCGGTGCTGGCGGGCGCCGAGTCCTTGCCGGTGGCGGTCGGCCCGGGCGTGGACTTCTTCGAGTCG
CTGGTGGCCGCGGCGGAGCGCGCCGAGAAGCGGCCGAAGGGCCTGGTGGTGAACTTCCCCGCGAACCCGACCGCGGCGGT
GGCCACCCAGGAGCTGTTCGAGAAGATCGTCCGGTTCGCCGAGGCGCGGGACATGTTCATCGTGTCCGACCTGGCCTACT
GCGACATCGTCTTCGACGGCCCGAAGGCGCCGTCGATGCTGGCCGTGCCGGGCGCGCGCGACCGCACCCTCGAGTTCATG
TCGCTGTCGAAGAGCTACAACATGCCGGGCTGGCGCGTGGGCTTCTGCGCGGGCAACCCGGCGCTGGTGGCCGCGGCGGC
GCGGGTGAAGAGCTACCTCGACTACGGCCTGTTCGGCGCCGTGCAGGCCGCCGCGATCACCGCGCTCGACGAGTGCGACG
ACGAGGTGGTGAAGATCCGCGAGAAGTACCGGGTCCGCCGCGACGCGCTCGTCCGCCACTTCGGCGCGGCCGGGTGGCAG
GTGCCGGCGCCGGCCGCCTCGATGTTCGCGTGGGCGCCCATCCCCGAGCCGTTCCGCCAGCTCGGCTCGCTGGAGTTCTG
CAAGCGGCTCATCGACGAGGCCGGCGTCGCGGTCGCCCCGGGCATCGGCTTCGGGCCGACCGGCGAGGGCAGCGTCCGCA
TCGCGCTCATCGTGGACGAGCCGCGCGTGCAGCTCGCCGCCGAGCGGATCGAGAAGTTCCTCAAGAAGGGCCCGGGCGGG
CGGTAG

Upstream 100 bases:

>100_bases
CCGGGCCATGTCCCGCTTGCGGGGCACGCGCGCCCGTCACGGCGGGGTAGCTCGGCGCTTGCCATTCGGCGCGCGTCCCG
GCAAATTGGCGGGTCCCGCC

Downstream 100 bases:

>100_bases
CGATGGCCGCGCCCGCGTTCTCGTCCTGGTTCCGCTGCGCGGACGGTTGCGACTTCCGCGCCGAGCTCACCGAGGTGGTC
TACGAGTGCCCGCGCTGCGG

Product: class I and II aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKTFNDPEAFARVKRLPPYVFTVTDRLRDEAIARGVDVVDFSMGNPDGATPDRIVERLRSAVGDPKLHRYLNPRGQPELR
AAVSRWWKRRQGVEVDPEREVLVTIGSKEGIGHALIAMLAEGDTVLAPAPTYPIHAFGAVLAGAESLPVAVGPGVDFFES
LVAAAERAEKRPKGLVVNFPANPTAAVATQELFEKIVRFAEARDMFIVSDLAYCDIVFDGPKAPSMLAVPGARDRTLEFM
SLSKSYNMPGWRVGFCAGNPALVAAAARVKSYLDYGLFGAVQAAAITALDECDDEVVKIREKYRVRRDALVRHFGAAGWQ
VPAPAASMFAWAPIPEPFRQLGSLEFCKRLIDEAGVAVAPGIGFGPTGEGSVRIALIVDEPRVQLAAERIEKFLKKGPGG
R

Sequences:

>Translated_401_residues
MKTFNDPEAFARVKRLPPYVFTVTDRLRDEAIARGVDVVDFSMGNPDGATPDRIVERLRSAVGDPKLHRYLNPRGQPELR
AAVSRWWKRRQGVEVDPEREVLVTIGSKEGIGHALIAMLAEGDTVLAPAPTYPIHAFGAVLAGAESLPVAVGPGVDFFES
LVAAAERAEKRPKGLVVNFPANPTAAVATQELFEKIVRFAEARDMFIVSDLAYCDIVFDGPKAPSMLAVPGARDRTLEFM
SLSKSYNMPGWRVGFCAGNPALVAAAARVKSYLDYGLFGAVQAAAITALDECDDEVVKIREKYRVRRDALVRHFGAAGWQ
VPAPAASMFAWAPIPEPFRQLGSLEFCKRLIDEAGVAVAPGIGFGPTGEGSVRIALIVDEPRVQLAAERIEKFLKKGPGG
R
>Mature_401_residues
MKTFNDPEAFARVKRLPPYVFTVTDRLRDEAIARGVDVVDFSMGNPDGATPDRIVERLRSAVGDPKLHRYLNPRGQPELR
AAVSRWWKRRQGVEVDPEREVLVTIGSKEGIGHALIAMLAEGDTVLAPAPTYPIHAFGAVLAGAESLPVAVGPGVDFFES
LVAAAERAEKRPKGLVVNFPANPTAAVATQELFEKIVRFAEARDMFIVSDLAYCDIVFDGPKAPSMLAVPGARDRTLEFM
SLSKSYNMPGWRVGFCAGNPALVAAAARVKSYLDYGLFGAVQAAAITALDECDDEVVKIREKYRVRRDALVRHFGAAGWQ
VPAPAASMFAWAPIPEPFRQLGSLEFCKRLIDEAGVAVAPGIGFGPTGEGSVRIALIVDEPRVQLAAERIEKFLKKGPGG
R

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=25.0632911392405, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=25.0632911392405, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI56713254, Length=308, Percent_Identity=24.025974025974, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI56713256, Length=308, Percent_Identity=24.025974025974, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI169881281, Length=251, Percent_Identity=22.7091633466135, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI4885351, Length=374, Percent_Identity=26.7379679144385, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=52.8497409326425, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=27.012987012987, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788627, Length=251, Percent_Identity=29.0836653386454, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=242, Percent_Identity=25.6198347107438, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=242, Percent_Identity=25.6198347107438, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=389, Percent_Identity=21.8508997429306, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=316, Percent_Identity=25, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320317, Length=354, Percent_Identity=24.8587570621469, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=398, Percent_Identity=22.8643216080402, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=338, Percent_Identity=23.9644970414201, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573069, Length=401, Percent_Identity=22.9426433915212, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646114, Length=401, Percent_Identity=22.9426433915212, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573067, Length=401, Percent_Identity=22.9426433915212, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573065, Length=401, Percent_Identity=22.9426433915212, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43479; Mature: 43479

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFNDPEAFARVKRLPPYVFTVTDRLRDEAIARGVDVVDFSMGNPDGATPDRIVERLRS
CCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
AVGDPKLHRYLNPRGQPELRAAVSRWWKRRQGVEVDPEREVLVTIGSKEGIGHALIAMLA
HHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
EGDTVLAPAPTYPIHAFGAVLAGAESLPVAVGPGVDFFESLVAAAERAEKRPKGLVVNFP
CCCEEECCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEECC
ANPTAAVATQELFEKIVRFAEARDMFIVSDLAYCDIVFDGPKAPSMLAVPGARDRTLEFM
CCCHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCEEECCCCCCHHHHHH
SLSKSYNMPGWRVGFCAGNPALVAAAARVKSYLDYGLFGAVQAAAITALDECDDEVVKIR
HHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EKYRVRRDALVRHFGAAGWQVPAPAASMFAWAPIPEPFRQLGSLEFCKRLIDEAGVAVAP
HHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCCCHHHHHCCCHHHHHHHHHHCCCEEEC
GIGFGPTGEGSVRIALIVDEPRVQLAAERIEKFLKKGPGGR
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKTFNDPEAFARVKRLPPYVFTVTDRLRDEAIARGVDVVDFSMGNPDGATPDRIVERLRS
CCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
AVGDPKLHRYLNPRGQPELRAAVSRWWKRRQGVEVDPEREVLVTIGSKEGIGHALIAMLA
HHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
EGDTVLAPAPTYPIHAFGAVLAGAESLPVAVGPGVDFFESLVAAAERAEKRPKGLVVNFP
CCCEEECCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEECC
ANPTAAVATQELFEKIVRFAEARDMFIVSDLAYCDIVFDGPKAPSMLAVPGARDRTLEFM
CCCHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCEEECCCCCCHHHHHH
SLSKSYNMPGWRVGFCAGNPALVAAAARVKSYLDYGLFGAVQAAAITALDECDDEVVKIR
HHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EKYRVRRDALVRHFGAAGWQVPAPAASMFAWAPIPEPFRQLGSLEFCKRLIDEAGVAVAP
HHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCCCHHHHHCCCHHHHHHHHHHCCCEEEC
GIGFGPTGEGSVRIALIVDEPRVQLAAERIEKFLKKGPGGR
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]