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The map label for this gene is coaD

Identifier: 220917305

GI number: 220917305

Start: 2445878

End: 2446372

Strand: Direct

Name: coaD

Synonym: A2cp1_2205

Alternate gene names: 220917305

Gene position: 2445878-2446372 (Clockwise)

Preceding gene: 220917304

Following gene: 220917306

Centisome position: 48.63

GC content: 67.27

Gene sequence:

>495_bases
ATGAACCGCGCCGCCATCTACCCTGGCTCGTTCGATCCGCTCACCAACGGGCACCTCGCGATCATCCAGCGCGGGCTGAA
CCTGTTCGACCGGCTCGTCGTGGCGGTCGCGAACAACCCGCAGAAGTCGCCGATGTTCACGGTCGACGAGCGCAAGGCGC
TCATCCGCGAGGCCGTGGGCAACGATCCGCGCGTCGAGGTGGACTCCTTCGACGGCCTGATGGTGGACTACGCCCGCACG
CGCGGTATCCCCAAGGTGCTGCGCGGGCTGCGGGCGGTCTCGGACTTCGAGTACGAGTTCCAGCTCGCGAACATGAACAA
GAAGCTGCTGCCGGAGTTCGAGTCGGTCTTCGTGATGACCGGCGAGGACTACTTCTTCGTCTCGGCGCGGCTGGTTCGCG
AGGTGGCGCAGTTCGGCGGCAACGTCGAGGGCCTGGTGCCGGCGAACGTGCTCGAGGCGCTCCAGCGCAAGCTGGGCCGC
CCGCCGCGAAGCTGA

Upstream 100 bases:

>100_bases
GTGGACCGGATCGGTCCACTCTCGCTGGCGGATCGGCGCACGTACGGCGGCACGGGAATCTCGATCTACCAGCGCGACTG
AGCGATACTGCGCACCCCAC

Downstream 100 bases:

>100_bases
TCCGCGGCGCCCGCCGCCCACGGGGGAAGCCCGCCGGCCGCGCAGCACGCCCCTGGCGGCGAGCACCCGTTCTGGTATTC
TCGGTTCCCTTTTTTTCACG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MNRAAIYPGSFDPLTNGHLAIIQRGLNLFDRLVVAVANNPQKSPMFTVDERKALIREAVGNDPRVEVDSFDGLMVDYART
RGIPKVLRGLRAVSDFEYEFQLANMNKKLLPEFESVFVMTGEDYFFVSARLVREVAQFGGNVEGLVPANVLEALQRKLGR
PPRS

Sequences:

>Translated_164_residues
MNRAAIYPGSFDPLTNGHLAIIQRGLNLFDRLVVAVANNPQKSPMFTVDERKALIREAVGNDPRVEVDSFDGLMVDYART
RGIPKVLRGLRAVSDFEYEFQLANMNKKLLPEFESVFVMTGEDYFFVSARLVREVAQFGGNVEGLVPANVLEALQRKLGR
PPRS
>Mature_164_residues
MNRAAIYPGSFDPLTNGHLAIIQRGLNLFDRLVVAVANNPQKSPMFTVDERKALIREAVGNDPRVEVDSFDGLMVDYART
RGIPKVLRGLRAVSDFEYEFQLANMNKKLLPEFESVFVMTGEDYFFVSARLVREVAQFGGNVEGLVPANVLEALQRKLGR
PPRS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=49.0566037735849, Blast_Score=173, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_ANAD2 (B8J9D7)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002492609.1
- ProteinModelPortal:   B8J9D7
- GeneID:   7297215
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_2205
- HOGENOM:   HBG288308
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18371; Mature: 18371

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAAIYPGSFDPLTNGHLAIIQRGLNLFDRLVVAVANNPQKSPMFTVDERKALIREAVG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHC
NDPRVEVDSFDGLMVDYARTRGIPKVLRGLRAVSDFEYEFQLANMNKKLLPEFESVFVMT
CCCCEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCEEEEEE
GEDYFFVSARLVREVAQFGGNVEGLVPANVLEALQRKLGRPPRS
CCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNRAAIYPGSFDPLTNGHLAIIQRGLNLFDRLVVAVANNPQKSPMFTVDERKALIREAVG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHC
NDPRVEVDSFDGLMVDYARTRGIPKVLRGLRAVSDFEYEFQLANMNKKLLPEFESVFVMT
CCCCEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCEEEEEE
GEDYFFVSARLVREVAQFGGNVEGLVPANVLEALQRKLGRPPRS
CCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA