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The map label for this gene is cysH [H]

Identifier: 220917300

GI number: 220917300

Start: 2441403

End: 2442122

Strand: Reverse

Name: cysH [H]

Synonym: A2cp1_2200

Alternate gene names: 220917300

Gene position: 2442122-2441403 (Counterclockwise)

Preceding gene: 220917301

Following gene: 220917299

Centisome position: 48.56

GC content: 78.33

Gene sequence:

>720_bases
GTGAGCGAGCCGATCGCGCAGGAGCTGGCGGCGCTGGCGGCGCGCCACGAGGGCGGCCAGCCGGAGGAGATCCTGGCCGC
CGCGGCGGAGCGGTTCCCCGGGCGCATCGCGCTCGCGTGCAGCTTCGGCGCCGAGGACTGCCTGCTGGTGGACGCGGTCG
GGCGCGCGCGGCTGCCCGTCGAGATCTTCACCATCGACACCGGGTTCCTGTTCGCGGAGACGTACGCGCTGTGGGGCCGC
CTCGAGGCGCGCCACGGGCTGCGGATCCGCGCGGTGAAGGGCGACGCGCCGGCGGTGGTGCCGGCCGGCGAGCCGCCGCC
CTGGGAGCGCGACCCGGACGCCTGCTGTGACGTGCGCAAGGTCCGGCCGCTGCGGGCGGCGCTCGCCGCGCTCGGCCCCT
CCGGCGGCTGGGTCACCGGCATCCGCCGCGACCAGACCCCGGACCGCGGCGGCGCGCGCGCCTTCGAGTGGGATCCGCGC
TTCGGCCTCGCGAAGGTGAACCCGCTCGTCGCCTGGACCTCCGACGACGTCTGGCGCCGCCTCCGCCGGCTCGGCGTGCC
CACCAACCCGCTGCACGAGCAGGGCTACCCGTCCATCGGCTGCGCCCCCTGCACCAGCCCGGTGCGGCCCGGCGAGGATC
CGCGCGCCGGGCGCTGGCGCGGGCGCGAGAAGACCGAGTGCGGGCTGCACCGGCTCGGGCCGGGCGGGGAGCGGCGATGA

Upstream 100 bases:

>100_bases
AGCCCGTCGCGCCCGACCGCTACGCCGACGCCCGCGCCACCGGCGCGTTCGTGGTGATCGACGAGGCGACCAACGACACG
GTGGGCGCGGGGATGATCCA

Downstream 100 bases:

>100_bases
CCGCGGTCGGCGCGGCGACGCTCCCGGGCCGGGCGCGCCGGGTGCTGCCCGGCTTCGGGCTCTCCACCGGGCTCACCGTC
GCCTGGCTCTCCGCGGTGGT

Product: phosphoadenylyl-sulfate reductase (thioredoxin)

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSEPIAQELAALAARHEGGQPEEILAAAAERFPGRIALACSFGAEDCLLVDAVGRARLPVEIFTIDTGFLFAETYALWGR
LEARHGLRIRAVKGDAPAVVPAGEPPPWERDPDACCDVRKVRPLRAALAALGPSGGWVTGIRRDQTPDRGGARAFEWDPR
FGLAKVNPLVAWTSDDVWRRLRRLGVPTNPLHEQGYPSIGCAPCTSPVRPGEDPRAGRWRGREKTECGLHRLGPGGERR

Sequences:

>Translated_239_residues
MSEPIAQELAALAARHEGGQPEEILAAAAERFPGRIALACSFGAEDCLLVDAVGRARLPVEIFTIDTGFLFAETYALWGR
LEARHGLRIRAVKGDAPAVVPAGEPPPWERDPDACCDVRKVRPLRAALAALGPSGGWVTGIRRDQTPDRGGARAFEWDPR
FGLAKVNPLVAWTSDDVWRRLRRLGVPTNPLHEQGYPSIGCAPCTSPVRPGEDPRAGRWRGREKTECGLHRLGPGGERR
>Mature_238_residues
SEPIAQELAALAARHEGGQPEEILAAAAERFPGRIALACSFGAEDCLLVDAVGRARLPVEIFTIDTGFLFAETYALWGRL
EARHGLRIRAVKGDAPAVVPAGEPPPWERDPDACCDVRKVRPLRAALAALGPSGGWVTGIRRDQTPDRGGARAFEWDPRF
GLAKVNPLVAWTSDDVWRRLRRLGVPTNPLHEQGYPSIGCAPCTSPVRPGEDPRAGRWRGREKTECGLHRLGPGGERR

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=226, Percent_Identity=29.2035398230088, Blast_Score=95, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6325425, Length=223, Percent_Identity=33.6322869955157, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 25990; Mature: 25859

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPIAQELAALAARHEGGQPEEILAAAAERFPGRIALACSFGAEDCLLVDAVGRARLPV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCE
EIFTIDTGFLFAETYALWGRLEARHGLRIRAVKGDAPAVVPAGEPPPWERDPDACCDVRK
EEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHH
VRPLRAALAALGPSGGWVTGIRRDQTPDRGGARAFEWDPRFGLAKVNPLVAWTSDDVWRR
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCEEECCCCCCCEECCEEEEECCHHHHHH
LRRLGVPTNPLHEQGYPSIGCAPCTSPVRPGEDPRAGRWRGREKTECGLHRLGPGGERR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEPIAQELAALAARHEGGQPEEILAAAAERFPGRIALACSFGAEDCLLVDAVGRARLPV
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCE
EIFTIDTGFLFAETYALWGRLEARHGLRIRAVKGDAPAVVPAGEPPPWERDPDACCDVRK
EEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHH
VRPLRAALAALGPSGGWVTGIRRDQTPDRGGARAFEWDPRFGLAKVNPLVAWTSDDVWRR
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCEEECCCCCCCEECCEEEEECCHHHHHH
LRRLGVPTNPLHEQGYPSIGCAPCTSPVRPGEDPRAGRWRGREKTECGLHRLGPGGERR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA