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The map label for this gene is cysW [H]

Identifier: 220917298

GI number: 220917298

Start: 2439704

End: 2440555

Strand: Reverse

Name: cysW [H]

Synonym: A2cp1_2198

Alternate gene names: 220917298

Gene position: 2440555-2439704 (Counterclockwise)

Preceding gene: 220917299

Following gene: 220917297

Centisome position: 48.53

GC content: 72.89

Gene sequence:

>852_bases
ATGAGCGCGCGCGTCGCCAACCAGGATCCGGCCGCGGTGCGGTGGGCGCTCACCGGCCTCGCGCTCGCGTTCCTGGCGGC
GTTCGTGCTGGTCCCGGCCGCGGCCGTGCTGTGGGAGGCGGTGCGCGGCGGCGCCCAGGTCTGGTGGGCGGCCGTGACCG
ACCCCGACGCGCGCGCCGCCATCCGGCTGACGCTGCTCGTGGCCGCCTGGTCGGTGCCGCTCAACACCGCGTTCGGGATC
GCCGCCGCGTGGTCGCTGACCCGCTTCCGGTTCCGGGGCAAGAGCCTGCTCGTCTCGCTGGTGGACCTGCCGTTCGGCGT
CTCGCCGGTCATCTCCGGGATGGTGACGGTGCTGCTGTTCGGGGCGCAGGGCTGGCTCGGCCCGTGGCTCGACGCGCACG
GGCTGAAGGTGGTGTTCGCGGTCCCGGGCATCGTCCTCGCGACGGTGTTCGTGACGTTCCCGTTCGTCGCACGCGAGCTC
ATCCCGTTCATGGAGGCGCAGGGCGTCGAGGAGGAGGAGGCCGCGCTCGTGCTGGGCGCGAGCGGCTGGCAGATCCTCTC
CCGCGTCACGCTGCCCAACGTGAAGTGGAGCCTGCTGTACGGCGTCGTCCTGTGCAACGCCCGCGCGATGGGCGAGTTCG
GGGCCGTCTCGGTGGTCTCCGGCCACGTGCGCGGGGTGACGAACACCATCCCGCTCCACGTCGAGATCCTCTACGACGAG
TACGCGTTCCGCGCGTCCTTCGCGGTCGCCTCCCTCCTGTTCCTCCTCGCGCTGGTCACGCTCGTCGCCAAGAAGGCGCT
CGAGTGGAGGCAGCGGTCGGCGCGGGCGGCGGCCCGCCGGAGCCACGCATGA

Upstream 100 bases:

>100_bases
GCGCCTCGGCGATCGCGTGCGTGCTGCTGGGCACCTCGTTCGCGCTGCTCCTCGGGATCAACCGGCTGCAGGCCTGGACC
CGCGTGCGCACGGGGACGGC

Downstream 100 bases:

>100_bases
GCATCGAGATCCGCAACCTGTCCAAGTCGTTCGACGCCCACCCGGTCCTGCGCGACGTCACGCTCGACATCCCCGAGGGC
GAGCTGGTGGCGCTGCTCGG

Product: sulfate ABC transporter, inner membrane subunit CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSARVANQDPAAVRWALTGLALAFLAAFVLVPAAAVLWEAVRGGAQVWWAAVTDPDARAAIRLTLLVAAWSVPLNTAFGI
AAAWSLTRFRFRGKSLLVSLVDLPFGVSPVISGMVTVLLFGAQGWLGPWLDAHGLKVVFAVPGIVLATVFVTFPFVAREL
IPFMEAQGVEEEEAALVLGASGWQILSRVTLPNVKWSLLYGVVLCNARAMGEFGAVSVVSGHVRGVTNTIPLHVEILYDE
YAFRASFAVASLLFLLALVTLVAKKALEWRQRSARAAARRSHA

Sequences:

>Translated_283_residues
MSARVANQDPAAVRWALTGLALAFLAAFVLVPAAAVLWEAVRGGAQVWWAAVTDPDARAAIRLTLLVAAWSVPLNTAFGI
AAAWSLTRFRFRGKSLLVSLVDLPFGVSPVISGMVTVLLFGAQGWLGPWLDAHGLKVVFAVPGIVLATVFVTFPFVAREL
IPFMEAQGVEEEEAALVLGASGWQILSRVTLPNVKWSLLYGVVLCNARAMGEFGAVSVVSGHVRGVTNTIPLHVEILYDE
YAFRASFAVASLLFLLALVTLVAKKALEWRQRSARAAARRSHA
>Mature_282_residues
SARVANQDPAAVRWALTGLALAFLAAFVLVPAAAVLWEAVRGGAQVWWAAVTDPDARAAIRLTLLVAAWSVPLNTAFGIA
AAWSLTRFRFRGKSLLVSLVDLPFGVSPVISGMVTVLLFGAQGWLGPWLDAHGLKVVFAVPGIVLATVFVTFPFVARELI
PFMEAQGVEEEEAALVLGASGWQILSRVTLPNVKWSLLYGVVLCNARAMGEFGAVSVVSGHVRGVTNTIPLHVEILYDEY
AFRASFAVASLLFLLALVTLVAKKALEWRQRSARAAARRSHA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=271, Percent_Identity=49.8154981549816, Blast_Score=272, Evalue=1e-74,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=38.3495145631068, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786980, Length=231, Percent_Identity=33.7662337662338, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30358; Mature: 30227

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARVANQDPAAVRWALTGLALAFLAAFVLVPAAAVLWEAVRGGAQVWWAAVTDPDARAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHH
IRLTLLVAAWSVPLNTAFGIAAAWSLTRFRFRGKSLLVSLVDLPFGVSPVISGMVTVLLF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
GAQGWLGPWLDAHGLKVVFAVPGIVLATVFVTFPFVARELIPFMEAQGVEEEEAALVLGA
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
SGWQILSRVTLPNVKWSLLYGVVLCNARAMGEFGAVSVVSGHVRGVTNTIPLHVEILYDE
CHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHHCCCCCCCCCCCEEEEEEEHH
YAFRASFAVASLLFLLALVTLVAKKALEWRQRSARAAARRSHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SARVANQDPAAVRWALTGLALAFLAAFVLVPAAAVLWEAVRGGAQVWWAAVTDPDARAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHH
IRLTLLVAAWSVPLNTAFGIAAAWSLTRFRFRGKSLLVSLVDLPFGVSPVISGMVTVLLF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
GAQGWLGPWLDAHGLKVVFAVPGIVLATVFVTFPFVARELIPFMEAQGVEEEEAALVLGA
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
SGWQILSRVTLPNVKWSLLYGVVLCNARAMGEFGAVSVVSGHVRGVTNTIPLHVEILYDE
CHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHHCCCCCCCCCCCEEEEEEEHH
YAFRASFAVASLLFLLALVTLVAKKALEWRQRSARAAARRSHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]