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The map label for this gene is pheA [H]

Identifier: 220917255

GI number: 220917255

Start: 2392717

End: 2393550

Strand: Direct

Name: pheA [H]

Synonym: A2cp1_2153

Alternate gene names: 220917255

Gene position: 2392717-2393550 (Clockwise)

Preceding gene: 220917254

Following gene: 220917259

Centisome position: 47.58

GC content: 76.38

Gene sequence:

>834_bases
ATGCGCGTCGGATACCTCGGCCCCCCGGGCACCTTCAGCGAGGAGGCGGTCGCGCGCTGCGAGGCGGTCCGCGGCGCGGA
GGCGGTGCCGTTCCCCACCTTCGCGGACGCGCACGAGGCGCTGCTGCGCGGGGAGCTCGACGCCGCGCTGCTGCCCATCG
AGAACTCGATCGAGGGCGCGGTGAGCGCGGTGCTCGACCTGCTGGTGCACCGGCCCGGCGCCCGCATCCGGGCCGAGCTG
CTGCTGCAGGTCCGCCAGCACCTGCTGGCCCGGCCCGGCACGCGGCTGGAGCAGGTGCGGCGCGTGCTCTCGCACCCGCA
GCCGCTCGGGCAGTGCGCCCGCTTCCTGAGGGCGCGGCTGCCCGCGGCGGCGCTCGAGCCGGCGCTCTCGACCGCGGAGG
CCGCGCGCAAGGTGGCCGCCGGCGAGCCGGACGCGGCGGCGCTCGGCCCGCGCCGCGCCGCCGAGCGCTACGGCCTGGAG
GTGCTGGCGGAGAACGTCCAGGACTCCGACGAGAACGTGACGCGGTTCGTGCTGCTGGCGCGCGAGGACGCCCCGCCGAG
CGGCGCCGACCGGACCAGCATCGCCTTCACGCTCGATCGCGACCGGCCGGGCGGGCTGTACGAGGTGATGGGCGAGTTCG
CCCGCCGCGGGATCAACCTGTCCAAGATCGAGAGCCGGCCCACCAAGCAGGCCATGGGCCACTACGTGTTCTACCTGGAC
TTCGAGGGGCACCGCGCGGACCCCGCCGGCGCGAGCGCGCTCGAGGGCGTGCGCGAGCAGGTGCACGAGCTGCACCTCCT
GGGCTCGTACCCGCGCACCGGCGCGCCGGTCTAG

Upstream 100 bases:

>100_bases
CTCCTCGAGGACATCGCGGCCCTGCCGGCGCTGCTCGAGGCCATCACCCAGGGTGCATGAGGCGGCGCGCCCGCGCCGTT
CCGTGATAGGAGTCGCGAGC

Downstream 100 bases:

>100_bases
CCGGCCCGGGCGGCCGCGAGCAGCCGCCGGAGCGCCGCGAGGTGCCCGGGCCCGGCGCCGCAGCAGCCTCCGGCGACCCC
CAGGCCCGCATGGACGGCGG

Product: Prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRVGYLGPPGTFSEEAVARCEAVRGAEAVPFPTFADAHEALLRGELDAALLPIENSIEGAVSAVLDLLVHRPGARIRAEL
LLQVRQHLLARPGTRLEQVRRVLSHPQPLGQCARFLRARLPAAALEPALSTAEAARKVAAGEPDAAALGPRRAAERYGLE
VLAENVQDSDENVTRFVLLAREDAPPSGADRTSIAFTLDRDRPGGLYEVMGEFARRGINLSKIESRPTKQAMGHYVFYLD
FEGHRADPAGASALEGVREQVHELHLLGSYPRTGAPV

Sequences:

>Translated_277_residues
MRVGYLGPPGTFSEEAVARCEAVRGAEAVPFPTFADAHEALLRGELDAALLPIENSIEGAVSAVLDLLVHRPGARIRAEL
LLQVRQHLLARPGTRLEQVRRVLSHPQPLGQCARFLRARLPAAALEPALSTAEAARKVAAGEPDAAALGPRRAAERYGLE
VLAENVQDSDENVTRFVLLAREDAPPSGADRTSIAFTLDRDRPGGLYEVMGEFARRGINLSKIESRPTKQAMGHYVFYLD
FEGHRADPAGASALEGVREQVHELHLLGSYPRTGAPV
>Mature_277_residues
MRVGYLGPPGTFSEEAVARCEAVRGAEAVPFPTFADAHEALLRGELDAALLPIENSIEGAVSAVLDLLVHRPGARIRAEL
LLQVRQHLLARPGTRLEQVRRVLSHPQPLGQCARFLRARLPAAALEPALSTAEAARKVAAGEPDAAALGPRRAAERYGLE
VLAENVQDSDENVTRFVLLAREDAPPSGADRTSIAFTLDRDRPGGLYEVMGEFARRGINLSKIESRPTKQAMGHYVFYLD
FEGHRADPAGASALEGVREQVHELHLLGSYPRTGAPV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=279, Percent_Identity=34.0501792114695, Blast_Score=131, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 29954; Mature: 29954

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGYLGPPGTFSEEAVARCEAVRGAEAVPFPTFADAHEALLRGELDAALLPIENSIEGA
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHH
VSAVLDLLVHRPGARIRAELLLQVRQHLLARPGTRLEQVRRVLSHPQPLGQCARFLRARL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHC
PAAALEPALSTAEAARKVAAGEPDAAALGPRRAAERYGLEVLAENVQDSDENVTRFVLLA
CHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
REDAPPSGADRTSIAFTLDRDRPGGLYEVMGEFARRGINLSKIESRPTKQAMGHYVFYLD
ECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHCCEEEEEE
FEGHRADPAGASALEGVREQVHELHLLGSYPRTGAPV
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVGYLGPPGTFSEEAVARCEAVRGAEAVPFPTFADAHEALLRGELDAALLPIENSIEGA
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHH
VSAVLDLLVHRPGARIRAELLLQVRQHLLARPGTRLEQVRRVLSHPQPLGQCARFLRARL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHC
PAAALEPALSTAEAARKVAAGEPDAAALGPRRAAERYGLEVLAENVQDSDENVTRFVLLA
CHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
REDAPPSGADRTSIAFTLDRDRPGGLYEVMGEFARRGINLSKIESRPTKQAMGHYVFYLD
ECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHCCEEEEEE
FEGHRADPAGASALEGVREQVHELHLLGSYPRTGAPV
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]