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The map label for this gene is ppaX [H]

Identifier: 220917254

GI number: 220917254

Start: 2391999

End: 2392676

Strand: Direct

Name: ppaX [H]

Synonym: A2cp1_2152

Alternate gene names: 220917254

Gene position: 2391999-2392676 (Clockwise)

Preceding gene: 220917251

Following gene: 220917255

Centisome position: 47.56

GC content: 74.78

Gene sequence:

>678_bases
ATGATGGCGGACGTGCCAGAACACCGCCGGATGGCGATCCTGTTCGATCTGGACGGGACGCTCGTCGACACCGTTCCGTT
CATCCTCGCCTCCGTGCGCCACGCCTTCGACGGGTACGGGAGCTGCCCGACCGACGCCGAGTGGATCGCCGGGATCGGGA
CGCCGCTCCGCACCCAGCTCGCCTCGTTCGCCCGCTGCGCCGAGGACGTCGAGCCCTTGCTCGCGCGCTACCGCTCCTTC
TGGATCGCGGAGCACGATCGCTGGACGCGCTGCTTCCCCTCGGCGCGCGAGACGGTGCTGACGCTCGCGGGCCGGGGCCA
TCCCCTCGGCGTGGTGACGGCGAAGACCGAGGAGGGCGCCTACCGCACGCTCCGCCACGTGGGGCTGCTCGAGCGGATGG
GGGCCGTGATCGGGGCGGACAGCTGCGCCCGCTCGAAGCCCGACCCCGAGCCGGTGCGGCTCGCGCTGGCGCGGCTGGGC
GTCGGCGCGGACGAGGCGGTGATGGTGGGCGACTCGCCGCACGACCTGGCGGCCGGCCGGGCGGCGGGCGTGCGGACGGT
GGCCGCGCTGTGGGGCGCCTGCACGCCCTCGGTGCTCCGCGCCGCCTCCCCCGACCACCTCCTCGAGGACATCGCGGCCC
TGCCGGCGCTGCTCGAGGCCATCACCCAGGGTGCATGA

Upstream 100 bases:

>100_bases
GCACCTCCGCCGCCCCATCCGACCGCCGAACGATCGCCGCTCCCGTCATCGCGCACCGAAATTAGGCACGATCGTCGGGA
GGGGATGGGGAATTTTCACT

Downstream 100 bases:

>100_bases
GGCGGCGCGCCCGCGCCGTTCCGTGATAGGAGTCGCGAGCATGCGCGTCGGATACCTCGGCCCCCCGGGCACCTTCAGCG
AGGAGGCGGTCGCGCGCTGC

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MMADVPEHRRMAILFDLDGTLVDTVPFILASVRHAFDGYGSCPTDAEWIAGIGTPLRTQLASFARCAEDVEPLLARYRSF
WIAEHDRWTRCFPSARETVLTLAGRGHPLGVVTAKTEEGAYRTLRHVGLLERMGAVIGADSCARSKPDPEPVRLALARLG
VGADEAVMVGDSPHDLAAGRAAGVRTVAALWGACTPSVLRAASPDHLLEDIAALPALLEAITQGA

Sequences:

>Translated_225_residues
MMADVPEHRRMAILFDLDGTLVDTVPFILASVRHAFDGYGSCPTDAEWIAGIGTPLRTQLASFARCAEDVEPLLARYRSF
WIAEHDRWTRCFPSARETVLTLAGRGHPLGVVTAKTEEGAYRTLRHVGLLERMGAVIGADSCARSKPDPEPVRLALARLG
VGADEAVMVGDSPHDLAAGRAAGVRTVAALWGACTPSVLRAASPDHLLEDIAALPALLEAITQGA
>Mature_225_residues
MMADVPEHRRMAILFDLDGTLVDTVPFILASVRHAFDGYGSCPTDAEWIAGIGTPLRTQLASFARCAEDVEPLLARYRSF
WIAEHDRWTRCFPSARETVLTLAGRGHPLGVVTAKTEEGAYRTLRHVGLLERMGAVIGADSCARSKPDPEPVRLALARLG
VGADEAVMVGDSPHDLAAGRAAGVRTVAALWGACTPSVLRAASPDHLLEDIAALPALLEAITQGA

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=231, Percent_Identity=28.1385281385281, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 24017; Mature: 24017

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMADVPEHRRMAILFDLDGTLVDTVPFILASVRHAFDGYGSCPTDAEWIAGIGTPLRTQL
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHH
ASFARCAEDVEPLLARYRSFWIAEHDRWTRCFPSARETVLTLAGRGHPLGVVTAKTEEGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCHH
YRTLRHVGLLERMGAVIGADSCARSKPDPEPVRLALARLGVGADEAVMVGDSPHDLAAGR
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHCH
AAGVRTVAALWGACTPSVLRAASPDHLLEDIAALPALLEAITQGA
HHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMADVPEHRRMAILFDLDGTLVDTVPFILASVRHAFDGYGSCPTDAEWIAGIGTPLRTQL
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHH
ASFARCAEDVEPLLARYRSFWIAEHDRWTRCFPSARETVLTLAGRGHPLGVVTAKTEEGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCCCCCEEEEEECCCCHH
YRTLRHVGLLERMGAVIGADSCARSKPDPEPVRLALARLGVGADEAVMVGDSPHDLAAGR
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHCH
AAGVRTVAALWGACTPSVLRAASPDHLLEDIAALPALLEAITQGA
HHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA