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The map label for this gene is pheS [H]

Identifier: 220917094

GI number: 220917094

Start: 2246719

End: 2247828

Strand: Direct

Name: pheS [H]

Synonym: A2cp1_1991

Alternate gene names: 220917094

Gene position: 2246719-2247828 (Clockwise)

Preceding gene: 220917093

Following gene: 220917095

Centisome position: 44.67

GC content: 73.06

Gene sequence:

>1110_bases
ATGGCCGACCTGCTCTCGCAGCTCGAGGCGCTCGCACGGAGCGCCCGTGAAGCCATCGCCTCCGCCGCGGACGAGAAGGG
GCTCGAGGAGCTCCGCGTCCGCTTCCTCGGCAAGAAGGGCGAGCTGTCCCAGGTCCTCCGGGGCATGGGGCAGCTCCCCG
CCGAGGAGCGCCCGCGCGTCGGCGAGGTCGCGAACCGCGTCCGCGACGAGGTCGAGGCGCTGCTCGCCGGCGCCGCGCGC
GGCGTCGCCGCGCGCGCGCTCGAGGCCGAGCTCGCCGGCCCGCCCATGGACGTGACGCTGTCCGGCCGCCGGCTCCTGCC
GCGCGGGCACCGGCACCCCGTCACGCGCGCCACCGAGGACATCTCCGCCATCTTCGCGCGCCTCGGCTACGAGGTCGCGA
GCGGGCCGGAGATCGAGCTCGACTGGTACAACTTCGAGGCGCTCAACATCCCGCCGGACCACCCCGCGCGCGACATGCAG
GACACGTTCTACGTGGACGAGTCCACCCTGTCGCCGGGCGGGCGCACCGGCGTTGCGCCGGGCGGGCCCGCGAGGCCGGG
GGCGGTGCTGCTCCGCACGCACACCTCGCCGGTGCAGATCCGCGCCATGAAGCGGATCGGCGGACCGCCCATCCGCATCA
TCTGCCCGGGCCGCGTCTACCGGTCGGACTACGACCAGACCCACTCGCCCATGTTCCACCAGATCGAGGGGCTGTGCGTG
GACGAGGGCATCACCTTCGCCGACCTGAAGGGCACCCTGGCGGCGTTCGCCCGCGCCTACTTCGGCCCGGGCACCCGCAC
GCGCTTCCGGCCCAGCTACTTCCCGTTCACCGAGCCGAGCGCCGAGGTGGACGTGTCGTGCTCGATCTGCGGCGGCACCG
GGCGCAAGGACGGCAAGCGCTGCGGCACGTGCAAGGAGACCGGCTGGCTGGAGGTGCTCGGCGCCGGCATGGTCCACCCG
CGCGTGCTCGAGAACGGCGGCGTGGATCCGCGCCGCTTCACCGGCTTCGCCTTCGGCATGGGGGTCGAGCGCATGGCGAT
GCTCCGCTACGGCATCGACGACCTGCGCCTGTACTTCGAGAACGACCTCCGCTTCCTCGAACAGTTCTGA

Upstream 100 bases:

>100_bases
CATCGAGATCGACCGCAAGATCCTCGCCGATCTCGCGCTCGCCCTCCCGGGCGACTTCGCCGCCATCGTCAAGACCGCCC
AGGCGTAGGGGAGGGGTCCG

Downstream 100 bases:

>100_bases
GAACGCCGTGCGCATCTCGCTCAAGTGGCTATCGGAGTACGTGGACCTGCCCGCGCCCGAGGAGCTGGCGCGGCGCCTCA
CCGCCGTGGGCTTCGAGATC

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MADLLSQLEALARSAREAIASAADEKGLEELRVRFLGKKGELSQVLRGMGQLPAEERPRVGEVANRVRDEVEALLAGAAR
GVAARALEAELAGPPMDVTLSGRRLLPRGHRHPVTRATEDISAIFARLGYEVASGPEIELDWYNFEALNIPPDHPARDMQ
DTFYVDESTLSPGGRTGVAPGGPARPGAVLLRTHTSPVQIRAMKRIGGPPIRIICPGRVYRSDYDQTHSPMFHQIEGLCV
DEGITFADLKGTLAAFARAYFGPGTRTRFRPSYFPFTEPSAEVDVSCSICGGTGRKDGKRCGTCKETGWLEVLGAGMVHP
RVLENGGVDPRRFTGFAFGMGVERMAMLRYGIDDLRLYFENDLRFLEQF

Sequences:

>Translated_369_residues
MADLLSQLEALARSAREAIASAADEKGLEELRVRFLGKKGELSQVLRGMGQLPAEERPRVGEVANRVRDEVEALLAGAAR
GVAARALEAELAGPPMDVTLSGRRLLPRGHRHPVTRATEDISAIFARLGYEVASGPEIELDWYNFEALNIPPDHPARDMQ
DTFYVDESTLSPGGRTGVAPGGPARPGAVLLRTHTSPVQIRAMKRIGGPPIRIICPGRVYRSDYDQTHSPMFHQIEGLCV
DEGITFADLKGTLAAFARAYFGPGTRTRFRPSYFPFTEPSAEVDVSCSICGGTGRKDGKRCGTCKETGWLEVLGAGMVHP
RVLENGGVDPRRFTGFAFGMGVERMAMLRYGIDDLRLYFENDLRFLEQF
>Mature_368_residues
ADLLSQLEALARSAREAIASAADEKGLEELRVRFLGKKGELSQVLRGMGQLPAEERPRVGEVANRVRDEVEALLAGAARG
VAARALEAELAGPPMDVTLSGRRLLPRGHRHPVTRATEDISAIFARLGYEVASGPEIELDWYNFEALNIPPDHPARDMQD
TFYVDESTLSPGGRTGVAPGGPARPGAVLLRTHTSPVQIRAMKRIGGPPIRIICPGRVYRSDYDQTHSPMFHQIEGLCVD
EGITFADLKGTLAAFARAYFGPGTRTRFRPSYFPFTEPSAEVDVSCSICGGTGRKDGKRCGTCKETGWLEVLGAGMVHPR
VLENGGVDPRRFTGFAFGMGVERMAMLRYGIDDLRLYFENDLRFLEQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=276, Percent_Identity=32.2463768115942, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI5729820, Length=317, Percent_Identity=28.391167192429, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1788007, Length=365, Percent_Identity=51.5068493150685, Blast_Score=354, Evalue=5e-99,
Organism=Caenorhabditis elegans, GI17508957, Length=275, Percent_Identity=30.1818181818182, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32563657, Length=275, Percent_Identity=30.1818181818182, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI32566635, Length=278, Percent_Identity=32.0143884892086, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321087, Length=293, Percent_Identity=29.6928327645051, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6325304, Length=104, Percent_Identity=34.6153846153846, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18858079, Length=275, Percent_Identity=30.5454545454545, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI17137424, Length=275, Percent_Identity=28.7272727272727, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 40404; Mature: 40272

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLLSQLEALARSAREAIASAADEKGLEELRVRFLGKKGELSQVLRGMGQLPAEERPRV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCH
GEVANRVRDEVEALLAGAARGVAARALEAELAGPPMDVTLSGRRLLPRGHRHPVTRATED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHH
ISAIFARLGYEVASGPEIELDWYNFEALNIPPDHPARDMQDTFYVDESTLSPGGRTGVAP
HHHHHHHHCCHHCCCCEEEEEEEEEEEECCCCCCCCCCCCHHEEEECCCCCCCCCCCCCC
GGPARPGAVLLRTHTSPVQIRAMKRIGGPPIRIICPGRVYRSDYDQTHSPMFHQIEGLCV
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCHHHHCCCCCCCCCHHHHHCCEEE
DEGITFADLKGTLAAFARAYFGPGTRTRFRPSYFPFTEPSAEVDVSCSICGGTGRKDGKR
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCC
CGTCKETGWLEVLGAGMVHPRVLENGGVDPRRFTGFAFGMGVERMAMLRYGIDDLRLYFE
CCCCCCCCHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHH
NDLRFLEQF
HHHHHHHCC
>Mature Secondary Structure 
ADLLSQLEALARSAREAIASAADEKGLEELRVRFLGKKGELSQVLRGMGQLPAEERPRV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCH
GEVANRVRDEVEALLAGAARGVAARALEAELAGPPMDVTLSGRRLLPRGHRHPVTRATED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHH
ISAIFARLGYEVASGPEIELDWYNFEALNIPPDHPARDMQDTFYVDESTLSPGGRTGVAP
HHHHHHHHCCHHCCCCEEEEEEEEEEEECCCCCCCCCCCCHHEEEECCCCCCCCCCCCCC
GGPARPGAVLLRTHTSPVQIRAMKRIGGPPIRIICPGRVYRSDYDQTHSPMFHQIEGLCV
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCHHHHCCCCCCCCCHHHHHCCEEE
DEGITFADLKGTLAAFARAYFGPGTRTRFRPSYFPFTEPSAEVDVSCSICGGTGRKDGKR
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCC
CGTCKETGWLEVLGAGMVHPRVLENGGVDPRRFTGFAFGMGVERMAMLRYGIDDLRLYFE
CCCCCCCCHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHH
NDLRFLEQF
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA