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The map label for this gene is infC [H]

Identifier: 220917091

GI number: 220917091

Start: 2245302

End: 2245994

Strand: Direct

Name: infC [H]

Synonym: A2cp1_1988

Alternate gene names: 220917091

Gene position: 2245302-2245994 (Clockwise)

Preceding gene: 220917090

Following gene: 220917092

Centisome position: 44.64

GC content: 71.0

Gene sequence:

>693_bases
ATGGCGATCCAGCACAGAGATCCGCGGGGCGGCGGCGGCAGCCGCGATGCGCGCACCAACCGCCGCATCAAGGCCCGCGA
GGTACGCGTCATCGGGGCCGAGGGCGAGCAGCTCGGCGTGCTCCCGATCGACCAGGCGCTGGCGCGCGCGCAGGAGCTGG
GCATGGACCTCGTCGAGGTCAGCCCGATGGCGAAGCCGCCCGTCTGCAAGATCATGGACTACGGCCGCTTCAAGTACCTC
GAGAAGAAGAAGCAGAACGAGGCCAAGAAGAAGCAGGTCGTGGTGCAGCTCAAGGAAGTGAAGCTCCGCCCGCGCACGGA
GGAGCACGACTACGACACCAAGATCAAGAAGGTGCGCGCGTTCCTCGGCGAGGCGAACAAGGCGCGCATCACCGTGATGT
TCCGCGGGCGCGAGATGTCCCACCGCGAGCTGGGCCAGAAGGTCCTGCAGCGGGTGATCGAGGATCTGCGCGACGTGGCG
GTCATCGAGTCGGCGCCCCGCATGGAAGGGCGCCAGATGTTCATGATCCTCGCGCCGAACCCGAAGATGCTCCAGTCCCA
GCGCGACAAGGCCAAGGCCGCGGCCGCCGCGGCGCCCGCCGCTGCCCCCGCCGCCGGCGCGCCCGCGCCGGCCCCGGCTC
CCGCCGCCCCGGCGCCCGCGCCGACCGCCGCGGACCCGGCGGCACAGAGATAG

Upstream 100 bases:

>100_bases
CACGAGGGGAAGGGGACGCGCGCGCACGGGCGCACGGCCGCGTTGACATTGCGGCCGAAATCCTTATTCTACAGCGTCTT
TTTCCGAGGGCCGGAGGAGC

Downstream 100 bases:

>100_bases
ACAGCACCGCCGCGCGCAGGCGCGGCGCACGACGCAGCAGCGAACAGGAAGCGACAGGACCCATGCCCAAGCTGAAGACC
AAGAGCGGCGCCAAGAAGCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MAIQHRDPRGGGGSRDARTNRRIKAREVRVIGAEGEQLGVLPIDQALARAQELGMDLVEVSPMAKPPVCKIMDYGRFKYL
EKKKQNEAKKKQVVVQLKEVKLRPRTEEHDYDTKIKKVRAFLGEANKARITVMFRGREMSHRELGQKVLQRVIEDLRDVA
VIESAPRMEGRQMFMILAPNPKMLQSQRDKAKAAAAAAPAAAPAAGAPAPAPAPAAPAPAPTAADPAAQR

Sequences:

>Translated_230_residues
MAIQHRDPRGGGGSRDARTNRRIKAREVRVIGAEGEQLGVLPIDQALARAQELGMDLVEVSPMAKPPVCKIMDYGRFKYL
EKKKQNEAKKKQVVVQLKEVKLRPRTEEHDYDTKIKKVRAFLGEANKARITVMFRGREMSHRELGQKVLQRVIEDLRDVA
VIESAPRMEGRQMFMILAPNPKMLQSQRDKAKAAAAAAPAAAPAAGAPAPAPAPAAPAPAPTAADPAAQR
>Mature_229_residues
AIQHRDPRGGGGSRDARTNRRIKAREVRVIGAEGEQLGVLPIDQALARAQELGMDLVEVSPMAKPPVCKIMDYGRFKYLE
KKKQNEAKKKQVVVQLKEVKLRPRTEEHDYDTKIKKVRAFLGEANKARITVMFRGREMSHRELGQKVLQRVIEDLRDVAV
IESAPRMEGRQMFMILAPNPKMLQSQRDKAKAAAAAAPAAAPAAGAPAPAPAPAAPAPAPTAADPAAQR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=170, Percent_Identity=54.1176470588235, Blast_Score=179, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 25192; Mature: 25060

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQHRDPRGGGGSRDARTNRRIKAREVRVIGAEGEQLGVLPIDQALARAQELGMDLVEV
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCHHHHHHHHHHHCCHHHHC
SPMAKPPVCKIMDYGRFKYLEKKKQNEAKKKQVVVQLKEVKLRPRTEEHDYDTKIKKVRA
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FLGEANKARITVMFRGREMSHRELGQKVLQRVIEDLRDVAVIESAPRMEGRQMFMILAPN
HHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
PKMLQSQRDKAKAAAAAAPAAAPAAGAPAPAPAPAAPAPAPTAADPAAQR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIQHRDPRGGGGSRDARTNRRIKAREVRVIGAEGEQLGVLPIDQALARAQELGMDLVEV
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCHHHHHHHHHHHCCHHHHC
SPMAKPPVCKIMDYGRFKYLEKKKQNEAKKKQVVVQLKEVKLRPRTEEHDYDTKIKKVRA
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FLGEANKARITVMFRGREMSHRELGQKVLQRVIEDLRDVAVIESAPRMEGRQMFMILAPN
HHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
PKMLQSQRDKAKAAAAAAPAAAPAAGAPAPAPAPAAPAPAPTAADPAAQR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA