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The map label for this gene is htpX [H]

Identifier: 220917049

GI number: 220917049

Start: 2199675

End: 2200574

Strand: Reverse

Name: htpX [H]

Synonym: A2cp1_1945

Alternate gene names: 220917049

Gene position: 2200574-2199675 (Counterclockwise)

Preceding gene: 220917050

Following gene: 220917048

Centisome position: 43.75

GC content: 74.78

Gene sequence:

>900_bases
TTGAAGAACCAGCTGAAGACCATCCTGCTCCTCGGCACGCTCTCGGCGCTGCTGGTCGCGTTCGGCGCCAGCCTGGGACC
GGGGCCGTTCTGGCTGTTCACCGCGCTCGCGGTGCTGATGAACCTCGGCGCGTACTTCTTCTCGGACAAGCTCGTGCTGC
GCATGCACCGCGCCCGCGAGCTGGCGCCCGGGGAGGCGCCGCGGCTGCACGAGATCGTCCGCGAGCTGTCGGGCCGGGCC
GGCATCCCCCCGCCGCGGCTGTTCGTCATCGACGAGCCGCACGCGAACGCGTTCGCGACCGGGCGCAACCCGCGGCACGC
GGTGGTGGCGGTGACGCGGGGCATCGTGGACCTGCTCGACGAGCGCGAGCTGCGCGGCGTGATCGCGCACGAGCTCGCGC
ACGTGGCGAACCGGGACATCCTGGTGGCGAGCGTGGCCGCCGGCATGGCGGCGGCCATCTCGAACCTCGCCAACATGATC
ATGTTCTCGAGCCTGCTCGGCGGCGGCCGCGAGGACGAGGAGGGCGGCGGCGGCGGGCTGCTCATGATGCTCGTCGCGCC
CATCGCCGGCACGCTGGTGCAGCTCGGCATCTCGCGCTCGCGCGAGTACCTCGCCGACGAGACCGGGGCGCGCATCAGCG
GCGACCCGCTCGCGCTGGCGAGCGCGCTCGAGAAGCTGCAGCGCGGCGCCGAGGTGGTCCCGGCCGCGGCGGGCGCGCCC
GCCACCGCCAGCCTGTTCATCGTCAACCCGTTCGGCGCCGGCGCCGTGATGGGCGGCCTGGCCCGCCTGTTCTCGACGCA
CCCGCCCGCCGAGGAGCGCATCCGGCGGCTCCGCGAGCTGGCGCGCGTGGCCGGCGGCGCCGACGGGTACGGCCCGCGCT
CGCGGATGGTGCGCGGCTGA

Upstream 100 bases:

>100_bases
GTTTTCTCGCAGGCTCGCGCCAACATTTTCTATTTGTCTGCGTCAGGCCAGCGACTAGGTTCTCCCTGCGCGCGCACCGT
CGCGCGGCGGAGGCCACACC

Downstream 100 bases:

>100_bases
TCGAAGGATTCCTCCATCGGAAGCCGGCGCGGAACACGGACCGCGCCGGCCGCCGCGGGGGCGGCGCCCGGTCCTGCTGG
GCGGGGACCGGGCGCCGCGT

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKNQLKTILLLGTLSALLVAFGASLGPGPFWLFTALAVLMNLGAYFFSDKLVLRMHRARELAPGEAPRLHEIVRELSGRA
GIPPPRLFVIDEPHANAFATGRNPRHAVVAVTRGIVDLLDERELRGVIAHELAHVANRDILVASVAAGMAAAISNLANMI
MFSSLLGGGREDEEGGGGGLLMMLVAPIAGTLVQLGISRSREYLADETGARISGDPLALASALEKLQRGAEVVPAAAGAP
ATASLFIVNPFGAGAVMGGLARLFSTHPPAEERIRRLRELARVAGGADGYGPRSRMVRG

Sequences:

>Translated_299_residues
MKNQLKTILLLGTLSALLVAFGASLGPGPFWLFTALAVLMNLGAYFFSDKLVLRMHRARELAPGEAPRLHEIVRELSGRA
GIPPPRLFVIDEPHANAFATGRNPRHAVVAVTRGIVDLLDERELRGVIAHELAHVANRDILVASVAAGMAAAISNLANMI
MFSSLLGGGREDEEGGGGGLLMMLVAPIAGTLVQLGISRSREYLADETGARISGDPLALASALEKLQRGAEVVPAAAGAP
ATASLFIVNPFGAGAVMGGLARLFSTHPPAEERIRRLRELARVAGGADGYGPRSRMVRG
>Mature_299_residues
MKNQLKTILLLGTLSALLVAFGASLGPGPFWLFTALAVLMNLGAYFFSDKLVLRMHRARELAPGEAPRLHEIVRELSGRA
GIPPPRLFVIDEPHANAFATGRNPRHAVVAVTRGIVDLLDERELRGVIAHELAHVANRDILVASVAAGMAAAISNLANMI
MFSSLLGGGREDEEGGGGGLLMMLVAPIAGTLVQLGISRSREYLADETGARISGDPLALASALEKLQRGAEVVPAAAGAP
ATASLFIVNPFGAGAVMGGLARLFSTHPPAEERIRRLRELARVAGGADGYGPRSRMVRG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=211, Percent_Identity=29.8578199052133, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31411; Mature: 31411

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQLKTILLLGTLSALLVAFGASLGPGPFWLFTALAVLMNLGAYFFSDKLVLRMHRARE
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPGEAPRLHEIVRELSGRAGIPPPRLFVIDEPHANAFATGRNPRHAVVAVTRGIVDLLD
CCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHH
ERELRGVIAHELAHVANRDILVASVAAGMAAAISNLANMIMFSSLLGGGREDEEGGGGGL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LMMLVAPIAGTLVQLGISRSREYLADETGARISGDPLALASALEKLQRGAEVVPAAAGAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
ATASLFIVNPFGAGAVMGGLARLFSTHPPAEERIRRLRELARVAGGADGYGPRSRMVRG
CEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCCCC
>Mature Secondary Structure
MKNQLKTILLLGTLSALLVAFGASLGPGPFWLFTALAVLMNLGAYFFSDKLVLRMHRARE
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPGEAPRLHEIVRELSGRAGIPPPRLFVIDEPHANAFATGRNPRHAVVAVTRGIVDLLD
CCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHH
ERELRGVIAHELAHVANRDILVASVAAGMAAAISNLANMIMFSSLLGGGREDEEGGGGGL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LMMLVAPIAGTLVQLGISRSREYLADETGARISGDPLALASALEKLQRGAEVVPAAAGAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
ATASLFIVNPFGAGAVMGGLARLFSTHPPAEERIRRLRELARVAGGADGYGPRSRMVRG
CEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA