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The map label for this gene is nhaR [H]

Identifier: 220917050

GI number: 220917050

Start: 2200914

End: 2201822

Strand: Reverse

Name: nhaR [H]

Synonym: A2cp1_1946

Alternate gene names: 220917050

Gene position: 2201822-2200914 (Counterclockwise)

Preceding gene: 220917052

Following gene: 220917049

Centisome position: 43.78

GC content: 74.04

Gene sequence:

>909_bases
ATGGAATGGCTGAACTACCATCACCTCTTCTACTTCTGGACGGTGGCCCGCGCCGGCAGCATCGCGCGCGCCAGCGAGGA
GCTGCGGCTCGCGCAGCCCACCATCTCGAACCAGCTCAAGACGCTGGAGGCGAACCTCGGGGTGAAGCTCCTGGAGCGGC
AGGGGCGGCGGCTCGTCCTCACCGACGTGGGACGGACCGTGCTCCGCTACGCGGACGACATCTTCCGGACCGGGCGCGAG
CTGCAGCGGGCGGTGAAGGGCCTCCCCACCGGCCAGCGGCTTCGCCTGGTGGTCGGCGTGGCCGACGTGATCCCGAAGCG
CATGGCCGCGCTGCTGCTGCAGCCGGCGGTGGACGCGCACCCGGACCTGACGCTGGTCTGCCGCGAGGGCCCGCTGCCGC
AGCTGCTCGCGGCGCTGGCGCTGCACGAGCTCGACGTCGTCATCGCCGACGTCCCCGCGCCGGAGGACGTGAAGGTGAAG
GCGTTCAGCCACCGGCTCGGCGACTGCGGGACCTCGTTCCTGGCGGCGCGGCCGCTCGCGCATCTCAAGAAGGGCTTCCC
GCGGTCGCTCCAGGCCGCGCCCATGCTCCTGCCGTCGGAGGGCACCGCGCTCCGGCGCGGGCTCGACACCTGGCTCGAGC
GCACCGGCGTGCGCCCGGTGGTCGCGGGCGAGTTCGACGACAGCGCGCTCATGCAGGCGTTCGGCGCGCGCGGGCTGGGC
GTGTTCGCCGCCCCGCGCGTGCTGGAGGACGACATCCGCTCGCAGCTCGAGGTGGGCGTGATCGGGCGGGCCGAGGACGT
GCGCGAGGCCTACCACGCGATCACCGTGGAGCGCCGGCTGCGCCACCCGGCGGTGGTCACCCTGGCCGAGGCGGCGCGCG
ACGCGATCTTCGGCGCGCCGCAGGCCTGA

Upstream 100 bases:

>100_bases
CGGTCTCGAGCGCGAGGGCGGGAGGGTGCATGAGGCGGCCTTTTTAGACCTTCCGGCGGGTTCGCGCCGGGGAATTCTGG
ATCCGGGTTAGATTTTCTCC

Downstream 100 bases:

>100_bases
GAGCACGTGAACCCATCCCCTCCCGTCGCCGCGGCGGCCGATCCGCGTCGCATCGCTTCGTTGCTCCTCCCTGCACATGC
CTCGGGGCATGCTCGGTCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MEWLNYHHLFYFWTVARAGSIARASEELRLAQPTISNQLKTLEANLGVKLLERQGRRLVLTDVGRTVLRYADDIFRTGRE
LQRAVKGLPTGQRLRLVVGVADVIPKRMAALLLQPAVDAHPDLTLVCREGPLPQLLAALALHELDVVIADVPAPEDVKVK
AFSHRLGDCGTSFLAARPLAHLKKGFPRSLQAAPMLLPSEGTALRRGLDTWLERTGVRPVVAGEFDDSALMQAFGARGLG
VFAAPRVLEDDIRSQLEVGVIGRAEDVREAYHAITVERRLRHPAVVTLAEAARDAIFGAPQA

Sequences:

>Translated_302_residues
MEWLNYHHLFYFWTVARAGSIARASEELRLAQPTISNQLKTLEANLGVKLLERQGRRLVLTDVGRTVLRYADDIFRTGRE
LQRAVKGLPTGQRLRLVVGVADVIPKRMAALLLQPAVDAHPDLTLVCREGPLPQLLAALALHELDVVIADVPAPEDVKVK
AFSHRLGDCGTSFLAARPLAHLKKGFPRSLQAAPMLLPSEGTALRRGLDTWLERTGVRPVVAGEFDDSALMQAFGARGLG
VFAAPRVLEDDIRSQLEVGVIGRAEDVREAYHAITVERRLRHPAVVTLAEAARDAIFGAPQA
>Mature_302_residues
MEWLNYHHLFYFWTVARAGSIARASEELRLAQPTISNQLKTLEANLGVKLLERQGRRLVLTDVGRTVLRYADDIFRTGRE
LQRAVKGLPTGQRLRLVVGVADVIPKRMAALLLQPAVDAHPDLTLVCREGPLPQLLAALALHELDVVIADVPAPEDVKVK
AFSHRLGDCGTSFLAARPLAHLKKGFPRSLQAAPMLLPSEGTALRRGLDTWLERTGVRPVVAGEFDDSALMQAFGARGLG
VFAAPRVLEDDIRSQLEVGVIGRAEDVREAYHAITVERRLRHPAVVTLAEAARDAIFGAPQA

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=298, Percent_Identity=38.255033557047, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=29.6943231441048, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=26.4822134387352, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082024, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788748, Length=256, Percent_Identity=24.21875, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33109; Mature: 33109

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLNYHHLFYFWTVARAGSIARASEELRLAQPTISNQLKTLEANLGVKLLERQGRRLVL
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCEEEE
TDVGRTVLRYADDIFRTGRELQRAVKGLPTGQRLRLVVGVADVIPKRMAALLLQPAVDAH
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHCCCCCC
PDLTLVCREGPLPQLLAALALHELDVVIADVPAPEDVKVKAFSHRLGDCGTSFLAARPLA
CCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HLKKGFPRSLQAAPMLLPSEGTALRRGLDTWLERTGVRPVVAGEFDDSALMQAFGARGLG
HHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCC
VFAAPRVLEDDIRSQLEVGVIGRAEDVREAYHAITVERRLRHPAVVTLAEAARDAIFGAP
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
QA
CC
>Mature Secondary Structure
MEWLNYHHLFYFWTVARAGSIARASEELRLAQPTISNQLKTLEANLGVKLLERQGRRLVL
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHCCCEEEE
TDVGRTVLRYADDIFRTGRELQRAVKGLPTGQRLRLVVGVADVIPKRMAALLLQPAVDAH
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHCCCCCC
PDLTLVCREGPLPQLLAALALHELDVVIADVPAPEDVKVKAFSHRLGDCGTSFLAARPLA
CCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HLKKGFPRSLQAAPMLLPSEGTALRRGLDTWLERTGVRPVVAGEFDDSALMQAFGARGLG
HHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHCCCCCC
VFAAPRVLEDDIRSQLEVGVIGRAEDVREAYHAITVERRLRHPAVVTLAEAARDAIFGAP
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]