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The map label for this gene is fusA2 [H]

Identifier: 220917002

GI number: 220917002

Start: 2129700

End: 2131769

Strand: Reverse

Name: fusA2 [H]

Synonym: A2cp1_1898

Alternate gene names: 220917002

Gene position: 2131769-2129700 (Counterclockwise)

Preceding gene: 220917004

Following gene: 220917001

Centisome position: 42.39

GC content: 74.25

Gene sequence:

>2070_bases
ATGGGGGAGCCACGCGGCGAGGGGACGGCGTCGGAGCGGCGCATGCGCGCCATCCGCAACCTCGGGATCATGGCGCACAT
CGACGCCGGCAAGACGACGCTCACCGAGCGCCTCCTGTTCGTCGCCGGCCGCACCCACAAGATGGGCGAGGTGCACGAGG
GCGCCGCGGTGATGGACTGGATGGACCTCGAGCGCGAGCGCGGGATCACCATCACGTCCGCCGTGACCCGGCTCGAGTGG
CGCGCGCACGAGCTGCACCTCATCGACACGCCCGGCCACGTGGACTTCACCATCGAGGTCGAGCGCTCGCTGCGCGTGCT
CGACGGGGCGGTGGCGGTGTTCGACGCGGCGCACGGGGTGGAGCCGCAGAGCGAGACCGTCTGGCGGCAGGCCGACCGCT
ACCACGTGCCGCGCATCGCGTTCGCGAACAAGATGGACCGCGTCGGCGCCGACCTCGGGCACACGCTCGCCTCGATGCGC
AAGCACTTCCCCGACCACGTGGTCGCGGCGGTGCAGCGGCCGCTCGGCGCGGAGGCGGCCTTCTCCGGCTTCGAGGACCT
GGTCGCCCGGCGCACCGTCCGGTTCGGCGATCCCGACGACCCGCGCGCGTTCACCGCCGAGCCGGGCATCTCGGCCGAGG
GCGAGGCCGAGCGCGCCGCGCTGGTGGCCGCGCTGGCCGACCTCGACGACGCGGCGGCCGAGGCGGTGCTGTCGGACCGC
GACCTCGACGAGGAGGGGCTGCGGTCCGCCATCCGGCGCGCCACGCTCTCGGGCCGGTTCGTGCCGCTGCTGTGCGGCTC
GGCGCTGCGCAACAAGGGCATCCCGCAGGTGCTCGACGCCGTCTGCGACTGGCTCCCCTCCCCGCTCGACGTGCCTCCGC
CGGCCGGCGTCCACCCCGACACCGGCGAGGAGGAGCGGCGCCCTCCGACCGACGGCGCCCCGCTGCTGGCGCTCGCGTTC
AAGGTCTCGCTGCTCGACGAGCGGCGCCGGTACGTGTTCCTGCGCGTGTACTCCGGGCGCGTCGCCGAGGGCGACGCGGT
GTGGAACGCGAGCCAGCGCAAGTTCGAGAAGGTCGGGCGCGTGCTGCTCATGCACGCCGCGCAGAAGGAGCGCGTACCGT
CGCTCGGCGCCGGCCAGCTCTTCGCCGTGGCCGGTCTGAAGGAGACCCGCACCGGCGATACGCTCACCGACAAGGCCCAC
CCGCTGCTGCTCGAGCGGCTCTCGTCCTACGATCCGGTCATCTCCGAGGCCATCGAGGCCGGCTCGCAGAAGGATCGCGA
GCTCCTGCTGGAGGCGCTCGCGCGGGTCGCCGACGAGGATCCGACGTTCCGGTGGGGCGAGGACCCCGACACCGGCCAGC
TGCTCGTCTCCGGCATGGGCGAGCTGCACCTCGACGTCGTGGCCGAGCGGCTCCGGCGGGAGTTCGGGCTCGCGGTCCGC
ACCGGCCAGCCGCAGGTGCTCCTGCGCGAGACGCTGTCGGCGGAGGCCACCGCGGACGCCACCTTCGAGCGCAAGCTCGA
GGACGAGGAGATCTACGGCCAGGTGTCGGTCGCGGTCGGGCCGCTGCCGCGCGGCGGCGGCTTCCGCTTCGAGGTCTCGC
CCGAGGCGGCCGCGCTCCCCTTCCTCCGCCCGGAGGTGCGCCGCATGGCGGAGGACGGCGCGCGCGAGGCGGCCGAGGCG
GGGGCGCTGGAAGGTCACCCGCTGCAGGACGTCCGGGTGACGCTCACCGGCGCGACCTGGCGCGAGGGCGCGTCGAAGCC
GTTCGCGTACAAGGTCGCCGCCGCCGACGCGGTGCGGACGGCCGCCGCGAAGGCCCGCCCGGTGATCCTCGAGCCGCTCA
TGCGCGTCGAGATCGTGCTCCCGTCGGAGCACCTGGGCGAGGTCATCGGGAGCCTCGACCGGCGCAAGGGCACGGTGCTC
GACGTGGCCGATCGGGGCGAGGCGGTCAAGGTGATCACCTGCGAGGCCCCGCTCCGGCGCATGTTCGGCTACGCCACCGA
GCTGCGATCGGCGACGCAGGGGCGCGCGCTGTTCACCATGCGCTTCGACCGCTTCGACGTGGCCGGCTGA

Upstream 100 bases:

>100_bases
CGAACCGCCGCGGATCCGGAACCGGTCGGCGCCGTGGGGATGGACGTATACTTCCCGGAGCGCGCGGCCGGAGGCGGGGC
GGCGGGCGGAGGGTCGGTGC

Downstream 100 bases:

>100_bases
GGCCGCGGTGGGCCGCGGCGCCGGCGACGGCGGACGCCGCTGACTCCGGCGAGCCAACCCCCTGCCCGGCGCCGGGCAGG
GCGTACCGACGGGCGGCGTT

Product: translation elongation factor G

Products: NA

Alternate protein names: EF-G 2 [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MGEPRGEGTASERRMRAIRNLGIMAHIDAGKTTLTERLLFVAGRTHKMGEVHEGAAVMDWMDLERERGITITSAVTRLEW
RAHELHLIDTPGHVDFTIEVERSLRVLDGAVAVFDAAHGVEPQSETVWRQADRYHVPRIAFANKMDRVGADLGHTLASMR
KHFPDHVVAAVQRPLGAEAAFSGFEDLVARRTVRFGDPDDPRAFTAEPGISAEGEAERAALVAALADLDDAAAEAVLSDR
DLDEEGLRSAIRRATLSGRFVPLLCGSALRNKGIPQVLDAVCDWLPSPLDVPPPAGVHPDTGEEERRPPTDGAPLLALAF
KVSLLDERRRYVFLRVYSGRVAEGDAVWNASQRKFEKVGRVLLMHAAQKERVPSLGAGQLFAVAGLKETRTGDTLTDKAH
PLLLERLSSYDPVISEAIEAGSQKDRELLLEALARVADEDPTFRWGEDPDTGQLLVSGMGELHLDVVAERLRREFGLAVR
TGQPQVLLRETLSAEATADATFERKLEDEEIYGQVSVAVGPLPRGGGFRFEVSPEAAALPFLRPEVRRMAEDGAREAAEA
GALEGHPLQDVRVTLTGATWREGASKPFAYKVAAADAVRTAAAKARPVILEPLMRVEIVLPSEHLGEVIGSLDRRKGTVL
DVADRGEAVKVITCEAPLRRMFGYATELRSATQGRALFTMRFDRFDVAG

Sequences:

>Translated_689_residues
MGEPRGEGTASERRMRAIRNLGIMAHIDAGKTTLTERLLFVAGRTHKMGEVHEGAAVMDWMDLERERGITITSAVTRLEW
RAHELHLIDTPGHVDFTIEVERSLRVLDGAVAVFDAAHGVEPQSETVWRQADRYHVPRIAFANKMDRVGADLGHTLASMR
KHFPDHVVAAVQRPLGAEAAFSGFEDLVARRTVRFGDPDDPRAFTAEPGISAEGEAERAALVAALADLDDAAAEAVLSDR
DLDEEGLRSAIRRATLSGRFVPLLCGSALRNKGIPQVLDAVCDWLPSPLDVPPPAGVHPDTGEEERRPPTDGAPLLALAF
KVSLLDERRRYVFLRVYSGRVAEGDAVWNASQRKFEKVGRVLLMHAAQKERVPSLGAGQLFAVAGLKETRTGDTLTDKAH
PLLLERLSSYDPVISEAIEAGSQKDRELLLEALARVADEDPTFRWGEDPDTGQLLVSGMGELHLDVVAERLRREFGLAVR
TGQPQVLLRETLSAEATADATFERKLEDEEIYGQVSVAVGPLPRGGGFRFEVSPEAAALPFLRPEVRRMAEDGAREAAEA
GALEGHPLQDVRVTLTGATWREGASKPFAYKVAAADAVRTAAAKARPVILEPLMRVEIVLPSEHLGEVIGSLDRRKGTVL
DVADRGEAVKVITCEAPLRRMFGYATELRSATQGRALFTMRFDRFDVAG
>Mature_688_residues
GEPRGEGTASERRMRAIRNLGIMAHIDAGKTTLTERLLFVAGRTHKMGEVHEGAAVMDWMDLERERGITITSAVTRLEWR
AHELHLIDTPGHVDFTIEVERSLRVLDGAVAVFDAAHGVEPQSETVWRQADRYHVPRIAFANKMDRVGADLGHTLASMRK
HFPDHVVAAVQRPLGAEAAFSGFEDLVARRTVRFGDPDDPRAFTAEPGISAEGEAERAALVAALADLDDAAAEAVLSDRD
LDEEGLRSAIRRATLSGRFVPLLCGSALRNKGIPQVLDAVCDWLPSPLDVPPPAGVHPDTGEEERRPPTDGAPLLALAFK
VSLLDERRRYVFLRVYSGRVAEGDAVWNASQRKFEKVGRVLLMHAAQKERVPSLGAGQLFAVAGLKETRTGDTLTDKAHP
LLLERLSSYDPVISEAIEAGSQKDRELLLEALARVADEDPTFRWGEDPDTGQLLVSGMGELHLDVVAERLRREFGLAVRT
GQPQVLLRETLSAEATADATFERKLEDEEIYGQVSVAVGPLPRGGGFRFEVSPEAAALPFLRPEVRRMAEDGAREAAEAG
ALEGHPLQDVRVTLTGATWREGASKPFAYKVAAADAVRTAAAKARPVILEPLMRVEIVLPSEHLGEVIGSLDRRKGTVLD
VADRGEAVKVITCEAPLRRMFGYATELRSATQGRALFTMRFDRFDVAG

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=680, Percent_Identity=39.4117647058824, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI19923640, Length=713, Percent_Identity=37.7279102384292, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI25306287, Length=710, Percent_Identity=35.9154929577465, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI25306283, Length=391, Percent_Identity=45.0127877237852, Blast_Score=295, Evalue=1e-79,
Organism=Homo sapiens, GI157426893, Length=138, Percent_Identity=40.5797101449275, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI94966754, Length=160, Percent_Identity=34.375, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI4503483, Length=437, Percent_Identity=23.1121281464531, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310132016, Length=124, Percent_Identity=36.2903225806452, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI310110807, Length=124, Percent_Identity=36.2903225806452, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI310123363, Length=124, Percent_Identity=36.2903225806452, Blast_Score=80, Evalue=7e-15,
Organism=Escherichia coli, GI1789738, Length=685, Percent_Identity=42.7737226277372, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1790835, Length=508, Percent_Identity=26.3779527559055, Blast_Score=142, Evalue=9e-35,
Organism=Escherichia coli, GI1788922, Length=142, Percent_Identity=42.9577464788732, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI48994988, Length=136, Percent_Identity=42.6470588235294, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17533571, Length=690, Percent_Identity=36.0869565217391, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17556745, Length=700, Percent_Identity=29.5714285714286, Blast_Score=278, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17557151, Length=163, Percent_Identity=39.8773006134969, Blast_Score=106, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17506493, Length=235, Percent_Identity=33.1914893617021, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988819, Length=162, Percent_Identity=31.4814814814815, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988811, Length=162, Percent_Identity=31.4814814814815, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323098, Length=686, Percent_Identity=37.7551020408163, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6322359, Length=792, Percent_Identity=28.1565656565657, Blast_Score=306, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6324707, Length=799, Percent_Identity=25.531914893617, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320593, Length=799, Percent_Identity=25.531914893617, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323320, Length=166, Percent_Identity=34.3373493975904, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=193, Percent_Identity=32.6424870466321, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582462, Length=681, Percent_Identity=38.913362701909, Blast_Score=447, Evalue=1e-125,
Organism=Drosophila melanogaster, GI221458488, Length=704, Percent_Identity=32.8125, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI78706572, Length=158, Percent_Identity=39.2405063291139, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585709, Length=435, Percent_Identity=24.1379310344828, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24585711, Length=435, Percent_Identity=24.1379310344828, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585713, Length=435, Percent_Identity=24.1379310344828, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28574573, Length=149, Percent_Identity=35.5704697986577, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21357743, Length=142, Percent_Identity=31.6901408450704, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 75249; Mature: 75118

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEPRGEGTASERRMRAIRNLGIMAHIDAGKTTLTERLLFVAGRTHKMGEVHEGAAVMDW
CCCCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHCCCHHHHH
MDLERERGITITSAVTRLEWRAHELHLIDTPGHVDFTIEVERSLRVLDGAVAVFDAAHGV
HHHHHHCCCCHHHHHHHHHHEEEEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHCCC
EPQSETVWRQADRYHVPRIAFANKMDRVGADLGHTLASMRKHFPDHVVAAVQRPLGAEAA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHH
FSGFEDLVARRTVRFGDPDDPRAFTAEPGISAEGEAERAALVAALADLDDAAAEAVLSDR
HCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DLDEEGLRSAIRRATLSGRFVPLLCGSALRNKGIPQVLDAVCDWLPSPLDVPPPAGVHPD
CCCHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
TGEEERRPPTDGAPLLALAFKVSLLDERRRYVFLRVYSGRVAEGDAVWNASQRKFEKVGR
CCCHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEECCCHHCCHHHHHHHHHHH
VLLMHAAQKERVPSLGAGQLFAVAGLKETRTGDTLTDKAHPLLLERLSSYDPVISEAIEA
HHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHC
GSQKDRELLLEALARVADEDPTFRWGEDPDTGQLLVSGMGELHLDVVAERLRREFGLAVR
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEEE
TGQPQVLLRETLSAEATADATFERKLEDEEIYGQVSVAVGPLPRGGGFRFEVSPEAAALP
CCCCHHHHHHHHCCCCCCCHHHHHHCCCHHHHEEEEEEECCCCCCCCEEEEECCCHHCCC
FLRPEVRRMAEDGAREAAEAGALEGHPLQDVRVTLTGATWREGASKPFAYKVAAADAVRT
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHCCCCCCCEEEEHHHHHHHH
AAAKARPVILEPLMRVEIVLPSEHLGEVIGSLDRRKGTVLDVADRGEAVKVITCEAPLRR
HHHHCCCHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCHHHHH
MFGYATELRSATQGRALFTMRFDRFDVAG
HHHHHHHHHHHCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
GEPRGEGTASERRMRAIRNLGIMAHIDAGKTTLTERLLFVAGRTHKMGEVHEGAAVMDW
CCCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCCHHCCCHHHHH
MDLERERGITITSAVTRLEWRAHELHLIDTPGHVDFTIEVERSLRVLDGAVAVFDAAHGV
HHHHHHCCCCHHHHHHHHHHEEEEEEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHCCC
EPQSETVWRQADRYHVPRIAFANKMDRVGADLGHTLASMRKHFPDHVVAAVQRPLGAEAA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHH
FSGFEDLVARRTVRFGDPDDPRAFTAEPGISAEGEAERAALVAALADLDDAAAEAVLSDR
HCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DLDEEGLRSAIRRATLSGRFVPLLCGSALRNKGIPQVLDAVCDWLPSPLDVPPPAGVHPD
CCCHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
TGEEERRPPTDGAPLLALAFKVSLLDERRRYVFLRVYSGRVAEGDAVWNASQRKFEKVGR
CCCHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEECCCHHCCHHHHHHHHHHH
VLLMHAAQKERVPSLGAGQLFAVAGLKETRTGDTLTDKAHPLLLERLSSYDPVISEAIEA
HHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHC
GSQKDRELLLEALARVADEDPTFRWGEDPDTGQLLVSGMGELHLDVVAERLRREFGLAVR
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEEE
TGQPQVLLRETLSAEATADATFERKLEDEEIYGQVSVAVGPLPRGGGFRFEVSPEAAALP
CCCCHHHHHHHHCCCCCCCHHHHHHCCCHHHHEEEEEEECCCCCCCCEEEEECCCHHCCC
FLRPEVRRMAEDGAREAAEAGALEGHPLQDVRVTLTGATWREGASKPFAYKVAAADAVRT
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHCCCCCCCEEEEHHHHHHHH
AAAKARPVILEPLMRVEIVLPSEHLGEVIGSLDRRKGTVLDVADRGEAVKVITCEAPLRR
HHHHCCCHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCHHHHH
MFGYATELRSATQGRALFTMRFDRFDVAG
HHHHHHHHHHHCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA