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The map label for this gene is panE [C]

Identifier: 220916894

GI number: 220916894

Start: 2000214

End: 2001212

Strand: Reverse

Name: panE [C]

Synonym: A2cp1_1790

Alternate gene names: 220916894

Gene position: 2001212-2000214 (Counterclockwise)

Preceding gene: 220916896

Following gene: 220916893

Centisome position: 39.79

GC content: 74.57

Gene sequence:

>999_bases
GTGCTGCGCTTCCGTGCGGGTTGCGCCGCGCGGGCCGCGCTCCGCGGTTACGATGCACGCATGCGGAGCATCGAGAGCGT
GGTGGTGTGCGGCGTGGGGGCGGTGGGCGCGGCCGCGGTCGAGCGGCTGCACGCCATGGATCCAGCGTGCGTGACGGTGG
TGGCGGACGGCGCGCGCCGCGAGCGCCTGGAGCGCGAGGGGCTCACCGTCAACGGCCGACGGTTCTCGCCGCGCGTGGCC
GCGCCGTCGGCGCTGACCCCGGCGGATCTCCTCCTCGTCGGCGTGAAGCACGGCGACCTCACGGCCGCGGTCGAGGATGC
CCGCCGCGCGGTCGGTCCGCGCACGGTCGTCATGTCGCTGCTGAACGGGATCTCCAGCGAGGCGACGCTCGCCGAGGCGT
ACGGCGCCGACAAGGTGCTCCCGGCGTTCCTCGTCGGCAACGACGTGGTGCGCGAGGGGACGCACGTCCGCTACCAGAAC
ATCGGCCGGCTGGTGTTCGGCGCGCCCTCGAACGACCCGGCCGACCCGCGCGTCCTCACGGTGAAGCACCTCCTCGACCG
GGCCGGCATCCCGTGCCAGGTCGCCGCGGACATCCGGCGCGAGCAGTGGTGGAAGTTCATGCTGAACGTGGGCGTGAACC
AGGTCTCGGCGCTGCTGCGCGCGCCCTACGGCGCGTTCATGCTCGAGGAGGTCCGCGCGCTCGCCCGCCGGGCGGCGCTC
GAGGTGGTCGCGGTCTCGCGGCACGAGGGCGTGGGGCTGGTGGCCGAGGACGTGGAGCGGATCTTCCCGGTCATTGCCGG
GCTCGCGCCCGCGGGGAAGACGTCGATGCTGCAGGACGTGGAGGCGGGCCGGAAGACGGAGGTGGAGATCTTCGCGGGTG
CGGTGGTCGAGCTCGGCCGCCGGCACGCGGTCGCGACCCCCACGAACGCATTCCTGGGCCAGGCCATCGCGGCGCTCGAC
GCGATCGCGGCCGCGCGCGGGGCCGGGGGCGTCGCATGA

Upstream 100 bases:

>100_bases
CCCGCGCGCCCAGCGCCTGCGTGATCGGGATGTGCGCGTGCAGGTACTCGGTGATCTCGTCGTGGCGCATGCCGGGTTGG
ATACCGCGGGAGGCGGCGAG

Downstream 100 bases:

>100_bases
CCGCGGGTCCCGGGCTCGTCGGCCTGCAGGTCCGGCCCGGCCACCCGGACTTCCTCGACCTGCCATGGGATCTCCCGCTC
TCCCGCTGGGGCGAGCGCTG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLRFRAGCAARAALRGYDARMRSIESVVVCGVGAVGAAAVERLHAMDPACVTVVADGARRERLEREGLTVNGRRFSPRVA
APSALTPADLLLVGVKHGDLTAAVEDARRAVGPRTVVMSLLNGISSEATLAEAYGADKVLPAFLVGNDVVREGTHVRYQN
IGRLVFGAPSNDPADPRVLTVKHLLDRAGIPCQVAADIRREQWWKFMLNVGVNQVSALLRAPYGAFMLEEVRALARRAAL
EVVAVSRHEGVGLVAEDVERIFPVIAGLAPAGKTSMLQDVEAGRKTEVEIFAGAVVELGRRHAVATPTNAFLGQAIAALD
AIAAARGAGGVA

Sequences:

>Translated_332_residues
MLRFRAGCAARAALRGYDARMRSIESVVVCGVGAVGAAAVERLHAMDPACVTVVADGARRERLEREGLTVNGRRFSPRVA
APSALTPADLLLVGVKHGDLTAAVEDARRAVGPRTVVMSLLNGISSEATLAEAYGADKVLPAFLVGNDVVREGTHVRYQN
IGRLVFGAPSNDPADPRVLTVKHLLDRAGIPCQVAADIRREQWWKFMLNVGVNQVSALLRAPYGAFMLEEVRALARRAAL
EVVAVSRHEGVGLVAEDVERIFPVIAGLAPAGKTSMLQDVEAGRKTEVEIFAGAVVELGRRHAVATPTNAFLGQAIAALD
AIAAARGAGGVA
>Mature_332_residues
MLRFRAGCAARAALRGYDARMRSIESVVVCGVGAVGAAAVERLHAMDPACVTVVADGARRERLEREGLTVNGRRFSPRVA
APSALTPADLLLVGVKHGDLTAAVEDARRAVGPRTVVMSLLNGISSEATLAEAYGADKVLPAFLVGNDVVREGTHVRYQN
IGRLVFGAPSNDPADPRVLTVKHLLDRAGIPCQVAADIRREQWWKFMLNVGVNQVSALLRAPYGAFMLEEVRALARRAAL
EVVAVSRHEGVGLVAEDVERIFPVIAGLAPAGKTSMLQDVEAGRKTEVEIFAGAVVELGRRHAVATPTNAFLGQAIAALD
AIAAARGAGGVA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34987; Mature: 34987

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFRAGCAARAALRGYDARMRSIESVVVCGVGAVGAAAVERLHAMDPACVTVVADGARR
CCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHH
ERLEREGLTVNGRRFSPRVAAPSALTPADLLLVGVKHGDLTAAVEDARRAVGPRTVVMSL
HHHHHCCCEECCCCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHCCHHHHHHHH
LNGISSEATLAEAYGADKVLPAFLVGNDVVREGTHVRYQNIGRLVFGAPSNDPADPRVLT
HHCCCCCHHHHHHCCCCHHHHHHHHCCHHHHCCCCEEHHCCCEEEEECCCCCCCCCCEEH
VKHLLDRAGIPCQVAADIRREQWWKFMLNVGVNQVSALLRAPYGAFMLEEVRALARRAAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVVAVSRHEGVGLVAEDVERIFPVIAGLAPAGKTSMLQDVEAGRKTEVEIFAGAVVELGR
HHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHC
RHAVATPTNAFLGQAIAALDAIAAARGAGGVA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLRFRAGCAARAALRGYDARMRSIESVVVCGVGAVGAAAVERLHAMDPACVTVVADGARR
CCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHH
ERLEREGLTVNGRRFSPRVAAPSALTPADLLLVGVKHGDLTAAVEDARRAVGPRTVVMSL
HHHHHCCCEECCCCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHCCHHHHHHHH
LNGISSEATLAEAYGADKVLPAFLVGNDVVREGTHVRYQNIGRLVFGAPSNDPADPRVLT
HHCCCCCHHHHHHCCCCHHHHHHHHCCHHHHCCCCEEHHCCCEEEEECCCCCCCCCCEEH
VKHLLDRAGIPCQVAADIRREQWWKFMLNVGVNQVSALLRAPYGAFMLEEVRALARRAAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVVAVSRHEGVGLVAEDVERIFPVIAGLAPAGKTSMLQDVEAGRKTEVEIFAGAVVELGR
HHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHC
RHAVATPTNAFLGQAIAALDAIAAARGAGGVA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]