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The map label for this gene is mrdB [H]

Identifier: 220916561

GI number: 220916561

Start: 1629491

End: 1630612

Strand: Direct

Name: mrdB [H]

Synonym: A2cp1_1455

Alternate gene names: 220916561

Gene position: 1629491-1630612 (Clockwise)

Preceding gene: 220916560

Following gene: 220916563

Centisome position: 32.4

GC content: 69.07

Gene sequence:

>1122_bases
GTGGCGCCTGACGTCTCGCTCGCGGCCACGCCGCACCGGCGCGTGTTCGCGCACTTCCCCTGGCACCTCGCGCTGATCGT
CCTGTCGATCTCGGCGATCGGGATCTGGAACCTCTCCTCCGCCTCGCGCAGCGCGCACGCGCCGGTCTGGATCTCGCAGA
CCTGGTGGATGGGCGCCGGCGCGGTGCTGGCGCTCGCCATCACGCTGGTGGACCACCGCGCGTTCCACCGCATGGCCTGG
GTGTTCTACGCGGTGGTGCTGGTGCTGCTCGTGCTGGTGATGGTGAAGGGGCGCTACGTCATGGGCGCCCGGCGCTGGTT
GACCATCGGCCCGGTGAACTTCCAGCCCTCCGAGCTGGCGAAGCTCTCGGTGGCGCTCGCGCTGGCGAGCTTCTTCGCGT
CGGACACCGAGAAGCGCAAGGACGGCTACGGGCTGCTGCGCCTGATCGCGCCGATGCTGATCGCGCTCGTCCCGGCGGTG
CTCATCCTGAAGCAGCCGGACCTGGGCACCGCGCTCATCGTGCTGTCGGTCGGGTTCACCCAGATCCTGTTCGCGAAGGT
GCGCTGGAAGACGCTGGCGCTGCTGGCGGGCGTGGCGGTGGTCGGGTCGGTGCTCGTCTACCCGCACCTGAAGCCGTACC
AGAAGAAGCGCGTCGAGACGTTCATCAACCCGGAGGCGGACGCGCTCGGCGCGGGCTACCACGCCACCCAGTCGATGATC
GCGGTGGGCTCGGGGCAGGGGCTGGGGAAGGGCTGGGGGCAGGGCACCCAGACGTACCTGTCGTTCCTCCCCGAGCAGCA
CACCGACTTCATCTTCTCGGTGTGGGCCGAGGAGCACGGGTTCGTCGGCTGCCTGCTGCTGATCGCGCTCTACTTCGCGC
TGGTGACGAGCGCCATGGACGTCGCGGGCAACGCGCGCGACCGGTTCGGGCACTTCCTGGCGGTGGGGCTCACCGGGATG
CTCTTCTGGCACGTCGCCATCAACATCGGGATGGTGATCGGCCTGCTGCCGGTGGTGGGGGTGACGCTCCCGCTGATGAG
CTACGGCGGGTCGAGCGTGATCGTCATCTACAGCGGGATCGGCCTGCTCGCGAACGTCGGGATGCGCCGGTTCGTGAACT
GA

Upstream 100 bases:

>100_bases
GCGCCTCCCGCCGCGCCGCCCGCGGCGCCGCCGCCCGGCGCGGTCGAGCCGGCCAGGCTGGGCACGGGCGGCGCGTCCGC
CGCGGTGCCGGGGGTGGACC

Downstream 100 bases:

>100_bases
GGGTGACGCGTGCCGCGCGCGCGTCGAGCGGTCGACGCGGCACGTTGCCGCACCTCGCGCCCCCGCCCGCCCGCGGCCCG
CCGTGGCGGCCGCGAGCGGG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MAPDVSLAATPHRRVFAHFPWHLALIVLSISAIGIWNLSSASRSAHAPVWISQTWWMGAGAVLALAITLVDHRAFHRMAW
VFYAVVLVLLVLVMVKGRYVMGARRWLTIGPVNFQPSELAKLSVALALASFFASDTEKRKDGYGLLRLIAPMLIALVPAV
LILKQPDLGTALIVLSVGFTQILFAKVRWKTLALLAGVAVVGSVLVYPHLKPYQKKRVETFINPEADALGAGYHATQSMI
AVGSGQGLGKGWGQGTQTYLSFLPEQHTDFIFSVWAEEHGFVGCLLLIALYFALVTSAMDVAGNARDRFGHFLAVGLTGM
LFWHVAINIGMVIGLLPVVGVTLPLMSYGGSSVIVIYSGIGLLANVGMRRFVN

Sequences:

>Translated_373_residues
MAPDVSLAATPHRRVFAHFPWHLALIVLSISAIGIWNLSSASRSAHAPVWISQTWWMGAGAVLALAITLVDHRAFHRMAW
VFYAVVLVLLVLVMVKGRYVMGARRWLTIGPVNFQPSELAKLSVALALASFFASDTEKRKDGYGLLRLIAPMLIALVPAV
LILKQPDLGTALIVLSVGFTQILFAKVRWKTLALLAGVAVVGSVLVYPHLKPYQKKRVETFINPEADALGAGYHATQSMI
AVGSGQGLGKGWGQGTQTYLSFLPEQHTDFIFSVWAEEHGFVGCLLLIALYFALVTSAMDVAGNARDRFGHFLAVGLTGM
LFWHVAINIGMVIGLLPVVGVTLPLMSYGGSSVIVIYSGIGLLANVGMRRFVN
>Mature_372_residues
APDVSLAATPHRRVFAHFPWHLALIVLSISAIGIWNLSSASRSAHAPVWISQTWWMGAGAVLALAITLVDHRAFHRMAWV
FYAVVLVLLVLVMVKGRYVMGARRWLTIGPVNFQPSELAKLSVALALASFFASDTEKRKDGYGLLRLIAPMLIALVPAVL
ILKQPDLGTALIVLSVGFTQILFAKVRWKTLALLAGVAVVGSVLVYPHLKPYQKKRVETFINPEADALGAGYHATQSMIA
VGSGQGLGKGWGQGTQTYLSFLPEQHTDFIFSVWAEEHGFVGCLLLIALYFALVTSAMDVAGNARDRFGHFLAVGLTGML
FWHVAINIGMVIGLLPVVGVTLPLMSYGGSSVIVIYSGIGLLANVGMRRFVN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=319, Percent_Identity=42.6332288401254, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786277, Length=356, Percent_Identity=33.9887640449438, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40372; Mature: 40241

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPDVSLAATPHRRVFAHFPWHLALIVLSISAIGIWNLSSASRSAHAPVWISQTWWMGAG
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCEECCCCCCCCCCCCEEEECCHHCCHH
AVLALAITLVDHRAFHRMAWVFYAVVLVLLVLVMVKGRYVMGARRWLTIGPVNFQPSELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCCCHHHHH
KLSVALALASFFASDTEKRKDGYGLLRLIAPMLIALVPAVLILKQPDLGTALIVLSVGFT
HHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QILFAKVRWKTLALLAGVAVVGSVLVYPHLKPYQKKRVETFINPEADALGAGYHATQSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHCCCCHHHHHHHH
AVGSGQGLGKGWGQGTQTYLSFLPEQHTDFIFSVWAEEHGFVGCLLLIALYFALVTSAMD
EECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VAGNARDRFGHFLAVGLTGMLFWHVAINIGMVIGLLPVVGVTLPLMSYGGSSVIVIYSGI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECH
GLLANVGMRRFVN
HHHHHHHHHHHCC
>Mature Secondary Structure 
APDVSLAATPHRRVFAHFPWHLALIVLSISAIGIWNLSSASRSAHAPVWISQTWWMGAG
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCEECCCCCCCCCCCCEEEECCHHCCHH
AVLALAITLVDHRAFHRMAWVFYAVVLVLLVLVMVKGRYVMGARRWLTIGPVNFQPSELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCCCHHHHH
KLSVALALASFFASDTEKRKDGYGLLRLIAPMLIALVPAVLILKQPDLGTALIVLSVGFT
HHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QILFAKVRWKTLALLAGVAVVGSVLVYPHLKPYQKKRVETFINPEADALGAGYHATQSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHCCCCHHHHHHHH
AVGSGQGLGKGWGQGTQTYLSFLPEQHTDFIFSVWAEEHGFVGCLLLIALYFALVTSAMD
EECCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VAGNARDRFGHFLAVGLTGMLFWHVAINIGMVIGLLPVVGVTLPLMSYGGSSVIVIYSGI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECH
GLLANVGMRRFVN
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]