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The map label for this gene is nuoI1 [H]

Identifier: 220916491

GI number: 220916491

Start: 1550242

End: 1550961

Strand: Direct

Name: nuoI1 [H]

Synonym: A2cp1_1385

Alternate gene names: 220916491

Gene position: 1550242-1550961 (Clockwise)

Preceding gene: 220916490

Following gene: 220916492

Centisome position: 30.82

GC content: 70.83

Gene sequence:

>720_bases
ATGCCCTACCAGCTCGAGAACCGCCCGCCGGACCTGCGCGAGTCGATGTACTTCCCGGAGATCATCCGGGGCATCGGCAC
GATCACGAAGCACTTCCTGAAGAACCTGTTCTTCTCGCGCGACGCGAACCCGGACATCCTCGCCCGCAAGCGCGGGGGCT
TCGGGCACTCGGACAACGTCACGCTGCAGTACCCGGAGGAGCGGGCGCCCTACGCGCCGGCCTACCGCGGGCTGCACCGG
CTGGTGCCGCGCGAGGACGGGAAGCCGCGCTGCGTCGCCTGCTACATGTGCGCGACGATCTGCCCGGCGCAGTGCATCTA
CATCGAGGCCGCCGAGTACCCGGACGATCCGGTCGAGAAGTACCCCGCGAAGTTCGTGATCGACGAGCTGCGCTGCATCG
TGTGCGGCTTCTGCGTGGAGGCCTGCCCGAAGGACGCCATCCGCATGGACTCCGGCGAGCACACGCCGCCGTCCTACGAG
CGCTCGGCGCAGATCTGGGACGAGAAGCGGCTGCTCCGCGGGCCGCCGGTGTCGTACCAGTACGACCCGTGGCTGCGCCG
CGGCTCGCCGTCCATCCCGCCCGACAAGCTCGAGGAGATGCGCGCCCGCGCGAAGCCGTTCCCGACGGTGGCGACCGACG
AGGCCAGCCAGACGCCGGGGTTCTCGGTGCGGGCGCTCGCGGCCGAGGCCAGGGACCGGGCGCAGGCGGCCCGCAAGTAG

Upstream 100 bases:

>100_bases
ACCATCGTCGTCATCGCCGTCCTCACCGCCGCGGTCGGCCGCGCGCCCGCCCCCGCGGCGGGACACGGCGCCGCCCACGC
CGCCGCCGGACACTGACGCC

Downstream 100 bases:

>100_bases
GTCCGGTCCGGCCGTCCCGAGGCCCCGCCCGCCGGCTCCGGCGGCGGGGCCTCCGTGCGTCCGGGAGGGAGGCGCCTTGA
CGCGGGCGATCACCAGGGCG

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I 1; NDH-1 subunit I 1 [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MPYQLENRPPDLRESMYFPEIIRGIGTITKHFLKNLFFSRDANPDILARKRGGFGHSDNVTLQYPEERAPYAPAYRGLHR
LVPREDGKPRCVACYMCATICPAQCIYIEAAEYPDDPVEKYPAKFVIDELRCIVCGFCVEACPKDAIRMDSGEHTPPSYE
RSAQIWDEKRLLRGPPVSYQYDPWLRRGSPSIPPDKLEEMRARAKPFPTVATDEASQTPGFSVRALAAEARDRAQAARK

Sequences:

>Translated_239_residues
MPYQLENRPPDLRESMYFPEIIRGIGTITKHFLKNLFFSRDANPDILARKRGGFGHSDNVTLQYPEERAPYAPAYRGLHR
LVPREDGKPRCVACYMCATICPAQCIYIEAAEYPDDPVEKYPAKFVIDELRCIVCGFCVEACPKDAIRMDSGEHTPPSYE
RSAQIWDEKRLLRGPPVSYQYDPWLRRGSPSIPPDKLEEMRARAKPFPTVATDEASQTPGFSVRALAAEARDRAQAARK
>Mature_238_residues
PYQLENRPPDLRESMYFPEIIRGIGTITKHFLKNLFFSRDANPDILARKRGGFGHSDNVTLQYPEERAPYAPAYRGLHRL
VPREDGKPRCVACYMCATICPAQCIYIEAAEYPDDPVEKYPAKFVIDELRCIVCGFCVEACPKDAIRMDSGEHTPPSYER
SAQIWDEKRLLRGPPVSYQYDPWLRRGSPSIPPDKLEEMRARAKPFPTVATDEASQTPGFSVRALAAEARDRAQAARK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=183, Percent_Identity=30.0546448087432, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1788617, Length=147, Percent_Identity=36.734693877551, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555194, Length=166, Percent_Identity=32.5301204819277, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17864306, Length=183, Percent_Identity=31.6939890710383, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 27168; Mature: 27037

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYQLENRPPDLRESMYFPEIIRGIGTITKHFLKNLFFSRDANPDILARKRGGFGHSDNV
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCE
TLQYPEERAPYAPAYRGLHRLVPREDGKPRCVACYMCATICPAQCIYIEAAEYPDDPVEK
EEECCHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
YPAKFVIDELRCIVCGFCVEACPKDAIRMDSGEHTPPSYERSAQIWDEKRLLRGPPVSYQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
YDPWLRRGSPSIPPDKLEEMRARAKPFPTVATDEASQTPGFSVRALAAEARDRAQAARK
CCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PYQLENRPPDLRESMYFPEIIRGIGTITKHFLKNLFFSRDANPDILARKRGGFGHSDNV
CCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCE
TLQYPEERAPYAPAYRGLHRLVPREDGKPRCVACYMCATICPAQCIYIEAAEYPDDPVEK
EEECCHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
YPAKFVIDELRCIVCGFCVEACPKDAIRMDSGEHTPPSYERSAQIWDEKRLLRGPPVSYQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
YDPWLRRGSPSIPPDKLEEMRARAKPFPTVATDEASQTPGFSVRALAAEARDRAQAARK
CCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA