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The map label for this gene is nuoH1 [H]

Identifier: 220916490

GI number: 220916490

Start: 1548855

End: 1550237

Strand: Direct

Name: nuoH1 [H]

Synonym: A2cp1_1384

Alternate gene names: 220916490

Gene position: 1548855-1550237 (Clockwise)

Preceding gene: 220916489

Following gene: 220916491

Centisome position: 30.8

GC content: 70.43

Gene sequence:

>1383_bases
GTGAACCGATTCTTCGGAATGCTCCTCGTCATCGCGGCGACGCTGGCCGGCCTGGTCGTCCTGTCGGCCGGGTTCTACCT
GGCCGCCGGCTGGCTGGGCTGGGGCTTCAACGCCCTGGCCGGCTGGATCACCGGCTCGCCGGGCGTCTCCCGCGCGGCCG
TGTACTACGGCGCCTCCGTGGCGAACGTGCTGACGCTGCTGCTGGTCGTGCTGATGATCAGCTCGTCGCTGCTCACGGTG
GCCGAGCGCAAGTGGTCGGCGCTCATCCAGAACCGCATCGGCGCGAACCGCATCAAGGTGTTCGGCTCGGCGCTGGGCGG
CATCCCGTTCCTCGCCGCCGACGCGCTCAAGATGCTCACCAAGGAGCGCATCGAGACCACCGGGCGCACCCGGGTGCTCT
ACGAGCTCGCGCCCATGCTGGCGTTCGCGCCGGTGTTCGCGCTGTTCGCGATCATCCCGGTGGGGCAGGGGATCGAGCTG
AACCAGATCCCGGGCCTGGCGGGCGCGGCCGCGTCGGGCGCGGTCGAGCAGATCGCGCTGCAGGTCTCGCGCACCGACAC
CGGCCTGCTGTACCTGTTCGCGATCGCCTCGCTCCAGGTGTACGGCACCGCGCTCGCGGGCTGGGCCTCGAACAACAAGC
TGGCGCTGCTCGGCGGCGTCCGCGCCTCCTCGCAGATGATCAGCTACGAGGTGTCGCTGGGCCTGTCGCTGGTCGGCACG
ATGATCGCGTTCCGGACGCTCCGCCTGGAGGAGATGGTGGTGGCGCAGGGGAACCCGGTGCTCGGCCCGGTGCCGGCGCT
GGGCCTGCTCCTGCAGCCCATCGGCTTCCTCATCTTCTTCGCCAGCGCGTTCGCCGAGACCAAGCGCGCGCCGTTCGACC
TCCCCGAGGGCGAGAGCGAGATCGTCGGCTACTTCGTCGAGTACTCCGGCATGAAGTTCGGCCTGCTGTTCCTGGCCGAG
TTCGCCGAGATCGTGGTGCTCGCGGGCGTGATCACCGCCGTGTTCCTGGGCGGCTGGCACCCCATCCTGTTCGAGGGCTG
GCTGCGCCAGAACCTGACGCCGTTCTGGTTCGCGGCGGTCGGCGCCGGGGCGTTCATCGCCAAGATGATCGTCATGATGT
GGCTGCAGCTCACCATCCGCTGGCTGCTGCCGCGCTTCCGCTTCGACCAGATCCAGAAGCTGTGCTGGAAGCTGCTGCTC
CCGGCCGCCCTGGTGAACGTCTTCGTGACCGGCGGCGCGCTGCTGCTCGACCCGAGCGGCCAGCTGCTGGCCTGGATCGG
CGTCCTCACCATCGTCGTCATCGCCGTCCTCACCGCCGCGGTCGGCCGCGCGCCCGCCCCCGCGGCGGGACACGGCGCCG
CCCACGCCGCCGCCGGACACTGA

Upstream 100 bases:

>100_bases
CGTCGATGGCCGCCTGCCGGGCAACCGCGACCGCGTGCCGTCCGAGACCACCGAGGATTACCGCCGCGCGATGTCGCGCA
CGTCGTAGGAGGGAGAGCCG

Downstream 100 bases:

>100_bases
CGCCATGCCCTACCAGCTCGAGAACCGCCCGCCGGACCTGCGCGAGTCGATGTACTTCCCGGAGATCATCCGGGGCATCG
GCACGATCACGAAGCACTTC

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNRFFGMLLVIAATLAGLVVLSAGFYLAAGWLGWGFNALAGWITGSPGVSRAAVYYGASVANVLTLLLVVLMISSSLLTV
AERKWSALIQNRIGANRIKVFGSALGGIPFLAADALKMLTKERIETTGRTRVLYELAPMLAFAPVFALFAIIPVGQGIEL
NQIPGLAGAAASGAVEQIALQVSRTDTGLLYLFAIASLQVYGTALAGWASNNKLALLGGVRASSQMISYEVSLGLSLVGT
MIAFRTLRLEEMVVAQGNPVLGPVPALGLLLQPIGFLIFFASAFAETKRAPFDLPEGESEIVGYFVEYSGMKFGLLFLAE
FAEIVVLAGVITAVFLGGWHPILFEGWLRQNLTPFWFAAVGAGAFIAKMIVMMWLQLTIRWLLPRFRFDQIQKLCWKLLL
PAALVNVFVTGGALLLDPSGQLLAWIGVLTIVVIAVLTAAVGRAPAPAAGHGAAHAAAGH

Sequences:

>Translated_460_residues
MNRFFGMLLVIAATLAGLVVLSAGFYLAAGWLGWGFNALAGWITGSPGVSRAAVYYGASVANVLTLLLVVLMISSSLLTV
AERKWSALIQNRIGANRIKVFGSALGGIPFLAADALKMLTKERIETTGRTRVLYELAPMLAFAPVFALFAIIPVGQGIEL
NQIPGLAGAAASGAVEQIALQVSRTDTGLLYLFAIASLQVYGTALAGWASNNKLALLGGVRASSQMISYEVSLGLSLVGT
MIAFRTLRLEEMVVAQGNPVLGPVPALGLLLQPIGFLIFFASAFAETKRAPFDLPEGESEIVGYFVEYSGMKFGLLFLAE
FAEIVVLAGVITAVFLGGWHPILFEGWLRQNLTPFWFAAVGAGAFIAKMIVMMWLQLTIRWLLPRFRFDQIQKLCWKLLL
PAALVNVFVTGGALLLDPSGQLLAWIGVLTIVVIAVLTAAVGRAPAPAAGHGAAHAAAGH
>Mature_460_residues
MNRFFGMLLVIAATLAGLVVLSAGFYLAAGWLGWGFNALAGWITGSPGVSRAAVYYGASVANVLTLLLVVLMISSSLLTV
AERKWSALIQNRIGANRIKVFGSALGGIPFLAADALKMLTKERIETTGRTRVLYELAPMLAFAPVFALFAIIPVGQGIEL
NQIPGLAGAAASGAVEQIALQVSRTDTGLLYLFAIASLQVYGTALAGWASNNKLALLGGVRASSQMISYEVSLGLSLVGT
MIAFRTLRLEEMVVAQGNPVLGPVPALGLLLQPIGFLIFFASAFAETKRAPFDLPEGESEIVGYFVEYSGMKFGLLFLAE
FAEIVVLAGVITAVFLGGWHPILFEGWLRQNLTPFWFAAVGAGAFIAKMIVMMWLQLTIRWLLPRFRFDQIQKLCWKLLL
PAALVNVFVTGGALLLDPSGQLLAWIGVLTIVVIAVLTAAVGRAPAPAAGHGAAHAAAGH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=331, Percent_Identity=32.9305135951662, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1788618, Length=352, Percent_Identity=36.3636363636364, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 48746; Mature: 48746

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFFGMLLVIAATLAGLVVLSAGFYLAAGWLGWGFNALAGWITGSPGVSRAAVYYGASV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHCHHH
ANVLTLLLVVLMISSSLLTVAERKWSALIQNRIGANRIKVFGSALGGIPFLAADALKMLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
KERIETTGRTRVLYELAPMLAFAPVFALFAIIPVGQGIELNQIPGLAGAAASGAVEQIAL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHH
QVSRTDTGLLYLFAIASLQVYGTALAGWASNNKLALLGGVRASSQMISYEVSLGLSLVGT
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
MIAFRTLRLEEMVVAQGNPVLGPVPALGLLLQPIGFLIFFASAFAETKRAPFDLPEGESE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
IVGYFVEYSGMKFGLLFLAEFAEIVVLAGVITAVFLGGWHPILFEGWLRQNLTPFWFAAV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
GAGAFIAKMIVMMWLQLTIRWLLPRFRFDQIQKLCWKLLLPAALVNVFVTGGALLLDPSG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
QLLAWIGVLTIVVIAVLTAAVGRAPAPAAGHGAAHAAAGH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRFFGMLLVIAATLAGLVVLSAGFYLAAGWLGWGFNALAGWITGSPGVSRAAVYYGASV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHCHHH
ANVLTLLLVVLMISSSLLTVAERKWSALIQNRIGANRIKVFGSALGGIPFLAADALKMLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
KERIETTGRTRVLYELAPMLAFAPVFALFAIIPVGQGIELNQIPGLAGAAASGAVEQIAL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHH
QVSRTDTGLLYLFAIASLQVYGTALAGWASNNKLALLGGVRASSQMISYEVSLGLSLVGT
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
MIAFRTLRLEEMVVAQGNPVLGPVPALGLLLQPIGFLIFFASAFAETKRAPFDLPEGESE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
IVGYFVEYSGMKFGLLFLAEFAEIVVLAGVITAVFLGGWHPILFEGWLRQNLTPFWFAAV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
GAGAFIAKMIVMMWLQLTIRWLLPRFRFDQIQKLCWKLLLPAALVNVFVTGGALLLDPSG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
QLLAWIGVLTIVVIAVLTAAVGRAPAPAAGHGAAHAAAGH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA