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The map label for this gene is nuoG [H]

Identifier: 220916489

GI number: 220916489

Start: 1547091

End: 1548842

Strand: Direct

Name: nuoG [H]

Synonym: A2cp1_1383

Alternate gene names: 220916489

Gene position: 1547091-1548842 (Clockwise)

Preceding gene: 220916488

Following gene: 220916490

Centisome position: 30.76

GC content: 72.66

Gene sequence:

>1752_bases
ATGGCCGAAGAGAAGAAGCCCGACGCCGCGCCGCCCAAGCCGCCCGGCCCCCCGGCCCCGCCGCCGCCGAAGAACCCCGG
GTTCGTCACCGCGATCGTGGACGGGAAGGAAGTCGTGGTGAAGCCCGGCACGACCGTCATCGAGGCGGCGAAGGCGGTCG
GGATCGACATCCCGTACTACTGCTACCACAAGCGCCTCAGCATCGCGGCGAACTGCCGGATGTGCCTGGTGGAGATGTCG
AACGCGCCCGGCGGCAAGCTGATGCCGGCCTGCCAGATGCCGGTGGCCGAGGGCGTGACGGTGAAGACCGACACGCCGCG
CGTGAAGGACCAGCAGCGCGCCACGCTCGAGTTCCTGCTGCTCAACCACCCGGTCGACTGCTCCATCTGCGACCAGGCCG
GCGAGTGCAAGCTGCAGGACTACTACATGGCCTACGACCGGCAGCCCTCGCGGCTGGACGTGCCGAAGGTCGTGAAGGGC
AAGCGCGTCGAGCTCGGGCCCACCGTGACCCTGGACCAGGAGCGCTGCATCCTCTGCACGCGCTGCGTCCGGTTCATGCG
CGAGGTGGCCGAGAACCCGCAGCTCGGCGTCGCCCAGCGCGGCAACGAGAGCTTCATCACCACCTTCCCCGGCCAGCCGC
TCGACGACAAGTACGCCGGCAACGTGGTGGACATCTGCCCGGTCGGCGCGCTCACCTCGACCGACTTCCGGTTCCGCGGC
CGCGTCTGGTTCATGAGCTCGGCCCGCTCGGTCTGCACCGGCTGCGCGCGCGGCTGCAACACCTTCCTCGACTACCTGAA
CGACGTCACCTACCGCTACCGCCCGCGGGAGAACGACGCCGTGAACCAGGAGTGGATGTGCGACGACGGCCGCACGTCCT
ACAAGTACCTGAACGCCGGCCGCGTGCTGGTGGCGCGCGAGGGCCGGGGCGCGAACGCGCAGCCGCTCGCCCGCAAGGTC
GCGCCGCGCCGCGCCGCCGAGGTGCTGCTGCCGCACGTCGCGGCGGGCTCGCTGGCGGTGCTGCTCTCGCCGGTCGCGTC
GCTCGAGGACCTCCTGGTGGCCTGCAAGGTCGCGAAGGAGGGGCTGAAGGTCGCCGAGGTCTACGCCGGCGGCCGCGCCG
ACGGCTGGCAGGACGACTTCCTGAAGCGCGCCGACGAGAACCCCAACCGCAAGGGGCTCGAGCTCGCCGCGGCCGCCTAC
GGCCTCGCGGTCCGGCCGTTCGCGGACCTGGTCGCCGCGGCCGGCGCCGGCAAGGTGAAGGCGCTCTGGGCGGTCGGCAC
CGAGGTGCCGGACGCGAAGGGCGCCGAGAAGCTCGGCGCGCTCGAGGTCGTGGCGCAGTCGTACGGCGACACGGCGCTCG
CGCAGCACGCCACGGTGCTCCTGCCGGCGTCGCCGCACTCGGAGATGGACGGCACGTTCGTCAACTTCGAGGGGCGCGCG
CAGCGCTTCGAGATGGCGTACTTCCCGAAGGGCGAGTCGCGGCCGCACTGGGCGCTCGCCGCCGAGGTCGGGGCGGCGCT
GGGGTTGCCGCTCGCGTTCGCGAGCGGCCGCGAGGTGTTCGCGGCGCTCGGGCCGCAGCTCGGGGGCGCGCTGGGCGACT
TCGCCTGGGACTCGCTGCCGTCCACCGGCAAGCGGCTCGGGATCGTCCCGCTCGCCGCCGGCACCGTCGATGGCCGCCTG
CCGGGCAACCGCGACCGCGTGCCGTCCGAGACCACCGAGGATTACCGCCGCGCGATGTCGCGCACGTCGTAG

Upstream 100 bases:

>100_bases
AGGGTTCGCTGCTGTCCGACCTCATCCCCACCTTCGACAGCATCAACATGATCGGCGGCGAGGTGGAGCAGTAGCCTCGC
CCGGGAACCAGGAGCCTCCG

Downstream 100 bases:

>100_bases
GAGGGAGAGCCGGTGAACCGATTCTTCGGAATGCTCCTCGTCATCGCGGCGACGCTGGCCGGCCTGGTCGTCCTGTCGGC
CGGGTTCTACCTGGCCGCCG

Product: ferredoxin

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MAEEKKPDAAPPKPPGPPAPPPPKNPGFVTAIVDGKEVVVKPGTTVIEAAKAVGIDIPYYCYHKRLSIAANCRMCLVEMS
NAPGGKLMPACQMPVAEGVTVKTDTPRVKDQQRATLEFLLLNHPVDCSICDQAGECKLQDYYMAYDRQPSRLDVPKVVKG
KRVELGPTVTLDQERCILCTRCVRFMREVAENPQLGVAQRGNESFITTFPGQPLDDKYAGNVVDICPVGALTSTDFRFRG
RVWFMSSARSVCTGCARGCNTFLDYLNDVTYRYRPRENDAVNQEWMCDDGRTSYKYLNAGRVLVAREGRGANAQPLARKV
APRRAAEVLLPHVAAGSLAVLLSPVASLEDLLVACKVAKEGLKVAEVYAGGRADGWQDDFLKRADENPNRKGLELAAAAY
GLAVRPFADLVAAAGAGKVKALWAVGTEVPDAKGAEKLGALEVVAQSYGDTALAQHATVLLPASPHSEMDGTFVNFEGRA
QRFEMAYFPKGESRPHWALAAEVGAALGLPLAFASGREVFAALGPQLGGALGDFAWDSLPSTGKRLGIVPLAAGTVDGRL
PGNRDRVPSETTEDYRRAMSRTS

Sequences:

>Translated_583_residues
MAEEKKPDAAPPKPPGPPAPPPPKNPGFVTAIVDGKEVVVKPGTTVIEAAKAVGIDIPYYCYHKRLSIAANCRMCLVEMS
NAPGGKLMPACQMPVAEGVTVKTDTPRVKDQQRATLEFLLLNHPVDCSICDQAGECKLQDYYMAYDRQPSRLDVPKVVKG
KRVELGPTVTLDQERCILCTRCVRFMREVAENPQLGVAQRGNESFITTFPGQPLDDKYAGNVVDICPVGALTSTDFRFRG
RVWFMSSARSVCTGCARGCNTFLDYLNDVTYRYRPRENDAVNQEWMCDDGRTSYKYLNAGRVLVAREGRGANAQPLARKV
APRRAAEVLLPHVAAGSLAVLLSPVASLEDLLVACKVAKEGLKVAEVYAGGRADGWQDDFLKRADENPNRKGLELAAAAY
GLAVRPFADLVAAAGAGKVKALWAVGTEVPDAKGAEKLGALEVVAQSYGDTALAQHATVLLPASPHSEMDGTFVNFEGRA
QRFEMAYFPKGESRPHWALAAEVGAALGLPLAFASGREVFAALGPQLGGALGDFAWDSLPSTGKRLGIVPLAAGTVDGRL
PGNRDRVPSETTEDYRRAMSRTS
>Mature_582_residues
AEEKKPDAAPPKPPGPPAPPPPKNPGFVTAIVDGKEVVVKPGTTVIEAAKAVGIDIPYYCYHKRLSIAANCRMCLVEMSN
APGGKLMPACQMPVAEGVTVKTDTPRVKDQQRATLEFLLLNHPVDCSICDQAGECKLQDYYMAYDRQPSRLDVPKVVKGK
RVELGPTVTLDQERCILCTRCVRFMREVAENPQLGVAQRGNESFITTFPGQPLDDKYAGNVVDICPVGALTSTDFRFRGR
VWFMSSARSVCTGCARGCNTFLDYLNDVTYRYRPRENDAVNQEWMCDDGRTSYKYLNAGRVLVAREGRGANAQPLARKVA
PRRAAEVLLPHVAAGSLAVLLSPVASLEDLLVACKVAKEGLKVAEVYAGGRADGWQDDFLKRADENPNRKGLELAAAAYG
LAVRPFADLVAAAGAGKVKALWAVGTEVPDAKGAEKLGALEVVAQSYGDTALAQHATVLLPASPHSEMDGTFVNFEGRAQ
RFEMAYFPKGESRPHWALAAEVGAALGLPLAFASGREVFAALGPQLGGALGDFAWDSLPSTGKRLGIVPLAAGTVDGRLP
GNRDRVPSETTEDYRRAMSRTS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=280, Percent_Identity=41.4285714285714, Blast_Score=234, Evalue=2e-61,
Organism=Escherichia coli, GI145693161, Length=273, Percent_Identity=33.6996336996337, Blast_Score=176, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI32566231, Length=300, Percent_Identity=43, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17565758, Length=300, Percent_Identity=43, Blast_Score=241, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI193209088, Length=271, Percent_Identity=43.5424354243542, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24640559, Length=288, Percent_Identity=41.6666666666667, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24640557, Length=288, Percent_Identity=41.6666666666667, Blast_Score=234, Evalue=1e-61,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 62720; Mature: 62589

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEKKPDAAPPKPPGPPAPPPPKNPGFVTAIVDGKEVVVKPGTTVIEAAKAVGIDIPYY
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHCCCCCHH
CYHKRLSIAANCRMCLVEMSNAPGGKLMPACQMPVAEGVTVKTDTPRVKDQQRATLEFLL
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHCCCCCCCEEEECCCCCCCCHHHHEEEEEE
LNHPVDCSICDQAGECKLQDYYMAYDRQPSRLDVPKVVKGKRVELGPTVTLDQERCILCT
ECCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCHHHCCCEEECCCEEEECCCHHHHHH
RCVRFMREVAENPQLGVAQRGNESFITTFPGQPLDDKYAGNVVDICPVGALTSTDFRFRG
HHHHHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEE
RVWFMSSARSVCTGCARGCNTFLDYLNDVTYRYRPRENDAVNQEWMCDDGRTSYKYLNAG
EEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEECCCCCCCEEEECCC
RVLVAREGRGANAQPLARKVAPRRAAEVLLPHVAAGSLAVLLSPVASLEDLLVACKVAKE
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHC
GLKVAEVYAGGRADGWQDDFLKRADENPNRKGLELAAAAYGLAVRPFADLVAAAGAGKVK
CCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEE
ALWAVGTEVPDAKGAEKLGALEVVAQSYGDTALAQHATVLLPASPHSEMDGTFVNFEGRA
EEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCCCCCCEEEEECCCC
QRFEMAYFPKGESRPHWALAAEVGAALGLPLAFASGREVFAALGPQLGGALGDFAWDSLP
CEEEEEECCCCCCCCCEEHHHHHHHHHCCCEEECCCHHHHHHHCHHHCCHHHHHHHHCCC
STGKRLGIVPLAAGTVDGRLPGNRDRVPSETTEDYRRAMSRTS
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AEEKKPDAAPPKPPGPPAPPPPKNPGFVTAIVDGKEVVVKPGTTVIEAAKAVGIDIPYY
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHCCCCCHH
CYHKRLSIAANCRMCLVEMSNAPGGKLMPACQMPVAEGVTVKTDTPRVKDQQRATLEFLL
HHHHHHHHHCCCEEEEEEECCCCCCCCCCHHCCCCCCCEEEECCCCCCCCHHHHEEEEEE
LNHPVDCSICDQAGECKLQDYYMAYDRQPSRLDVPKVVKGKRVELGPTVTLDQERCILCT
ECCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCHHHCCCEEECCCEEEECCCHHHHHH
RCVRFMREVAENPQLGVAQRGNESFITTFPGQPLDDKYAGNVVDICPVGALTSTDFRFRG
HHHHHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEE
RVWFMSSARSVCTGCARGCNTFLDYLNDVTYRYRPRENDAVNQEWMCDDGRTSYKYLNAG
EEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEECCCCCCCEEEECCC
RVLVAREGRGANAQPLARKVAPRRAAEVLLPHVAAGSLAVLLSPVASLEDLLVACKVAKE
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHC
GLKVAEVYAGGRADGWQDDFLKRADENPNRKGLELAAAAYGLAVRPFADLVAAAGAGKVK
CCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEE
ALWAVGTEVPDAKGAEKLGALEVVAQSYGDTALAQHATVLLPASPHSEMDGTFVNFEGRA
EEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCCCCCCEEEEECCCC
QRFEMAYFPKGESRPHWALAAEVGAALGLPLAFASGREVFAALGPQLGGALGDFAWDSLP
CEEEEEECCCCCCCCCEEHHHHHHHHHCCCEEECCCHHHHHHHCHHHCCHHHHHHHHCCC
STGKRLGIVPLAAGTVDGRLPGNRDRVPSETTEDYRRAMSRTS
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]