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The map label for this gene is nuoC2 [H]

Identifier: 220916487

GI number: 220916487

Start: 1545158

End: 1545685

Strand: Direct

Name: nuoC2 [H]

Synonym: A2cp1_1381

Alternate gene names: 220916487

Gene position: 1545158-1545685 (Clockwise)

Preceding gene: 220916486

Following gene: 220916488

Centisome position: 30.72

GC content: 70.64

Gene sequence:

>528_bases
ATGTCCAAGGCCGTGATCGCCGCGCTCGTCGAGCGCTTCCCGGATGCCGTCCACGCCCCGTACGAGGGCGTCGGCGGCGA
CGACTGCGCGTTCGTGGAGCGGAGCCGGATCGTCGACGTGTGCCGCTTCCTGAAGGAAGACCCGTCGCTCGCCTTCAACA
TGTCGCCGTACATCACGGCGGTGGACTACCTCGGCGCCAGCCCGCGCTTCGAGGTCGTCTACAACCTGCTCTCGACCGTG
CACAACACGCGCGTGCGCCTGCGGGTGAAGGTGCCCGAGGGGCCCGAGGGCGTCGTGCCGTCGGTCACCGGCCTGTGGCG
CGGCGCCGACTGGTTCGAGCGCTACTGCTGGGACATGTACGGGATCCCGTTCTCCGGGCACCCCGACATGCGCCGCCTGC
TCATGTACGACGAGTTCGAGGGGCACCCGCTGCGCAAGGACTACCCGCTGCGCGGCCGGCAGCCGCTGGTCGTCGAGCGC
GAGGTGCACGACATCTTCCGCGGGCCCGGGCCCGCGTCGCGCGACTAG

Upstream 100 bases:

>100_bases
TGCTCCAGAAGAAGATCCAGAACCAGTCGCACAAGCTCATCGACCGCACGCCGCTCCCGGTGATCTCGGGCGGCGCCGGC
CGGTAGGCGCGAGGACCCTC

Downstream 100 bases:

>100_bases
CCGTTTCTTTCCACGCCGCCGGGCCGCGCCGAGCGCGCTGCGGCGGGCGCCCCTCCGGAAGGACCGGGCGCGCGGAGGAC
GAGATGAGCGAGGCGAAGGG

Product: NADH (or F420H2) dehydrogenase, subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C 2; NDH-1 subunit C 2 [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSKAVIAALVERFPDAVHAPYEGVGGDDCAFVERSRIVDVCRFLKEDPSLAFNMSPYITAVDYLGASPRFEVVYNLLSTV
HNTRVRLRVKVPEGPEGVVPSVTGLWRGADWFERYCWDMYGIPFSGHPDMRRLLMYDEFEGHPLRKDYPLRGRQPLVVER
EVHDIFRGPGPASRD

Sequences:

>Translated_175_residues
MSKAVIAALVERFPDAVHAPYEGVGGDDCAFVERSRIVDVCRFLKEDPSLAFNMSPYITAVDYLGASPRFEVVYNLLSTV
HNTRVRLRVKVPEGPEGVVPSVTGLWRGADWFERYCWDMYGIPFSGHPDMRRLLMYDEFEGHPLRKDYPLRGRQPLVVER
EVHDIFRGPGPASRD
>Mature_174_residues
SKAVIAALVERFPDAVHAPYEGVGGDDCAFVERSRIVDVCRFLKEDPSLAFNMSPYITAVDYLGASPRFEVVYNLLSTVH
NTRVRLRVKVPEGPEGVVPSVTGLWRGADWFERYCWDMYGIPFSGHPDMRRLLMYDEFEGHPLRKDYPLRGRQPLVVERE
VHDIFRGPGPASRD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=133, Percent_Identity=39.0977443609023, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI145693162, Length=178, Percent_Identity=35.3932584269663, Blast_Score=96, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=166, Percent_Identity=37.3493975903614, Blast_Score=106, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32563621, Length=166, Percent_Identity=36.7469879518072, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24656494, Length=144, Percent_Identity=37.5, Blast_Score=97, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19943; Mature: 19812

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAVIAALVERFPDAVHAPYEGVGGDDCAFVERSRIVDVCRFLKEDPSLAFNMSPYITA
CCHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHH
VDYLGASPRFEVVYNLLSTVHNTRVRLRVKVPEGPEGVVPSVTGLWRGADWFERYCWDMY
HHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHC
GIPFSGHPDMRRLLMYDEFEGHPLRKDYPLRGRQPLVVEREVHDIFRGPGPASRD
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKAVIAALVERFPDAVHAPYEGVGGDDCAFVERSRIVDVCRFLKEDPSLAFNMSPYITA
CHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHH
VDYLGASPRFEVVYNLLSTVHNTRVRLRVKVPEGPEGVVPSVTGLWRGADWFERYCWDMY
HHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHC
GIPFSGHPDMRRLLMYDEFEGHPLRKDYPLRGRQPLVVEREVHDIFRGPGPASRD
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA