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The map label for this gene is nuoB1 [H]

Identifier: 220916486

GI number: 220916486

Start: 1544595

End: 1545143

Strand: Direct

Name: nuoB1 [H]

Synonym: A2cp1_1380

Alternate gene names: 220916486

Gene position: 1544595-1545143 (Clockwise)

Preceding gene: 220916485

Following gene: 220916487

Centisome position: 30.71

GC content: 68.49

Gene sequence:

>549_bases
ATGGCATCGGAGCTCGACGGGCTGCCCGTCATCGCCACGCGCCGGGAGGAGGCGGAGGGGTTCCTCCAGGGCCTCGTCTC
GAAGAGCCTGGGCTGGGCGCGCAAGTACTCCCTGTTCACCTATCCGTTCGTCACGGCCTGCTGCGGCATGGAGTACATGA
CCATGGCCTCGGCGCGGTACGACTCGGACCGGTTCGGCGCCGCCATGCCGCGGTTCTCGCCGCGCCAGGCCGACCTGCTG
ATGGTGGTGGGCACGGTGAACTGCAAGCAGGCGCCCATCCTCCAGCGCGTCTACGAGCAGATGGCCGATCCGAAGTGGGT
GATGGCGTTCGGCGTCTGCGCCAGCTCCGGCGGGTTCTACGACAACTACGCGACGGTGCAGGGCATCGACCGGGTGATCC
CGGTGGACGTCTACGTGCCCGGCTGTCCGCCGCGCCCGGAGCAGGTGCTCGACGGCATCATGCTGCTCCAGAAGAAGATC
CAGAACCAGTCGCACAAGCTCATCGACCGCACGCCGCTCCCGGTGATCTCGGGCGGCGCCGGCCGGTAG

Upstream 100 bases:

>100_bases
TCTCCATGGGGATCTTCGTGTTCACCCTGGTCGCGGGCCTCGTCTACGTCTGGAAGAAGGGCGTCCTCGACTGGGCGGAT
TAGAGAGGAGCGACCGCACA

Downstream 100 bases:

>100_bases
GCGCGAGGACCCTCATGTCCAAGGCCGTGATCGCCGCGCTCGTCGAGCGCTTCCCGGATGCCGTCCACGCCCCGTACGAG
GGCGTCGGCGGCGACGACTG

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B 1; NDH-1 subunit B 1 [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MASELDGLPVIATRREEAEGFLQGLVSKSLGWARKYSLFTYPFVTACCGMEYMTMASARYDSDRFGAAMPRFSPRQADLL
MVVGTVNCKQAPILQRVYEQMADPKWVMAFGVCASSGGFYDNYATVQGIDRVIPVDVYVPGCPPRPEQVLDGIMLLQKKI
QNQSHKLIDRTPLPVISGGAGR

Sequences:

>Translated_182_residues
MASELDGLPVIATRREEAEGFLQGLVSKSLGWARKYSLFTYPFVTACCGMEYMTMASARYDSDRFGAAMPRFSPRQADLL
MVVGTVNCKQAPILQRVYEQMADPKWVMAFGVCASSGGFYDNYATVQGIDRVIPVDVYVPGCPPRPEQVLDGIMLLQKKI
QNQSHKLIDRTPLPVISGGAGR
>Mature_181_residues
ASELDGLPVIATRREEAEGFLQGLVSKSLGWARKYSLFTYPFVTACCGMEYMTMASARYDSDRFGAAMPRFSPRQADLLM
VVGTVNCKQAPILQRVYEQMADPKWVMAFGVCASSGGFYDNYATVQGIDRVIPVDVYVPGCPPRPEQVLDGIMLLQKKIQ
NQSHKLIDRTPLPVISGGAGR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=156, Percent_Identity=46.7948717948718, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1788624, Length=167, Percent_Identity=46.7065868263473, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1789074, Length=185, Percent_Identity=33.5135135135135, Blast_Score=93, Evalue=8e-21,
Organism=Escherichia coli, GI1788834, Length=129, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17509685, Length=135, Percent_Identity=51.1111111111111, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18859983, Length=133, Percent_Identity=50.3759398496241, Blast_Score=149, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24642371, Length=133, Percent_Identity=50.3759398496241, Blast_Score=149, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24651058, Length=133, Percent_Identity=50.3759398496241, Blast_Score=147, Evalue=5e-36,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 20064; Mature: 19932

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASELDGLPVIATRREEAEGFLQGLVSKSLGWARKYSLFTYPFVTACCGMEYMTMASARY
CCCCCCCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
DSDRFGAAMPRFSPRQADLLMVVGTVNCKQAPILQRVYEQMADPKWVMAFGVCASSGGFY
CCHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCC
DNYATVQGIDRVIPVDVYVPGCPPRPEQVLDGIMLLQKKIQNQSHKLIDRTPLPVISGGA
CCCHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCC
GR
CC
>Mature Secondary Structure 
ASELDGLPVIATRREEAEGFLQGLVSKSLGWARKYSLFTYPFVTACCGMEYMTMASARY
CCCCCCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
DSDRFGAAMPRFSPRQADLLMVVGTVNCKQAPILQRVYEQMADPKWVMAFGVCASSGGFY
CCHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCC
DNYATVQGIDRVIPVDVYVPGCPPRPEQVLDGIMLLQKKIQNQSHKLIDRTPLPVISGGA
CCCHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA