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The map label for this gene is virB8 [H]

Identifier: 220916249

GI number: 220916249

Start: 1274360

End: 1275037

Strand: Direct

Name: virB8 [H]

Synonym: A2cp1_1142

Alternate gene names: 220916249

Gene position: 1274360-1275037 (Clockwise)

Preceding gene: 220916248

Following gene: 220916250

Centisome position: 25.34

GC content: 69.62

Gene sequence:

>678_bases
ATGAGGGCGGGGGACCTGGAGCAGTACCTCGAGGAGAGCAGGGGGCTTGAGCGCGACTACCTCGAGGAGCTCGTGCGCTC
GAGGAGGGTGGCGTGGCGGGTGGCGGCGAGCGCGGCCGTGCTAGTAGCGGCCGCGCTCGCCACGGTGGTGGCGCTGGTCC
CGCTGAAGCGCGTCGAGGCGTTCGTGCTGCGGGTCGACAACGCCACGGGAGCGGTGGATCTGGTGACGACGCTCCGCGAC
GGGCAGGCGGGCTACGGCGAGGTGGTCGACCGGTATTTCCTCAACAAGTACGTCCTCGCCCGGGAGAGCTACGATTACGA
GACGCTCCAGACCGCGTACGACACGACCGCGCTCATGAGCAGCGGCGAGGTCCAGCGCGAGTACGCGGGGCTTTTCGACG
GGCCGAAGGCGCGGGACAAGGTCCTCGCGAACCGCGTCCGGATCGTCGTGAAGGTCCGTTCAATCGCGCCTGGCACGACC
CGCAACACCGCGGTCGTGCGATTCGCGACGCGCGCGGCGCACGCCGATGGGACGAGCGAGGCGGAGGAGAGCCTCGTCGC
CACCATCGGATTCAGGTACGTGGGCGGCGCCATGCACGAGCAGGACCGGCTCGTGAACCCGCTCGGTTTCCAGGTGACGA
GCTATCGGGTCGATCCCGAGATCGCGGGCGGCGGGTGA

Upstream 100 bases:

>100_bases
TGAACCGGAGGGTGCCGCCCGAGGTGGAAGAGGCCGTGAGGGCGAACCATGCCAGCGGAGCGCAGCGGCAACCGCGACCC
GAGGGCGAGGTGGAGTGGCG

Downstream 100 bases:

>100_bases
GGGGAGGCGTTCATGCGCCGCGTGATCGTTCTCCTTCTCGCCATCGCCGTGTCCGCCGGAGCCTCCGAAGGCGGGCCGGA
CCGCCGGATTCGGTACGTGA

Product: VirB8 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRAGDLEQYLEESRGLERDYLEELVRSRRVAWRVAASAAVLVAAALATVVALVPLKRVEAFVLRVDNATGAVDLVTTLRD
GQAGYGEVVDRYFLNKYVLARESYDYETLQTAYDTTALMSSGEVQREYAGLFDGPKARDKVLANRVRIVVKVRSIAPGTT
RNTAVVRFATRAAHADGTSEAEESLVATIGFRYVGGAMHEQDRLVNPLGFQVTSYRVDPEIAGGG

Sequences:

>Translated_225_residues
MRAGDLEQYLEESRGLERDYLEELVRSRRVAWRVAASAAVLVAAALATVVALVPLKRVEAFVLRVDNATGAVDLVTTLRD
GQAGYGEVVDRYFLNKYVLARESYDYETLQTAYDTTALMSSGEVQREYAGLFDGPKARDKVLANRVRIVVKVRSIAPGTT
RNTAVVRFATRAAHADGTSEAEESLVATIGFRYVGGAMHEQDRLVNPLGFQVTSYRVDPEIAGGG
>Mature_225_residues
MRAGDLEQYLEESRGLERDYLEELVRSRRVAWRVAASAAVLVAAALATVVALVPLKRVEAFVLRVDNATGAVDLVTTLRD
GQAGYGEVVDRYFLNKYVLARESYDYETLQTAYDTTALMSSGEVQREYAGLFDGPKARDKVLANRVRIVVKVRSIAPGTT
RNTAVVRFATRAAHADGTSEAEESLVATIGFRYVGGAMHEQDRLVNPLGFQVTSYRVDPEIAGGG

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice [H]

COG id: COG3736

COG function: function code U; Type IV secretory pathway, component VirB8

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the virB8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007430 [H]

Pfam domain/function: PF04335 VirB8 [H]

EC number: NA

Molecular weight: Translated: 24621; Mature: 24621

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGDLEQYLEESRGLERDYLEELVRSRRVAWRVAASAAVLVAAALATVVALVPLKRVEA
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FVLRVDNATGAVDLVTTLRDGQAGYGEVVDRYFLNKYVLARESYDYETLQTAYDTTALMS
EHEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
SGEVQREYAGLFDGPKARDKVLANRVRIVVKVRSIAPGTTRNTAVVRFATRAAHADGTSE
CCCHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEEHHHHCCCCCCH
AEESLVATIGFRYVGGAMHEQDRLVNPLGFQVTSYRVDPEIAGGG
HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MRAGDLEQYLEESRGLERDYLEELVRSRRVAWRVAASAAVLVAAALATVVALVPLKRVEA
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FVLRVDNATGAVDLVTTLRDGQAGYGEVVDRYFLNKYVLARESYDYETLQTAYDTTALMS
EHEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
SGEVQREYAGLFDGPKARDKVLANRVRIVVKVRSIAPGTTRNTAVVRFATRAAHADGTSE
CCCHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEEHHHHCCCCCCH
AEESLVATIGFRYVGGAMHEQDRLVNPLGFQVTSYRVDPEIAGGG
HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]