Click here to switch to the map view.

The map label for this gene is virB6 [H]

Identifier: 220916247

GI number: 220916247

Start: 1273300

End: 1274175

Strand: Direct

Name: virB6 [H]

Synonym: A2cp1_1140

Alternate gene names: 220916247

Gene position: 1273300-1274175 (Clockwise)

Preceding gene: 220916246

Following gene: 220916248

Centisome position: 25.32

GC content: 68.49

Gene sequence:

>876_bases
ATGTTTCGCCTGTTCACGCCGCTCTTCGCGGAGCTCGACCGCATCAGCACCGCCTTCGCGCAGGACGTCTCCTCGCGCGT
CATCGTGGCCATCACGCCCGTGCTCGCGGCGGGCCTCACGGTCTGGTTCATCGCCTGGGGGATCCTCGTCATGCGGGGCG
CCGTGGACCAGCCCGTGCGTGAGTTTCTCGGGAAGGTCATCCGCACGGCGCTCATCGTTTCGGTAGCGCTCGGAGCAGGC
CTCTACCAGCGGGACGTCGTCGAGGTGATCCGCACGGTCCCTGACGACCTCGCCGCGGCGGTCGCCGGCGGCGAGGCGAA
CGTCCGGTTCGGCGCGGGTCCACTCGACACCGGCAGCACCCAGGCCGCCCTCATCGACCGGGCCGCGGGTCAGGGCCTCC
TGAAGGCGGAGGACGCCTTCGAGAAGGGCGGCCTCATGACGCAGCAAGGGATCGCCTTCTACACGTTTGGCGTTCTCATG
CTGCTCGCGACCGTCGTCATGGTCGGGGTCGGCGGCGCGCTCATCCTCGTCGCGAAGGTGATGCTGGCGCTCCTCGCCGG
GCTGGGCCCGCTCTTCATCGCGGCGCTCCTCTTCGACGCGACCAGGCGCTTCTTCGATCGGTGGATCGCGATGATCGCTA
CCTACGCGCTCGTCGTGGTGCTCTTTGCGGCGGTCTTCACCTTCATGCTCGCGATCTTCGCGAACTACATGTCCGGCGTC
GCCCTCGACGGGAACATGAACGTCGCCTACGGCATCGGCGGCGCGCTCATCCTCACGGTCGTCTCGGTCGCGATCCTGAA
GGAGCTGCACCACCTCGCGGTCGGGCTGGGCGGCGGGTACGCCCACCGCATCCTCCTCCTGGAGCGGTCGCGATGA

Upstream 100 bases:

>100_bases
CAGCAGAAGACCGACCTCGCGCAACGGATCCTCTCCGCATCCAACCGCGGGATGCCGCCGTGCTGCTCGGTCGACCCGGG
CGCGGGCGCGCGGAGGTGAC

Downstream 100 bases:

>100_bases
GGCCGCTCCTGTTCATCGCGCTGGCCTGCGCCTGCGCCACGGCGCCCGGACCCAAGCGGCCAGACGAGTCCCACCGGGTC
CCCGTGAACCGGAGGGTGCC

Product: TrbL/VirB6 plasmid conjugal transfer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MFRLFTPLFAELDRISTAFAQDVSSRVIVAITPVLAAGLTVWFIAWGILVMRGAVDQPVREFLGKVIRTALIVSVALGAG
LYQRDVVEVIRTVPDDLAAAVAGGEANVRFGAGPLDTGSTQAALIDRAAGQGLLKAEDAFEKGGLMTQQGIAFYTFGVLM
LLATVVMVGVGGALILVAKVMLALLAGLGPLFIAALLFDATRRFFDRWIAMIATYALVVVLFAAVFTFMLAIFANYMSGV
ALDGNMNVAYGIGGALILTVVSVAILKELHHLAVGLGGGYAHRILLLERSR

Sequences:

>Translated_291_residues
MFRLFTPLFAELDRISTAFAQDVSSRVIVAITPVLAAGLTVWFIAWGILVMRGAVDQPVREFLGKVIRTALIVSVALGAG
LYQRDVVEVIRTVPDDLAAAVAGGEANVRFGAGPLDTGSTQAALIDRAAGQGLLKAEDAFEKGGLMTQQGIAFYTFGVLM
LLATVVMVGVGGALILVAKVMLALLAGLGPLFIAALLFDATRRFFDRWIAMIATYALVVVLFAAVFTFMLAIFANYMSGV
ALDGNMNVAYGIGGALILTVVSVAILKELHHLAVGLGGGYAHRILLLERSR
>Mature_291_residues
MFRLFTPLFAELDRISTAFAQDVSSRVIVAITPVLAAGLTVWFIAWGILVMRGAVDQPVREFLGKVIRTALIVSVALGAG
LYQRDVVEVIRTVPDDLAAAVAGGEANVRFGAGPLDTGSTQAALIDRAAGQGLLKAEDAFEKGGLMTQQGIAFYTFGVLM
LLATVVMVGVGGALILVAKVMLALLAGLGPLFIAALLFDATRRFFDRWIAMIATYALVVVLFAAVFTFMLAIFANYMSGV
ALDGNMNVAYGIGGALILTVVSVAILKELHHLAVGLGGGYAHRILLLERSR

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice [H]

COG id: COG3704

COG function: function code U; Type IV secretory pathway, VirB6 components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbL/virB6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007688 [H]

Pfam domain/function: PF04610 TrbL [H]

EC number: NA

Molecular weight: Translated: 30759; Mature: 30759

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00027 HOMEOBOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRLFTPLFAELDRISTAFAQDVSSRVIVAITPVLAAGLTVWFIAWGILVMRGAVDQPVR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EFLGKVIRTALIVSVALGAGLYQRDVVEVIRTVPDDLAAAVAGGEANVRFGAGPLDTGST
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCCCCCCCH
QAALIDRAAGQGLLKAEDAFEKGGLMTQQGIAFYTFGVLMLLATVVMVGVGGALILVAKV
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MLALLAGLGPLFIAALLFDATRRFFDRWIAMIATYALVVVLFAAVFTFMLAIFANYMSGV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
ALDGNMNVAYGIGGALILTVVSVAILKELHHLAVGLGGGYAHRILLLERSR
EECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEECCC
>Mature Secondary Structure
MFRLFTPLFAELDRISTAFAQDVSSRVIVAITPVLAAGLTVWFIAWGILVMRGAVDQPVR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EFLGKVIRTALIVSVALGAGLYQRDVVEVIRTVPDDLAAAVAGGEANVRFGAGPLDTGST
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECCCCCCCCCH
QAALIDRAAGQGLLKAEDAFEKGGLMTQQGIAFYTFGVLMLLATVVMVGVGGALILVAKV
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MLALLAGLGPLFIAALLFDATRRFFDRWIAMIATYALVVVLFAAVFTFMLAIFANYMSGV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
ALDGNMNVAYGIGGALILTVVSVAILKELHHLAVGLGGGYAHRILLLERSR
EECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]