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The map label for this gene is virB5 [H]

Identifier: 220916246

GI number: 220916246

Start: 1272603

End: 1273298

Strand: Direct

Name: virB5 [H]

Synonym: A2cp1_1139

Alternate gene names: 220916246

Gene position: 1272603-1273298 (Clockwise)

Preceding gene: 220916245

Following gene: 220916247

Centisome position: 25.3

GC content: 68.82

Gene sequence:

>696_bases
ATGAAACACCTCCGAACGTTGGTAGTCGCCGGAGGCTTCGCGTTCGCGACCGCGGCGCACGCGCAGGGCATCCCGGTGTT
CGACTCGTCGAGCTTCGGTCAGATGGTTCTGTCGGTGAAGGCGCTTGGGGATCAGCTCAGACAGCTCCAGGCCACGTACC
AGGCCGTGAGCGGAACCCGTAACCTCGGTGAAGTGCTCTACAACCCGGCGCTCCGAGGTTACCTGCCGGCGGACTGGGCG
CGCGTTTACGACACCGCGGCCGCAGGAGGCTACCCCGGGATCTCCGGGCCACTCCGGGCCGTCCAGGACGGTGAGCGGCT
TCGCGGCACCGTCACCGACGCGCAGGCGAGCATCGCGGCTCGGAGCCGGACGACAGCGATGGCCGACAAGGCTACGGGCC
TGCATGCGTTCGAGGGTGCGCGGGCGCGCCTCTCCCAGATCGAGCAGCTCATGCGGCAGATCAACCTCACGCACGATGCC
AAGGGCGTACAGGAGATCCAGGCGCGCATCGCGGTGGAGCAGGCCGCGGTGCAGAACGAGACGACGAAGCTCCAGCTCGT
CGCCATGCTCCAGCGCGCTGAGGAGCGGCTCGTCGAGCAGCAGAAGACCGACCTCGCGCAACGGATCCTCTCCGCATCCA
ACCGCGGGATGCCGCCGTGCTGCTCGGTCGACCCGGGCGCGGGCGCGCGGAGGTGA

Upstream 100 bases:

>100_bases
CGTTCGAGCGAGCCGTCGCGCGCCGGCTGGGGATCGACATCGGTCCGCTGCGGCAGGAGCTGCAGAGGGCGGCCCGCACC
GAGCGGCCAGGGAGCCATCC

Downstream 100 bases:

>100_bases
CATGTTTCGCCTGTTCACGCCGCTCTTCGCGGAGCTCGACCGCATCAGCACCGCCTTCGCGCAGGACGTCTCCTCGCGCG
TCATCGTGGCCATCACGCCC

Product: P-type DNA transfer protein VirB5

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKHLRTLVVAGGFAFATAAHAQGIPVFDSSSFGQMVLSVKALGDQLRQLQATYQAVSGTRNLGEVLYNPALRGYLPADWA
RVYDTAAAGGYPGISGPLRAVQDGERLRGTVTDAQASIAARSRTTAMADKATGLHAFEGARARLSQIEQLMRQINLTHDA
KGVQEIQARIAVEQAAVQNETTKLQLVAMLQRAEERLVEQQKTDLAQRILSASNRGMPPCCSVDPGAGARR

Sequences:

>Translated_231_residues
MKHLRTLVVAGGFAFATAAHAQGIPVFDSSSFGQMVLSVKALGDQLRQLQATYQAVSGTRNLGEVLYNPALRGYLPADWA
RVYDTAAAGGYPGISGPLRAVQDGERLRGTVTDAQASIAARSRTTAMADKATGLHAFEGARARLSQIEQLMRQINLTHDA
KGVQEIQARIAVEQAAVQNETTKLQLVAMLQRAEERLVEQQKTDLAQRILSASNRGMPPCCSVDPGAGARR
>Mature_231_residues
MKHLRTLVVAGGFAFATAAHAQGIPVFDSSSFGQMVLSVKALGDQLRQLQATYQAVSGTRNLGEVLYNPALRGYLPADWA
RVYDTAAAGGYPGISGPLRAVQDGERLRGTVTDAQASIAARSRTTAMADKATGLHAFEGARARLSQIEQLMRQINLTHDA
KGVQEIQARIAVEQAAVQNETTKLQLVAMLQRAEERLVEQQKTDLAQRILSASNRGMPPCCSVDPGAGARR

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the virb5 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012991
- InterPro:   IPR014158
- InterPro:   IPR023220 [H]

Pfam domain/function: PF07996 T4SS [H]

EC number: NA

Molecular weight: Translated: 24756; Mature: 24756

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLRTLVVAGGFAFATAAHAQGIPVFDSSSFGQMVLSVKALGDQLRQLQATYQAVSGTR
CCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
NLGEVLYNPALRGYLPADWARVYDTAAAGGYPGISGPLRAVQDGERLRGTVTDAQASIAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHCHHHHHHHHHHH
RSRTTAMADKATGLHAFEGARARLSQIEQLMRQINLTHDAKGVQEIQARIAVEQAAVQNE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
TTKLQLVAMLQRAEERLVEQQKTDLAQRILSASNRGMPPCCSVDPGAGARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKHLRTLVVAGGFAFATAAHAQGIPVFDSSSFGQMVLSVKALGDQLRQLQATYQAVSGTR
CCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
NLGEVLYNPALRGYLPADWARVYDTAAAGGYPGISGPLRAVQDGERLRGTVTDAQASIAA
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHCHHHHHHHHHHH
RSRTTAMADKATGLHAFEGARARLSQIEQLMRQINLTHDAKGVQEIQARIAVEQAAVQNE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
TTKLQLVAMLQRAEERLVEQQKTDLAQRILSASNRGMPPCCSVDPGAGARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]