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The map label for this gene is kup

Identifier: 220916120

GI number: 220916120

Start: 1132772

End: 1134787

Strand: Direct

Name: kup

Synonym: A2cp1_1007

Alternate gene names: 220916120

Gene position: 1132772-1134787 (Clockwise)

Preceding gene: 220916111

Following gene: 220916121

Centisome position: 22.52

GC content: 71.63

Gene sequence:

>2016_bases
ATGTCCCAGATCCCCTCACCCAACGACCCCGCGTCAACCGGCGCCGCGCCCTCCTCCGCCGCCGTTCCGGCCGGCCCCAG
CGCCACGCCCGCCCCGTCGCCCACCGCCGGCTTCTCGCTGCCCGGGCACCGCCCGCCCCCCAGCGGGAAGGCGCTCGCGG
CGCTCGCGGTCGGCGCGCTCGGGGTCGTCTACGGGGACATCGGGACGAGCCCGCTCTACTCGCTGAAGGAGTGCTTCGGG
GGGCCGCACGGGGTCCGGCCCACCGACGCGAACGTGCTCGGCGTCCTGTCGCTCGTGTTCTGGGCGATGACGTTCGTGGT
GACGTTCAAGTACATGTCGTTCGTCATGCGCGCGGACAACCGCGGGGAGGGCGGGATCCTCGCGCTCATGGCGCTGGTGG
GGAAGACCGAGACCACGCGCCTCGGCCGGCGCATGCTGCTCATGCTGGGCCTGTTCGGCGCCGCGCTGCTGTACGGCGAC
GGCATCATCACGCCCGCCATCTCGGTGCTGGGCGCGGTGGAGGGCGTCGCCGTCGCGGCGCCGGCCATGGAGCGGGCGGT
GGTGCCGGCCACCGTGGTGATCCTGGTGTTCCTGTTCCTGTTCCAGAAGCAGGGCACCGCCAAGGTCGGCGCGGTGTTCG
GCCCGGTCATGCTGGTCTGGTTCGCGACCATCGCGGTGCTGGGCGTGCGCGGCATCCTCCACGACCCCACCATCCTGCGC
GCGCTCCTGCCCACCCACGGGCTCTCCTTCTTCGCGCGGAACGGCTGGCACGGCTTCCTGGTGCTGGGCGGCGTGGTGCT
GGTCATCACCGGCGGCGAGGCGCTGTACGCGGACATGGGCCACTTCGGGAAGCGCCCCATCCGCGTGGCGTGGCTGGGCC
TCGCCATGCCGGCGCTGCTCCTCAACTACCTGGGGCAGGGGGCGCTGCTGCTCCACGACCCCGGCGCCGCCCGCAACCCG
TTCTACCTGCTCGCGCCGGAGTGGGCGCTCTACCCCACCATCGCCATCGCCACCGCCGCGGCCATCGTGGCGTCGCAGGC
CCTCATCTCCGGCGCGTACTCGCTCACCCAGCAGGCCATCCAGCTCGGCTACTCGCCGCGCGTCACCATCCGCCACACCT
CGCAGCGCGAGATCGGGCAGATCTACCTGCCCGAGGTGAACTGGATGCTCGGCACCGCCTGCCTGGCGCTGGTGCTCGGG
TTCCAGACCTCCTCGCGCCTCGCCTCTGCGTACGGCATCGCCGTCACCGGGACGATGATCGTCACCACGCTCCTGTTCCA
CCGGGTGATGCGCGACCGGTGGGGCTGGGCGCGCTGGAAGGCCTGGCCGCTCACGGTCCTGTTCCTCACCGTGGACGCGG
CGTTCTTCCTCGCGAACGTGGTCAAGTTCCGCGACGGCGGCTGGTTCCCCATCGCGGCGGCGGCGCTGGTGTTCACGCTC
ATGTCCACCTGGAAGCGCGGCCGCGACGCGCTCGCGCTCATGCTGAAGGACGCCGGGCTCCCGCTCGACCTGTTCATGGC
CGACGTGGCGCGGCGCAAGGTCCAGCGCGTGGCCGGGACGGCGGTGTTCATGACCTCCAACCCCGGCGGCGTCCCGCCGG
TGCTGCTCCACCACCTGAAGCACAACAAGGTGCTGCACGAGCGCGTGGTCCTGGTCTCCATCCTGGCGCACGAGATCCCG
TTCGTGAACGAGCCGGAGCGGGTGAACGCGCGCGAGCTGGGCAGCGGCTTCTTCCAGGTGATCGCGCACTACGGCTTCAT
GGAGACGCCGGACGTGCCGGCGCTGCTCGACTCGCTCCCCCGCCGCGAGCTGGCCGGGCCGCGCCTCACCATCGTCCCCA
TGGAGACGACGTACTTCCTCGGGCGCGAGACGCTGCTCGCGAACGGCCCGTCGACCATCCCGACCTGGCGCAAGCGGCTG
TTCATCGTGATGGCCCGCAACGCGCAGACCGCGAGCGCGTTCTTCGGCCTGCCACCCAACCGCGTGGTGGAGATGGGCGC
GCAGATCCAGCTGTAG

Upstream 100 bases:

>100_bases
TCGAATTCCAGCCTCCGTCTGCAGGGTTCGCCCTGCGAGCGGGTTTGGGGCTCGACGGCCGGGTTCCAATCTGCTTACTT
CGCGCCCTCCTTTCCTCCGG

Downstream 100 bases:

>100_bases
CGCTCGAGCCGCGATGCGCTGGCCGAACGCCCTCCGCTCGCTCCGCCAGCGCGACCTGCGGCTGTTCTTCGCCGGCCAGA
CCGTGTCGCTGGCCGGCAAC

Product: K potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSQIPSPNDPASTGAAPSSAAVPAGPSATPAPSPTAGFSLPGHRPPPSGKALAALAVGALGVVYGDIGTSPLYSLKECFG
GPHGVRPTDANVLGVLSLVFWAMTFVVTFKYMSFVMRADNRGEGGILALMALVGKTETTRLGRRMLLMLGLFGAALLYGD
GIITPAISVLGAVEGVAVAAPAMERAVVPATVVILVFLFLFQKQGTAKVGAVFGPVMLVWFATIAVLGVRGILHDPTILR
ALLPTHGLSFFARNGWHGFLVLGGVVLVITGGEALYADMGHFGKRPIRVAWLGLAMPALLLNYLGQGALLLHDPGAARNP
FYLLAPEWALYPTIAIATAAAIVASQALISGAYSLTQQAIQLGYSPRVTIRHTSQREIGQIYLPEVNWMLGTACLALVLG
FQTSSRLASAYGIAVTGTMIVTTLLFHRVMRDRWGWARWKAWPLTVLFLTVDAAFFLANVVKFRDGGWFPIAAAALVFTL
MSTWKRGRDALALMLKDAGLPLDLFMADVARRKVQRVAGTAVFMTSNPGGVPPVLLHHLKHNKVLHERVVLVSILAHEIP
FVNEPERVNARELGSGFFQVIAHYGFMETPDVPALLDSLPRRELAGPRLTIVPMETTYFLGRETLLANGPSTIPTWRKRL
FIVMARNAQTASAFFGLPPNRVVEMGAQIQL

Sequences:

>Translated_671_residues
MSQIPSPNDPASTGAAPSSAAVPAGPSATPAPSPTAGFSLPGHRPPPSGKALAALAVGALGVVYGDIGTSPLYSLKECFG
GPHGVRPTDANVLGVLSLVFWAMTFVVTFKYMSFVMRADNRGEGGILALMALVGKTETTRLGRRMLLMLGLFGAALLYGD
GIITPAISVLGAVEGVAVAAPAMERAVVPATVVILVFLFLFQKQGTAKVGAVFGPVMLVWFATIAVLGVRGILHDPTILR
ALLPTHGLSFFARNGWHGFLVLGGVVLVITGGEALYADMGHFGKRPIRVAWLGLAMPALLLNYLGQGALLLHDPGAARNP
FYLLAPEWALYPTIAIATAAAIVASQALISGAYSLTQQAIQLGYSPRVTIRHTSQREIGQIYLPEVNWMLGTACLALVLG
FQTSSRLASAYGIAVTGTMIVTTLLFHRVMRDRWGWARWKAWPLTVLFLTVDAAFFLANVVKFRDGGWFPIAAAALVFTL
MSTWKRGRDALALMLKDAGLPLDLFMADVARRKVQRVAGTAVFMTSNPGGVPPVLLHHLKHNKVLHERVVLVSILAHEIP
FVNEPERVNARELGSGFFQVIAHYGFMETPDVPALLDSLPRRELAGPRLTIVPMETTYFLGRETLLANGPSTIPTWRKRL
FIVMARNAQTASAFFGLPPNRVVEMGAQIQL
>Mature_670_residues
SQIPSPNDPASTGAAPSSAAVPAGPSATPAPSPTAGFSLPGHRPPPSGKALAALAVGALGVVYGDIGTSPLYSLKECFGG
PHGVRPTDANVLGVLSLVFWAMTFVVTFKYMSFVMRADNRGEGGILALMALVGKTETTRLGRRMLLMLGLFGAALLYGDG
IITPAISVLGAVEGVAVAAPAMERAVVPATVVILVFLFLFQKQGTAKVGAVFGPVMLVWFATIAVLGVRGILHDPTILRA
LLPTHGLSFFARNGWHGFLVLGGVVLVITGGEALYADMGHFGKRPIRVAWLGLAMPALLLNYLGQGALLLHDPGAARNPF
YLLAPEWALYPTIAIATAAAIVASQALISGAYSLTQQAIQLGYSPRVTIRHTSQREIGQIYLPEVNWMLGTACLALVLGF
QTSSRLASAYGIAVTGTMIVTTLLFHRVMRDRWGWARWKAWPLTVLFLTVDAAFFLANVVKFRDGGWFPIAAAALVFTLM
STWKRGRDALALMLKDAGLPLDLFMADVARRKVQRVAGTAVFMTSNPGGVPPVLLHHLKHNKVLHERVVLVSILAHEIPF
VNEPERVNARELGSGFFQVIAHYGFMETPDVPALLDSLPRRELAGPRLTIVPMETTYFLGRETLLANGPSTIPTWRKRLF
IVMARNAQTASAFFGLPPNRVVEMGAQIQL

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=624, Percent_Identity=46.3141025641026, Blast_Score=573, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_ANAD2 (B8JF01)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002491424.1
- GeneID:   7297053
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_1007
- HOGENOM:   HBG351154
- ProtClustDB:   CLSK945363
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 71841; Mature: 71709

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x40bf9c38)-; HASH(0x1b37e28c)-; HASH(0x1ab019ec)-; HASH(0x1b0177d0)-; HASH(0x1ac51c68)-; HASH(0x1b37e1e4)-; HASH(0x1147b898)-; HASH(0x1a649490)-; HASH(0x19dbe6cc)-; HASH(0x1b38b408)-; HASH(0x1afcb17c)-; HASH(0x1b37e0e8)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIPSPNDPASTGAAPSSAAVPAGPSATPAPSPTAGFSLPGHRPPPSGKALAALAVGAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GVVYGDIGTSPLYSLKECFGGPHGVRPTDANVLGVLSLVFWAMTFVVTFKYMSFVMRADN
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGEGGILALMALVGKTETTRLGRRMLLMLGLFGAALLYGDGIITPAISVLGAVEGVAVAA
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCC
PAMERAVVPATVVILVFLFLFQKQGTAKVGAVFGPVMLVWFATIAVLGVRGILHDPTILR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLPTHGLSFFARNGWHGFLVLGGVVLVITGGEALYADMGHFGKRPIRVAWLGLAMPALL
HHHHHCCHHHHHCCCCCHHEEECCEEEEEECCCHHHHHHHHCCCCCCEEHHHHHHHHHHH
LNYLGQGALLLHDPGAARNPFYLLAPEWALYPTIAIATAAAIVASQALISGAYSLTQQAI
HHHHCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGYSPRVTIRHTSQREIGQIYLPEVNWMLGTACLALVLGFQTSSRLASAYGIAVTGTMI
HCCCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VTTLLFHRVMRDRWGWARWKAWPLTVLFLTVDAAFFLANVVKFRDGGWFPIAAAALVFTL
HHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MSTWKRGRDALALMLKDAGLPLDLFMADVARRKVQRVAGTAVFMTSNPGGVPPVLLHHLK
HHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHH
HNKVLHERVVLVSILAHEIPFVNEPERVNARELGSGFFQVIAHYGFMETPDVPALLDSLP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
RRELAGPRLTIVPMETTYFLGRETLLANGPSTIPTWRKRLFIVMARNAQTASAFFGLPPN
HHHHCCCEEEEEEECHHHHHCCHHEECCCCCCCHHHHHEEEEEEECCCCCHHHHCCCCHH
RVVEMGAQIQL
HHHHCCCCCCH
>Mature Secondary Structure 
SQIPSPNDPASTGAAPSSAAVPAGPSATPAPSPTAGFSLPGHRPPPSGKALAALAVGAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GVVYGDIGTSPLYSLKECFGGPHGVRPTDANVLGVLSLVFWAMTFVVTFKYMSFVMRADN
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGEGGILALMALVGKTETTRLGRRMLLMLGLFGAALLYGDGIITPAISVLGAVEGVAVAA
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCC
PAMERAVVPATVVILVFLFLFQKQGTAKVGAVFGPVMLVWFATIAVLGVRGILHDPTILR
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLPTHGLSFFARNGWHGFLVLGGVVLVITGGEALYADMGHFGKRPIRVAWLGLAMPALL
HHHHHCCHHHHHCCCCCHHEEECCEEEEEECCCHHHHHHHHCCCCCCEEHHHHHHHHHHH
LNYLGQGALLLHDPGAARNPFYLLAPEWALYPTIAIATAAAIVASQALISGAYSLTQQAI
HHHHCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGYSPRVTIRHTSQREIGQIYLPEVNWMLGTACLALVLGFQTSSRLASAYGIAVTGTMI
HCCCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VTTLLFHRVMRDRWGWARWKAWPLTVLFLTVDAAFFLANVVKFRDGGWFPIAAAALVFTL
HHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MSTWKRGRDALALMLKDAGLPLDLFMADVARRKVQRVAGTAVFMTSNPGGVPPVLLHHLK
HHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHH
HNKVLHERVVLVSILAHEIPFVNEPERVNARELGSGFFQVIAHYGFMETPDVPALLDSLP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
RRELAGPRLTIVPMETTYFLGRETLLANGPSTIPTWRKRLFIVMARNAQTASAFFGLPPN
HHHHCCCEEEEEEECHHHHHCCHHEECCCCCCCHHHHHEEEEEEECCCCCHHHHCCCCHH
RVVEMGAQIQL
HHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA