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The map label for this gene is 220915893

Identifier: 220915893

GI number: 220915893

Start: 874421

End: 874834

Strand: Direct

Name: 220915893

Synonym: A2cp1_0777

Alternate gene names: NA

Gene position: 874421-874834 (Clockwise)

Preceding gene: 220915892

Following gene: 220915894

Centisome position: 17.39

GC content: 67.63

Gene sequence:

>414_bases
ATGGCCTTCCGCATCCGCCAGCCGGTCCGCCACCCCGACGTCGATCGCGCCGGGATCGTGTACTTCCCGCGCTTCTACGA
CTTCTTCCACCGCGCGCTGGAGGACTTCTTCACCGCCGAGGTCGGGATCCCGTTCTGGGATCTCGGCGACCAGCTCAAGG
TCGCGCTGCCGGTGGTGCGCATCGAGACCGACTTCGAGAAGCCGCTGCAGCACGGCGACGCGGTGACGATCCAGCTCACC
ACGCTGCACATCGGCGCGCACTCGATCTCGATCCGCTACGACGTCTTCCGGCCGAACGAGGCCGAGACCGCCGCGAGCTC
GACGATCGTGCTCTGCTGCATCGAGGTGCCCGCCTGGAAGAAGGCGCCCATCCCGCCGGAGATCCGGGCGGCGTTCGAGA
AGCATCGGGTGTAG

Upstream 100 bases:

>100_bases
GAGACGCTGCTCGCCTTCCGCGCGTTCAAGCCGCTCGCCTGACCCCGCCACCCGCAGCGTCCAGATCGCCCGCATCGCCG
ACACGAGGAGACGAGGAGCC

Downstream 100 bases:

>100_bases
GGGCGCGCGGCGCCAGTTGTCGCGGGGCGGAGCTGACCCGGGCGCGGTTCTCACTTCCCGTCACATCGGGGAAACCGCAC
GTTCCACGCTCACCGGGAGG

Product: thioesterase superfamily protein

Products: NA

Alternate protein names: DHNA-CoA hydrolase; DHNA-CoA thioesterase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MAFRIRQPVRHPDVDRAGIVYFPRFYDFFHRALEDFFTAEVGIPFWDLGDQLKVALPVVRIETDFEKPLQHGDAVTIQLT
TLHIGAHSISIRYDVFRPNEAETAASSTIVLCCIEVPAWKKAPIPPEIRAAFEKHRV

Sequences:

>Translated_137_residues
MAFRIRQPVRHPDVDRAGIVYFPRFYDFFHRALEDFFTAEVGIPFWDLGDQLKVALPVVRIETDFEKPLQHGDAVTIQLT
TLHIGAHSISIRYDVFRPNEAETAASSTIVLCCIEVPAWKKAPIPPEIRAAFEKHRV
>Mature_136_residues
AFRIRQPVRHPDVDRAGIVYFPRFYDFFHRALEDFFTAEVGIPFWDLGDQLKVALPVVRIETDFEKPLQHGDAVTIQLTT
LHIGAHSISIRYDVFRPNEAETAASSTIVLCCIEVPAWKKAPIPPEIRAAFEKHRV

Specific function: Catalyzes the specific hydrolysis of 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis. Is not active on benzoyl-CoA, phenylacetyl-CoA and aliphatic acyl-CoA thio

COG id: COG0824

COG function: function code R; Predicted thioesterase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022829
- InterPro:   IPR008272
- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: =3.1.2.28 [H]

Molecular weight: Translated: 15700; Mature: 15569

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRIRQPVRHPDVDRAGIVYFPRFYDFFHRALEDFFTAEVGIPFWDLGDQLKVALPVVR
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEEEE
IETDFEKPLQHGDAVTIQLTTLHIGAHSISIRYDVFRPNEAETAASSTIVLCCIEVPAWK
EECCCHHHHHCCCEEEEEEEEEEECCEEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCC
KAPIPPEIRAAFEKHRV
CCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AFRIRQPVRHPDVDRAGIVYFPRFYDFFHRALEDFFTAEVGIPFWDLGDQLKVALPVVR
CCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEEEE
IETDFEKPLQHGDAVTIQLTTLHIGAHSISIRYDVFRPNEAETAASSTIVLCCIEVPAWK
EECCCHHHHHCCCEEEEEEEEEEECCEEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCC
KAPIPPEIRAAFEKHRV
CCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]