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The map label for this gene is pilD [H]

Identifier: 220915790

GI number: 220915790

Start: 750634

End: 751533

Strand: Direct

Name: pilD [H]

Synonym: A2cp1_0671

Alternate gene names: 220915790

Gene position: 750634-751533 (Clockwise)

Preceding gene: 220915789

Following gene: 220915791

Centisome position: 14.93

GC content: 76.67

Gene sequence:

>900_bases
ATGGATCCCGCGGCGCCCGGCGTCCCCGCGGGCCTGGTGGCGGCCTGGGTCGCGCTGGTCGGCGGCGTGGTGGGCAGCTT
CCTCAACGTCGTGATCGCCCGCGTCCCCGCGGGCGAGTCGATCGTCTCGCCGGGCTCGCGCTGCCCGCGCTGCCGGACGC
CCATCGCCTGGTACGACAACGTGCCGGTGGTGTCCTGGCTCGCGCTGCGCGCGCGGTGCCGGAGCTGCGGCGTGCGGATC
TCCGCCCGCTACCCGCTGGTCGAGGCGCTCGTCGCTGGCGTGGCGCTGCTGGCGTGGGCGCGTCACGGCCTCGCCGTCGC
TGCGCTGGGCGAGCTGGTGCTGGTCTCGCTCCTGGTGGCGCTCGCGTTCATCGACCTCGACACCTGGCTGCTGCCGCACG
CGCTCACCTGGCCGCTCATCGCCACCGGCCTCGCCGTGTCCGCGGCCGGCCTCGGGCCGGCGACGCTGCAGGGGGCGGCC
ATCGGCGCCGCGGTCGGCTTCGGCGCCTTCGCGCTGGTTTCGGTCGTGGGCGAGAAGGTGCTGCGGAAGGAGGCGCTCGG
CTTCGGCGACGTCTGGCTCCTCTCCGGGATCGGCGCCTGGATGGGCGTGGCGGCGCTGCTCCCGGTGGTGCTGCTCGCCT
CGGTGCAGGGGAGCGTGGTGGGCCTGGTGCTGCTCGCGCTCGGCAAGGGGCAGCCGGGTCCCGGGCAGCCGGCCGAGGCC
GCCGGGCCGCCCGCGGCGGCCGTGCCGGGAGATCCGGCCGCGCTCGCCAGCGCGGACGACTGGATCCCTCCCCGGAACGC
GGTCCCGTTCGGCCCGTTCCTGGCGGCCGGGGCGCTGGAGTGGCTGTACCTGGGGGACCTCATCGTGCGCGGCGTCCCCT
CCCTCGGCATCTTCCGGTGA

Upstream 100 bases:

>100_bases
CGCCGCACCGCGACACCCTCGAGGACTTCTTCGTCCGCCGCCTGACCGAGGTGCACGGCGCGGAGGCGGAGCCGGCGGCA
GCCGCCGGAGGCGCCTAGGC

Downstream 100 bases:

>100_bases
TCGATGCGGCGCGTGGGCCTGGTGCTCCTGCTCGATCTCGTCGCCGCCGCGGCGGCGGGCGCGACGCTCCTGCTCGCGCT
GGGGGTTCCCTCCGCGGCCC

Product: peptidase A24A domain-containing protein

Products: NA

Alternate protein names: Leader peptidase; Prepilin peptidase; N-methyltransferase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDPAAPGVPAGLVAAWVALVGGVVGSFLNVVIARVPAGESIVSPGSRCPRCRTPIAWYDNVPVVSWLALRARCRSCGVRI
SARYPLVEALVAGVALLAWARHGLAVAALGELVLVSLLVALAFIDLDTWLLPHALTWPLIATGLAVSAAGLGPATLQGAA
IGAAVGFGAFALVSVVGEKVLRKEALGFGDVWLLSGIGAWMGVAALLPVVLLASVQGSVVGLVLLALGKGQPGPGQPAEA
AGPPAAAVPGDPAALASADDWIPPRNAVPFGPFLAAGALEWLYLGDLIVRGVPSLGIFR

Sequences:

>Translated_299_residues
MDPAAPGVPAGLVAAWVALVGGVVGSFLNVVIARVPAGESIVSPGSRCPRCRTPIAWYDNVPVVSWLALRARCRSCGVRI
SARYPLVEALVAGVALLAWARHGLAVAALGELVLVSLLVALAFIDLDTWLLPHALTWPLIATGLAVSAAGLGPATLQGAA
IGAAVGFGAFALVSVVGEKVLRKEALGFGDVWLLSGIGAWMGVAALLPVVLLASVQGSVVGLVLLALGKGQPGPGQPAEA
AGPPAAAVPGDPAALASADDWIPPRNAVPFGPFLAAGALEWLYLGDLIVRGVPSLGIFR
>Mature_299_residues
MDPAAPGVPAGLVAAWVALVGGVVGSFLNVVIARVPAGESIVSPGSRCPRCRTPIAWYDNVPVVSWLALRARCRSCGVRI
SARYPLVEALVAGVALLAWARHGLAVAALGELVLVSLLVALAFIDLDTWLLPHALTWPLIATGLAVSAAGLGPATLQGAA
IGAAVGFGAFALVSVVGEKVLRKEALGFGDVWLLSGIGAWMGVAALLPVVLLASVQGSVVGLVLLALGKGQPGPGQPAEA
AGPPAAAVPGDPAALASADDWIPPRNAVPFGPFLAAGALEWLYLGDLIVRGVPSLGIFR

Specific function: Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue [H]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI87082194, Length=229, Percent_Identity=41.4847161572052, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010627
- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06750 DiS_P_DiS; PF01478 Peptidase_A24 [H]

EC number: =3.4.23.43 [H]

Molecular weight: Translated: 30141; Mature: 30141

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPAAPGVPAGLVAAWVALVGGVVGSFLNVVIARVPAGESIVSPGSRCPRCRTPIAWYDN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCC
VPVVSWLALRARCRSCGVRISARYPLVEALVAGVALLAWARHGLAVAALGELVLVSLLVA
CHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LAFIDLDTWLLPHALTWPLIATGLAVSAAGLGPATLQGAAIGAAVGFGAFALVSVVGEKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRKEALGFGDVWLLSGIGAWMGVAALLPVVLLASVQGSVVGLVLLALGKGQPGPGQPAEA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCC
AGPPAAAVPGDPAALASADDWIPPRNAVPFGPFLAAGALEWLYLGDLIVRGVPSLGIFR
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDPAAPGVPAGLVAAWVALVGGVVGSFLNVVIARVPAGESIVSPGSRCPRCRTPIAWYDN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCC
VPVVSWLALRARCRSCGVRISARYPLVEALVAGVALLAWARHGLAVAALGELVLVSLLVA
CHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LAFIDLDTWLLPHALTWPLIATGLAVSAAGLGPATLQGAAIGAAVGFGAFALVSVVGEKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRKEALGFGDVWLLSGIGAWMGVAALLPVVLLASVQGSVVGLVLLALGKGQPGPGQPAEA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCC
AGPPAAAVPGDPAALASADDWIPPRNAVPFGPFLAAGALEWLYLGDLIVRGVPSLGIFR
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA