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The map label for this gene is pyrH [H]

Identifier: 220915423

GI number: 220915423

Start: 338149

End: 338904

Strand: Direct

Name: pyrH [H]

Synonym: A2cp1_0302

Alternate gene names: 220915423

Gene position: 338149-338904 (Clockwise)

Preceding gene: 220915422

Following gene: 220915424

Centisome position: 6.72

GC content: 66.93

Gene sequence:

>756_bases
ATGGCGAGCGAGAAAGCCTCCAACGCGAAGGCCCGTTACCAGCGCATCCTGCTCAAGCTCTCGGGCGAGGCGCTCATGGG
GGACGGCAAGTACGGCATCTCGCCGAAGACCCTCACCTCCATCGCCCACGACGTGAAGGACGTGGTGGACCTCGGGGTCG
AGGTCGCGCTCACCATCGGCGGCGGCAACATCTTCCGCGGCGTGTCGGGCGCGACCGAGGGGATGGACCGCTCCTCGGCC
GACTACATGGGCATGCTCGCGACCGTCATCAACTCGATGGCGCTGCAGGACGCGCTCGAGAAGATCGGCGTGCCCACCCG
CGTGCAGTCCGCGATCGAGATGCACCAGGTCGCCGAGCCGTACATCCGCCGCCGCGCCATCCGCCACCTGGAGAAGGGGC
GGGTGGTGATCTTCGCCGCCGGCACCGGCAACCCGTACTTCACCACCGACACCGCCGCCTCGCTCCGCGCCATGGAGATC
CACGCGGACGTGCTGCTCAAGGCGACCAAGGTGGACGGCGTCTACACCGACGACCCGAAGAAGAACCCGGCGGCGACCAA
GTTCAAGCAGCTCAGCTACATCGACGTGCTGAAGAAGAACCTCAAGGTGATGGACTCCACCGCCATCAGCCTCTGCATGG
ACAACGACCTCCCCATCGTCGTGTTCGACCTCACCCAGCGCGGGAACGTGCGCAAGGTGGTGCTCGGCGAGGAGATCGGC
ACCACCGTCGGGCGCCCCAGCGCCAGGAACGCGTAG

Upstream 100 bases:

>100_bases
CGCCCGCCGAGGCTGGCGGGCAGGGGTGAGCGCGCGCGGGAATCCTCCGCAACACCGCCGCCTTGACCGACCCCACCGCA
CCCGGTACAACCCGCCGACC

Downstream 100 bases:

>100_bases
CCTCGGCAAGGAGACGGCCATGGGCACCATCGCAGACGACATCCTCGACGACCTGCACGGGCGCATCCTCAAGACGCTCG
ACCAGCTCCGGACCGAGCTC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MASEKASNAKARYQRILLKLSGEALMGDGKYGISPKTLTSIAHDVKDVVDLGVEVALTIGGGNIFRGVSGATEGMDRSSA
DYMGMLATVINSMALQDALEKIGVPTRVQSAIEMHQVAEPYIRRRAIRHLEKGRVVIFAAGTGNPYFTTDTAASLRAMEI
HADVLLKATKVDGVYTDDPKKNPAATKFKQLSYIDVLKKNLKVMDSTAISLCMDNDLPIVVFDLTQRGNVRKVVLGEEIG
TTVGRPSARNA

Sequences:

>Translated_251_residues
MASEKASNAKARYQRILLKLSGEALMGDGKYGISPKTLTSIAHDVKDVVDLGVEVALTIGGGNIFRGVSGATEGMDRSSA
DYMGMLATVINSMALQDALEKIGVPTRVQSAIEMHQVAEPYIRRRAIRHLEKGRVVIFAAGTGNPYFTTDTAASLRAMEI
HADVLLKATKVDGVYTDDPKKNPAATKFKQLSYIDVLKKNLKVMDSTAISLCMDNDLPIVVFDLTQRGNVRKVVLGEEIG
TTVGRPSARNA
>Mature_250_residues
ASEKASNAKARYQRILLKLSGEALMGDGKYGISPKTLTSIAHDVKDVVDLGVEVALTIGGGNIFRGVSGATEGMDRSSAD
YMGMLATVINSMALQDALEKIGVPTRVQSAIEMHQVAEPYIRRRAIRHLEKGRVVIFAAGTGNPYFTTDTAASLRAMEIH
ADVLLKATKVDGVYTDDPKKNPAATKFKQLSYIDVLKKNLKVMDSTAISLCMDNDLPIVVFDLTQRGNVRKVVLGEEIGT
TVGRPSARNA

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=238, Percent_Identity=53.3613445378151, Blast_Score=256, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27069; Mature: 26937

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEKASNAKARYQRILLKLSGEALMGDGKYGISPKTLTSIAHDVKDVVDLGVEVALTIG
CCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEC
GGNIFRGVSGATEGMDRSSADYMGMLATVINSMALQDALEKIGVPTRVQSAIEMHQVAEP
CCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YIRRRAIRHLEKGRVVIFAAGTGNPYFTTDTAASLRAMEIHADVLLKATKVDGVYTDDPK
HHHHHHHHHHHCCCEEEEEECCCCCEEECCHHHHHHHHEEHHHHHEEEEECCCEECCCCC
KNPAATKFKQLSYIDVLKKNLKVMDSTAISLCMDNDLPIVVFDLTQRGNVRKVVLGEEIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCEEEEEECCHHC
TTVGRPSARNA
CCCCCCCCCCC
>Mature Secondary Structure 
ASEKASNAKARYQRILLKLSGEALMGDGKYGISPKTLTSIAHDVKDVVDLGVEVALTIG
CCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEC
GGNIFRGVSGATEGMDRSSADYMGMLATVINSMALQDALEKIGVPTRVQSAIEMHQVAEP
CCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YIRRRAIRHLEKGRVVIFAAGTGNPYFTTDTAASLRAMEIHADVLLKATKVDGVYTDDPK
HHHHHHHHHHHCCCEEEEEECCCCCEEECCHHHHHHHHEEHHHHHEEEEECCCEECCCCC
KNPAATKFKQLSYIDVLKKNLKVMDSTAISLCMDNDLPIVVFDLTQRGNVRKVVLGEEIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCEEEEEECCHHC
TTVGRPSARNA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA