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The map label for this gene is frr

Identifier: 220915424

GI number: 220915424

Start: 338924

End: 339490

Strand: Direct

Name: frr

Synonym: A2cp1_0303

Alternate gene names: 220915424

Gene position: 338924-339490 (Clockwise)

Preceding gene: 220915423

Following gene: 220915425

Centisome position: 6.74

GC content: 66.84

Gene sequence:

>567_bases
ATGGGCACCATCGCAGACGACATCCTCGACGACCTGCACGGGCGCATCCTCAAGACGCTCGACCAGCTCCGGACCGAGCT
CGCCGCGGTCCGCACCGGGCGCGCCTCGCTCCACCTGCTCGACAACGTCCGGGTGGACTACTACGGCACGCCCACCCCGC
TGAACCAGGTGGCGACGCTGTCCGTGCCCGAGGCGCGGCTCATCGTGGTGAAGCCCTGGGAGAAGTCGATGATCCCGCCG
ATCGAGAAGGCGATCCGCGACGGGAACCTCGGCCTCAACCCCATGAGCGACAAGGACCTCGTCCGCGTCCCGATCCCCGC
GCTCACCGAGGAGCGCCGCAAGGAGATCGTGAAGCAGGTGAAGCACAAGGGCGAGGAGCACAAGATCGCCGTCCGCAACG
TGCGCCGCGAGGCGAAGGAGCTGATCGAGGTCGCGGAGAAGGACGGCGACATCTCGGGCGACGACGCCGAGAAGGCGCTC
GAGAAGATGCAGAAGGAGACCGACGACGGCGTGAAGAAGATCGACGAGATCGTCGCCGCCAAGGAGAAGGACGTCCTCCA
GGTCTGA

Upstream 100 bases:

>100_bases
CAGCGCGGGAACGTGCGCAAGGTGGTGCTCGGCGAGGAGATCGGCACCACCGTCGGGCGCCCCAGCGCCAGGAACGCGTA
GCCTCGGCAAGGAGACGGCC

Downstream 100 bases:

>100_bases
TGGGCGGCGCCGTGGCCCGCTCCCCCGCCGCGCTGCTCCTGCTCCTCGGCCCGCTGCTCGCGCTCGGCTTCGCCGCCGGC
GCGGTCCGCGCGCTGGCCGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MGTIADDILDDLHGRILKTLDQLRTELAAVRTGRASLHLLDNVRVDYYGTPTPLNQVATLSVPEARLIVVKPWEKSMIPP
IEKAIRDGNLGLNPMSDKDLVRVPIPALTEERRKEIVKQVKHKGEEHKIAVRNVRREAKELIEVAEKDGDISGDDAEKAL
EKMQKETDDGVKKIDEIVAAKEKDVLQV

Sequences:

>Translated_188_residues
MGTIADDILDDLHGRILKTLDQLRTELAAVRTGRASLHLLDNVRVDYYGTPTPLNQVATLSVPEARLIVVKPWEKSMIPP
IEKAIRDGNLGLNPMSDKDLVRVPIPALTEERRKEIVKQVKHKGEEHKIAVRNVRREAKELIEVAEKDGDISGDDAEKAL
EKMQKETDDGVKKIDEIVAAKEKDVLQV
>Mature_187_residues
GTIADDILDDLHGRILKTLDQLRTELAAVRTGRASLHLLDNVRVDYYGTPTPLNQVATLSVPEARLIVVKPWEKSMIPPI
EKAIRDGNLGLNPMSDKDLVRVPIPALTEERRKEIVKQVKHKGEEHKIAVRNVRREAKELIEVAEKDGDISGDDAEKALE
KMQKETDDGVKKIDEIVAAKEKDVLQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=43.956043956044, Blast_Score=159, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24661488, Length=179, Percent_Identity=25.6983240223464, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_ANAD2 (B8J9V9)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002490728.1
- ProteinModelPortal:   B8J9V9
- SMR:   B8J9V9
- GeneID:   7299005
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_0303
- HOGENOM:   HBG533975
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21052; Mature: 20920

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTIADDILDDLHGRILKTLDQLRTELAAVRTGRASLHLLDNVRVDYYGTPTPLNQVATL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHCCCEEEECCCCCCHHHEEEC
SVPEARLIVVKPWEKSMIPPIEKAIRDGNLGLNPMSDKDLVRVPIPALTEERRKEIVKQV
CCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
KHKGEEHKIAVRNVRREAKELIEVAEKDGDISGDDAEKALEKMQKETDDGVKKIDEIVAA
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KEKDVLQV
CCHHHCCC
>Mature Secondary Structure 
GTIADDILDDLHGRILKTLDQLRTELAAVRTGRASLHLLDNVRVDYYGTPTPLNQVATL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHCCCEEEECCCCCCHHHEEEC
SVPEARLIVVKPWEKSMIPPIEKAIRDGNLGLNPMSDKDLVRVPIPALTEERRKEIVKQV
CCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHH
KHKGEEHKIAVRNVRREAKELIEVAEKDGDISGDDAEKALEKMQKETDDGVKKIDEIVAA
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KEKDVLQV
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA