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The map label for this gene is 220915377

Identifier: 220915377

GI number: 220915377

Start: 276722

End: 279328

Strand: Direct

Name: 220915377

Synonym: A2cp1_0256

Alternate gene names: NA

Gene position: 276722-279328 (Clockwise)

Preceding gene: 220915376

Following gene: 220915378

Centisome position: 5.5

GC content: 76.45

Gene sequence:

>2607_bases
ATGACGCGCCTCCGCACGCCCGCCGCGCTCGCCCTGTCCCTCGCCGCCCTCGCCTGCGGCGGCGGCGGGAGCGACTCGCC
GCCGCTGCCCACCGCCTTCACGCTGTCCGGCCACATCGCGGCCACCGCCGGGCAGGACGTGGACCGGGACGTGGCGGACA
CGTCGACCACGCGGACGCCCAACGACTCGGCCGCGCAGGCGCAGCCGCTCGCGTCGGTGACCACGCTGGGCGGCTGGGCC
AGCGCGGCGGCCGGCGCCTACGACACGGGGCTCCCCTACCCGGCGGATCCGCAGGACTGGTACCGGGCCACCCTCGAGGC
AGGGCAGACCGTGGTGCTGGAGGTCGCCGACACCGCCGCCACGTTCGAGCTCTGCCTGTTCTCCGCCGACGGCACGACCA
GCATCTCCTGCGCCAGCTCGGGCACGGGGACGCCGGTGCTCACGGTGCCCGCGGCCGCCACCTACCTCGTCCGCGTCCGC
GCGGCGAGCGGCCTCTCCAACTACGCGCTCACCCTGGGCGTGAACGGCGCTGCGGCGGTCGCCGGCGCGGCGCCGCACCT
GGCGCTCCCGTTCGTGCCCGGGGAGCTGGTGGTCCGCTTCCGCGACGACACACTCGGGGTCGCCGCCGCCGGCGACCTGC
GGCAGCGCGCCGCCGCGCTGGGCCTCACCGCGCTGGCGGGCGCCCGCGGCCGGGCCGCGCTGCTCTCCATGTCCGGCCCC
GAGGCGCGCGCGCGCGCCCTCGCCGCGCTCGGCGTCGAGCCGCTCGCGCCGGATGCGCTCGGCGCCGGCGCCGATCCGGT
GCTGGCCGAGAAGTGGGACACGCTCCGCGCCATCGCGGCGCTGCGCCGCCGGGCCGACGTGGAGAGCGCCGATCCCAACT
TCGTGTTCCAGCCGGCGAGGGTCCCGACCGACACGTACTACAAGTACCAGTGGCACTACCCGCTCATCTCGCTGCCGCAG
GCCTGGGACGTCACCACGGGCGTCGCGGGCGCGGTGGTGGCGGTGGTGGACACCGGCGTGTTCCTCGCGCACCCCGACCT
CTCCGGCCAGCTCGTGACCGGCTACGACTTCATCCGCGATCCCACCATGGCGAACGACGGGAACGGCATCGATCCGAACC
CGGACGACCCGGGCGACGCGGCCACGCCGGGCGGCAGCTCCTGGCACGGCACCCACGTCGCGGGCACGGTGGCCGCGCGC
GCGGACGGCTCGGGCGTGGTGGGCGTGGCGTGGGACGCGCGGGTGATGCCGCTCCGCGCGCTCGGCGTGGGCGGCGGGAC
CTCCTACGACATCGTGCAGGCGGTGAGCTACGCGGCCGGCCTCGCCAACGACTCCGGCACGGTTCCGGCCACGCGGGCCG
CGGTGGTCAACCTGAGCCTCGGCTGCCAGGGCTGCTTCTCGTCCACCGAGCAGGCCGTCTACAACGCCGCGCGCAACGCG
GGGGTCATCGTGGTCGCCGCGGCGGGCAACGAGGCGTCGTCCGCGCCGGGCTACCCGGCCGCGTACGCGGGCGTGCTCTC
GGTGAGCGCGGTCGACATGAAGGGCGCGAAGGCGCCGTACTCGAACACCGGCAGCACCGTGGACCTCGCCGCGCCGGGCG
GCAACACCGCGGTGGACCTCGACGGGAACGGCTACGCCGACGGCGTGCTCTCCACGCTCGTGAAGGACACCACCGGCACC
CGCGAGCCCATCTACGCGTTCTACCAGGGCACCTCGATGGCCGCGCCGCACGTGGCCGGCGTCATGGCGCTCGTGAAGTC
GGTCTGCCCGAGCCTTGCCCCCGCGGCGGTGGATCAGCTGCTGCAGGAGGGACAGCTCACCCGCGACCTCGGGACGCCCG
GCCGCGACGACACGTTCGGCTGGGGCCTCGTCGACGCGCTGAAGGCGGTGCAGGCGGCAGCGACGAGCTGCGGCGCGCCG
CTGCCGCCCTCGCTGTCGGTGACCCCGGGGCGGCTCGACTTCGGGCCGGCCGACGCCACGCTGCAGCTCCAGGCGGCGAA
GGTGGGCGAGGGCGCGCTCACCGTGACCGCGGTCTCCGACGACGCCGCCTGGCTCACCGTCACGGCGCCCGGCGTGGACG
CGAGCGGCCTCGGCGCGTACGCCGCCGCCGTGGACCGGACCGGCCTCGCCGACGGCCGCTACGCCGCCAAGATCACCTTC
ACGCCGTCGGTGGGTGACCCGGTGGTCATCCCGGTGACGCTGCAGGTCGGCGCCGCCGCGGCGGCCGGCGACGCCGGCTA
CCTCTACGCGCTGCTCGTCCGCGAGGGCGTGAGCGGCCCGGAGCTCGTGAAGCAGTGGAGCGGCGCGGCGTCGGGCGGCA
GCTACGCCTTCCGCTTCGACGGCGTCTCCGCGGGCACCTACTACCTCGTGGCCGGCAGCGACATGAACAACGACGGCTAC
ATCTGCGACGCGGGCGAGTCCTGCGGCGCCTGGCCGACGCTGGGCGTCCTCACGCCGCTCGGCGCGAGCGGCCCGCGCTC
CGACCTCGACTTCAGCGTCGCGTTCGACCCGGCCGTCGCCCCGGTGGGCGCGGCCGCGGGCGCGCCGGTGGGCGCCCGGG
GCCTGGCGCGGCAGCCGGCGACGAAGGGCGTGGCCGGGCTGCGCTAG

Upstream 100 bases:

>100_bases
GCCCCGCGCCCGCGGGCCCCGCGCACCCATGGGTCACGGCGGTGGGCTTGCGCGCCGCCGCCCGCGCTGCGACAACCAGC
CGACCACCTCGGGAGCCCAC

Downstream 100 bases:

>100_bases
CGGCAGGCGGGCGCGCTCCCGGGCCGGGCGGCGTTGCCTCCGGCGCCGCCCGGGCCGATGTTCCTTGAGGCGGAGCGGCC
GGGCACCTAACATCTCCGGT

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 868; Mature: 867

Protein sequence:

>868_residues
MTRLRTPAALALSLAALACGGGGSDSPPLPTAFTLSGHIAATAGQDVDRDVADTSTTRTPNDSAAQAQPLASVTTLGGWA
SAAAGAYDTGLPYPADPQDWYRATLEAGQTVVLEVADTAATFELCLFSADGTTSISCASSGTGTPVLTVPAAATYLVRVR
AASGLSNYALTLGVNGAAAVAGAAPHLALPFVPGELVVRFRDDTLGVAAAGDLRQRAAALGLTALAGARGRAALLSMSGP
EARARALAALGVEPLAPDALGAGADPVLAEKWDTLRAIAALRRRADVESADPNFVFQPARVPTDTYYKYQWHYPLISLPQ
AWDVTTGVAGAVVAVVDTGVFLAHPDLSGQLVTGYDFIRDPTMANDGNGIDPNPDDPGDAATPGGSSWHGTHVAGTVAAR
ADGSGVVGVAWDARVMPLRALGVGGGTSYDIVQAVSYAAGLANDSGTVPATRAAVVNLSLGCQGCFSSTEQAVYNAARNA
GVIVVAAAGNEASSAPGYPAAYAGVLSVSAVDMKGAKAPYSNTGSTVDLAAPGGNTAVDLDGNGYADGVLSTLVKDTTGT
REPIYAFYQGTSMAAPHVAGVMALVKSVCPSLAPAAVDQLLQEGQLTRDLGTPGRDDTFGWGLVDALKAVQAAATSCGAP
LPPSLSVTPGRLDFGPADATLQLQAAKVGEGALTVTAVSDDAAWLTVTAPGVDASGLGAYAAAVDRTGLADGRYAAKITF
TPSVGDPVVIPVTLQVGAAAAAGDAGYLYALLVREGVSGPELVKQWSGAASGGSYAFRFDGVSAGTYYLVAGSDMNNDGY
ICDAGESCGAWPTLGVLTPLGASGPRSDLDFSVAFDPAVAPVGAAAGAPVGARGLARQPATKGVAGLR

Sequences:

>Translated_868_residues
MTRLRTPAALALSLAALACGGGGSDSPPLPTAFTLSGHIAATAGQDVDRDVADTSTTRTPNDSAAQAQPLASVTTLGGWA
SAAAGAYDTGLPYPADPQDWYRATLEAGQTVVLEVADTAATFELCLFSADGTTSISCASSGTGTPVLTVPAAATYLVRVR
AASGLSNYALTLGVNGAAAVAGAAPHLALPFVPGELVVRFRDDTLGVAAAGDLRQRAAALGLTALAGARGRAALLSMSGP
EARARALAALGVEPLAPDALGAGADPVLAEKWDTLRAIAALRRRADVESADPNFVFQPARVPTDTYYKYQWHYPLISLPQ
AWDVTTGVAGAVVAVVDTGVFLAHPDLSGQLVTGYDFIRDPTMANDGNGIDPNPDDPGDAATPGGSSWHGTHVAGTVAAR
ADGSGVVGVAWDARVMPLRALGVGGGTSYDIVQAVSYAAGLANDSGTVPATRAAVVNLSLGCQGCFSSTEQAVYNAARNA
GVIVVAAAGNEASSAPGYPAAYAGVLSVSAVDMKGAKAPYSNTGSTVDLAAPGGNTAVDLDGNGYADGVLSTLVKDTTGT
REPIYAFYQGTSMAAPHVAGVMALVKSVCPSLAPAAVDQLLQEGQLTRDLGTPGRDDTFGWGLVDALKAVQAAATSCGAP
LPPSLSVTPGRLDFGPADATLQLQAAKVGEGALTVTAVSDDAAWLTVTAPGVDASGLGAYAAAVDRTGLADGRYAAKITF
TPSVGDPVVIPVTLQVGAAAAAGDAGYLYALLVREGVSGPELVKQWSGAASGGSYAFRFDGVSAGTYYLVAGSDMNNDGY
ICDAGESCGAWPTLGVLTPLGASGPRSDLDFSVAFDPAVAPVGAAAGAPVGARGLARQPATKGVAGLR
>Mature_867_residues
TRLRTPAALALSLAALACGGGGSDSPPLPTAFTLSGHIAATAGQDVDRDVADTSTTRTPNDSAAQAQPLASVTTLGGWAS
AAAGAYDTGLPYPADPQDWYRATLEAGQTVVLEVADTAATFELCLFSADGTTSISCASSGTGTPVLTVPAAATYLVRVRA
ASGLSNYALTLGVNGAAAVAGAAPHLALPFVPGELVVRFRDDTLGVAAAGDLRQRAAALGLTALAGARGRAALLSMSGPE
ARARALAALGVEPLAPDALGAGADPVLAEKWDTLRAIAALRRRADVESADPNFVFQPARVPTDTYYKYQWHYPLISLPQA
WDVTTGVAGAVVAVVDTGVFLAHPDLSGQLVTGYDFIRDPTMANDGNGIDPNPDDPGDAATPGGSSWHGTHVAGTVAARA
DGSGVVGVAWDARVMPLRALGVGGGTSYDIVQAVSYAAGLANDSGTVPATRAAVVNLSLGCQGCFSSTEQAVYNAARNAG
VIVVAAAGNEASSAPGYPAAYAGVLSVSAVDMKGAKAPYSNTGSTVDLAAPGGNTAVDLDGNGYADGVLSTLVKDTTGTR
EPIYAFYQGTSMAAPHVAGVMALVKSVCPSLAPAAVDQLLQEGQLTRDLGTPGRDDTFGWGLVDALKAVQAAATSCGAPL
PPSLSVTPGRLDFGPADATLQLQAAKVGEGALTVTAVSDDAAWLTVTAPGVDASGLGAYAAAVDRTGLADGRYAAKITFT
PSVGDPVVIPVTLQVGAAAAAGDAGYLYALLVREGVSGPELVKQWSGAASGGSYAFRFDGVSAGTYYLVAGSDMNNDGYI
CDAGESCGAWPTLGVLTPLGASGPRSDLDFSVAFDPAVAPVGAAAGAPVGARGLARQPATKGVAGLR

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI76443679, Length=142, Percent_Identity=38.0281690140845, Blast_Score=71, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320775, Length=281, Percent_Identity=30.9608540925267, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324576, Length=266, Percent_Identity=29.3233082706767, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360987, Length=400, Percent_Identity=27, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24642494, Length=400, Percent_Identity=27, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24642490, Length=400, Percent_Identity=27, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45555723, Length=400, Percent_Identity=27, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24642492, Length=400, Percent_Identity=27, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 86647; Mature: 86516

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLRTPAALALSLAALACGGGGSDSPPLPTAFTLSGHIAATAGQDVDRDVADTSTTRTP
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEECCCCCCCCHHHCCCCCCCC
NDSAAQAQPLASVTTLGGWASAAAGAYDTGLPYPADPQDWYRATLEAGQTVVLEVADTAA
CCCCHHHCCCHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCE
TFELCLFSADGTTSISCASSGTGTPVLTVPAAATYLVRVRAASGLSNYALTLGVNGAAAV
EEEEEEEECCCCCEEEECCCCCCCEEEECCCCEEEEEEEEHHCCCCCEEEEEECCCHHHH
AGAAPHLALPFVPGELVVRFRDDTLGVAAAGDLRQRAAALGLTALAGARGRAALLSMSGP
CCCCCCEEECCCCCEEEEEEECCCCCEEECHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
EARARALAALGVEPLAPDALGAGADPVLAEKWDTLRAIAALRRRADVESADPNFVFQPAR
HHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
VPTDTYYKYQWHYPLISLPQAWDVTTGVAGAVVAVVDTGVFLAHPDLSGQLVTGYDFIRD
CCCCCEEEEEEECCCEECCCCCCCCCCHHHHEEEEEECCEEEECCCCCCEEEECHHHHCC
PTMANDGNGIDPNPDDPGDAATPGGSSWHGTHVAGTVAARADGSGVVGVAWDARVMPLRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCEEEEEEE
LGVGGGTSYDIVQAVSYAAGLANDSGTVPATRAAVVNLSLGCQGCFSSTEQAVYNAARNA
EECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCC
GVIVVAAAGNEASSAPGYPAAYAGVLSVSAVDMKGAKAPYSNTGSTVDLAAPGGNTAVDL
CEEEEEECCCCCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEE
DGNGYADGVLSTLVKDTTGTREPIYAFYQGTSMAAPHVAGVMALVKSVCPSLAPAAVDQL
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LQEGQLTRDLGTPGRDDTFGWGLVDALKAVQAAATSCGAPLPPSLSVTPGRLDFGPADAT
HHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCE
LQLQAAKVGEGALTVTAVSDDAAWLTVTAPGVDASGLGAYAAAVDRTGLADGRYAAKITF
EEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEE
TPSVGDPVVIPVTLQVGAAAAAGDAGYLYALLVREGVSGPELVKQWSGAASGGSYAFRFD
CCCCCCCEEEEEEEEECCCCCCCCCHHEEEEHHHCCCCCHHHHHHHCCCCCCCCEEEEEC
GVSAGTYYLVAGSDMNNDGYICDAGESCGAWPTLGVLTPLGASGPRSDLDFSVAFDPAVA
CCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCC
PVGAAAGAPVGARGLARQPATKGVAGLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRLRTPAALALSLAALACGGGGSDSPPLPTAFTLSGHIAATAGQDVDRDVADTSTTRTP
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEECCCCCCCCHHHCCCCCCCC
NDSAAQAQPLASVTTLGGWASAAAGAYDTGLPYPADPQDWYRATLEAGQTVVLEVADTAA
CCCCHHHCCCHHHHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCE
TFELCLFSADGTTSISCASSGTGTPVLTVPAAATYLVRVRAASGLSNYALTLGVNGAAAV
EEEEEEEECCCCCEEEECCCCCCCEEEECCCCEEEEEEEEHHCCCCCEEEEEECCCHHHH
AGAAPHLALPFVPGELVVRFRDDTLGVAAAGDLRQRAAALGLTALAGARGRAALLSMSGP
CCCCCCEEECCCCCEEEEEEECCCCCEEECHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
EARARALAALGVEPLAPDALGAGADPVLAEKWDTLRAIAALRRRADVESADPNFVFQPAR
HHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
VPTDTYYKYQWHYPLISLPQAWDVTTGVAGAVVAVVDTGVFLAHPDLSGQLVTGYDFIRD
CCCCCEEEEEEECCCEECCCCCCCCCCHHHHEEEEEECCEEEECCCCCCEEEECHHHHCC
PTMANDGNGIDPNPDDPGDAATPGGSSWHGTHVAGTVAARADGSGVVGVAWDARVMPLRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCEEEEEEE
LGVGGGTSYDIVQAVSYAAGLANDSGTVPATRAAVVNLSLGCQGCFSSTEQAVYNAARNA
EECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCC
GVIVVAAAGNEASSAPGYPAAYAGVLSVSAVDMKGAKAPYSNTGSTVDLAAPGGNTAVDL
CEEEEEECCCCCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEE
DGNGYADGVLSTLVKDTTGTREPIYAFYQGTSMAAPHVAGVMALVKSVCPSLAPAAVDQL
CCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LQEGQLTRDLGTPGRDDTFGWGLVDALKAVQAAATSCGAPLPPSLSVTPGRLDFGPADAT
HHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCE
LQLQAAKVGEGALTVTAVSDDAAWLTVTAPGVDASGLGAYAAAVDRTGLADGRYAAKITF
EEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEE
TPSVGDPVVIPVTLQVGAAAAAGDAGYLYALLVREGVSGPELVKQWSGAASGGSYAFRFD
CCCCCCCEEEEEEEEECCCCCCCCCHHEEEEHHHCCCCCHHHHHHHCCCCCCCCEEEEEC
GVSAGTYYLVAGSDMNNDGYICDAGESCGAWPTLGVLTPLGASGPRSDLDFSVAFDPAVA
CCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCC
PVGAAAGAPVGARGLARQPATKGVAGLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]