Click here to switch to the map view.

The map label for this gene is bah [H]

Identifier: 220915042

GI number: 220915042

Start: 417288

End: 418190

Strand: Reverse

Name: bah [H]

Synonym: Mnod_8210

Alternate gene names: 220915042

Gene position: 418190-417288 (Counterclockwise)

Preceding gene: 220915043

Following gene: 220915041

Centisome position: 91.29

GC content: 65.12

Gene sequence:

>903_bases
ATGACGGTTTCCGAAATCGATGCCATTCGGCACCTTCTGCTCGCGCAGCCGCGGCCGACGGACCCCGCCGCACGACGGGA
GCGGATGAACAGCTTCGGCCGACGCTACGCGCTCCCCGCGGACGTGAGCGTCACCGCTGCCGACGCAGGAGGCGTCCCAG
CTGAGTGGACCGTCACTCCGGGTGCGGACCCTAATCGCGTCCTCATCTTCCTCCACGGCGGGGGCTACATGGCAGGCTCC
CTCGACAGTCATCGCCACGTGGTCGCGCAGGCCGGACGTGAGGCCCAGGCGCGCACGCTCGCGCTCGATTATCGTCTCAC
ACCCGAGCACCCGTTTCCCGCTGCCCTCGACGACGCTCTCGCGGGCTACCGCTTCGTCATAGAGCGCGGGGTTGCGCCCC
GTCGCATCGTTCTATCCGGCGAGAGCGCAGGCGGGGGTCTTGCCCTCGCGACGTTGCTCCGTCTGCGCGAAGCTGGGGAG
CCCTTGCCAGGGTGCGTGTGGCTCAGCTCACCCTGGGTTGACCTTACCTTGAGCGGTGACAGCCTGATCACCAAAGCGGC
AGTCGATCCACTGATCCAGAAGCCCTACCTTGCTGAACTGGCGCGCGCCTACCTGAACAGCGCTGATCCGCACGATCCCC
TGATCTCGCCTCTTTACGCTGACCTACGCGGCCTTCCCCCTATGCTGATCCAGGTCGGCTCTTCTGAAACACTCCTCGAT
GACGCTGTGCGCCTCGCAGGAGCGGCTGGAGGCGCGGACGTTAGCGTCACGCTCCGGATCTGGCCTGAGATGATCCACGC
CTGGCACCTCTTCTACCCACAGCTTGCAGCAGGTCGAGCAGCCCTGGCTGAGGTAGGCAGGTTTGTGGATACTTGCATCA
ATTATGCCGGCGAGCGAAGATAA

Upstream 100 bases:

>100_bases
CGACCGGACCAGTATGTCGCGCATGTCCTGCCGCTCGATGCTCATACCGAGCTGCCGGCTTTCTTCGACAGGTTCATGAC
GTGAGCGACGAGGCAGTGCG

Downstream 100 bases:

>100_bases
TAATCCGCCTCGAACTGCACCTTGGCACAGACTGGGGCCCGCGTGGGGCTCCAGCCATTGGTCGCTTGTTTTCGGAAACC
GTGTCAGGAAATCAAAAGTC

Product: Alpha/beta hydrolase fold-3 domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTVSEIDAIRHLLLAQPRPTDPAARRERMNSFGRRYALPADVSVTAADAGGVPAEWTVTPGADPNRVLIFLHGGGYMAGS
LDSHRHVVAQAGREAQARTLALDYRLTPEHPFPAALDDALAGYRFVIERGVAPRRIVLSGESAGGGLALATLLRLREAGE
PLPGCVWLSSPWVDLTLSGDSLITKAAVDPLIQKPYLAELARAYLNSADPHDPLISPLYADLRGLPPMLIQVGSSETLLD
DAVRLAGAAGGADVSVTLRIWPEMIHAWHLFYPQLAAGRAALAEVGRFVDTCINYAGERR

Sequences:

>Translated_300_residues
MTVSEIDAIRHLLLAQPRPTDPAARRERMNSFGRRYALPADVSVTAADAGGVPAEWTVTPGADPNRVLIFLHGGGYMAGS
LDSHRHVVAQAGREAQARTLALDYRLTPEHPFPAALDDALAGYRFVIERGVAPRRIVLSGESAGGGLALATLLRLREAGE
PLPGCVWLSSPWVDLTLSGDSLITKAAVDPLIQKPYLAELARAYLNSADPHDPLISPLYADLRGLPPMLIQVGSSETLLD
DAVRLAGAAGGADVSVTLRIWPEMIHAWHLFYPQLAAGRAALAEVGRFVDTCINYAGERR
>Mature_299_residues
TVSEIDAIRHLLLAQPRPTDPAARRERMNSFGRRYALPADVSVTAADAGGVPAEWTVTPGADPNRVLIFLHGGGYMAGSL
DSHRHVVAQAGREAQARTLALDYRLTPEHPFPAALDDALAGYRFVIERGVAPRRIVLSGESAGGGLALATLLRLREAGEP
LPGCVWLSSPWVDLTLSGDSLITKAAVDPLIQKPYLAELARAYLNSADPHDPLISPLYADLRGLPPMLIQVGSSETLLDD
AVRLAGAAGGADVSVTLRIWPEMIHAWHLFYPQLAAGRAALAEVGRFVDTCINYAGERR

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=142, Percent_Identity=30.2816901408451, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1786682, Length=241, Percent_Identity=28.6307053941909, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17567059, Length=265, Percent_Identity=27.1698113207547, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115533410, Length=149, Percent_Identity=30.2013422818792, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533412, Length=149, Percent_Identity=30.2013422818792, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.-

Molecular weight: Translated: 32174; Mature: 32043

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSEIDAIRHLLLAQPRPTDPAARRERMNSFGRRYALPADVSVTAADAGGVPAEWTVTP
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEECCCCCCCCEEEECC
GADPNRVLIFLHGGGYMAGSLDSHRHVVAQAGREAQARTLALDYRLTPEHPFPAALDDAL
CCCCCEEEEEEECCCEEECCCCCHHHHHHHCCCCHHCEEEEEEEEECCCCCCCHHHHHHH
AGYRFVIERGVAPRRIVLSGESAGGGLALATLLRLREAGEPLPGCVWLSSPWVDLTLSGD
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCC
SLITKAAVDPLIQKPYLAELARAYLNSADPHDPLISPLYADLRGLPPMLIQVGSSETLLD
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHEEEECCCCHHHH
DAVRLAGAAGGADVSVTLRIWPEMIHAWHLFYPQLAAGRAALAEVGRFVDTCINYAGERR
HHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVSEIDAIRHLLLAQPRPTDPAARRERMNSFGRRYALPADVSVTAADAGGVPAEWTVTP
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEECCCCCCCCEEEECC
GADPNRVLIFLHGGGYMAGSLDSHRHVVAQAGREAQARTLALDYRLTPEHPFPAALDDAL
CCCCCEEEEEEECCCEEECCCCCHHHHHHHCCCCHHCEEEEEEEEECCCCCCCHHHHHHH
AGYRFVIERGVAPRRIVLSGESAGGGLALATLLRLREAGEPLPGCVWLSSPWVDLTLSGD
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCC
SLITKAAVDPLIQKPYLAELARAYLNSADPHDPLISPLYADLRGLPPMLIQVGSSETLLD
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHEEEECCCCHHHH
DAVRLAGAAGGADVSVTLRIWPEMIHAWHLFYPQLAAGRAALAEVGRFVDTCINYAGERR
HHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]