Click here to switch to the map view.

The map label for this gene is yfdZ [H]

Identifier: 220905574

GI number: 220905574

Start: 2781319

End: 2782500

Strand: Direct

Name: yfdZ [H]

Synonym: Ddes_2313

Alternate gene names: 220905574

Gene position: 2781319-2782500 (Clockwise)

Preceding gene: 220905568

Following gene: 220905575

Centisome position: 96.79

GC content: 59.48

Gene sequence:

>1182_bases
ATGGAAGAGTTTTCACGCATTCGCCGTCTGCCCCCCTACGTTTTCGCCGTGGTGGGGGACCTCAAGATGCAACTTCGTCG
GCAGAATATCGACATCGTGGACTTCAGCATGGGCAACCCGGACATTCCCACGCCCGCCCCCATTGTGGAAAAGCTCACCG
AGGCCGCAGCCAAGCCCATCAACCACCGCTACTCCCTTTCCCGTGGCATCCCCAACCTGCGCAAGGCCGTCTGTGACCGC
TACAAGCGCCACTTCGGCGTGGAGCTTGACCCGGACAGCGAAGCCATTGTGACAATGGGTTCCAAGGAAGGACTGGCCCA
CCTTTCGCTGGCCATGCTTGAACCGGGCGATGTGGTGCTTGCACCGGACCCCACCTACCCCATTCACAAATACGCGCCCG
TCATCGCAGGCGCGGATGTGCGCAGCGTGCCCATTGGTTCCGGCCGCGACTTTTTTGAAGACCTTGAGGCCGCCATGCGG
CATGCCTGGCCCAAGCCCAAGCTGCTTTTCCTCTGCTACCCGCACAATCCCACCACCGAGGTGACGGACCTGGCTTTTTT
TGAAAGGATTGTCGACTTCGCCAAGGCCAACAACATCTGGGTCATCCACGATCTGGCCTACGCGGACCTGGTGTTTGACG
GCTACAAAGCCCCGAGCTTCCTGCAGGCCAAGGGGGCCAAGGACGTGGGCGTGGAGTTTTACACCCTGTCCAAAAGCTAT
TCCATGCCAGGCTGGCGCGTGGGCTTCTGCCTGGGCAACAAGCAGCTTATTCACGCTCTTGGCCGCATCAAGAGCTATCT
TGACTACGGCATCTTCCAGCCCGTGCAGATCGCTGCTACCGTGGCGCTCAACGGTTCCGAAGACTGTGTGAACAATATCT
GCAACATTTATAAGGAGCGGCGCGACCGCCTCGTTGACGGCCTGAACCGCATAGGTTGGGAGGTTCCCTCGCCCAAGGCC
ACCATGTTCGTATGGGCGCGCATACCCGAAGCCTTCCGCAAGATGGGTTCGGTGGAGTTTTCCAAGCTGCTGCTTACAGA
GGCCCATGTGGCGGTTTCTCCGGGGCTGGGCTTCGGCTCTTACGGAGACGAGTTTGTCCGTTTTGCCCTTATCGAAAACG
AACACCGCACACGGCAGGCCATCAGCAGCATGCGCAAACTGCTGTCGGGCACGTCCGACTAG

Upstream 100 bases:

>100_bases
TTTTTCAGTACGCGCGGCCAGGCAGCACAGCAGGCCGCCGCGCCAACGCAAGGGCGCTTTTGCCTTTGACGAGACAATCA
TCATGCTCCGGAGCAGGACA

Downstream 100 bases:

>100_bases
CGCAGATCAACCTTGAAAAAGTTTACATGGGCTAACGCTGCACGGGCGTGCAGCGCGCCGTAATACGGCGAACGCCTGCT
CGTGCAGCCCTTGGGGCTGC

Product: class I and II aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MEEFSRIRRLPPYVFAVVGDLKMQLRRQNIDIVDFSMGNPDIPTPAPIVEKLTEAAAKPINHRYSLSRGIPNLRKAVCDR
YKRHFGVELDPDSEAIVTMGSKEGLAHLSLAMLEPGDVVLAPDPTYPIHKYAPVIAGADVRSVPIGSGRDFFEDLEAAMR
HAWPKPKLLFLCYPHNPTTEVTDLAFFERIVDFAKANNIWVIHDLAYADLVFDGYKAPSFLQAKGAKDVGVEFYTLSKSY
SMPGWRVGFCLGNKQLIHALGRIKSYLDYGIFQPVQIAATVALNGSEDCVNNICNIYKERRDRLVDGLNRIGWEVPSPKA
TMFVWARIPEAFRKMGSVEFSKLLLTEAHVAVSPGLGFGSYGDEFVRFALIENEHRTRQAISSMRKLLSGTSD

Sequences:

>Translated_393_residues
MEEFSRIRRLPPYVFAVVGDLKMQLRRQNIDIVDFSMGNPDIPTPAPIVEKLTEAAAKPINHRYSLSRGIPNLRKAVCDR
YKRHFGVELDPDSEAIVTMGSKEGLAHLSLAMLEPGDVVLAPDPTYPIHKYAPVIAGADVRSVPIGSGRDFFEDLEAAMR
HAWPKPKLLFLCYPHNPTTEVTDLAFFERIVDFAKANNIWVIHDLAYADLVFDGYKAPSFLQAKGAKDVGVEFYTLSKSY
SMPGWRVGFCLGNKQLIHALGRIKSYLDYGIFQPVQIAATVALNGSEDCVNNICNIYKERRDRLVDGLNRIGWEVPSPKA
TMFVWARIPEAFRKMGSVEFSKLLLTEAHVAVSPGLGFGSYGDEFVRFALIENEHRTRQAISSMRKLLSGTSD
>Mature_393_residues
MEEFSRIRRLPPYVFAVVGDLKMQLRRQNIDIVDFSMGNPDIPTPAPIVEKLTEAAAKPINHRYSLSRGIPNLRKAVCDR
YKRHFGVELDPDSEAIVTMGSKEGLAHLSLAMLEPGDVVLAPDPTYPIHKYAPVIAGADVRSVPIGSGRDFFEDLEAAMR
HAWPKPKLLFLCYPHNPTTEVTDLAFFERIVDFAKANNIWVIHDLAYADLVFDGYKAPSFLQAKGAKDVGVEFYTLSKSY
SMPGWRVGFCLGNKQLIHALGRIKSYLDYGIFQPVQIAATVALNGSEDCVNNICNIYKERRDRLVDGLNRIGWEVPSPKA
TMFVWARIPEAFRKMGSVEFSKLLLTEAHVAVSPGLGFGSYGDEFVRFALIENEHRTRQAISSMRKLLSGTSD

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=373, Percent_Identity=25.201072386059, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI56713254, Length=373, Percent_Identity=25.201072386059, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=22.64631043257, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=22.64631043257, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=59.4805194805195, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=26.6129032258064, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788627, Length=381, Percent_Identity=22.8346456692913, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788332, Length=211, Percent_Identity=27.4881516587678, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=393, Percent_Identity=25.4452926208651, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=393, Percent_Identity=25.4452926208651, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=396, Percent_Identity=21.969696969697, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=21.3740458015267, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573069, Length=423, Percent_Identity=24.113475177305, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646114, Length=423, Percent_Identity=24.113475177305, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573067, Length=423, Percent_Identity=24.113475177305, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573065, Length=423, Percent_Identity=24.113475177305, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43981; Mature: 43981

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFSRIRRLPPYVFAVVGDLKMQLRRQNIDIVDFSMGNPDIPTPAPIVEKLTEAAAKPI
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCC
NHRYSLSRGIPNLRKAVCDRYKRHFGVELDPDSEAIVTMGSKEGLAHLSLAMLEPGDVVL
CCHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCHHHEEEEEECCCCEEE
APDPTYPIHKYAPVIAGADVRSVPIGSGRDFFEDLEAAMRHAWPKPKLLFLCYPHNPTTE
CCCCCCCCHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
VTDLAFFERIVDFAKANNIWVIHDLAYADLVFDGYKAPSFLQAKGAKDVGVEFYTLSKSY
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCC
SMPGWRVGFCLGNKQLIHALGRIKSYLDYGIFQPVQIAATVALNGSEDCVNNICNIYKER
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHH
RDRLVDGLNRIGWEVPSPKATMFVWARIPEAFRKMGSVEFSKLLLTEAHVAVSPGLGFGS
HHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCCCC
YGDEFVRFALIENEHRTRQAISSMRKLLSGTSD
CCHHHHEEHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEEFSRIRRLPPYVFAVVGDLKMQLRRQNIDIVDFSMGNPDIPTPAPIVEKLTEAAAKPI
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCC
NHRYSLSRGIPNLRKAVCDRYKRHFGVELDPDSEAIVTMGSKEGLAHLSLAMLEPGDVVL
CCHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCCHHHEEEEEECCCCEEE
APDPTYPIHKYAPVIAGADVRSVPIGSGRDFFEDLEAAMRHAWPKPKLLFLCYPHNPTTE
CCCCCCCCHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
VTDLAFFERIVDFAKANNIWVIHDLAYADLVFDGYKAPSFLQAKGAKDVGVEFYTLSKSY
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCC
SMPGWRVGFCLGNKQLIHALGRIKSYLDYGIFQPVQIAATVALNGSEDCVNNICNIYKER
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHH
RDRLVDGLNRIGWEVPSPKATMFVWARIPEAFRKMGSVEFSKLLLTEAHVAVSPGLGFGS
HHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCCCC
YGDEFVRFALIENEHRTRQAISSMRKLLSGTSD
CCHHHHEEHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]