Click here to switch to the map view.

The map label for this gene is motA [H]

Identifier: 220905441

GI number: 220905441

Start: 2630418

End: 2631266

Strand: Direct

Name: motA [H]

Synonym: Ddes_2179

Alternate gene names: 220905441

Gene position: 2630418-2631266 (Clockwise)

Preceding gene: 220905440

Following gene: 220905442

Centisome position: 91.54

GC content: 54.89

Gene sequence:

>849_bases
ATGTATTTATTAATTGGTCTGGCCATCGTCGCGGGTTCGGTGTTCACGGGCTACACCTTGGCCCACGGTGAATGGGGTAT
CCTTTTCCAGCCTGCGGAATTTATTATTATTCTGGGTTGCGGCCTGGGAGCTTTTTTTGGCTCGCAGACCAAGTATACCT
TCGGGCTTATTCTCAAAAGCCTGAAACACCTCTTTGCGGACCCCGGTTCAAGCAAAGGGCGCTACCTGGAAACACTGGCC
CTGCTCTATGCGCTTTTTTCCAAGATGCACCGCGAGGGCGTCATCAGTATTGAAAGTGATGTGGAAAAACCCGAATCCAG
TCCCATTTTCAGCAAATATCCCAATGTTTCCAAAGACACCAAGGTTGTCAACTTCATAGGCGATACCCTGCGGGTCTACC
TGACCACTGGCGACCCCGCAGACATCGACAGTCTTATGGATGTCGACATTACCACCATGCGCGAAGAAGGCATCCTGCCT
GCGCATGCCGTGTCACACATGGCCGAATCACTGCCGGGCATGGGTATTGTGGCCTGCGTTCTCGGCGTGGTGCTTGCCAT
GGGCAAGATCAACGAGCCGCCGGAAGTGCTCGGGCACTATATCGGGGCGGCCCTTGTGGGTACGTTCTTCGGTATTCTCT
GCTGCTACGGCCTGTTTGGCCCCATGGGTTCCAAGCTCGAAAACTATGTGGCCGAAGAGCATTTCTACTATCACTCTGTC
AAAGAGGCCGTGGCTGCCGCCATTCGCGGCTCCACCCCCCTTATTGCCGTGGAGTACGGACGCAGGGCCATCCCCTATCC
TTTCCGCCCCAGCTTCGCGGAAATGGAAGACAAGCTGAAGAGCGGCTAG

Upstream 100 bases:

>100_bases
GGCCTGTAACGCGGCCTGCGGCAGTTCTCCGGGCGATGGTTTGTCCCGGCACGGCAGGTAAAAAAACGACACAGGATGAA
TTGAGCCTACAGGCGGCACT

Downstream 100 bases:

>100_bases
GCAATCGGCGCGGCCTTCGGGCTGCCTGCCATATCTTGCTGAACTTTACACCGCAGGGCGCCCTGCACACTCTGTGGCGC
AGGCATTTCCGAGCGTCCGG

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MYLLIGLAIVAGSVFTGYTLAHGEWGILFQPAEFIIILGCGLGAFFGSQTKYTFGLILKSLKHLFADPGSSKGRYLETLA
LLYALFSKMHREGVISIESDVEKPESSPIFSKYPNVSKDTKVVNFIGDTLRVYLTTGDPADIDSLMDVDITTMREEGILP
AHAVSHMAESLPGMGIVACVLGVVLAMGKINEPPEVLGHYIGAALVGTFFGILCCYGLFGPMGSKLENYVAEEHFYYHSV
KEAVAAAIRGSTPLIAVEYGRRAIPYPFRPSFAEMEDKLKSG

Sequences:

>Translated_282_residues
MYLLIGLAIVAGSVFTGYTLAHGEWGILFQPAEFIIILGCGLGAFFGSQTKYTFGLILKSLKHLFADPGSSKGRYLETLA
LLYALFSKMHREGVISIESDVEKPESSPIFSKYPNVSKDTKVVNFIGDTLRVYLTTGDPADIDSLMDVDITTMREEGILP
AHAVSHMAESLPGMGIVACVLGVVLAMGKINEPPEVLGHYIGAALVGTFFGILCCYGLFGPMGSKLENYVAEEHFYYHSV
KEAVAAAIRGSTPLIAVEYGRRAIPYPFRPSFAEMEDKLKSG
>Mature_282_residues
MYLLIGLAIVAGSVFTGYTLAHGEWGILFQPAEFIIILGCGLGAFFGSQTKYTFGLILKSLKHLFADPGSSKGRYLETLA
LLYALFSKMHREGVISIESDVEKPESSPIFSKYPNVSKDTKVVNFIGDTLRVYLTTGDPADIDSLMDVDITTMREEGILP
AHAVSHMAESLPGMGIVACVLGVVLAMGKINEPPEVLGHYIGAALVGTFFGILCCYGLFGPMGSKLENYVAEEHFYYHSV
KEAVAAAIRGSTPLIAVEYGRRAIPYPFRPSFAEMEDKLKSG

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=282, Percent_Identity=38.6524822695035, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30579; Mature: 30579

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLLIGLAIVAGSVFTGYTLAHGEWGILFQPAEFIIILGCGLGAFFGSQTKYTFGLILKS
CCHHHHHHHHHHHHHHCEEEECCCCCEEECCCCEEEEEECCHHHHHCCCCHHHHHHHHHH
LKHLFADPGSSKGRYLETLALLYALFSKMHREGVISIESDVEKPESSPIFSKYPNVSKDT
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCHHHCCCCCCCH
KVVNFIGDTLRVYLTTGDPADIDSLMDVDITTMREEGILPAHAVSHMAESLPGMGIVACV
HHHHHHCCEEEEEEECCCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
LGVVLAMGKINEPPEVLGHYIGAALVGTFFGILCCYGLFGPMGSKLENYVAEEHFYYHSV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KEAVAAAIRGSTPLIAVEYGRRAIPYPFRPSFAEMEDKLKSG
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MYLLIGLAIVAGSVFTGYTLAHGEWGILFQPAEFIIILGCGLGAFFGSQTKYTFGLILKS
CCHHHHHHHHHHHHHHCEEEECCCCCEEECCCCEEEEEECCHHHHHCCCCHHHHHHHHHH
LKHLFADPGSSKGRYLETLALLYALFSKMHREGVISIESDVEKPESSPIFSKYPNVSKDT
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCHHHCCCCCCCH
KVVNFIGDTLRVYLTTGDPADIDSLMDVDITTMREEGILPAHAVSHMAESLPGMGIVACV
HHHHHHCCEEEEEEECCCCCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
LGVVLAMGKINEPPEVLGHYIGAALVGTFFGILCCYGLFGPMGSKLENYVAEEHFYYHSV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KEAVAAAIRGSTPLIAVEYGRRAIPYPFRPSFAEMEDKLKSG
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]