| Definition | Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 chromosome, complete genome. |
|---|---|
| Accession | NC_011883 |
| Length | 2,873,437 |
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The map label for this gene is braF [H]
Identifier: 220905379
GI number: 220905379
Start: 2553062
End: 2553817
Strand: Direct
Name: braF [H]
Synonym: Ddes_2117
Alternate gene names: 220905379
Gene position: 2553062-2553817 (Clockwise)
Preceding gene: 220905378
Following gene: 220905380
Centisome position: 88.85
GC content: 57.54
Gene sequence:
>756_bases ATGAAAGACGTAACACAGCGCTTCGGCGGTCTTATCGCGCTGTCATGCTTCAACATACAGATCGAGGACCACAGCCTCAC GGGGCTTATCGGTCCCAACGGCGCGGGAAAAACCACGGTATTCAACCTGGCTTCACATTTTTACCACGCTACCGAGGGCG AAATCACCTTTGACGGCCACAAGTACCGGCCCAAGCTTGCGCCCCATGAAGTGACCACGCTGGGCATGGCGCGCACCTTT CAGAACATCCGCCTGTGGCCCGGCATGACGGTGCTGGACAATATCTGCGTGTCGCAATACAGCCGCCTGGGCTACGGCCT GCTGGACGCATGGTTCAACACGGGCCGCTACGGGCGCGAAGAAAAGCGCATCAAGAAAAAGGCAGCGGAAATTCTGGAAA TTATGGAGCTGGGGCATGTGGCAGAGGAACTGCCCAAAAACCTTCCCTACGGCCTGCAACGCCGTGTGGAACTGGCCCGC GCCCTTTCCACCGATCCCAAGCTGCTCTTGCTGGACGAGCCGGCGGCAGGGCTCAACTCGTCTGATGTGGACGGCCTGAT CAAGCATATCGGCTGGATTTACGACCAGTTCAAAATCGCCATATGGATGATCGAGCACCAGATGAAGGTGGTCATGTCGC TTTGCCGGCATATTACCGTGGTGGAATTCGGCCAGACCATCGCCAGCGGCACGCCGCAGGAAATCCAGAACAATCCCGAT GTCATCAAGGCCTATCTGGGCGACGAGAACGTGTAG
Upstream 100 bases:
>100_bases GCCCCGGCTCGCGTGGAATAGGCCGTGCGGCGTTACGCTTGTGCGGCCAGGTATTCAATGACTGACAACGTACTGGGGGC GAACCTTGGCACTGCTTGAA
Downstream 100 bases:
>100_bases GGGGCATCATGCTGCTTGAAGTGGAAAATCTCTATGCGGGCTACGGCAAGATAGAAGCCTTGCACGGTATCTCCTTTCAT GTGAACGAGGGCGAAATAGT
Product: ABC transporter-like protein
Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 251; Mature: 251
Protein sequence:
>251_residues MKDVTQRFGGLIALSCFNIQIEDHSLTGLIGPNGAGKTTVFNLASHFYHATEGEITFDGHKYRPKLAPHEVTTLGMARTF QNIRLWPGMTVLDNICVSQYSRLGYGLLDAWFNTGRYGREEKRIKKKAAEILEIMELGHVAEELPKNLPYGLQRRVELAR ALSTDPKLLLLDEPAAGLNSSDVDGLIKHIGWIYDQFKIAIWMIEHQMKVVMSLCRHITVVEFGQTIASGTPQEIQNNPD VIKAYLGDENV
Sequences:
>Translated_251_residues MKDVTQRFGGLIALSCFNIQIEDHSLTGLIGPNGAGKTTVFNLASHFYHATEGEITFDGHKYRPKLAPHEVTTLGMARTF QNIRLWPGMTVLDNICVSQYSRLGYGLLDAWFNTGRYGREEKRIKKKAAEILEIMELGHVAEELPKNLPYGLQRRVELAR ALSTDPKLLLLDEPAAGLNSSDVDGLIKHIGWIYDQFKIAIWMIEHQMKVVMSLCRHITVVEFGQTIASGTPQEIQNNPD VIKAYLGDENV >Mature_251_residues MKDVTQRFGGLIALSCFNIQIEDHSLTGLIGPNGAGKTTVFNLASHFYHATEGEITFDGHKYRPKLAPHEVTTLGMARTF QNIRLWPGMTVLDNICVSQYSRLGYGLLDAWFNTGRYGREEKRIKKKAAEILEIMELGHVAEELPKNLPYGLQRRVELAR ALSTDPKLLLLDEPAAGLNSSDVDGLIKHIGWIYDQFKIAIWMIEHQMKVVMSLCRHITVVEFGQTIASGTPQEIQNNPD VIKAYLGDENV
Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]
COG id: COG0411
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI27262624, Length=227, Percent_Identity=23.3480176211454, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI27262626, Length=227, Percent_Identity=23.3480176211454, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI45446740, Length=225, Percent_Identity=23.5555555555556, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI47078218, Length=225, Percent_Identity=23.5555555555556, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI27881501, Length=228, Percent_Identity=25.4385964912281, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI30795238, Length=228, Percent_Identity=25.4385964912281, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1789864, Length=242, Percent_Identity=42.1487603305785, Blast_Score=195, Evalue=2e-51, Organism=Escherichia coli, GI87081709, Length=253, Percent_Identity=26.4822134387352, Blast_Score=104, Evalue=7e-24, Organism=Escherichia coli, GI48994943, Length=234, Percent_Identity=29.4871794871795, Blast_Score=100, Evalue=9e-23, Organism=Escherichia coli, GI1788761, Length=252, Percent_Identity=25.7936507936508, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1789593, Length=249, Percent_Identity=27.3092369477912, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786398, Length=231, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787712, Length=253, Percent_Identity=28.0632411067194, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1788450, Length=247, Percent_Identity=26.3157894736842, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1789032, Length=248, Percent_Identity=27.8225806451613, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI87081791, Length=256, Percent_Identity=25.78125, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1790525, Length=255, Percent_Identity=26.2745098039216, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI48995001, Length=246, Percent_Identity=26.0162601626016, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1790467, Length=239, Percent_Identity=24.6861924686192, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787029, Length=238, Percent_Identity=24.7899159663866, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1790190, Length=228, Percent_Identity=27.1929824561404, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI87081782, Length=239, Percent_Identity=27.1966527196653, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI87082267, Length=226, Percent_Identity=24.7787610619469, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1786319, Length=221, Percent_Identity=28.9592760180996, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788897, Length=248, Percent_Identity=23.7903225806452, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1787370, Length=250, Percent_Identity=25.6, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1788472, Length=229, Percent_Identity=24.8908296943231, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789672, Length=254, Percent_Identity=24.0157480314961, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788210, Length=248, Percent_Identity=24.5967741935484, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI1786872, Length=249, Percent_Identity=22.0883534136546, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1786345, Length=239, Percent_Identity=24.2677824267782, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1789586, Length=244, Percent_Identity=27.0491803278689, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789991, Length=253, Percent_Identity=28.0632411067194, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1786253, Length=233, Percent_Identity=27.8969957081545, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI87081834, Length=195, Percent_Identity=24.1025641025641, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1788225, Length=248, Percent_Identity=24.1935483870968, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787089, Length=206, Percent_Identity=24.7572815533981, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI87082268, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1786563, Length=217, Percent_Identity=27.1889400921659, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787759, Length=247, Percent_Identity=25.9109311740891, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1787792, Length=244, Percent_Identity=22.5409836065574, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI48994997, Length=216, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1788644, Length=249, Percent_Identity=25.3012048192771, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1789873, Length=210, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787143, Length=230, Percent_Identity=26.9565217391304, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI48994883, Length=242, Percent_Identity=25.2066115702479, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1790544, Length=238, Percent_Identity=25.2100840336134, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786803, Length=234, Percent_Identity=21.7948717948718, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1790739, Length=255, Percent_Identity=22.3529411764706, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17510237, Length=235, Percent_Identity=25.1063829787234, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71983516, Length=212, Percent_Identity=28.7735849056604, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71983510, Length=212, Percent_Identity=28.7735849056604, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71983523, Length=212, Percent_Identity=28.7735849056604, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI221512771, Length=179, Percent_Identity=26.2569832402235, Blast_Score=68, Evalue=6e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 28165; Mature: 28165
Theoretical pI: Translated: 6.79; Mature: 6.79
Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKDVTQRFGGLIALSCFNIQIEDHSLTGLIGPNGAGKTTVFNLASHFYHATEGEITFDGH CCCHHHHHCCEEEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCC KYRPKLAPHEVTTLGMARTFQNIRLWPGMTVLDNICVSQYSRLGYGLLDAWFNTGRYGRE CCCCCCCCCHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH EKRIKKKAAEILEIMELGHVAEELPKNLPYGLQRRVELARALSTDPKLLLLDEPAAGLNS HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC SDVDGLIKHIGWIYDQFKIAIWMIEHQMKVVMSLCRHITVVEFGQTIASGTPQEIQNNPD CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHH VIKAYLGDENV HEEEECCCCCC >Mature Secondary Structure MKDVTQRFGGLIALSCFNIQIEDHSLTGLIGPNGAGKTTVFNLASHFYHATEGEITFDGH CCCHHHHHCCEEEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCC KYRPKLAPHEVTTLGMARTFQNIRLWPGMTVLDNICVSQYSRLGYGLLDAWFNTGRYGRE CCCCCCCCCHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH EKRIKKKAAEILEIMELGHVAEELPKNLPYGLQRRVELARALSTDPKLLLLDEPAAGLNS HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC SDVDGLIKHIGWIYDQFKIAIWMIEHQMKVVMSLCRHITVVEFGQTIASGTPQEIQNNPD CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHH VIKAYLGDENV HEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]
Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2120183; 10984043 [H]