BacMap

Definition	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 chromosome, complete genome.
Accession	NC_011883
Length	2,873,437

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The map label for this gene is braG [H]

Identifier: 220905380

GI number: 220905380

Start: 2553826

End: 2554548

Strand: Direct

Name: braG [H]

Synonym: Ddes_2118

Alternate gene names: 220905380

Gene position: 2553826-2554548 (Clockwise)

Preceding gene: 220905379

Following gene: 220905381

Centisome position: 88.88

GC content: 58.92

Gene sequence:

>723_bases
ATGCTGCTTGAAGTGGAAAATCTCTATGCGGGCTACGGCAAGATAGAAGCCTTGCACGGTATCTCCTTTCATGTGAACGA
GGGCGAAATAGTCACCCTCATCGGGGCCAACGGGGCGGGAAAATCCACCACGCTCAAGGCGGTCATGCGTCTGCCCCCGC
CGGAATCCCCCTCGGTGTTCAGCGGCGACATCCGCTTCAAGGGAGAGTCCATACTCAAAACTGAGCCGCACAACGTGGTG
GCGCGCCTCAAAATGGACCTTGTACCCGAGGGCAGGCATATTTTCGGTAACCTCACCGTGCGTGAAAACCTCAAACTTGC
CACCTGGACCCGCAAGGACGGCGGCGTAGAAAAAGACATGGACAGGGTTTTTGATCTTTTTCCCCGTCTTAAAGAGCGCA
TACACCAGCGCAGCGACACGCTTTCCGGCGGCGAGCAGCAGATGCTGGCCGTGGGCCGGGCGCTGATGACAAGCTGCTCC
GTCATCCTGCTGGACGAGCCGTCCATGGGGCTTTCGCCCCTGCTCATGTACGACATGTTCCGCACCTTCAAAAAGCTCAA
CAGCGAAGGACTCACCGTCATTGTGGTAGAGCAGAACGCCCGCCTGGCCCTGCAGGTGGCTGACCGTGGCTATGTACTGG
ATACCGGGGGCATTGTGGCCCAGGGAACCGCTGCGGAACTGGCGGATACGCCGGAAATAAAGGCCGCCTACCTGGGCGCA
TAG

Upstream 100 bases:

>100_bases
AATTCGGCCAGACCATCGCCAGCGGCACGCCGCAGGAAATCCAGAACAATCCCGATGTCATCAAGGCCTATCTGGGCGAC
GAGAACGTGTAGGGGGCATC

Downstream 100 bases:

>100_bases
CTGTTTCGCACCAACGGTAAAGGCGCCTCCGCCTTGTTGAGGCACATCAGCGGGCGACCAAAACCGGAACTGCCGGAAAA
GCAGAAGAACCGTTACAGCG

Product: ABC transporter-like protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLLEVENLYAGYGKIEALHGISFHVNEGEIVTLIGANGAGKSTTLKAVMRLPPPESPSVFSGDIRFKGESILKTEPHNVV
ARLKMDLVPEGRHIFGNLTVRENLKLATWTRKDGGVEKDMDRVFDLFPRLKERIHQRSDTLSGGEQQMLAVGRALMTSCS
VILLDEPSMGLSPLLMYDMFRTFKKLNSEGLTVIVVEQNARLALQVADRGYVLDTGGIVAQGTAAELADTPEIKAAYLGA

Sequences:

>Translated_240_residues
MLLEVENLYAGYGKIEALHGISFHVNEGEIVTLIGANGAGKSTTLKAVMRLPPPESPSVFSGDIRFKGESILKTEPHNVV
ARLKMDLVPEGRHIFGNLTVRENLKLATWTRKDGGVEKDMDRVFDLFPRLKERIHQRSDTLSGGEQQMLAVGRALMTSCS
VILLDEPSMGLSPLLMYDMFRTFKKLNSEGLTVIVVEQNARLALQVADRGYVLDTGGIVAQGTAAELADTPEIKAAYLGA
>Mature_240_residues
MLLEVENLYAGYGKIEALHGISFHVNEGEIVTLIGANGAGKSTTLKAVMRLPPPESPSVFSGDIRFKGESILKTEPHNVV
ARLKMDLVPEGRHIFGNLTVRENLKLATWTRKDGGVEKDMDRVFDLFPRLKERIHQRSDTLSGGEQQMLAVGRALMTSCS
VILLDEPSMGLSPLLMYDMFRTFKKLNSEGLTVIVVEQNARLALQVADRGYVLDTGGIVAQGTAAELADTPEIKAAYLGA

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=224, Percent_Identity=29.4642857142857, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI31657092, Length=229, Percent_Identity=29.2576419213974, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI30795238, Length=224, Percent_Identity=29.4642857142857, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI27477115, Length=231, Percent_Identity=29.8701298701299, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI47078218, Length=223, Percent_Identity=27.3542600896861, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI45446740, Length=223, Percent_Identity=27.3542600896861, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI153792144, Length=221, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI21536376, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI9955963, Length=228, Percent_Identity=28.5087719298246, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI116734710, Length=213, Percent_Identity=28.6384976525822, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI148612844, Length=239, Percent_Identity=28.0334728033473, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI255708477, Length=239, Percent_Identity=28.0334728033473, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI150417984, Length=214, Percent_Identity=30.3738317757009, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI6005701, Length=217, Percent_Identity=28.110599078341, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI105990541, Length=214, Percent_Identity=27.1028037383178, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI27262624, Length=216, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27262626, Length=216, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI9961252, Length=235, Percent_Identity=26.8085106382979, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI9961250, Length=235, Percent_Identity=26.8085106382979, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI4505771, Length=235, Percent_Identity=26.8085106382979, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI27436953, Length=217, Percent_Identity=26.7281105990783, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082268, Length=239, Percent_Identity=44.7698744769874, Blast_Score=207, Evalue=3e-55,
Organism=Escherichia coli, GI1789593, Length=242, Percent_Identity=32.6446280991736, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788225, Length=236, Percent_Identity=33.4745762711864, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787029, Length=232, Percent_Identity=28.8793103448276, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789672, Length=238, Percent_Identity=29.8319327731092, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789864, Length=255, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787792, Length=236, Percent_Identity=27.1186440677966, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790739, Length=235, Percent_Identity=31.063829787234, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788450, Length=242, Percent_Identity=30.9917355371901, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787089, Length=245, Percent_Identity=29.7959183673469, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790467, Length=245, Percent_Identity=29.3877551020408, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787112, Length=220, Percent_Identity=32.2727272727273, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081834, Length=212, Percent_Identity=29.7169811320755, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788897, Length=217, Percent_Identity=27.6497695852535, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788506, Length=248, Percent_Identity=28.2258064516129, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788761, Length=239, Percent_Identity=26.7782426778243, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790544, Length=245, Percent_Identity=27.3469387755102, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790162, Length=239, Percent_Identity=27.1966527196653, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789873, Length=223, Percent_Identity=29.1479820627803, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786872, Length=235, Percent_Identity=28.936170212766, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87081782, Length=228, Percent_Identity=29.3859649122807, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789991, Length=232, Percent_Identity=25.8620689655172, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1786398, Length=234, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787105, Length=236, Percent_Identity=30.0847457627119, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786803, Length=243, Percent_Identity=28.3950617283951, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790525, Length=226, Percent_Identity=26.5486725663717, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788644, Length=244, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081791, Length=244, Percent_Identity=26.2295081967213, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786345, Length=217, Percent_Identity=30.4147465437788, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI48995001, Length=239, Percent_Identity=28.0334728033473, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994997, Length=244, Percent_Identity=27.8688524590164, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=250, Percent_Identity=26.4, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87081709, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082267, Length=237, Percent_Identity=27.4261603375527, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790190, Length=246, Percent_Identity=25.2032520325203, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789032, Length=219, Percent_Identity=26.9406392694064, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786319, Length=202, Percent_Identity=32.6732673267327, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788165, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787712, Length=237, Percent_Identity=27.0042194092827, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI48994943, Length=232, Percent_Identity=25.4310344827586, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789962, Length=243, Percent_Identity=24.2798353909465, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1788472, Length=227, Percent_Identity=25.5506607929515, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788210, Length=241, Percent_Identity=27.3858921161826, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786253, Length=228, Percent_Identity=27.6315789473684, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787758, Length=221, Percent_Identity=25.3393665158371, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=27.3972602739726, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788053, Length=200, Percent_Identity=27.5, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=227, Percent_Identity=29.9559471365639, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193209708, Length=229, Percent_Identity=29.2576419213974, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=214, Percent_Identity=28.5046728971963, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=214, Percent_Identity=28.5046728971963, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=214, Percent_Identity=28.5046728971963, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193208177, Length=240, Percent_Identity=24.5833333333333, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=233, Percent_Identity=26.6094420600858, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=227, Percent_Identity=22.4669603524229, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=218, Percent_Identity=30.2752293577982, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17539902, Length=212, Percent_Identity=27.3584905660377, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=231, Percent_Identity=29.8701298701299, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=230, Percent_Identity=26.5217391304348, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=246, Percent_Identity=27.2357723577236, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=171, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=223, Percent_Identity=30.0448430493274, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=223, Percent_Identity=30.0448430493274, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=221, Percent_Identity=28.0542986425339, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=223, Percent_Identity=28.6995515695067, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=239, Percent_Identity=28.4518828451883, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221512771, Length=233, Percent_Identity=27.4678111587983, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648314, Length=231, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643674, Length=228, Percent_Identity=26.7543859649123, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574744, Length=221, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357907, Length=234, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=225, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574533, Length=227, Percent_Identity=27.7533039647577, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=229, Percent_Identity=27.9475982532751, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653245, Length=229, Percent_Identity=27.9475982532751, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85816269, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580553, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85724864, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580555, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920532, Length=217, Percent_Identity=28.110599078341, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24580930, Length=217, Percent_Identity=28.110599078341, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI85726357, Length=251, Percent_Identity=25.4980079681275, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI116007184, Length=228, Percent_Identity=28.5087719298246, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221500365, Length=228, Percent_Identity=28.5087719298246, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26225; Mature: 26225

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEVENLYAGYGKIEALHGISFHVNEGEIVTLIGANGAGKSTTLKAVMRLPPPESPSVF
CEEEECCHHCCCCCEEEEECEEEEECCCCEEEEEECCCCCCHHHHHHEEECCCCCCCCEE
SGDIRFKGESILKTEPHNVVARLKMDLVPEGRHIFGNLTVRENLKLATWTRKDGGVEKDM
ECEEEECCCEEEEECCHHEEEEEEEECCCCCCEEEEEEEEECCCEEEEEECCCCCCHHHH
DRVFDLFPRLKERIHQRSDTLSGGEQQMLAVGRALMTSCSVILLDEPSMGLSPLLMYDMF
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
RTFKKLNSEGLTVIVVEQNARLALQVADRGYVLDTGGIVAQGTAAELADTPEIKAAYLGA
HHHHHHCCCCCEEEEEECCCEEEEEECCCCEEEECCCEEECCCHHHHCCCCCCCEEECCC
>Mature Secondary Structure
MLLEVENLYAGYGKIEALHGISFHVNEGEIVTLIGANGAGKSTTLKAVMRLPPPESPSVF
CEEEECCHHCCCCCEEEEECEEEEECCCCEEEEEECCCCCCHHHHHHEEECCCCCCCCEE
SGDIRFKGESILKTEPHNVVARLKMDLVPEGRHIFGNLTVRENLKLATWTRKDGGVEKDM
ECEEEECCCEEEEECCHHEEEEEEEECCCCCCEEEEEEEEECCCEEEEEECCCCCCHHHH
DRVFDLFPRLKERIHQRSDTLSGGEQQMLAVGRALMTSCSVILLDEPSMGLSPLLMYDMF
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
RTFKKLNSEGLTVIVVEQNARLALQVADRGYVLDTGGIVAQGTAAELADTPEIKAAYLGA
HHHHHHCCCCCEEEEEECCCEEEEEECCCCEEEECCCEEECCCHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]