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The map label for this gene is coaD [H]

Identifier: 220905297

GI number: 220905297

Start: 2447814

End: 2448353

Strand: Direct

Name: coaD [H]

Synonym: Ddes_2035

Alternate gene names: 220905297

Gene position: 2447814-2448353 (Clockwise)

Preceding gene: 220905296

Following gene: 220905298

Centisome position: 85.19

GC content: 60.93

Gene sequence:

>540_bases
ATGAGAGTAGCCATGTACCCCGGCACCTTCGACCCGCTGACCAATGGTCATCTCAGCCTTATCCGGCGCGGGTGCGAAGT
TTTTGACCAGATTATCGTGGCCGTGGCCGACAATACGCCCAAGCGCCCCCTGTTCAGCCACGAAGAACGTGTGAACATGG
CCCGCGAGGCCCTCAAAGACGAGCCGCGCGCCCGGGTGGAACCGTTTTCTGGTCTGACGGTGGAATACGCCGCTCAGCGC
GGGGCCTGCGCCCTGCTGCGCGGGCTGCGCGCCGCCTCTGATTTTGAATATGAATTCCAGCTGGCCCTCATGAACCGCCG
CTTGCAACGCCACATCCAGACGGTTTTTCTCATGACCGACTATCAGTGGCTGTTCATAAGCTCCACCATCGTCAAGGCCG
CTGCCAGCCACGGTGCAGACATCAAGGGCCTTGTACCCGAAAACGTGCGCCTGGCCCTTCTGGAAAAATACGAAAAAGGC
GAGGTCGCCAAGGGCACCCCATGCCTTGCTCCGCCACACGGCGGATTCCGCACCTCCTGA

Upstream 100 bases:

>100_bases
CGGAAATTGAAAAGGAGGCGCGCTTTGCCGTGCCGCAGGGCTTCACCCTGGAAACCGACAGGCTGCTGGGCCAGACCCGC
ATCTGTATCTGGATAGCATC

Downstream 100 bases:

>100_bases
AGCGATACCCCCATGCCAAGCAACAGCATCTTCGGCGGGGCGGCACAGGCCGCTCCGCCATCCGAAGCACTGCCCGTCAT
CTGTCTTGCCGGCCCCACAG

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MRVAMYPGTFDPLTNGHLSLIRRGCEVFDQIIVAVADNTPKRPLFSHEERVNMAREALKDEPRARVEPFSGLTVEYAAQR
GACALLRGLRAASDFEYEFQLALMNRRLQRHIQTVFLMTDYQWLFISSTIVKAAASHGADIKGLVPENVRLALLEKYEKG
EVAKGTPCLAPPHGGFRTS

Sequences:

>Translated_179_residues
MRVAMYPGTFDPLTNGHLSLIRRGCEVFDQIIVAVADNTPKRPLFSHEERVNMAREALKDEPRARVEPFSGLTVEYAAQR
GACALLRGLRAASDFEYEFQLALMNRRLQRHIQTVFLMTDYQWLFISSTIVKAAASHGADIKGLVPENVRLALLEKYEKG
EVAKGTPCLAPPHGGFRTS
>Mature_179_residues
MRVAMYPGTFDPLTNGHLSLIRRGCEVFDQIIVAVADNTPKRPLFSHEERVNMAREALKDEPRARVEPFSGLTVEYAAQR
GACALLRGLRAASDFEYEFQLALMNRRLQRHIQTVFLMTDYQWLFISSTIVKAAASHGADIKGLVPENVRLALLEKYEKG
EVAKGTPCLAPPHGGFRTS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=153, Percent_Identity=47.0588235294118, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 20031; Mature: 20031

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAMYPGTFDPLTNGHLSLIRRGCEVFDQIIVAVADNTPKRPLFSHEERVNMAREALKD
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
EPRARVEPFSGLTVEYAAQRGACALLRGLRAASDFEYEFQLALMNRRLQRHIQTVFLMTD
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
YQWLFISSTIVKAAASHGADIKGLVPENVRLALLEKYEKGEVAKGTPCLAPPHGGFRTS
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVAMYPGTFDPLTNGHLSLIRRGCEVFDQIIVAVADNTPKRPLFSHEERVNMAREALKD
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
EPRARVEPFSGLTVEYAAQRGACALLRGLRAASDFEYEFQLALMNRRLQRHIQTVFLMTD
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
YQWLFISSTIVKAAASHGADIKGLVPENVRLALLEKYEKGEVAKGTPCLAPPHGGFRTS
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA