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The map label for this gene is modF [H]

Identifier: 220905248

GI number: 220905248

Start: 2391728

End: 2393233

Strand: Direct

Name: modF [H]

Synonym: Ddes_1986

Alternate gene names: 220905248

Gene position: 2391728-2393233 (Clockwise)

Preceding gene: 220905247

Following gene: 220905250

Centisome position: 83.24

GC content: 64.74

Gene sequence:

>1506_bases
ATGTCAGAACCGCTTGTGACCATTGAAAACCTGAGCCTTTTTCTGCCCGGTGAAGCCAGCCGGCGCTTTGTACTGCATCA
CATAGACTGGCAGATTGAACGCGGCCGCCACTGCGCTCTGCTGGGGGCCAACGGTTCGGGCAAGTCCACCCTGCTGCGCC
TGCTGCGCGGCGAACTGTGGCCCGCCGAAGGGCATATCTGGTGGCATACGCCTGACGGGCGCGAAGAATCCCCTCTGGCC
GGGCGGTCCATGACAGCCCTGGTATCACCGGCGCAACAGGAAAACTATCAGCGCCAGGCGTGGGACCTTACCGGACTCGA
CATCCTGCTCACAGGCTTTGAAGACACCCCCCTGGTGTACAGTGACGGCGGCAGCCAGGCCCAGGCCCGCAAGGACGCCG
CCGTACACATGGCTGCCCGCCTTGAGGCCGAAGGCCTGCTCGACAGGACCATGCCCACCCTTTCCCAGGGGCAATTGCGC
CTGCTGCTTCTGGGCCGGGCGCTGCTGCGTGCGCCCTCCCTGCTGCTGCTGGACGAGTGCGCCGATGGCCTGGACGCCCG
CCACCGCCAGATTTTTTTTGACGTACTCGAAGAATGCGCGCTGCGCAGCACCATCGTCATGACGGCCCACCGTCCCGGCC
AGATTCCCGACTGGTGTGCGGAACGGCGCTACATACGCCGGGGGCGCCTGCATACAGCGCCGCCGGGGCAGCCGGAGGCC
GCTACGGCCAACGGAGTGGAAAACCCCGTCGTCGCGGCGACAGGGCAGAAGCTTCAGGGACCAGCGGGCAAGGACGGACC
GGTCCCCCCCCTGCTGGACCTGGAAAATGTCACGGTGTTCATCGACAGGCAGGAAGTGCTGCGCCATATCGACTGGAGCA
TGCATCAGGGCGAACACTGGCGTATCAGCGGAGCCAACGGCTCGGGCAAGTCCACCCTGCTGCGCCTGCTGGCCGGAGAC
GAATTCGCCGCTGCCGATGGCAGGCTGGAACGCTGGCTGCCCCGGCAGGGCGGGGCAGTACACACCCTTGCCGAAGTACG
CAAGGGCATACGGCTTGTTTCCGACCTTTCCCAGGCGCTGTACGGCTATTCCCTCACGGCCCATGATATGGTCTGCACGG
GCTTTGACAACAGCATAGGCGTGTACCGCAAGTTCAGCGCTGCGGAAAAAGCCGAGGCCCTGCGCCGCATGGAAGAAATG
TTTCCCGAAGAAAGCCCGCAAGGTGTGGCGGATATCGGCCAGCTGTCCATCCGCCGCCTGTCCACAGGGCAGTTGCGCCG
CCTCTTTCTGGCGCGCGCCTTGGTGGGCGAGCCGGACATCCTGCTGCTGGACGAACCGTGCTCGGGGCTGGACGCCGCAA
GCCGCGCCCGCTATCTCGGCCTGCTTGACCTGCTGGCGGCCCGTGGCCTGCACATAGTTTTTGTTTCCCATCACGGCGAG
GATGCCCCCCTGTGCATCAACCGCGAGGCACATATGGAAGACGGACAGTTGCGCGTTGTCATGTAA

Upstream 100 bases:

>100_bases
AACGTCTGCCGGATCACGGACGCGCAGCCTTGCCGCATCAGGGTATGCAGGCCGCGGCGCGCCCGGCATATGCAGAATAA
AGACGGCAGCAGGAATATCT

Downstream 100 bases:

>100_bases
AACCGCAGCCGGTTCCAGAAACAGAAAATCCCGCTTATGGCGGGATTTTCTGTATAAACGGCACGTAAAAAACTCTCGAA
ATGCCTATTCCCCGCCGCCT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSEPLVTIENLSLFLPGEASRRFVLHHIDWQIERGRHCALLGANGSGKSTLLRLLRGELWPAEGHIWWHTPDGREESPLA
GRSMTALVSPAQQENYQRQAWDLTGLDILLTGFEDTPLVYSDGGSQAQARKDAAVHMAARLEAEGLLDRTMPTLSQGQLR
LLLLGRALLRAPSLLLLDECADGLDARHRQIFFDVLEECALRSTIVMTAHRPGQIPDWCAERRYIRRGRLHTAPPGQPEA
ATANGVENPVVAATGQKLQGPAGKDGPVPPLLDLENVTVFIDRQEVLRHIDWSMHQGEHWRISGANGSGKSTLLRLLAGD
EFAAADGRLERWLPRQGGAVHTLAEVRKGIRLVSDLSQALYGYSLTAHDMVCTGFDNSIGVYRKFSAAEKAEALRRMEEM
FPEESPQGVADIGQLSIRRLSTGQLRRLFLARALVGEPDILLLDEPCSGLDAASRARYLGLLDLLAARGLHIVFVSHHGE
DAPLCINREAHMEDGQLRVVM

Sequences:

>Translated_501_residues
MSEPLVTIENLSLFLPGEASRRFVLHHIDWQIERGRHCALLGANGSGKSTLLRLLRGELWPAEGHIWWHTPDGREESPLA
GRSMTALVSPAQQENYQRQAWDLTGLDILLTGFEDTPLVYSDGGSQAQARKDAAVHMAARLEAEGLLDRTMPTLSQGQLR
LLLLGRALLRAPSLLLLDECADGLDARHRQIFFDVLEECALRSTIVMTAHRPGQIPDWCAERRYIRRGRLHTAPPGQPEA
ATANGVENPVVAATGQKLQGPAGKDGPVPPLLDLENVTVFIDRQEVLRHIDWSMHQGEHWRISGANGSGKSTLLRLLAGD
EFAAADGRLERWLPRQGGAVHTLAEVRKGIRLVSDLSQALYGYSLTAHDMVCTGFDNSIGVYRKFSAAEKAEALRRMEEM
FPEESPQGVADIGQLSIRRLSTGQLRRLFLARALVGEPDILLLDEPCSGLDAASRARYLGLLDLLAARGLHIVFVSHHGE
DAPLCINREAHMEDGQLRVVM
>Mature_500_residues
SEPLVTIENLSLFLPGEASRRFVLHHIDWQIERGRHCALLGANGSGKSTLLRLLRGELWPAEGHIWWHTPDGREESPLAG
RSMTALVSPAQQENYQRQAWDLTGLDILLTGFEDTPLVYSDGGSQAQARKDAAVHMAARLEAEGLLDRTMPTLSQGQLRL
LLLGRALLRAPSLLLLDECADGLDARHRQIFFDVLEECALRSTIVMTAHRPGQIPDWCAERRYIRRGRLHTAPPGQPEAA
TANGVENPVVAATGQKLQGPAGKDGPVPPLLDLENVTVFIDRQEVLRHIDWSMHQGEHWRISGANGSGKSTLLRLLAGDE
FAAADGRLERWLPRQGGAVHTLAEVRKGIRLVSDLSQALYGYSLTAHDMVCTGFDNSIGVYRKFSAAEKAEALRRMEEMF
PEESPQGVADIGQLSIRRLSTGQLRRLFLARALVGEPDILLLDEPCSGLDAASRARYLGLLDLLAARGLHIVFVSHHGED
APLCINREAHMEDGQLRVVM

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=215, Percent_Identity=28.8372093023256, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI31657092, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI27262624, Length=221, Percent_Identity=27.1493212669683, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI27262626, Length=221, Percent_Identity=27.1493212669683, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI27477115, Length=223, Percent_Identity=25.1121076233184, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786975, Length=484, Percent_Identity=30.9917355371901, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1788506, Length=524, Percent_Identity=26.3358778625954, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081791, Length=232, Percent_Identity=32.3275862068966, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790190, Length=476, Percent_Identity=24.7899159663866, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790525, Length=498, Percent_Identity=22.4899598393574, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787370, Length=236, Percent_Identity=32.2033898305085, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994943, Length=500, Percent_Identity=25.4, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788897, Length=481, Percent_Identity=24.948024948025, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787029, Length=208, Percent_Identity=30.2884615384615, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787712, Length=235, Percent_Identity=28.936170212766, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790467, Length=233, Percent_Identity=30.0429184549356, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786319, Length=220, Percent_Identity=27.7272727272727, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081782, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787089, Length=234, Percent_Identity=29.4871794871795, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788761, Length=227, Percent_Identity=29.9559471365639, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=185, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081834, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790162, Length=235, Percent_Identity=25.9574468085106, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787792, Length=228, Percent_Identity=28.5087719298246, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=32.5688073394495, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790739, Length=236, Percent_Identity=27.5423728813559, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1787164, Length=230, Percent_Identity=30, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320266, Length=387, Percent_Identity=23.7726098191214, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI85724864, Length=258, Percent_Identity=28.6821705426357, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24580555, Length=258, Percent_Identity=28.6821705426357, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI85816269, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24580553, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 55247; Mature: 55116

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLVTIENLSLFLPGEASRRFVLHHIDWQIERGRHCALLGANGSGKSTLLRLLRGELW
CCCCCEEEECEEEEECCCCCCEEEEEEECEEECCCCEEEEEECCCCCHHHHHHHHHHCCC
PAEGHIWWHTPDGREESPLAGRSMTALVSPAQQENYQRQAWDLTGLDILLTGFEDTPLVY
CCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHCHHHHHCCCCCCEEEEECCCCCCEEE
SDGGSQAQARKDAAVHMAARLEAEGLLDRTMPTLSQGQLRLLLLGRALLRAPSLLLLDEC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEHHHH
ADGLDARHRQIFFDVLEECALRSTIVMTAHRPGQIPDWCAERRYIRRGRLHTAPPGQPEA
HCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
ATANGVENPVVAATGQKLQGPAGKDGPVPPLLDLENVTVFIDRQEVLRHIDWSMHQGEHW
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHHHHHHCCCCCCCCEE
RISGANGSGKSTLLRLLAGDEFAAADGRLERWLPRQGGAVHTLAEVRKGIRLVSDLSQAL
EEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YGYSLTAHDMVCTGFDNSIGVYRKFSAAEKAEALRRMEEMFPEESPQGVADIGQLSIRRL
HCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
STGQLRRLFLARALVGEPDILLLDEPCSGLDAASRARYLGLLDLLAARGLHIVFVSHHGE
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCC
DAPLCINREAHMEDGQLRVVM
CCCEEECCCCCCCCCCEEEEC
>Mature Secondary Structure 
SEPLVTIENLSLFLPGEASRRFVLHHIDWQIERGRHCALLGANGSGKSTLLRLLRGELW
CCCCEEEECEEEEECCCCCCEEEEEEECEEECCCCEEEEEECCCCCHHHHHHHHHHCCC
PAEGHIWWHTPDGREESPLAGRSMTALVSPAQQENYQRQAWDLTGLDILLTGFEDTPLVY
CCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHCHHHHHCCCCCCEEEEECCCCCCEEE
SDGGSQAQARKDAAVHMAARLEAEGLLDRTMPTLSQGQLRLLLLGRALLRAPSLLLLDEC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCEEHHHH
ADGLDARHRQIFFDVLEECALRSTIVMTAHRPGQIPDWCAERRYIRRGRLHTAPPGQPEA
HCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
ATANGVENPVVAATGQKLQGPAGKDGPVPPLLDLENVTVFIDRQEVLRHIDWSMHQGEHW
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHHHHHHCCCCCCCCEE
RISGANGSGKSTLLRLLAGDEFAAADGRLERWLPRQGGAVHTLAEVRKGIRLVSDLSQAL
EEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YGYSLTAHDMVCTGFDNSIGVYRKFSAAEKAEALRRMEEMFPEESPQGVADIGQLSIRRL
HCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
STGQLRRLFLARALVGEPDILLLDEPCSGLDAASRARYLGLLDLLAARGLHIVFVSHHGE
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCC
DAPLCINREAHMEDGQLRVVM
CCCEEECCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]