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The map label for this gene is hisK [H]

Identifier: 220905247

GI number: 220905247

Start: 2390802

End: 2391629

Strand: Direct

Name: hisK [H]

Synonym: Ddes_1985

Alternate gene names: 220905247

Gene position: 2390802-2391629 (Clockwise)

Preceding gene: 220905246

Following gene: 220905248

Centisome position: 83.2

GC content: 60.02

Gene sequence:

>828_bases
ATGATCCTTGCAGACCTGCACACCCATACCAAATACTCGCACGGCGGCAACAGCCCGGCTGAAATGCACGCGGCTGCACA
GGCCAGGGGCATTGAACTTATCGGCTTTACCGAACATTCTCCCCGGCCGGTGGGCTTTGACTACACGCACGAATACCGCG
ACAGGCTCACCCGCCACCTGCCGGACTACGCCAGCGAGGTGCTGGCCCTCAAGGCGGCCAATGCGGACGGCCCCTGCCGG
GTGCTTTTCGGCATGGAGATGGACTGGCTGGAAGGGCAGACAGACTTTACCCGCGCCTCCAGCACAGCCTACGATTTTGA
TTACCTGCTCGGCAGCGTGCATTTTATCGGGCGCTGGGGTTTTGACGACGGCGCCGACCCGTGGAGGGCCATGTCGCAGG
AAGAGTGCGAAGTACAGTATACGCACTATTTTGAAGCCTGGGAGGCCATGCTGGCCTCGGGGCTGTTCAATATCGCGGCG
CACCCGGACCTTATCAAGATTTTTTCCGTAGAGCAGTTTCACATCTGGCTGCACAAGCCGCAAAGCCGGGAACTTGTACG
CCGGGGGCTGACCGCCCTGCGCAAGTCTGGAATGAGTATGGAAATCTCATCCGCCGGTATACGCAAGGCATGCCGCGAAA
TCTATCCCGCGCCACCCATCATGGTCATGGCTGCGGAAATGGAGCTGCCCATAAGCTTCGCCTCGGACGCTCACGTTACC
GATGACGTAGGCTACGGCTTCGCCCGTCTTGCCTCTTACGCCAGCGCCTTCGGTTTCAGGGAGTACACGGTTTTCGACCG
TGGGCGGCGCAGCGTCCACCCCTTTTAA

Upstream 100 bases:

>100_bases
CATCTTGCCAGCCGGGACTTTCAGGGTCATACTGGTCATAATAACAACCATCCCCGCCAATGGGGCCGGAACCATCCCGG
AGCATTCAGGAATACCCGTC

Downstream 100 bases:

>100_bases
CGTCTGCCGGATCACGGACGCGCAGCCTTGCCGCATCAGGGTATGCAGGCCGCGGCGCGCCCGGCATATGCAGAATAAAG
ACGGCAGCAGGAATATCTAT

Product: histidinol phosphate phosphatase protein

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MILADLHTHTKYSHGGNSPAEMHAAAQARGIELIGFTEHSPRPVGFDYTHEYRDRLTRHLPDYASEVLALKAANADGPCR
VLFGMEMDWLEGQTDFTRASSTAYDFDYLLGSVHFIGRWGFDDGADPWRAMSQEECEVQYTHYFEAWEAMLASGLFNIAA
HPDLIKIFSVEQFHIWLHKPQSRELVRRGLTALRKSGMSMEISSAGIRKACREIYPAPPIMVMAAEMELPISFASDAHVT
DDVGYGFARLASYASAFGFREYTVFDRGRRSVHPF

Sequences:

>Translated_275_residues
MILADLHTHTKYSHGGNSPAEMHAAAQARGIELIGFTEHSPRPVGFDYTHEYRDRLTRHLPDYASEVLALKAANADGPCR
VLFGMEMDWLEGQTDFTRASSTAYDFDYLLGSVHFIGRWGFDDGADPWRAMSQEECEVQYTHYFEAWEAMLASGLFNIAA
HPDLIKIFSVEQFHIWLHKPQSRELVRRGLTALRKSGMSMEISSAGIRKACREIYPAPPIMVMAAEMELPISFASDAHVT
DDVGYGFARLASYASAFGFREYTVFDRGRRSVHPF
>Mature_275_residues
MILADLHTHTKYSHGGNSPAEMHAAAQARGIELIGFTEHSPRPVGFDYTHEYRDRLTRHLPDYASEVLALKAANADGPCR
VLFGMEMDWLEGQTDFTRASSTAYDFDYLLGSVHFIGRWGFDDGADPWRAMSQEECEVQYTHYFEAWEAMLASGLFNIAA
HPDLIKIFSVEQFHIWLHKPQSRELVRRGLTALRKSGMSMEISSAGIRKACREIYPAPPIMVMAAEMELPISFASDAHVT
DDVGYGFARLASYASAFGFREYTVFDRGRRSVHPF

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 31052; Mature: 31052

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILADLHTHTKYSHGGNSPAEMHAAAQARGIELIGFTEHSPRPVGFDYTHEYRDRLTRHL
CEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHC
PDYASEVLALKAANADGPCRVLFGMEMDWLEGQTDFTRASSTAYDFDYLLGSVHFIGRWG
HHHHHHHHEEEECCCCCCEEEEECCCHHHHCCCCCHHHCCCCHHHHHHHHHHHHEEEEEC
FDDGADPWRAMSQEECEVQYTHYFEAWEAMLASGLFNIAAHPDLIKIFSVEQFHIWLHKP
CCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEECC
QSRELVRRGLTALRKSGMSMEISSAGIRKACREIYPAPPIMVMAAEMELPISFASDAHVT
CHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCC
DDVGYGFARLASYASAFGFREYTVFDRGRRSVHPF
CCCCHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCC
>Mature Secondary Structure
MILADLHTHTKYSHGGNSPAEMHAAAQARGIELIGFTEHSPRPVGFDYTHEYRDRLTRHL
CEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHC
PDYASEVLALKAANADGPCRVLFGMEMDWLEGQTDFTRASSTAYDFDYLLGSVHFIGRWG
HHHHHHHHEEEECCCCCCEEEEECCCHHHHCCCCCHHHCCCCHHHHHHHHHHHHEEEEEC
FDDGADPWRAMSQEECEVQYTHYFEAWEAMLASGLFNIAAHPDLIKIFSVEQFHIWLHKP
CCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEECC
QSRELVRRGLTALRKSGMSMEISSAGIRKACREIYPAPPIMVMAAEMELPISFASDAHVT
CHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCC
DDVGYGFARLASYASAFGFREYTVFDRGRRSVHPF
CCCCHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]