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The map label for this gene is corC [H]

Identifier: 220905198

GI number: 220905198

Start: 2331840

End: 2332955

Strand: Direct

Name: corC [H]

Synonym: Ddes_1936

Alternate gene names: 220905198

Gene position: 2331840-2332955 (Clockwise)

Preceding gene: 220905197

Following gene: 220905199

Centisome position: 81.15

GC content: 62.37

Gene sequence:

>1116_bases
TTGGACGGTGGTTCGGAAGGTCATAGTACCATCTGGTCGCGCCTGAGCAGGCTGTTCGGGCACGATGATCAGGAATCTCT
GGAAAAAGCCATTCTTGAAGCGCGCGCCGAAGGCGAGGTGGAACCCGATGAGGAATCCATGCTGCTCGGCATCTTGCGGT
TCAACGACCTCCAGGTGCAGGACACCATGATTCCGCGCACCGATATCGACTGCGTGCCTCATGACATGCCCATGGCGGAG
GTGGCGGCCATCATTGTCCGCTCCGGGCACTCCCGCATTCCCGTCTACAAGGAAACCCGCGACAATATCGTGGGCATCCT
GCATGCCAAGGACCTGCTGCGCAGCATGCTTGACGGCGAGGGCAAAGTGTCATCACTGGCTGGCCTCATCCGCGAGCCGT
TCTTTGTACCCGAAACAAAATCCATCCGTACTCTGCTTCAGGAATTCCGCGCGCGCAAGCAGCACATTGCCATTGCTCTG
GACGAGTACGGCGGAACCTCGGGTCTCATCACCATTGAGGACGTGCTGGAAGAAATCGTGGGCGACATTGAAGACGAACA
CGATACCCCGCGTGAAGAAGACATACGCCCCGTGGGCGACAATATTTACGAGCTCACCGGCCGCGCGCTGCTTGAAGACC
TTGAAGATATGGGCGTGGACCTCGATTCGGACGAGGTAGACACCATCGGCGGCTACCTCAGCATGGAGGCAGGGCATGTA
CCCGCCCCCGGCGAAAGCTTCACCTTGCGCGGCTGGACGTTTACCGTGCTTGAGGCCGACCGGAAACTGATTCTGCGTCT
GCGGATGGAACCGGCCGACAGCGCTGCCAGCCGGCAGACTGCCGGACAGGATACCGCACAGCAGGATGGAGAACAGGGCG
CCGGGCCAGAGGCGGCACAGGACGCCGCGCAGGATGAGGCATCTGACGATCCTGCCGTGGCCCCGCGCTACGAAACACTG
CCGGGCAGCCTTGGCGCTGCCGCCCCCCTGGACGATGCAGCGGCATCTCCCCAGGCCGCAGTGCAAGCCGCCGAGGAAAT
CCTCCGCAGCACGCCGCCCCCGGCGGCCGAAACAGGAGATGACGCGCCCCGCCCTACGGAGTCCCCACGGGTATGA

Upstream 100 bases:

>100_bases
AACCGCCAGAAGCATCCGCAGGCGCGGCATGCCGCGCGGCGAACATGGCCCACGGGGCGCATAGTGCGGCCCGGTCCCAT
TCCCAACCAAGGAGACTACA

Downstream 100 bases:

>100_bases
CCTTTTTTCCGTCGGCTGCATCTCGGCCCGAGGGACGCATCTTGCCCGTGGCCCTTGCGGGGGCCTTGGGACTGTGGCTC
GGTTTTCCCAATGACCTTGC

Product: CBS domain containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MDGGSEGHSTIWSRLSRLFGHDDQESLEKAILEARAEGEVEPDEESMLLGILRFNDLQVQDTMIPRTDIDCVPHDMPMAE
VAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDGEGKVSSLAGLIREPFFVPETKSIRTLLQEFRARKQHIAIAL
DEYGGTSGLITIEDVLEEIVGDIEDEHDTPREEDIRPVGDNIYELTGRALLEDLEDMGVDLDSDEVDTIGGYLSMEAGHV
PAPGESFTLRGWTFTVLEADRKLILRLRMEPADSAASRQTAGQDTAQQDGEQGAGPEAAQDAAQDEASDDPAVAPRYETL
PGSLGAAAPLDDAAASPQAAVQAAEEILRSTPPPAAETGDDAPRPTESPRV

Sequences:

>Translated_371_residues
MDGGSEGHSTIWSRLSRLFGHDDQESLEKAILEARAEGEVEPDEESMLLGILRFNDLQVQDTMIPRTDIDCVPHDMPMAE
VAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDGEGKVSSLAGLIREPFFVPETKSIRTLLQEFRARKQHIAIAL
DEYGGTSGLITIEDVLEEIVGDIEDEHDTPREEDIRPVGDNIYELTGRALLEDLEDMGVDLDSDEVDTIGGYLSMEAGHV
PAPGESFTLRGWTFTVLEADRKLILRLRMEPADSAASRQTAGQDTAQQDGEQGAGPEAAQDAAQDEASDDPAVAPRYETL
PGSLGAAAPLDDAAASPQAAVQAAEEILRSTPPPAAETGDDAPRPTESPRV
>Mature_371_residues
MDGGSEGHSTIWSRLSRLFGHDDQESLEKAILEARAEGEVEPDEESMLLGILRFNDLQVQDTMIPRTDIDCVPHDMPMAE
VAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDGEGKVSSLAGLIREPFFVPETKSIRTLLQEFRARKQHIAIAL
DEYGGTSGLITIEDVLEEIVGDIEDEHDTPREEDIRPVGDNIYELTGRALLEDLEDMGVDLDSDEVDTIGGYLSMEAGHV
PAPGESFTLRGWTFTVLEADRKLILRLRMEPADSAASRQTAGQDTAQQDGEQGAGPEAAQDAAQDEASDDPAVAPRYETL
PGSLGAAAPLDDAAASPQAAVQAAEEILRSTPPPAAETGDDAPRPTESPRV

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=199, Percent_Identity=34.1708542713568, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI40068049, Length=162, Percent_Identity=34.5679012345679, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786879, Length=265, Percent_Identity=37.7358490566038, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI87082033, Length=235, Percent_Identity=29.3617021276596, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI145693175, Length=257, Percent_Identity=25.2918287937743, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790664, Length=192, Percent_Identity=27.6041666666667, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788119, Length=226, Percent_Identity=29.646017699115, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 40165; Mature: 40165

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGGSEGHSTIWSRLSRLFGHDDQESLEKAILEARAEGEVEPDEESMLLGILRFNDLQVQ
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHEEHHHHCCCEEEH
DTMIPRTDIDCVPHDMPMAEVAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDGE
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCC
GKVSSLAGLIREPFFVPETKSIRTLLQEFRARKQHIAIALDEYGGTSGLITIEDVLEEIV
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHHHH
GDIEDEHDTPREEDIRPVGDNIYELTGRALLEDLEDMGVDLDSDEVDTIGGYLSMEAGHV
HHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEECCCCC
PAPGESFTLRGWTFTVLEADRKLILRLRMEPADSAASRQTAGQDTAQQDGEQGAGPEAAQ
CCCCCCEEECCEEEEEEHHCCCEEEHEECCCCCHHHHHHHCCCCHHHHCCCCCCCCHHHH
DAAQDEASDDPAVAPRYETLPGSLGAAAPLDDAAASPQAAVQAAEEILRSTPPPAAETGD
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
DAPRPTESPRV
CCCCCCCCCCC
>Mature Secondary Structure
MDGGSEGHSTIWSRLSRLFGHDDQESLEKAILEARAEGEVEPDEESMLLGILRFNDLQVQ
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHEEHHHHCCCEEEH
DTMIPRTDIDCVPHDMPMAEVAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDGE
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCC
GKVSSLAGLIREPFFVPETKSIRTLLQEFRARKQHIAIALDEYGGTSGLITIEDVLEEIV
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHHHH
GDIEDEHDTPREEDIRPVGDNIYELTGRALLEDLEDMGVDLDSDEVDTIGGYLSMEAGHV
HHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEECCCCC
PAPGESFTLRGWTFTVLEADRKLILRLRMEPADSAASRQTAGQDTAQQDGEQGAGPEAAQ
CCCCCCEEECCEEEEEEHHCCCEEEHEECCCCCHHHHHHHCCCCHHHHCCCCCCCCHHHH
DAAQDEASDDPAVAPRYETLPGSLGAAAPLDDAAASPQAAVQAAEEILRSTPPPAAETGD
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
DAPRPTESPRV
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]