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The map label for this gene is ilvH [H]

Identifier: 220905166

GI number: 220905166

Start: 2292639

End: 2293130

Strand: Direct

Name: ilvH [H]

Synonym: Ddes_1904

Alternate gene names: 220905166

Gene position: 2292639-2293130 (Clockwise)

Preceding gene: 220905165

Following gene: 220905167

Centisome position: 79.79

GC content: 53.66

Gene sequence:

>492_bases
ATGACCAAGACACATGTGCTTTCCGTGCTGGTGGAAAATGAACCCGGCGTGCTTTCCCGCGTGGCGGGGCTGTTCAGCGG
GCGCGGCTTCAACATCCATTCGCTCAATGTGGCCCCGGCCCTGGAAGAAGGCGTTTCGCACATGACCATCACAACAGAAG
GCGACAGCCTGATTTTAGAGCAGATAATGAAACAGCTGCATAAAATCGTGTCTGTCATCAAGGTGGTGGACTTTGCAGAC
ATTGCCGCTGTCGAACGCGAAATGATGCTTGTCAAGGTGCAGGCTGAAGGCCCCATGCGGGGTGAAATTCTGCGCACCGT
TGAAATATTCCGCTGCAAAGTGGTGGACGTAAGCCCCAATGAAATGACCATTGAGGCTACAGGCAATCAGGACAAGCTGG
ATGCCATCATCAATCTTTTACAGCGCTTCGGCATCAAGGAACTGGCGCGCACAGGCTCTGTGGCCATGCGTCGTTCCAAA
AAGGCGGATTAG

Upstream 100 bases:

>100_bases
GCCTTTATCGACGTAGTGGTTGAACGCGAGGAAAACGTGTACCCCATCGTGCCTGCCGGCGCGGCGCTTGATGAAATGTT
GCTGGTGTAAAGGAGGGGCT

Downstream 100 bases:

>100_bases
GGATTTTCACCCGTGAGCGGATTTTCATGAAAATATTTATCCGCTCTGCCGCCGCACACGTGCGATACGCCGCAACGCGG
CGTAAGTGCAGAAAACACGC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTKTHVLSVLVENEPGVLSRVAGLFSGRGFNIHSLNVAPALEEGVSHMTITTEGDSLILEQIMKQLHKIVSVIKVVDFAD
IAAVEREMMLVKVQAEGPMRGEILRTVEIFRCKVVDVSPNEMTIEATGNQDKLDAIINLLQRFGIKELARTGSVAMRRSK
KAD

Sequences:

>Translated_163_residues
MTKTHVLSVLVENEPGVLSRVAGLFSGRGFNIHSLNVAPALEEGVSHMTITTEGDSLILEQIMKQLHKIVSVIKVVDFAD
IAAVEREMMLVKVQAEGPMRGEILRTVEIFRCKVVDVSPNEMTIEATGNQDKLDAIINLLQRFGIKELARTGSVAMRRSK
KAD
>Mature_162_residues
TKTHVLSVLVENEPGVLSRVAGLFSGRGFNIHSLNVAPALEEGVSHMTITTEGDSLILEQIMKQLHKIVSVIKVVDFADI
AAVEREMMLVKVQAEGPMRGEILRTVEIFRCKVVDVSPNEMTIEATGNQDKLDAIINLLQRFGIKELARTGSVAMRRSKK
AD

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=158, Percent_Identity=50.6329113924051, Blast_Score=150, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6319837, Length=206, Percent_Identity=29.126213592233, Blast_Score=88, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 17939; Mature: 17808

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTHVLSVLVENEPGVLSRVAGLFSGRGFNIHSLNVAPALEEGVSHMTITTEGDSLILE
CCCHHEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCCHHHHCCCCEEEEEECCCHHHHH
QIMKQLHKIVSVIKVVDFADIAAVEREMMLVKVQAEGPMRGEILRTVEIFRCKVVDVSPN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHEEEHEEEEEEECCC
EMTIEATGNQDKLDAIINLLQRFGIKELARTGSVAMRRSKKAD
CEEEEECCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHCCCCC
>Mature Secondary Structure 
TKTHVLSVLVENEPGVLSRVAGLFSGRGFNIHSLNVAPALEEGVSHMTITTEGDSLILE
CCHHEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCCHHHHCCCCEEEEEECCCHHHHH
QIMKQLHKIVSVIKVVDFADIAAVEREMMLVKVQAEGPMRGEILRTVEIFRCKVVDVSPN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHEEEHEEEEEEECCC
EMTIEATGNQDKLDAIINLLQRFGIKELARTGSVAMRRSKKAD
CEEEEECCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]