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The map label for this gene is murA

Identifier: 220905108

GI number: 220905108

Start: 2225083

End: 2226336

Strand: Reverse

Name: murA

Synonym: Ddes_1845

Alternate gene names: 220905108

Gene position: 2226336-2225083 (Counterclockwise)

Preceding gene: 220905111

Following gene: 220905107

Centisome position: 77.48

GC content: 60.85

Gene sequence:

>1254_bases
ATGGACAAGTTGGTCATTGAGGGCGGTGTGCCGCTTACGGGCAGTATTGAGGTGAGCGGCTCAAAAAATGCTGCGCTGCC
TATCCTTTTTGCTGCAATTTTGCCTGAAGAGCCTGTTACTATTACCAATGTTCCTGATCTTCGCGATATTCACACCACCC
TCAACCTGCTCAAGGTGCTCGGTTGCGACTGCCAGTACGAAAACGGGCAGGTGCGTATCGTTCCGGGCAGTCTGCTGCCC
GAAGCCCCGTACGACCTTGTGCGCACCATGCGGGCATCGGTGCTTTGCCTGGGGCCTCTGCTTGCCCGCATAGGCCAGGC
CCGTGTGGCGCTGCCCGGCGGCTGCGCCATCGGCGCGCGCCCCGTGGACCAGCACTTGAAGGGGCTGGAGCAGATGGGCG
CGAGCTTTCAATTGGAAGAAGGCTATATCATCGGCCGCTGCCGCAAGCTCACGGGCGCGCACATCACGTTTGACATGCCC
ACGGTGGGCGGCACGGAAAACCTGCTCATGGCGGCTGTACTGGCCGAGGGCAAGACCGTGCTGGAAAACGTGGCTCTTGA
GCCTGAGGTGGTGGATCTTGCAAATTTCCTGTGCGCCTGCGGCGCGCGCATAAGCGGGCAGGGCACATCGTGCATACGTA
TTGAGGGCGTCACCTCCCTGCATCAGGCTACGTATCCCGTCATGCCGGACCGCATTGAAGCCGGAACATTTCTGGCGGCG
GCGGGCATTACAGGTGGCGAACTTCTTTTGCACAACTGCCCTTATGACGAGCTTGAGTCCGTTATCCTCAAACTGCGCAG
CATGGGGATGGAGATCACGCAGCAGGGCAGCGGCGTGCTGGCCCGCTGCTGCGCGGCCCCCCTGCGCGGCACGGACGTGA
AAACCCAGCCATACCCCGGCTTTCCTACAGACATGCAGGCCCAGATCATGGCGCTCATGTGCCTGGCGCAGGGGGCCAGC
GTGGTGGAAGAAAGCATTTTTGAAAACCGCTTCATGCATGTTCTTGAGCTGATGCGCATGGGCGCGCAGATCAAGGTTTC
GGGCCATACGGCCATGGTGCGCGGCGTACAGAAACTTACGGGCGCGCCTGTTATGGCATCAGACCTGCGGGCCAGTGCTT
CACTGGTGCTTGCGGGCCTTGCTGCCCAGGGCGTAACAGAGGTGCGGCGCATTTATCACCTGGACAGGGGCTACGAGCAT
ATCGAGCACAAGCTTAACGCCGTGGGCGCGCGCATCCGGCGGGAAAAGCAGTAA

Upstream 100 bases:

>100_bases
CACTGTCTGCCCGGCTGCTTTTCGTCCCTTTCGGGCAAGCCTGGTGACCGGGGCCGGATTTTCGCGGCCACAAGCATAAA
AAAATATTTCGGGGATATAT

Downstream 100 bases:

>100_bases
ACAGCCAAGGAGAAACCATGCAACGCCTGGCGCTTATTTTGCTTTTGTTCATGCTGGCCGGTCTTAACGGCTGCGCTTAC
AGCGGGTATGGCCTGTATGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDKLVIEGGVPLTGSIEVSGSKNAALPILFAAILPEEPVTITNVPDLRDIHTTLNLLKVLGCDCQYENGQVRIVPGSLLP
EAPYDLVRTMRASVLCLGPLLARIGQARVALPGGCAIGARPVDQHLKGLEQMGASFQLEEGYIIGRCRKLTGAHITFDMP
TVGGTENLLMAAVLAEGKTVLENVALEPEVVDLANFLCACGARISGQGTSCIRIEGVTSLHQATYPVMPDRIEAGTFLAA
AGITGGELLLHNCPYDELESVILKLRSMGMEITQQGSGVLARCCAAPLRGTDVKTQPYPGFPTDMQAQIMALMCLAQGAS
VVEESIFENRFMHVLELMRMGAQIKVSGHTAMVRGVQKLTGAPVMASDLRASASLVLAGLAAQGVTEVRRIYHLDRGYEH
IEHKLNAVGARIRREKQ

Sequences:

>Translated_417_residues
MDKLVIEGGVPLTGSIEVSGSKNAALPILFAAILPEEPVTITNVPDLRDIHTTLNLLKVLGCDCQYENGQVRIVPGSLLP
EAPYDLVRTMRASVLCLGPLLARIGQARVALPGGCAIGARPVDQHLKGLEQMGASFQLEEGYIIGRCRKLTGAHITFDMP
TVGGTENLLMAAVLAEGKTVLENVALEPEVVDLANFLCACGARISGQGTSCIRIEGVTSLHQATYPVMPDRIEAGTFLAA
AGITGGELLLHNCPYDELESVILKLRSMGMEITQQGSGVLARCCAAPLRGTDVKTQPYPGFPTDMQAQIMALMCLAQGAS
VVEESIFENRFMHVLELMRMGAQIKVSGHTAMVRGVQKLTGAPVMASDLRASASLVLAGLAAQGVTEVRRIYHLDRGYEH
IEHKLNAVGARIRREKQ
>Mature_417_residues
MDKLVIEGGVPLTGSIEVSGSKNAALPILFAAILPEEPVTITNVPDLRDIHTTLNLLKVLGCDCQYENGQVRIVPGSLLP
EAPYDLVRTMRASVLCLGPLLARIGQARVALPGGCAIGARPVDQHLKGLEQMGASFQLEEGYIIGRCRKLTGAHITFDMP
TVGGTENLLMAAVLAEGKTVLENVALEPEVVDLANFLCACGARISGQGTSCIRIEGVTSLHQATYPVMPDRIEAGTFLAA
AGITGGELLLHNCPYDELESVILKLRSMGMEITQQGSGVLARCCAAPLRGTDVKTQPYPGFPTDMQAQIMALMCLAQGAS
VVEESIFENRFMHVLELMRMGAQIKVSGHTAMVRGVQKLTGAPVMASDLRASASLVLAGLAAQGVTEVRRIYHLDRGYEH
IEHKLNAVGARIRREKQ

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=53.5885167464115, Blast_Score=430, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_DESDA (B8J283)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480420.1
- GeneID:   7285558
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1845
- HOGENOM:   HBG482701
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44569; Mature: 44569

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: ACT_SITE 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLVIEGGVPLTGSIEVSGSKNAALPILFAAILPEEPVTITNVPDLRDIHTTLNLLKVL
CCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHH
GCDCQYENGQVRIVPGSLLPEAPYDLVRTMRASVLCLGPLLARIGQARVALPGGCAIGAR
CCCCEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
PVDQHLKGLEQMGASFQLEEGYIIGRCRKLTGAHITFDMPTVGGTENLLMAAVLAEGKTV
CHHHHHHHHHHHCCCEEECCCEEEEEEHHCCCCEEEEECCCCCCCHHHHHHHHHHCCHHH
LENVALEPEVVDLANFLCACGARISGQGTSCIRIEGVTSLHQATYPVMPDRIEAGTFLAA
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCEEEE
AGITGGELLLHNCPYDELESVILKLRSMGMEITQQGSGVLARCCAAPLRGTDVKTQPYPG
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
FPTDMQAQIMALMCLAQGASVVEESIFENRFMHVLELMRMGAQIKVSGHTAMVRGVQKLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHC
GAPVMASDLRASASLVLAGLAAQGVTEVRRIYHLDRGYEHIEHKLNAVGARIRREKQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKLVIEGGVPLTGSIEVSGSKNAALPILFAAILPEEPVTITNVPDLRDIHTTLNLLKVL
CCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHH
GCDCQYENGQVRIVPGSLLPEAPYDLVRTMRASVLCLGPLLARIGQARVALPGGCAIGAR
CCCCEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
PVDQHLKGLEQMGASFQLEEGYIIGRCRKLTGAHITFDMPTVGGTENLLMAAVLAEGKTV
CHHHHHHHHHHHCCCEEECCCEEEEEEHHCCCCEEEEECCCCCCCHHHHHHHHHHCCHHH
LENVALEPEVVDLANFLCACGARISGQGTSCIRIEGVTSLHQATYPVMPDRIEAGTFLAA
HHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCEEEE
AGITGGELLLHNCPYDELESVILKLRSMGMEITQQGSGVLARCCAAPLRGTDVKTQPYPG
CCCCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
FPTDMQAQIMALMCLAQGASVVEESIFENRFMHVLELMRMGAQIKVSGHTAMVRGVQKLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHC
GAPVMASDLRASASLVLAGLAAQGVTEVRRIYHLDRGYEHIEHKLNAVGARIRREKQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA