Click here to switch to the map view.

The map label for this gene is gmhB [H]

Identifier: 220905100

GI number: 220905100

Start: 2218045

End: 2218650

Strand: Reverse

Name: gmhB [H]

Synonym: Ddes_1837

Alternate gene names: 220905100

Gene position: 2218650-2218045 (Counterclockwise)

Preceding gene: 220905101

Following gene: 220905098

Centisome position: 77.21

GC content: 63.37

Gene sequence:

>606_bases
ATGACGGAAAAAACGGCGTTGCGCCGGGCTATTTTTCTTGACCGCGACGGAACCCTGAACAGGGATACGGGCTATGTACA
CCGCAAGGAAGACTGGCAATGGCTGCCCGGCGTGCCCGAGGCGCTCAAACGTCTGCGCGCCGTGGGCTATGTGCTGGTGG
TGGTAAGCAACCAGTCGGGGATTGCGCGGGGCATGTTTGACCATGACGCCCTGAAGCGTCTGGAAGAATGGGTCAATGCC
GACCTTGCGGCCAAAAATGCCGCCATTGATGCATGGTACTATTGCCCGCACCTGCCTGAAATTACCGGCCCATGCCAGTG
CCGCAAGCCTGAGCCCGGGCTTCTTCTCCGGGCTGCCCGCGATCTGGATCTGGACCTTGCCAACTCGTGGATGATCGGCG
ACCGCGTGCGCGACGTGCGTGCCGGGCTGGCGGCGGGCTGCCGCAGCATTCTGCTGCATCCTGAAAGCGGCGGCCATGAG
GATGACGGGGACGTGCCGGACGGCGTGTCCGTAGCACCGCATCTGCCTGCGGCGGGGGTGCACATTCTGGCTCCGCGCAT
GCGTGAACTGCGCGCGGCCCGTCTGCTGGAAAAGATGAAGGAGTGA

Upstream 100 bases:

>100_bases
CGGTGGCCCAGGCTGCAGAAGAGGCCGCCACCCTGCGCGGTTACCAAAAGCAGAAATAGCGCCGGAATACGGCAGAGAAC
ACAGGGGCAGGAGCAGAATC

Downstream 100 bases:

>100_bases
GTCGGGCAGGGTTGCCTTGTCGCAAACAGGTCCGGCAAAAAGGGCGGCCCGTCACGGCAGGCTCCGCCGGTATGGCAGGC
TGCCGGCCGGATATGCTGTG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTEKTALRRAIFLDRDGTLNRDTGYVHRKEDWQWLPGVPEALKRLRAVGYVLVVVSNQSGIARGMFDHDALKRLEEWVNA
DLAAKNAAIDAWYYCPHLPEITGPCQCRKPEPGLLLRAARDLDLDLANSWMIGDRVRDVRAGLAAGCRSILLHPESGGHE
DDGDVPDGVSVAPHLPAAGVHILAPRMRELRAARLLEKMKE

Sequences:

>Translated_201_residues
MTEKTALRRAIFLDRDGTLNRDTGYVHRKEDWQWLPGVPEALKRLRAVGYVLVVVSNQSGIARGMFDHDALKRLEEWVNA
DLAAKNAAIDAWYYCPHLPEITGPCQCRKPEPGLLLRAARDLDLDLANSWMIGDRVRDVRAGLAAGCRSILLHPESGGHE
DDGDVPDGVSVAPHLPAAGVHILAPRMRELRAARLLEKMKE
>Mature_200_residues
TEKTALRRAIFLDRDGTLNRDTGYVHRKEDWQWLPGVPEALKRLRAVGYVLVVVSNQSGIARGMFDHDALKRLEEWVNAD
LAAKNAAIDAWYYCPHLPEITGPCQCRKPEPGLLLRAARDLDLDLANSWMIGDRVRDVRAGLAAGCRSILLHPESGGHED
DGDVPDGVSVAPHLPAAGVHILAPRMRELRAARLLEKMKE

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=148, Percent_Identity=45.945945945946, Blast_Score=144, Evalue=3e-36,
Organism=Escherichia coli, GI87082027, Length=136, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 22356; Mature: 22225

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKTALRRAIFLDRDGTLNRDTGYVHRKEDWQWLPGVPEALKRLRAVGYVLVVVSNQSG
CCCHHHHHHHHEECCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCC
IARGMFDHDALKRLEEWVNADLAAKNAAIDAWYYCPHLPEITGPCQCRKPEPGLLLRAAR
CHHCCCCHHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
DLDLDLANSWMIGDRVRDVRAGLAAGCRSILLHPESGGHEDDGDVPDGVSVAPHLPAAGV
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCH
HILAPRMRELRAARLLEKMKE
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEKTALRRAIFLDRDGTLNRDTGYVHRKEDWQWLPGVPEALKRLRAVGYVLVVVSNQSG
CCHHHHHHHHEECCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCC
IARGMFDHDALKRLEEWVNADLAAKNAAIDAWYYCPHLPEITGPCQCRKPEPGLLLRAAR
CHHCCCCHHHHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
DLDLDLANSWMIGDRVRDVRAGLAAGCRSILLHPESGGHEDDGDVPDGVSVAPHLPAAGV
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCH
HILAPRMRELRAARLLEKMKE
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]