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The map label for this gene is mdtJ [H]

Identifier: 220905075

GI number: 220905075

Start: 2186578

End: 2187012

Strand: Direct

Name: mdtJ [H]

Synonym: Ddes_1812

Alternate gene names: 220905075

Gene position: 2186578-2187012 (Clockwise)

Preceding gene: 220905074

Following gene: 220905076

Centisome position: 76.1

GC content: 60.92

Gene sequence:

>435_bases
ATGCTTGAGACCAAACCCTATCACTGGCTCTGCCTCATGGGGGCCATCATTTTTGAAGTGGCCGGAACCACAGTCATGAA
GATGGCCCAGGGCTGGGGCTTCGCCCATGCAGCCATGCTGGGCCTTGTACTCATGTGGCTGGCTATCGCTCTTTCCTATT
ACATGCTGGCAAAAGCCACCACCGGCCTGCCCGTGGGCGTTGCTTTTGCCTTTTGGGAAGGCCTGGGCCTGACCTTCATC
ACCATATGCAGCGTGCTGCTGCTCGGCGAAAGCATGACCGTGACACGCGGCCTCGGCCTTGTCTGCGTGCTGGCCGGAGC
CTTGCTGGTACACCACGGCACAGGGCACGGCAAAGAAGACATACACCCGGCTGCCCGCCCCACGTCCAGCCTGAATGCGG
GCGGCAATGCCGCTGGTGAACGGGGGAACGCATAA

Upstream 100 bases:

>100_bases
CTGCAAAAACTGTCTGATGCATGGCCCCTGCGGGCGGCCAGGGCTTTTTCTGTTTCAAAATCGGGCTGAGGCATCAGTCT
GACAGCGCAGCGAGGATACA

Downstream 100 bases:

>100_bases
TGCAGCCCCTTACCTCTTTTTTCAGCCTCTCCCTTTTACTGGTGGTGATGGCGGCGGCACTGGACGTACTGGCAAACCTG
CTGCTGGCAAAATCCGGCGG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLETKPYHWLCLMGAIIFEVAGTTVMKMAQGWGFAHAAMLGLVLMWLAIALSYYMLAKATTGLPVGVAFAFWEGLGLTFI
TICSVLLLGESMTVTRGLGLVCVLAGALLVHHGTGHGKEDIHPAARPTSSLNAGGNAAGERGNA

Sequences:

>Translated_144_residues
MLETKPYHWLCLMGAIIFEVAGTTVMKMAQGWGFAHAAMLGLVLMWLAIALSYYMLAKATTGLPVGVAFAFWEGLGLTFI
TICSVLLLGESMTVTRGLGLVCVLAGALLVHHGTGHGKEDIHPAARPTSSLNAGGNAAGERGNA
>Mature_144_residues
MLETKPYHWLCLMGAIIFEVAGTTVMKMAQGWGFAHAAMLGLVLMWLAIALSYYMLAKATTGLPVGVAFAFWEGLGLTFI
TICSVLLLGESMTVTRGLGLVCVLAGALLVHHGTGHGKEDIHPAARPTSSLNAGGNAAGERGNA

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=127, Percent_Identity=37.007874015748, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 15057; Mature: 15057

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETKPYHWLCLMGAIIFEVAGTTVMKMAQGWGFAHAAMLGLVLMWLAIALSYYMLAKAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGLPVGVAFAFWEGLGLTFITICSVLLLGESMTVTRGLGLVCVLAGALLVHHGTGHGKED
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IHPAARPTSSLNAGGNAAGERGNA
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLETKPYHWLCLMGAIIFEVAGTTVMKMAQGWGFAHAAMLGLVLMWLAIALSYYMLAKAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGLPVGVAFAFWEGLGLTFITICSVLLLGESMTVTRGLGLVCVLAGALLVHHGTGHGKED
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IHPAARPTSSLNAGGNAAGERGNA
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA