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The map label for this gene is glmM

Identifier: 220904977

GI number: 220904977

Start: 2071735

End: 2073087

Strand: Reverse

Name: glmM

Synonym: Ddes_1713

Alternate gene names: 220904977

Gene position: 2073087-2071735 (Counterclockwise)

Preceding gene: 220904978

Following gene: 220904976

Centisome position: 72.15

GC content: 61.57

Gene sequence:

>1353_bases
ATGGCCGATCGTCTTTTCGGCACGGATGGTTTGCGTGGCACGGTGAATACATACCCGATGACGGTGGACGTTGCCCTGCG
TCTGGGGCTGGCCGCAGGGATTCGTTTCCGGCGGGGTCAGCATCAGCATAAAGTGGTTATCGGCAAGGACACGCGCCTGT
CGGGGTATATGTTTGAGTCCGCCCTCACGGCGGGGCTGTGCGCTGCGGGTATGCACGTCATCATGACAGGTCCGTTGCCT
ACCCCGGCCATATCTTTTCTGACGCGCAGCATGCGTGCGGATCTGGGTGTGGTTATTTCGGCCTCGCACAATCCCTTTCA
GGACAACGGCATAAAGTTTTTTGATGCCGACGGGTACAAGCTGCCCGATATGGCCGAAGACGAGATCGCGGCCATGGTGC
TGGATGCCGGTTTTTCCTGGCCGTATCCCGATTCGCGCGGCGTGGGCCGTGCCACAAAGATTGAAGACGCGGGCGGGCGC
TACATTGTCTACACCAAAAACTGCTTTCCTGCCCACCTGACCCTTTCAGGCCTGCGCATTGTGGTGGACTGTGCCAACGG
GGCAAGCTACAAGGTGGCTCCCCTTGCTCTGGAAGAGCTTGGGGCTGAAGTATTCCGCATCGGGACCGGCCCTGACGGAA
CCAATATCAACGAGCACTGCGGCTCGCTGCATCCTGACGTGGTCGCGGCCAAGGTGCGCGAGGTGCGGGCCGACATCGGC
CTGGCCCTGGATGGCGATGCCGACCGCCTTATCGTGGTGGACGAGCGCGGGGTAGTTCTGGACGGCGACCAGATCATGGC
CCTGTGTGCCCAGGCCATGATGGCCAGGGGCGAACTGCCCGGCAACCTGCTGGTAGCCACGGCCATGAGCAACATGGCTC
TGGAACTTTTCATGCGCGATCACGGCGGTCAGCTTTTGCGCACCAAGGTGGGCGACCGTTACGTCATGGAGGCCATGCGC
CGTGAAGGAGCCATGCTCGGCGGTGAACAGTCGGGGCATCTTATTTTCCACCGTTACAGCACCACGGGTGACGGACTGCT
GGCCGCGCTGCAGATATTGCGTATCATGCGGGAAAAAGAGCGGCCGCTTTCTGAACTGGCCGGGCTGCTGACGCCCTTTC
CGCAAAAGCTCATCAACGTGCGGGTGGAAAAGCGCCTGCCCTTTGAGGAGCGCCCCGCCATTGGTGAAGCCGTGGCCCAG
GTGGAAAAAGAACTGGGCGGCCGTGGGCGGGTACTTTTGCGCTATTCCGGCACCGAGGCCCTGTGCCGCGTCATGGTGGA
AGGCGAGCATGAAGACAGGGTGCGGACCTACGCCGAAGACCTGGCCCAGGTGGTGGAGCGGGAACTGCGTTAA

Upstream 100 bases:

>100_bases
CCGGCACAGAAGAAGTTACGGTAAGCCGCAAGAAAAAATAGCCCGTACTCCCGGCAAGTTGCGGGAAACGGAGGGCGCTT
TTGCCCTTGAAGGAGATGGC

Downstream 100 bases:

>100_bases
GCTCCTTGCGGACATCCGGTTTTTGAACGAGACTACAGACAAGCAAAGCAACAGCGGAGGCGAGCATGAAGGATATTCGC
AAGGTTATTATTCCCGTGGC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MADRLFGTDGLRGTVNTYPMTVDVALRLGLAAGIRFRRGQHQHKVVIGKDTRLSGYMFESALTAGLCAAGMHVIMTGPLP
TPAISFLTRSMRADLGVVISASHNPFQDNGIKFFDADGYKLPDMAEDEIAAMVLDAGFSWPYPDSRGVGRATKIEDAGGR
YIVYTKNCFPAHLTLSGLRIVVDCANGASYKVAPLALEELGAEVFRIGTGPDGTNINEHCGSLHPDVVAAKVREVRADIG
LALDGDADRLIVVDERGVVLDGDQIMALCAQAMMARGELPGNLLVATAMSNMALELFMRDHGGQLLRTKVGDRYVMEAMR
REGAMLGGEQSGHLIFHRYSTTGDGLLAALQILRIMREKERPLSELAGLLTPFPQKLINVRVEKRLPFEERPAIGEAVAQ
VEKELGGRGRVLLRYSGTEALCRVMVEGEHEDRVRTYAEDLAQVVERELR

Sequences:

>Translated_450_residues
MADRLFGTDGLRGTVNTYPMTVDVALRLGLAAGIRFRRGQHQHKVVIGKDTRLSGYMFESALTAGLCAAGMHVIMTGPLP
TPAISFLTRSMRADLGVVISASHNPFQDNGIKFFDADGYKLPDMAEDEIAAMVLDAGFSWPYPDSRGVGRATKIEDAGGR
YIVYTKNCFPAHLTLSGLRIVVDCANGASYKVAPLALEELGAEVFRIGTGPDGTNINEHCGSLHPDVVAAKVREVRADIG
LALDGDADRLIVVDERGVVLDGDQIMALCAQAMMARGELPGNLLVATAMSNMALELFMRDHGGQLLRTKVGDRYVMEAMR
REGAMLGGEQSGHLIFHRYSTTGDGLLAALQILRIMREKERPLSELAGLLTPFPQKLINVRVEKRLPFEERPAIGEAVAQ
VEKELGGRGRVLLRYSGTEALCRVMVEGEHEDRVRTYAEDLAQVVERELR
>Mature_449_residues
ADRLFGTDGLRGTVNTYPMTVDVALRLGLAAGIRFRRGQHQHKVVIGKDTRLSGYMFESALTAGLCAAGMHVIMTGPLPT
PAISFLTRSMRADLGVVISASHNPFQDNGIKFFDADGYKLPDMAEDEIAAMVLDAGFSWPYPDSRGVGRATKIEDAGGRY
IVYTKNCFPAHLTLSGLRIVVDCANGASYKVAPLALEELGAEVFRIGTGPDGTNINEHCGSLHPDVVAAKVREVRADIGL
ALDGDADRLIVVDERGVVLDGDQIMALCAQAMMARGELPGNLLVATAMSNMALELFMRDHGGQLLRTKVGDRYVMEAMRR
EGAMLGGEQSGHLIFHRYSTTGDGLLAALQILRIMREKERPLSELAGLLTPFPQKLINVRVEKRLPFEERPAIGEAVAQV
EKELGGRGRVLLRYSGTEALCRVMVEGEHEDRVRTYAEDLAQVVERELR

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=50.1123595505618, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=26.7123287671233, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_DESDA (B8J1K3)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480289.1
- ProteinModelPortal:   B8J1K3
- GeneID:   7285424
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1713
- HOGENOM:   HBG644964
- ProtClustDB:   PRK14314
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49047; Mature: 48916

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRLFGTDGLRGTVNTYPMTVDVALRLGLAAGIRFRRGQHQHKVVIGKDTRLSGYMFES
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCHHHCCCCCCCEEEEECCCCCCHHHHHH
ALTAGLCAAGMHVIMTGPLPTPAISFLTRSMRADLGVVISASHNPFQDNGIKFFDADGYK
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCC
LPDMAEDEIAAMVLDAGFSWPYPDSRGVGRATKIEDAGGRYIVYTKNCFPAHLTLSGLRI
CCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCEEEECCEEE
VVDCANGASYKVAPLALEELGAEVFRIGTGPDGTNINEHCGSLHPDVVAAKVREVRADIG
EEECCCCCCEEEHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCC
LALDGDADRLIVVDERGVVLDGDQIMALCAQAMMARGELPGNLLVATAMSNMALELFMRD
EEEECCCCEEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHEEEEEHH
HGGQLLRTKVGDRYVMEAMRREGAMLGGEQSGHLIFHRYSTTGDGLLAALQILRIMREKE
CCCCEEEHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
RPLSELAGLLTPFPQKLINVRVEKRLPFEERPAIGEAVAQVEKELGGRGRVLLRYSGTEA
CCHHHHHHHHCCCHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHH
LCRVMVEGEHEDRVRTYAEDLAQVVERELR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADRLFGTDGLRGTVNTYPMTVDVALRLGLAAGIRFRRGQHQHKVVIGKDTRLSGYMFES
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCHHHCCCCCCCEEEEECCCCCCHHHHHH
ALTAGLCAAGMHVIMTGPLPTPAISFLTRSMRADLGVVISASHNPFQDNGIKFFDADGYK
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCC
LPDMAEDEIAAMVLDAGFSWPYPDSRGVGRATKIEDAGGRYIVYTKNCFPAHLTLSGLRI
CCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCEEEECCEEE
VVDCANGASYKVAPLALEELGAEVFRIGTGPDGTNINEHCGSLHPDVVAAKVREVRADIG
EEECCCCCCEEEHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCC
LALDGDADRLIVVDERGVVLDGDQIMALCAQAMMARGELPGNLLVATAMSNMALELFMRD
EEEECCCCEEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHEEEEEHH
HGGQLLRTKVGDRYVMEAMRREGAMLGGEQSGHLIFHRYSTTGDGLLAALQILRIMREKE
CCCCEEEHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
RPLSELAGLLTPFPQKLINVRVEKRLPFEERPAIGEAVAQVEKELGGRGRVLLRYSGTEA
CCHHHHHHHHCCCHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHH
LCRVMVEGEHEDRVRTYAEDLAQVVERELR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA