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The map label for this gene is gtaB [H]

Identifier: 220904976

GI number: 220904976

Start: 2070797

End: 2071669

Strand: Reverse

Name: gtaB [H]

Synonym: Ddes_1712

Alternate gene names: 220904976

Gene position: 2071669-2070797 (Counterclockwise)

Preceding gene: 220904977

Following gene: 220904975

Centisome position: 72.1

GC content: 52.35

Gene sequence:

>873_bases
ATGAAGGATATTCGCAAGGTTATTATTCCCGTGGCCGGATGGGGTACGCGTTCATTACCCGCGACCAAGAATATTCCCAA
GGAAATGCTGCCCATCTACAACAAGCCGGTCATCCAGTATGTGGTGGAAGAGGCCCAGAAGGCCAATATCCAGGACGTTA
TTTTTGTAACCAACCGCGACAAAAGCGTCATTGAAGACCACTTTGACTATAACCTGCAACTGGAAGCTGTGCTTGAACGC
GCCGGAAAGCTCGACAAGCTGCAAGAAGTGCGCAAGGTAGCGGAAATGGTCAACATCATGTCCGTGCGCCAGAAAAAACA
GCTCGGTCTCGGGCATGCCGTGCTGTGTGCGCGTGAACTGGTACGGGACGATCCTTTTGCCGTTATGGTGGGTGATGACC
TGATGTTTGGCGGTGTTCCCGGCATTGCCCAGCTTATTGACGTGGCCATGGCTGAAAAGATGCCCGTCATCGGCGTTATG
GAAGTGCCATGGGAAAAGGTAGACCGTTACGGCATCATTGAAGGGGACGAAGTTGCTCCCGGAGTATTCAGGGTCAAGAG
TATGGTGGAAAAGCCCGCCCGTGACAAGGCCCCCTCGCGCATGGCTATTGTGGGCCGTTATGTGCTTACACCCGATATTT
TTGACTATCTTGAAAAAGTCACTCCAGGGCACGGCGGCGAAATTCAACTGACTGACGCTCTTCAGGCCATGGCGCAGGAC
AGGGGCATGATGGCGGTGCGCATGTCGGGCATGCGTTTTGACGCCGGAGACTGGGCGGAATTTTTGACGGCCAATATCTA
TTTTGCCCTGCAGGACGAAGAATTGCGCTATGATTTGTTGAATTTGCTCAAGAATTTTGTGCAATTCCACTAG

Upstream 100 bases:

>100_bases
ACCTGGCCCAGGTGGTGGAGCGGGAACTGCGTTAAGCTCCTTGCGGACATCCGGTTTTTGAACGAGACTACAGACAAGCA
AAGCAACAGCGGAGGCGAGC

Downstream 100 bases:

>100_bases
GAATCGCGGTTAACGACATTTGGCCTGCTGAGCAGTTTCAGAGGCCCGTTTCAGGCTGTCTGCGCGTTTATGCCGCCGGG
CTGAAACGGGCCTTTCTTGT

Product: Nucleotidyl transferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKDIRKVIIPVAGWGTRSLPATKNIPKEMLPIYNKPVIQYVVEEAQKANIQDVIFVTNRDKSVIEDHFDYNLQLEAVLER
AGKLDKLQEVRKVAEMVNIMSVRQKKQLGLGHAVLCARELVRDDPFAVMVGDDLMFGGVPGIAQLIDVAMAEKMPVIGVM
EVPWEKVDRYGIIEGDEVAPGVFRVKSMVEKPARDKAPSRMAIVGRYVLTPDIFDYLEKVTPGHGGEIQLTDALQAMAQD
RGMMAVRMSGMRFDAGDWAEFLTANIYFALQDEELRYDLLNLLKNFVQFH

Sequences:

>Translated_290_residues
MKDIRKVIIPVAGWGTRSLPATKNIPKEMLPIYNKPVIQYVVEEAQKANIQDVIFVTNRDKSVIEDHFDYNLQLEAVLER
AGKLDKLQEVRKVAEMVNIMSVRQKKQLGLGHAVLCARELVRDDPFAVMVGDDLMFGGVPGIAQLIDVAMAEKMPVIGVM
EVPWEKVDRYGIIEGDEVAPGVFRVKSMVEKPARDKAPSRMAIVGRYVLTPDIFDYLEKVTPGHGGEIQLTDALQAMAQD
RGMMAVRMSGMRFDAGDWAEFLTANIYFALQDEELRYDLLNLLKNFVQFH
>Mature_290_residues
MKDIRKVIIPVAGWGTRSLPATKNIPKEMLPIYNKPVIQYVVEEAQKANIQDVIFVTNRDKSVIEDHFDYNLQLEAVLER
AGKLDKLQEVRKVAEMVNIMSVRQKKQLGLGHAVLCARELVRDDPFAVMVGDDLMFGGVPGIAQLIDVAMAEKMPVIGVM
EVPWEKVDRYGIIEGDEVAPGVFRVKSMVEKPARDKAPSRMAIVGRYVLTPDIFDYLEKVTPGHGGEIQLTDALQAMAQD
RGMMAVRMSGMRFDAGDWAEFLTANIYFALQDEELRYDLLNLLKNFVQFH

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a mem

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=279, Percent_Identity=42.6523297491039, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788355, Length=285, Percent_Identity=37.1929824561403, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790224, Length=274, Percent_Identity=26.2773722627737, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788351, Length=278, Percent_Identity=24.8201438848921, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32696; Mature: 32696

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIRKVIIPVAGWGTRSLPATKNIPKEMLPIYNKPVIQYVVEEAQKANIQDVIFVTNRD
CCCHHHHEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCC
KSVIEDHFDYNLQLEAVLERAGKLDKLQEVRKVAEMVNIMSVRQKKQLGLGHAVLCAREL
HHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VRDDPFAVMVGDDLMFGGVPGIAQLIDVAMAEKMPVIGVMEVPWEKVDRYGIIEGDEVAP
HCCCCEEEEECCCEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCCCCCCCC
GVFRVKSMVEKPARDKAPSRMAIVGRYVLTPDIFDYLEKVTPGHGGEIQLTDALQAMAQD
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHC
RGMMAVRMSGMRFDAGDWAEFLTANIYFALQDEELRYDLLNLLKNFVQFH
CCEEEEEECCCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDIRKVIIPVAGWGTRSLPATKNIPKEMLPIYNKPVIQYVVEEAQKANIQDVIFVTNRD
CCCHHHHEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCC
KSVIEDHFDYNLQLEAVLERAGKLDKLQEVRKVAEMVNIMSVRQKKQLGLGHAVLCAREL
HHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VRDDPFAVMVGDDLMFGGVPGIAQLIDVAMAEKMPVIGVMEVPWEKVDRYGIIEGDEVAP
HCCCCEEEEECCCEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCCCCCCCC
GVFRVKSMVEKPARDKAPSRMAIVGRYVLTPDIFDYLEKVTPGHGGEIQLTDALQAMAQD
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHC
RGMMAVRMSGMRFDAGDWAEFLTANIYFALQDEELRYDLLNLLKNFVQFH
CCEEEEEECCCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA