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The map label for this gene is 220904954

Identifier: 220904954

GI number: 220904954

Start: 2034668

End: 2035675

Strand: Direct

Name: 220904954

Synonym: Ddes_1690

Alternate gene names: NA

Gene position: 2034668-2035675 (Clockwise)

Preceding gene: 220904953

Following gene: 220904955

Centisome position: 70.81

GC content: 56.35

Gene sequence:

>1008_bases
ATGAACCTATCCCAAATGATCCAGACTATCGATACGCACACGGCCGGCAACCCCACGCGCAACGTGGTTGCCGGGTGCCC
CGCCATAGCGGGAAACAGCATGCAGGAAAAAATGGCTTACGCCAGTAAGCACCTCGACCGGCTTATCGGCTCTCTTATGC
TTGAGCCGCGGGGACACAGCAATATGTCGGGCACGATATGGGTGCCCCCCTGCAATCCGGAAGCCCACATGGGCATACTG
TTTATTGATGCCGGAGGACTCATGCCCATGTGCGGGCACAGCACCATCGGCTGCGTCACCGCCATGCTCGAAACCGGCGC
GATCCCCCCTGAAGGTGATGTGTGCAACGTCAATATAGACACACCAGCAGGCCTTGTACGCACCAGGGCTGAAATCAGGG
ACGGCAAGGTGCTTCGTGTAACCTTTCGCAATGTGCCGTCCTTTCTCTTCTGTTCAGGCACCGTGGAAGTTCCCGGCACA
GGTGAAGTTCCCTATGACGTAGCCTACGGCGGCAATACCTATGCCATTGCCGATGCGAAGTATTTTTCCGGTCTGGATCT
GCGCTCCGGACACCGCGCGGCCATTGAAAAAGCCGCTCAGGCTTTTGGTGGTGCAGTACGCAAGGCCGTGGACTTCAAGC
ATCCCGAAAAACCATTCATCAATATCATTACGCACGTGATGTTCTACACCCGGCCGGATGATCCCAAAGCCACCTATCGT
AATACCGTGGTATTTTTGCCTGATTCCCTTGATCGTTCCCCCTGCGGAACGGGAACCTCTGCCCGTGTTGCCTCGCTTTT
TGCCAAGGGTGACCTGGAGCTGAACCAGGAATTTATACACGAAAGCGTCATCGGCACACAGTTTACAGCCAGAATTGTGG
AGCCAGCCACTGTCGGCCCATGCAAGGGCGGCATACCCGAAGTCAGTGGCACGGCCTACCTCACAGGCTTTCACCAGTTT
GTCATTGACCCGGGTGACGCTCTCAAGCACGGATTCCGGCTGGACTAG

Upstream 100 bases:

>100_bases
AGACCATTTTCATCAACCTGGACAGATAGTCGCATACCTGCCTGCGGGCCGTCCCGTCCAAAAACGGGGCGGCCCGGCTT
TCAGCAACGAGGAAGACGCC

Downstream 100 bases:

>100_bases
GCTTTGCCGCCAGTAAGATACCGTGCGTTTCCATGCCATTTCATTGAAGACCGCTGCTTTTTCTGGAGTCACGCCGTTTC
ACAGCATGTTGCACAAGTGT

Product: proline racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNLSQMIQTIDTHTAGNPTRNVVAGCPAIAGNSMQEKMAYASKHLDRLIGSLMLEPRGHSNMSGTIWVPPCNPEAHMGIL
FIDAGGLMPMCGHSTIGCVTAMLETGAIPPEGDVCNVNIDTPAGLVRTRAEIRDGKVLRVTFRNVPSFLFCSGTVEVPGT
GEVPYDVAYGGNTYAIADAKYFSGLDLRSGHRAAIEKAAQAFGGAVRKAVDFKHPEKPFINIITHVMFYTRPDDPKATYR
NTVVFLPDSLDRSPCGTGTSARVASLFAKGDLELNQEFIHESVIGTQFTARIVEPATVGPCKGGIPEVSGTAYLTGFHQF
VIDPGDALKHGFRLD

Sequences:

>Translated_335_residues
MNLSQMIQTIDTHTAGNPTRNVVAGCPAIAGNSMQEKMAYASKHLDRLIGSLMLEPRGHSNMSGTIWVPPCNPEAHMGIL
FIDAGGLMPMCGHSTIGCVTAMLETGAIPPEGDVCNVNIDTPAGLVRTRAEIRDGKVLRVTFRNVPSFLFCSGTVEVPGT
GEVPYDVAYGGNTYAIADAKYFSGLDLRSGHRAAIEKAAQAFGGAVRKAVDFKHPEKPFINIITHVMFYTRPDDPKATYR
NTVVFLPDSLDRSPCGTGTSARVASLFAKGDLELNQEFIHESVIGTQFTARIVEPATVGPCKGGIPEVSGTAYLTGFHQF
VIDPGDALKHGFRLD
>Mature_335_residues
MNLSQMIQTIDTHTAGNPTRNVVAGCPAIAGNSMQEKMAYASKHLDRLIGSLMLEPRGHSNMSGTIWVPPCNPEAHMGIL
FIDAGGLMPMCGHSTIGCVTAMLETGAIPPEGDVCNVNIDTPAGLVRTRAEIRDGKVLRVTFRNVPSFLFCSGTVEVPGT
GEVPYDVAYGGNTYAIADAKYFSGLDLRSGHRAAIEKAAQAFGGAVRKAVDFKHPEKPFINIITHVMFYTRPDDPKATYR
NTVVFLPDSLDRSPCGTGTSARVASLFAKGDLELNQEFIHESVIGTQFTARIVEPATVGPCKGGIPEVSGTAYLTGFHQF
VIDPGDALKHGFRLD

Specific function: Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways [H]

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=336, Percent_Identity=37.797619047619, Blast_Score=202, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: =5.1.1.4 [H]

Molecular weight: Translated: 35896; Mature: 35896

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSQMIQTIDTHTAGNPTRNVVAGCPAIAGNSMQEKMAYASKHLDRLIGSLMLEPRGHS
CCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCC
NMSGTIWVPPCNPEAHMGILFIDAGGLMPMCGHSTIGCVTAMLETGAIPPEGDVCNVNID
CCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECC
TPAGLVRTRAEIRDGKVLRVTFRNVPSFLFCSGTVEVPGTGEVPYDVAYGGNTYAIADAK
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEECCEEECCCCCCCCEEEEECCCEEEEECCH
YFSGLDLRSGHRAAIEKAAQAFGGAVRKAVDFKHPEKPFINIITHVMFYTRPDDPKATYR
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCHHHC
NTVVFLPDSLDRSPCGTGTSARVASLFAKGDLELNQEFIHESVIGTQFTARIVEPATVGP
CEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHEEECCCCCCC
CKGGIPEVSGTAYLTGFHQFVIDPGDALKHGFRLD
CCCCCCCCCCCEEEEEEEEEEECCCHHHHCCCCCC
>Mature Secondary Structure
MNLSQMIQTIDTHTAGNPTRNVVAGCPAIAGNSMQEKMAYASKHLDRLIGSLMLEPRGHS
CCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCC
NMSGTIWVPPCNPEAHMGILFIDAGGLMPMCGHSTIGCVTAMLETGAIPPEGDVCNVNID
CCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECC
TPAGLVRTRAEIRDGKVLRVTFRNVPSFLFCSGTVEVPGTGEVPYDVAYGGNTYAIADAK
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEECCEEECCCCCCCCEEEEECCCEEEEECCH
YFSGLDLRSGHRAAIEKAAQAFGGAVRKAVDFKHPEKPFINIITHVMFYTRPDDPKATYR
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCHHHC
NTVVFLPDSLDRSPCGTGTSARVASLFAKGDLELNQEFIHESVIGTQFTARIVEPATVGP
CEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHEEECCCCCCC
CKGGIPEVSGTAYLTGFHQFVIDPGDALKHGFRLD
CCCCCCCCCCCEEEEEEEEEEECCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA