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The map label for this gene is kdpE [H]

Identifier: 220904946

GI number: 220904946

Start: 2023476

End: 2024219

Strand: Direct

Name: kdpE [H]

Synonym: Ddes_1681

Alternate gene names: 220904946

Gene position: 2023476-2024219 (Clockwise)

Preceding gene: 220904945

Following gene: 220904947

Centisome position: 70.42

GC content: 61.16

Gene sequence:

>744_bases
ATGACGCCATATCCCGAACAGCAGGACGTCAGCGCCCCGGAACGCATCCTCGTGATCGAGGATGACAAGGCCATACGCGC
CCTTGTGACAGCGGCCCTTGAAAGCCGCGCCATGGCCTGCATAACCGCAGGCACAGGACGTGAGGCCATTGCGGAAGCGT
CCCGCGCCGGGCCTGACGTCATACTGCTGGACCTGGGCCTGCCCGATATGGACGGCACAGATATTATCCGCACGGTGCGT
CAGTGGTCTATGGTTCCGATCATTGTGCTCAGCGCCCGCAGCGAGGATGATGACAAGGTTGCGGCGCTGGACGCCGGGGC
GGACGACTATCTGACCAAACCTTTCAGCATTGACGAACTGCTGGCCCGGCTGCGTGCAGCCCTGCGGCGCGGACGCTATG
AGCGCGGCAACCCGGACCGTGATGCCAGCTTCTTTGAAAACGGCCCCCTGCGCATAGACTTTGCCGCAGGCAGCGCAAGC
GTGAACGGCCAGGAAATCCATCTTGCGCCAATGGAGTACAAGCTGCTTTGCCTGCTGGCGCGCAATGCGGGCAAGGTGCT
TACACACAAAACTATCCTGCAGGCCGTATGGGGCAGTTCGCTGCCGCAAAACCTGCCCTCGCTGCGCGTATTCATGGCAA
CACTGCGCAAAAAACTGGAAAACGCCGCCCCCAGATGCGACTACATACACACTCATGTGGGTGTGGGCTATCGCATGGCC
CGCCTTGGCGAAACAGAGAGCTGA

Upstream 100 bases:

>100_bases
CGGTATTTTCCCTGGATCTGCAACGCGAAATTGAAGAAGGACCGGTGCCGGAGTCTCTTCGTGAAACTCCGCCCACCGGG
ACCGGCGCACGGGAGTAACC

Downstream 100 bases:

>100_bases
GCGTCGCGCAAACCGGCAGGCCCAATTTACCGCACGTTAACTATAGTCGCTTTATCTGTCAGTCTTTTCGGTAAAGTCCG
TATTTGCGCATCTTGCGGTA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTPYPEQQDVSAPERILVIEDDKAIRALVTAALESRAMACITAGTGREAIAEASRAGPDVILLDLGLPDMDGTDIIRTVR
QWSMVPIIVLSARSEDDDKVAALDAGADDYLTKPFSIDELLARLRAALRRGRYERGNPDRDASFFENGPLRIDFAAGSAS
VNGQEIHLAPMEYKLLCLLARNAGKVLTHKTILQAVWGSSLPQNLPSLRVFMATLRKKLENAAPRCDYIHTHVGVGYRMA
RLGETES

Sequences:

>Translated_247_residues
MTPYPEQQDVSAPERILVIEDDKAIRALVTAALESRAMACITAGTGREAIAEASRAGPDVILLDLGLPDMDGTDIIRTVR
QWSMVPIIVLSARSEDDDKVAALDAGADDYLTKPFSIDELLARLRAALRRGRYERGNPDRDASFFENGPLRIDFAAGSAS
VNGQEIHLAPMEYKLLCLLARNAGKVLTHKTILQAVWGSSLPQNLPSLRVFMATLRKKLENAAPRCDYIHTHVGVGYRMA
RLGETES
>Mature_246_residues
TPYPEQQDVSAPERILVIEDDKAIRALVTAALESRAMACITAGTGREAIAEASRAGPDVILLDLGLPDMDGTDIIRTVRQ
WSMVPIIVLSARSEDDDKVAALDAGADDYLTKPFSIDELLARLRAALRRGRYERGNPDRDASFFENGPLRIDFAAGSASV
NGQEIHLAPMEYKLLCLLARNAGKVLTHKTILQAVWGSSLPQNLPSLRVFMATLRKKLENAAPRCDYIHTHVGVGYRMAR
LGETES

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=48.2142857142857, Blast_Score=204, Evalue=3e-54,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=33.0357142857143, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=35.8744394618834, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.9285714285714, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=32.7510917030568, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=35.3711790393013, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.0175438596491, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=32.5991189427313, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.0396475770925, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=31.0043668122271, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=29.7777777777778, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=28.0172413793103, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=26.2008733624454, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790299, Length=135, Percent_Identity=34.8148148148148, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=31.6239316239316, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=33.0578512396694, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI145693157, Length=121, Percent_Identity=31.404958677686, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=31.5789473684211, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27056; Mature: 26925

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPYPEQQDVSAPERILVIEDDKAIRALVTAALESRAMACITAGTGREAIAEASRAGPDV
CCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCE
ILLDLGLPDMDGTDIIRTVRQWSMVPIIVLSARSEDDDKVAALDAGADDYLTKPFSIDEL
EEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCHHHCCCCCCHHHH
LARLRAALRRGRYERGNPDRDASFFENGPLRIDFAAGSASVNGQEIHLAPMEYKLLCLLA
HHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCEEEECCCCCEEHEEEC
RNAGKVLTHKTILQAVWGSSLPQNLPSLRVFMATLRKKLENAAPRCDYIHTHVGVGYRMA
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
RLGETES
CCCCCCC
>Mature Secondary Structure 
TPYPEQQDVSAPERILVIEDDKAIRALVTAALESRAMACITAGTGREAIAEASRAGPDV
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCE
ILLDLGLPDMDGTDIIRTVRQWSMVPIIVLSARSEDDDKVAALDAGADDYLTKPFSIDEL
EEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCHHHCCCCCCHHHH
LARLRAALRRGRYERGNPDRDASFFENGPLRIDFAAGSASVNGQEIHLAPMEYKLLCLLA
HHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCEEEECCCCCEEHEEEC
RNAGKVLTHKTILQAVWGSSLPQNLPSLRVFMATLRKKLENAAPRCDYIHTHVGVGYRMA
CCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
RLGETES
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]