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The map label for this gene is nuoC [H]

Identifier: 220904928

GI number: 220904928

Start: 2000298

End: 2000858

Strand: Reverse

Name: nuoC [H]

Synonym: Ddes_1663

Alternate gene names: 220904928

Gene position: 2000858-2000298 (Counterclockwise)

Preceding gene: 220904929

Following gene: 220904927

Centisome position: 69.63

GC content: 62.57

Gene sequence:

>561_bases
ATGGAGTCCCTGGAGATAGCGGACCGCCTGCGCGGGTTTTTTCCTGAAGAAGTGCTGGACGTGCGCGAGTTTCGGGGGCA
GCTGGCGGTTCTGGTGCGGTCCGGCCGCATTCTGGAACTGCTGGCCTACCTGCGCGACGTTCTTGACATGCGGCACCTGC
AAGCCCTGTGTGGCGTGGATAACAGCCGCAGAAACGAACCGGGCCTGAGTCCTTTTGAAGTGGTCTACCATCTTTACTCC
ATCAGGCAGCGCCATGGCATCCGCCTGCGGGCCATGGTGGACGATCCTGAGGAAGGCATTGATTCGGCCGTACCGCTCTG
GACCGGGGCCAACTGGCTGGAGCGGGAAACCTGGGACCTTGTGGGCATACATTTCAGGGGACATCCGGATTTGCGTCGCA
TCCTTCTGCCCGATGACTGGCAGGGGCATCCGCTGCGCAAGGAATATCCCGTGAAAATCCCGGCCCGGGGGCATGAGGAA
TGGGAGGGCCTGACAGCCCTGCGCAAGCGCGCCGCAGAACTGGACGCCCTGAGCTGGCAGGGGGGGGCAAGGCATGAGTA
A

Upstream 100 bases:

>100_bases
TGCCTGTGGATGTTTACGTGCCCGGCTGTCCTCCGCGCCCGGAGGCGCTGTTTGACGGGTTTATCCGGCTTCAGGAGATC
ATCAACAAGGAGCAGATGCG

Downstream 100 bases:

>100_bases
GCAGCGCAAGCAGCATGTGGAGTGCGCCGTGCCCCACGGCCAGCCTACGGGCAGGCTTTCGGCCGAGGAACTGAGCGGTC
TTGAGCAGAGCGATATTGCC

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MESLEIADRLRGFFPEEVLDVREFRGQLAVLVRSGRILELLAYLRDVLDMRHLQALCGVDNSRRNEPGLSPFEVVYHLYS
IRQRHGIRLRAMVDDPEEGIDSAVPLWTGANWLERETWDLVGIHFRGHPDLRRILLPDDWQGHPLRKEYPVKIPARGHEE
WEGLTALRKRAAELDALSWQGGARHE

Sequences:

>Translated_186_residues
MESLEIADRLRGFFPEEVLDVREFRGQLAVLVRSGRILELLAYLRDVLDMRHLQALCGVDNSRRNEPGLSPFEVVYHLYS
IRQRHGIRLRAMVDDPEEGIDSAVPLWTGANWLERETWDLVGIHFRGHPDLRRILLPDDWQGHPLRKEYPVKIPARGHEE
WEGLTALRKRAAELDALSWQGGARHE
>Mature_186_residues
MESLEIADRLRGFFPEEVLDVREFRGQLAVLVRSGRILELLAYLRDVLDMRHLQALCGVDNSRRNEPGLSPFEVVYHLYS
IRQRHGIRLRAMVDDPEEGIDSAVPLWTGANWLERETWDLVGIHFRGHPDLRRILLPDDWQGHPLRKEYPVKIPARGHEE
WEGLTALRKRAAELDALSWQGGARHE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=130, Percent_Identity=38.4615384615385, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI145693162, Length=180, Percent_Identity=35, Blast_Score=94, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32563621, Length=128, Percent_Identity=37.5, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=128, Percent_Identity=37.5, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24656494, Length=142, Percent_Identity=37.3239436619718, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 21599; Mature: 21599

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLEIADRLRGFFPEEVLDVREFRGQLAVLVRSGRILELLAYLRDVLDMRHLQALCGVD
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
NSRRNEPGLSPFEVVYHLYSIRQRHGIRLRAMVDDPEEGIDSAVPLWTGANWLERETWDL
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCCHHHHCCCCE
VGIHFRGHPDLRRILLPDDWQGHPLRKEYPVKIPARGHEEWEGLTALRKRAAELDALSWQ
EEEEECCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
GGARHE
CCCCCC
>Mature Secondary Structure
MESLEIADRLRGFFPEEVLDVREFRGQLAVLVRSGRILELLAYLRDVLDMRHLQALCGVD
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
NSRRNEPGLSPFEVVYHLYSIRQRHGIRLRAMVDDPEEGIDSAVPLWTGANWLERETWDL
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCCHHHHCCCCE
VGIHFRGHPDLRRILLPDDWQGHPLRKEYPVKIPARGHEEWEGLTALRKRAAELDALSWQ
EEEEECCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
GGARHE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA