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The map label for this gene is rpoC [H]

Identifier: 220904902

GI number: 220904902

Start: 1965501

End: 1969670

Strand: Direct

Name: rpoC [H]

Synonym: Ddes_1637

Alternate gene names: 220904902

Gene position: 1965501-1969670 (Clockwise)

Preceding gene: 220904901

Following gene: 220904908

Centisome position: 68.4

GC content: 58.3

Gene sequence:

>4170_bases
ATGAGCCTGGACGATCTTTTCACCGCTCGCGGCACGTCGGCCAACGTGACCAACATCCGCAATCTGAAAGCCATCCAGAT
TTCCATTGCCTCTCCTGAAGCCATCCGCGAATGGTCCTATGGCGAGGTAAAAAAGCCGGAAACCATCAACTACCGTACCT
TCAAGCCTGAGCGCGACGGCCTTTTCTGCGCCAAGATCTTCGGCCCCGTGAAGGACTATGAGTGCAACTGCGGCAAGTAC
AAGCGCATGAAGCACCGCGGCATTGTCTGCGAAAAATGCGGAGTTGAAGTCATTGCGTCCAAGGTGCGTCGCGAGCGCAT
GGGGCACATTGAACTGGCCGCGCCCGTAGCCCACATCTGGTTTTTGAAGACCCTGCCTTCCAAGATCGGCACCCTGCTGG
ACATGACCATGGCCGATCTGGAAAAGGTGCTGTACTTTGACTCTTACATTGTGCTCGACCCGGGCCAGACCAACCTGCAG
AAACGCCAGGTCATTTCCGAAGACCAGTATTTGCAGATTCTGGACCACTACGGCAGCGATGAAGTGCTGACCGTGGGCAT
GGGTGCTGAAGCCGTGCGCAGCCTGCTGGAAGAACTGGAGCTTGAAAAGCTGCGTACCGAACTGCGCGAAGAAGGCGAGG
CCACCAAAAGCCAGACCAAGAAGAAAAAGCTTACCAAGCGTCTCAAGATTGTTGAGGCTTTTCTTGAGTCGGACAACAAG
CCCGAATGGATGATTATGGAAGTTATTCCTGTCATCCCGCCGGAGCTGCGTCCGCTCGTGCCGCTGGACGGCGGGCGTTT
CGCCACCTCCGACCTCAACGATCTGTACCGCCGCGTCATCAACCGTAACAACCGCTTGAAGCGGCTTATGGAGCTTGGCG
CGCCGGAAATCATCATCCGCAACGAAAAGCGCATGCTGCAGGAAGCGGTGGACGCCCTCTTTGACAACGGCCGCCGCGGC
CGCGCCATTGCAGGAACCAACGGCCGTCCCCTCAAGTCCCTTTCGGACATGATCAAGGGCAAGCAGGGCCGTTTCCGCCA
GAACCTGCTGGGCAAGCGCGTGGACTATTCCGGGCGTTCGGTCATTACCGTCGGCCCTTACCTCAAGCTGCACCAGTGCG
GTCTGCCCAAGAAGATGGCGCTTGAACTCTTCAAGCCCTTCATCTATTCGGAGCTGGAAAAACGCGGTCATGCCTCCACT
ATCAAAAGCGCCAAAAAAATGGTGGAGCGCGAAGAGCTGGTTGTCTGGGACATCCTGTCAGAAGTGGTGCGCGAATACCC
TATTCTTCTCAACCGCGCCCCGACCCTGCACCGCCTCGGCATTCAGGCTTTCGAACCGCTGTTGGTCGAAGGCAAGGCCA
TCCGTCTGCACCCGCTGGTCTGCTCCGCATACAACGCGGACTTTGACGGCGACCAGATGGCTGTACATATTCCCCTGTCT
GTAGAAGCGCAGATCGAATGCCGCGTGCTCATGATGAGCACCAACAACATTCTTTCACCCGCCAACGGCGGCCCTGTTAT
CGTGCCTTCGCAGGATATCGTGCTTGGCCTCTACTATATGACGGTGGAACGCAGCTTTGAAAAGGGCGAGGGCATGAGCT
TCTGCGCCCCGTGGGAAGTGGAAAGCGCCTATGACGGCGGCATGGTTTCGCTGCACGCACGCGTCAAGGTGCGCATGCCT
GACGGGCATACCTACGACACCACGCCCGGCCGTGTGCTTGTGAGCGACATTCTCCCGGAAAAGCTGTCCTTTGACCATGT
CAACTGCGTGCTGACCAAGAAGAATATCGCCCGCCTTGTGGGCGCGGCCTACGGCCAGTGCGGCATCAAGGCCACGGTCA
TTCTTTGCGACAAGCTCAAGGATATGGGCTACGAGTTCGCCACCCGCGCCGGTGTGACCATCGGCGTCAAGGACCTGACC
ATTCCCGACCGCAAGAAAGACATTCTTGCCACGTCCCAGGCCGAAGTGGACGACATCGAACACCAGTATCGTGACGGTAT
CATCACCCGTACTGAAAAGTACAACAAGGTGGTGGACGTGTGGACCAAGGCCACGCAGGACGTTTCCACGGAAATGATCA
AGGAAATCTCCTACGATGTGCTCACTGATCCCAAAACCGGCAAGCAGGAAAAGAACCAGAGTTTCAACCCCATCTTCATG
ATGTCCAACTCCGGCGCGCGAGGCAACCAGGACCAGATGCGCCAGCTTGCGGGCATGCGCGGCCTTATGGCCAAGCCTTC
GGGTGAAATTATTGAAACGCCCATCACCTCCTCCTTCCGTGAGGGGCTGTCGGTGTTGCAGTACTTCACCTCCACACACG
GCGCGCGTAAAGGTCTGGCGGACACGGCCCTCAAAACGGCCAACTCCGGTTACCTCACCCGCCGCCTGGTGGACGTGGTG
CAGGATGTCATCGTGGCCGAACACGACTGCGGTACGGTGGACGGCATCGAACTGACCCACCTCAAGGACGGCGGCGATGT
CAAAACGCCCCTGTCTGAACGCATCATCGGCCGCGTACTGCTCTATCCAGTGCATGATCCCGACGCTCCGGAAGAAATCC
TCTTGCCCGAAAACACCATCATTTCGGAAAAAGAGGCCCAGATCATCAGCGACAAGGGCATTTCCTCGGTTACCGTGCGC
TCGCCCCTCACCTGCCAGGCCGAACGGGGCATCTGCGCCTTGTGCTACGGGCGTGACCTTGGCCGCGGGCACCTGGTCAA
TACGGGCGAGACCGTGGGCATCATCGCGGCACAGTCCATCGGTGAGCCCGGCACGCAGCTGACCATGCGTACCTTCCACA
TCGGCGGTACGGCATCCAGCACCATTGAAAAGAACAAGTTTGAAGCCCTCAACGCGGGTCGCGTCATCCTGAACCGGGTC
AAAGCCGTTACCAACAAGGACGGCGTGCACCTGGTGCTGGGCAAGAGCGGCCAGCTGACCATCGTGGACGCTCAGGGCCG
CGAACGCGAAAAGTACATTCTGCCCAACGGCGCACGCCTGCTGGTGCACGATGGGCAGGAAGTGGTCAAGGGTACGGTCA
TGGCCGAATGGGACCCCTTCAACGAACCTTTTGTGTGCGAAGAAGAAGGTACCCTGCGCTTTACCGACATCATTGACGGC
AAGACCGTGCAGGAAAAGGTGGACGACATCACCCGTCAGGCCAGCCTGACAATCATGGAATACCGCACCACCAACTTCCG
CCCGGCCATCTCCATCTGCGATGACAACGGTAACGTGAAAAAGCGCAGCCACGGCGGCGCAGCGGCCATCTATAGCCTGC
CCGTCGGCTCCATCATCATGGTCAAGGACGGCGAGCATATCCAGGCTGGCGACATCATCGCCCGTAAACCCCGCGAAACT
GCAAAAACCAAGGACATCGTGGGCGGTCTGCCCCGCGTGGCCGAGCTTTTTGAGGTGCGCAAGCCCAAAGACATGGCCGT
GGTTTCCGAAATATCGGGTACGGTCACCTATGCGGGCGAATCCAAGGGCAAGCGCAAGCTGGTTGTCACGCCTGAAATCG
GCGAAGCCAAGGAATACCTGGTTCCCAAGGGCAAACACATTACCGCCGCTGACGGCGACTTTGTGGAGGCCGGAGACCCG
TTGACCGAAGGCTACCCCGAACTGCACGACATCCTGCGCACCAAGGGCGAAAAATACCTGGCCCGCTATCTGGTGGACGA
AATTCAGGAAGTCTACCGCTTCCAGGGCGTGGGCATTGACGACAAGCACATTGAAGTCATCGTGCGCCAGATGCTTAAAA
AAGTGACCATTCTGGATACCGGCGGCACCAGCTTCCTGGTGGGCGAACAGGTGGACAAGGGCGAATTCAAGCATGAAAAC
CAGAAGGCTATCGCCGAGGGCCGCCAGCCCGCCACGGCGGAACCTCTGGTGCTGGGCATCACCCAGGCTTCGCTTACCAC
GTCCTCCTTCATCTCGGCGGCTTCCTTCCAGGAAACTACCAAGGTTCTCACCGAGGCCTCCCTCAAGGGCAAGATGGACT
ACCTGCGCGGACTCAAGGAGAACGTCATCGTGGGCCGCCTCATTCCTGCTGGTACAGGCTACCGTGAATACGTCAACGGC
GAGATCATGGTTCCCGACCAGAAGGAACGCCCCGACAAGTTCCTTGAGGAGCTTGAAGAAAACCCTATTCTGGTTGATCT
GAACAGCTAG

Upstream 100 bases:

>100_bases
GGACAAGCGTTGCGTCAGCCGTCAGCGGCATGCCCGCTCACGGCTGACGACAGCATAGCTAACGATTCCAACGAGCTTTT
ACCAAAGCAAGGTATTATAT

Downstream 100 bases:

>100_bases
AGCAATTAACGCTTCAAATGATTGTAGGGCGGCTTTGCCGCCCTACAATCATTTGGAGACAAATCTTTCCAGAGCATTTC
AAGTATGAAATGCTCTGGAA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1389; Mature: 1388

Protein sequence:

>1389_residues
MSLDDLFTARGTSANVTNIRNLKAIQISIASPEAIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKY
KRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGQTNLQ
KRQVISEDQYLQILDHYGSDEVLTVGMGAEAVRSLLEELELEKLRTELREEGEATKSQTKKKKLTKRLKIVEAFLESDNK
PEWMIMEVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPEIIIRNEKRMLQEAVDALFDNGRRG
RAIAGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLKLHQCGLPKKMALELFKPFIYSELEKRGHAST
IKSAKKMVEREELVVWDILSEVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIRLHPLVCSAYNADFDGDQMAVHIPLS
VEAQIECRVLMMSTNNILSPANGGPVIVPSQDIVLGLYYMTVERSFEKGEGMSFCAPWEVESAYDGGMVSLHARVKVRMP
DGHTYDTTPGRVLVSDILPEKLSFDHVNCVLTKKNIARLVGAAYGQCGIKATVILCDKLKDMGYEFATRAGVTIGVKDLT
IPDRKKDILATSQAEVDDIEHQYRDGIITRTEKYNKVVDVWTKATQDVSTEMIKEISYDVLTDPKTGKQEKNQSFNPIFM
MSNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSSFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVV
QDVIVAEHDCGTVDGIELTHLKDGGDVKTPLSERIIGRVLLYPVHDPDAPEEILLPENTIISEKEAQIISDKGISSVTVR
SPLTCQAERGICALCYGRDLGRGHLVNTGETVGIIAAQSIGEPGTQLTMRTFHIGGTASSTIEKNKFEALNAGRVILNRV
KAVTNKDGVHLVLGKSGQLTIVDAQGREREKYILPNGARLLVHDGQEVVKGTVMAEWDPFNEPFVCEEEGTLRFTDIIDG
KTVQEKVDDITRQASLTIMEYRTTNFRPAISICDDNGNVKKRSHGGAAAIYSLPVGSIIMVKDGEHIQAGDIIARKPRET
AKTKDIVGGLPRVAELFEVRKPKDMAVVSEISGTVTYAGESKGKRKLVVTPEIGEAKEYLVPKGKHITAADGDFVEAGDP
LTEGYPELHDILRTKGEKYLARYLVDEIQEVYRFQGVGIDDKHIEVIVRQMLKKVTILDTGGTSFLVGEQVDKGEFKHEN
QKAIAEGRQPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLKGKMDYLRGLKENVIVGRLIPAGTGYREYVNG
EIMVPDQKERPDKFLEELEENPILVDLNS

Sequences:

>Translated_1389_residues
MSLDDLFTARGTSANVTNIRNLKAIQISIASPEAIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKY
KRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGQTNLQ
KRQVISEDQYLQILDHYGSDEVLTVGMGAEAVRSLLEELELEKLRTELREEGEATKSQTKKKKLTKRLKIVEAFLESDNK
PEWMIMEVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPEIIIRNEKRMLQEAVDALFDNGRRG
RAIAGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLKLHQCGLPKKMALELFKPFIYSELEKRGHAST
IKSAKKMVEREELVVWDILSEVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIRLHPLVCSAYNADFDGDQMAVHIPLS
VEAQIECRVLMMSTNNILSPANGGPVIVPSQDIVLGLYYMTVERSFEKGEGMSFCAPWEVESAYDGGMVSLHARVKVRMP
DGHTYDTTPGRVLVSDILPEKLSFDHVNCVLTKKNIARLVGAAYGQCGIKATVILCDKLKDMGYEFATRAGVTIGVKDLT
IPDRKKDILATSQAEVDDIEHQYRDGIITRTEKYNKVVDVWTKATQDVSTEMIKEISYDVLTDPKTGKQEKNQSFNPIFM
MSNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSSFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVV
QDVIVAEHDCGTVDGIELTHLKDGGDVKTPLSERIIGRVLLYPVHDPDAPEEILLPENTIISEKEAQIISDKGISSVTVR
SPLTCQAERGICALCYGRDLGRGHLVNTGETVGIIAAQSIGEPGTQLTMRTFHIGGTASSTIEKNKFEALNAGRVILNRV
KAVTNKDGVHLVLGKSGQLTIVDAQGREREKYILPNGARLLVHDGQEVVKGTVMAEWDPFNEPFVCEEEGTLRFTDIIDG
KTVQEKVDDITRQASLTIMEYRTTNFRPAISICDDNGNVKKRSHGGAAAIYSLPVGSIIMVKDGEHIQAGDIIARKPRET
AKTKDIVGGLPRVAELFEVRKPKDMAVVSEISGTVTYAGESKGKRKLVVTPEIGEAKEYLVPKGKHITAADGDFVEAGDP
LTEGYPELHDILRTKGEKYLARYLVDEIQEVYRFQGVGIDDKHIEVIVRQMLKKVTILDTGGTSFLVGEQVDKGEFKHEN
QKAIAEGRQPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLKGKMDYLRGLKENVIVGRLIPAGTGYREYVNG
EIMVPDQKERPDKFLEELEENPILVDLNS
>Mature_1388_residues
SLDDLFTARGTSANVTNIRNLKAIQISIASPEAIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKYK
RMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGQTNLQK
RQVISEDQYLQILDHYGSDEVLTVGMGAEAVRSLLEELELEKLRTELREEGEATKSQTKKKKLTKRLKIVEAFLESDNKP
EWMIMEVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPEIIIRNEKRMLQEAVDALFDNGRRGR
AIAGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLKLHQCGLPKKMALELFKPFIYSELEKRGHASTI
KSAKKMVEREELVVWDILSEVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIRLHPLVCSAYNADFDGDQMAVHIPLSV
EAQIECRVLMMSTNNILSPANGGPVIVPSQDIVLGLYYMTVERSFEKGEGMSFCAPWEVESAYDGGMVSLHARVKVRMPD
GHTYDTTPGRVLVSDILPEKLSFDHVNCVLTKKNIARLVGAAYGQCGIKATVILCDKLKDMGYEFATRAGVTIGVKDLTI
PDRKKDILATSQAEVDDIEHQYRDGIITRTEKYNKVVDVWTKATQDVSTEMIKEISYDVLTDPKTGKQEKNQSFNPIFMM
SNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSSFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVVQ
DVIVAEHDCGTVDGIELTHLKDGGDVKTPLSERIIGRVLLYPVHDPDAPEEILLPENTIISEKEAQIISDKGISSVTVRS
PLTCQAERGICALCYGRDLGRGHLVNTGETVGIIAAQSIGEPGTQLTMRTFHIGGTASSTIEKNKFEALNAGRVILNRVK
AVTNKDGVHLVLGKSGQLTIVDAQGREREKYILPNGARLLVHDGQEVVKGTVMAEWDPFNEPFVCEEEGTLRFTDIIDGK
TVQEKVDDITRQASLTIMEYRTTNFRPAISICDDNGNVKKRSHGGAAAIYSLPVGSIIMVKDGEHIQAGDIIARKPRETA
KTKDIVGGLPRVAELFEVRKPKDMAVVSEISGTVTYAGESKGKRKLVVTPEIGEAKEYLVPKGKHITAADGDFVEAGDPL
TEGYPELHDILRTKGEKYLARYLVDEIQEVYRFQGVGIDDKHIEVIVRQMLKKVTILDTGGTSFLVGEQVDKGEFKHENQ
KAIAEGRQPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLKGKMDYLRGLKENVIVGRLIPAGTGYREYVNGE
IMVPDQKERPDKFLEELEENPILVDLNS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=941, Percent_Identity=26.0361317747078, Blast_Score=208, Evalue=3e-53,
Organism=Homo sapiens, GI39725938, Length=348, Percent_Identity=28.448275862069, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI103471997, Length=656, Percent_Identity=24.0853658536585, Blast_Score=125, Evalue=3e-28,
Organism=Escherichia coli, GI2367335, Length=1356, Percent_Identity=59.1445427728613, Blast_Score=1662, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=929, Percent_Identity=25.4036598493003, Blast_Score=179, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI25145495, Length=867, Percent_Identity=25.0288350634371, Blast_Score=177, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6320061, Length=914, Percent_Identity=24.72647702407, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6324690, Length=320, Percent_Identity=29.6875, Blast_Score=133, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324917, Length=656, Percent_Identity=24.2378048780488, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281360912, Length=688, Percent_Identity=27.0348837209302, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI17530899, Length=569, Percent_Identity=28.1195079086116, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI17647875, Length=346, Percent_Identity=26.5895953757225, Blast_Score=104, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 154296; Mature: 154164

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDDLFTARGTSANVTNIRNLKAIQISIASPEAIREWSYGEVKKPETINYRTFKPERDG
CCCHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCC
LFCAKIFGPVKDYECNCGKYKRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIW
EEEEHHHCCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHH
FLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGQTNLQKRQVISEDQYLQILDHYGSD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCHHHHHHHHHCCCC
EVLTVGMGAEAVRSLLEELELEKLRTELREEGEATKSQTKKKKLTKRLKIVEAFLESDNK
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEWMIMEVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPEIIIR
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEE
NEKRMLQEAVDALFDNGRRGRAIAGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRS
CHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCE
VITVGPYLKLHQCGLPKKMALELFKPFIYSELEKRGHASTIKSAKKMVEREELVVWDILS
EEEECCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIRLHPLVCSAYNADFDGDQMAVHIPLS
HHHHHCCHHHCCCCCHHHHCHHHHCHHHCCCCEEEEEEEEEEECCCCCCCCEEEEEEEEE
VEAQIECRVLMMSTNNILSPANGGPVIVPSQDIVLGLYYMTVERSFEKGEGMSFCAPWEV
EEEEEEEEEEEEECCCEECCCCCCCEEECCCCCEEEEHHHHHHHHHCCCCCCCEECCCCC
ESAYDGGMVSLHARVKVRMPDGHTYDTTPGRVLVSDILPEKLSFDHVNCVLTKKNIARLV
CCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEHHHHCCCCCCCCCEEEEEEHHHHHHHH
GAAYGQCGIKATVILCDKLKDMGYEFATRAGVTIGVKDLTIPDRKKDILATSQAEVDDIE
HHHHCCCCCEEEEEEEHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHH
HQYRDGIITRTEKYNKVVDVWTKATQDVSTEMIKEISYDVLTDPKTGKQEKNQSFNPIFM
HHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHCCCCCCEEEE
MSNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSSFREGLSVLQYFTSTHGARKGLA
EECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHCCHH
DTALKTANSGYLTRRLVDVVQDVIVAEHDCGTVDGIELTHLKDGGDVKTPLSERIIGRVL
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCEEE
LYPVHDPDAPEEILLPENTIISEKEAQIISDKGISSVTVRSPLTCQAERGICALCYGRDL
EEECCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCEEEECCCCEEECCCCEEEEEECCCC
GRGHLVNTGETVGIIAAQSIGEPGTQLTMRTFHIGGTASSTIEKNKFEALNAGRVILNRV
CCCCEECCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHH
KAVTNKDGVHLVLGKSGQLTIVDAQGREREKYILPNGARLLVHDGQEVVKGTVMAEWDPF
HHHCCCCCEEEEECCCCCEEEEECCCCCCCEEECCCCCEEEEECCHHHHCCEEEEECCCC
NEPFVCEEEGTLRFTDIIDGKTVQEKVDDITRQASLTIMEYRTTNFRPAISICDDNGNVK
CCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEECCCCCEE
KRSHGGAAAIYSLPVGSIIMVKDGEHIQAGDIIARKPRETAKTKDIVGGLPRVAELFEVR
ECCCCCEEEEEECCCCEEEEEECCCEEECCCEEECCCHHHHHHHHHHCCCHHHHHHHHHC
KPKDMAVVSEISGTVTYAGESKGKRKLVVTPEIGEAKEYLVPKGKHITAADGDFVEAGDP
CCCCHHHHHHCCCEEEECCCCCCCEEEEECCCCCCCHHHHCCCCCEEEECCCCCCCCCCC
LTEGYPELHDILRTKGEKYLARYLVDEIQEVYRFQGVGIDDKHIEVIVRQMLKKVTILDT
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEC
GGTSFLVGEQVDKGEFKHENQKAIAEGRQPATAEPLVLGITQASLTTSSFISAASFQETT
CCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
KVLTEASLKGKMDYLRGLKENVIVGRLIPAGTGYREYVNGEIMVPDQKERPDKFLEELEE
HHHHHHHHHCHHHHHHCCHHCEEEEEEECCCCCHHHHCCCEEECCCCCCCHHHHHHHHCC
NPILVDLNS
CCEEEEECC
>Mature Secondary Structure 
SLDDLFTARGTSANVTNIRNLKAIQISIASPEAIREWSYGEVKKPETINYRTFKPERDG
CCHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCC
LFCAKIFGPVKDYECNCGKYKRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIW
EEEEHHHCCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCEEEHHHHHHHH
FLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGQTNLQKRQVISEDQYLQILDHYGSD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCHHHHHHHHHCCCC
EVLTVGMGAEAVRSLLEELELEKLRTELREEGEATKSQTKKKKLTKRLKIVEAFLESDNK
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEWMIMEVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPEIIIR
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEE
NEKRMLQEAVDALFDNGRRGRAIAGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRS
CHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCE
VITVGPYLKLHQCGLPKKMALELFKPFIYSELEKRGHASTIKSAKKMVEREELVVWDILS
EEEECCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIRLHPLVCSAYNADFDGDQMAVHIPLS
HHHHHCCHHHCCCCCHHHHCHHHHCHHHCCCCEEEEEEEEEEECCCCCCCCEEEEEEEEE
VEAQIECRVLMMSTNNILSPANGGPVIVPSQDIVLGLYYMTVERSFEKGEGMSFCAPWEV
EEEEEEEEEEEEECCCEECCCCCCCEEECCCCCEEEEHHHHHHHHHCCCCCCCEECCCCC
ESAYDGGMVSLHARVKVRMPDGHTYDTTPGRVLVSDILPEKLSFDHVNCVLTKKNIARLV
CCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEHHHHCCCCCCCCCEEEEEEHHHHHHHH
GAAYGQCGIKATVILCDKLKDMGYEFATRAGVTIGVKDLTIPDRKKDILATSQAEVDDIE
HHHHCCCCCEEEEEEEHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHH
HQYRDGIITRTEKYNKVVDVWTKATQDVSTEMIKEISYDVLTDPKTGKQEKNQSFNPIFM
HHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHCCCCCCEEEE
MSNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSSFREGLSVLQYFTSTHGARKGLA
EECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHCCHH
DTALKTANSGYLTRRLVDVVQDVIVAEHDCGTVDGIELTHLKDGGDVKTPLSERIIGRVL
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCEEE
LYPVHDPDAPEEILLPENTIISEKEAQIISDKGISSVTVRSPLTCQAERGICALCYGRDL
EEECCCCCCCCCEECCCCCCCCCHHHHHHHCCCCCEEEECCCCEEECCCCEEEEEECCCC
GRGHLVNTGETVGIIAAQSIGEPGTQLTMRTFHIGGTASSTIEKNKFEALNAGRVILNRV
CCCCEECCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCHHHHHHHH
KAVTNKDGVHLVLGKSGQLTIVDAQGREREKYILPNGARLLVHDGQEVVKGTVMAEWDPF
HHHCCCCCEEEEECCCCCEEEEECCCCCCCEEECCCCCEEEEECCHHHHCCEEEEECCCC
NEPFVCEEEGTLRFTDIIDGKTVQEKVDDITRQASLTIMEYRTTNFRPAISICDDNGNVK
CCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEECCCCCEE
KRSHGGAAAIYSLPVGSIIMVKDGEHIQAGDIIARKPRETAKTKDIVGGLPRVAELFEVR
ECCCCCEEEEEECCCCEEEEEECCCEEECCCEEECCCHHHHHHHHHHCCCHHHHHHHHHC
KPKDMAVVSEISGTVTYAGESKGKRKLVVTPEIGEAKEYLVPKGKHITAADGDFVEAGDP
CCCCHHHHHHCCCEEEECCCCCCCEEEEECCCCCCCHHHHCCCCCEEEECCCCCCCCCCC
LTEGYPELHDILRTKGEKYLARYLVDEIQEVYRFQGVGIDDKHIEVIVRQMLKKVTILDT
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEC
GGTSFLVGEQVDKGEFKHENQKAIAEGRQPATAEPLVLGITQASLTTSSFISAASFQETT
CCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
KVLTEASLKGKMDYLRGLKENVIVGRLIPAGTGYREYVNGEIMVPDQKERPDKFLEELEE
HHHHHHHHHCHHHHHHCCHHCEEEEEEECCCCCHHHHCCCEEECCCCCCCHHHHHHHHCC
NPILVDLNS
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA