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The map label for this gene is rpoB

Identifier: 220904901

GI number: 220904901

Start: 1961243

End: 1965379

Strand: Direct

Name: rpoB

Synonym: Ddes_1636

Alternate gene names: 220904901

Gene position: 1961243-1965379 (Clockwise)

Preceding gene: 220904900

Following gene: 220904902

Centisome position: 68.25

GC content: 58.01

Gene sequence:

>4137_bases
ATGGGCCAGCTCACCAAACAGTTCGGCAAGATCAAGATCTCCCTCCCTATCCCCCATCTGCTAAATCTGCAGATAGACTC
ATATGAAAAGTTTCTTCAGGAAGGTGTTCCAGAAGCCGAACGCCGCCCTGACGAAGGACTTGAGGGCGTTTTTCATACGG
TCTTTCCTATTGAAGACTTTAACAAAACCGCCAGTCTGGAATTTGTCAGCTATGAAATAGGCGAGCCAAAATACGACCAG
GCCGAATGTATTTCAAAAGGCCTGACGTACGAAGCCCCCATGCGCATTAAAGTGCGCCTTGTGGTGTATGATGCCGACGA
AGCTTCGGGCAACCGGACTATTCGCGACATCAAGGAGCAGGATATCTATTTCGGTACCCTGCCCCTCATGACCGAAAAGG
GCACCTTTATCATAAACGGCACTGAACGCGTCATCGTCAACCAGTTGCAGCGTTCGCCCGGCATCATTTTCGAGCACGAC
GGCGGCAAGACGCATACCAGCCGCAAGGTGCTCTATTCGTGCCGGGTCATCCCCATGCGCGGCTCCTGGCTGGACTTCGA
CTTTGACCACAAGGACATTCTCTACGTCCGCATCGACCGCCGCCGCAAAATGCCCGCCACCATCCTGTTCAAGGCGATGG
GCATGAGCAAGGAACAGATCCTTGACTACTTCTATACGCAGGAAACCTACCGTCTGGAAGAACGCAACACCATTTTCTGG
GAAGTGCGCAAGGAACTGTACCGCAAGGACAACGCCTATGCCGACATCGTCGACAGCGAAGGCAATGTCATCGTCAAGGC
CGGCAAGCCCATTACCAAACGCAGCTGGCGTCTTATCTGCGAGGCGGGCATCGAAGCCATCGAAATGCGCCCCGATACCC
TGGACGGCATGTTCCTGGCCGGAGACGTGGCGGATCCCAAGACTGGCGAACTGCTGGCCGAGGCTGCGGACGAAATCACT
CCCGGGCTGCTGGACCGCATGCGTGATGCGGGCATCAACCGCGTGAGCGTGCTGCATACCAAGGGCAACGACACCTCTTC
CTCCATCCGAGACACCCTCATGCTGGACCGCATTCCGGACCAGCTGAAGGCGCAGGAGGAAATATACCGTCGCCTGCGTC
CCTCTTCGCCGCCCACGGCGGAAATTGCGGCCAGTTTCTTTGACAACCTGTTCCGCAATCCCGACTACTACGATCTGTCG
CCCGTGGGTCGGTACAAGCTCAACCAGCGCCTCAGCCTGGACGAGCCTTCCGATCTGCGCACCCTGACGGACAACGACAT
TCTTACGGCCATCAAGGTGCTGGTCCACCTCAAGGACAGCCACGGCCCTGCTGACGATATCGACCATCTCGGCAACCGTC
GCGTGCGTCTGGTAGGCGAACTTGTGGAAAACCAGTATCGTATCGGCCTTGTCCGTATGGAGCGCGCCATCAAGGAGCGC
ATGAGCCTGCAGGAAATCTCCACACTCATGCCGCACGACCTTATCAACCCCAAGCCTGTGGCTGCCGTGTTGAAGGAATT
CTTCGGCACATCGCAGTTGTCGCAGTTTATGGACCAGACCAACTCCCTTTCCGAAGTGACGCACAAGCGCCGCCTCTCGG
CCCTGGGACCCGGCGGCCTGACCCGTGAACGCGCAGGTTTTGAGGTGCGCGACGTGCATACCTCGCACTATGGCCGCATC
TGCCCCATTGAAACGCCCGAAGGTCCCAACATCGGCCTTATCGTTTCGCTGACCACCTTTGCCAAGGTCAATGACTACGG
CTTCATTGAAACGCCCTATCATGTGGTGCGTGAAGGCCGGGTCACCGATGAAGTGCTCCACCTCGACGCCTCCCGCGAAG
GGGATCAGGTGGTGGCGCAGGCCAACGCACTGCTGGACGAGCAGGGCAACCTTGTGGACGAATTCGTCACCGTGCGCGTC
AAGGGCGAAGTGGAAATGCGCCATCGCGACGAAGTGACCCTTATGGACATTTCGCCCAGCCAGATGGTTTCCATCTCGGC
CGCGCTTATCCCCTTCCTGGAGCATGACGACGCCAACCGCGCGCTCATGGGTTCCAACATGCAGCGTCAGGCCGTGCCCC
TGCTCCGGTCCGAGAAACCCCTTGTGGGAACCGGCATGGAAGTGGACGTGGCCCGCGACTCCGGTGCATGCATAGTTGCT
CCGGCTGACGGCAAGATCGAATACGTGGATGCGGACCGCATCGTGGTGGCCTACGAGGGCGATGTGTACAAAAAGCAGGG
CGGCGTACGCGCTTACGACCTGCTCAAGTACCACAAGTCCAACCAGAACTCCTGCTTTGGACAGAAGCCCAGCTGCCACC
CCGGCCAGATTGTTAAAAAAGGCCAGATTCTGGCTGACGGCCCCGGCATTGACGATGGCGAACTGGCCCTCGGCAAGAAC
CTGGTGGTGGCCTTCATGCCCTGGTGCGGCTACAACTATGAAGACTCCATCCTCATCTCTGAACGTACGGTGAAGGAAGA
CGTCTTCACGTCCATCCACATTGAGGAATTCGAGGTGGTGGCCCGCGATACCAAGCTGGGACCCGAAGAAATCACCCGCG
ATATTCCCAACGTCAGCGAAGATATGCTGCGTAACCTGGATGAAAGCGGCATTATCCGCATCGGCGCGGCAGTCAAGCCC
GACGACATCCTGGTAGGTAAAATTACCCCAAAGGGCGAAACCCAGCTTACCCCCGAAGAAAAGCTCCTGAGGGCCATCTT
CGGCGAAAAGGCCAGGGATGTAAAAAACACGTCCCTCAAGGTTCCCCCGGGAGTGGAAGGCACCATTATTGACGTCAAGG
TCTTCAACCGCCGTTCCGGCGAAAAGGACGACCGCACCCTGGCCATTGAAGGCCACGACACCGCAGTGCTCGACCAGAAA
GAAGCCGATCACATGCGCGCCCTTACGGACCGTACCCGCGCCCTGCTGATCCCGCACGTGGTAGGTAAGCAGGTGGCCGC
ATCCCTGCCCGGTAAAAAGAAGGGTGAAGTGCTGGTGGAAGCCGGCGCGGCCCTGACGGAAGAAATGCTGGCCAGCCTGC
CGGTGAAGAAGCTTTCCGGCCTCTTCAAGAGCAAGGAAGTCAACGATGCCGTGGCCGAAATCCTCAAGCCCTATGACCAG
CAGGTCGACTACCTGCACGCCATTTACGATTCCAAGCGCGAAAAGGTCACTGAAGGCGATGATCTGCCCCCCGGCGTCAT
CAAGATGGTCAAGGTGCATATCGCCATCAAGCGCAAGCTTTCTGTGGGTGACAAAATGGCCGGCCGCCACGGCAACAAGG
GTGTTGTTTCCTGCATTCTGCCGGAAGAAGACATGCCTTTCTTTGCCGACGGCCGCCCCGTGGATATCGTGCTCAACCCC
CTGGGCGTGCCCTCGCGTATGAACATCGGCCAGATCATGGAAACCCACCTCGGCTGGGGAGCCAAGGAACTGGGCCGTCA
GCTGGCGGAACTTCTGGATTCCGGCGCGGCCATGCAGGTGCTGCGTGATGAAGTGAAGAGCATCTTCAGCTCTGACGACA
TCAACGCCCTGGTGGACGAGATGGATGATGAAGAGTTCAAGGCCTCTGTGAGCAAGCTGCGCAACGGCATCGTGACCAAA
ACGCCTGTTTTTGACGGCGCGACCGAAGAAGAAATATGGAGCTGGATGGAAAGAGCCGGCCTTGCCAATGACGGCAAGAC
AACTCTTTACGACGGGCGCACGGGCGAAGCCTTCAAAAACCGCGTGACCACGGGTGTCATGTACATGCTCAAACTGCACC
ACCTGGTGGACGAAAAAATCCACGCCCGCTCCACGGGCCCCTACTCCCTGGTGACGCAGCAGCCCCTGGGCGGCAAGGCC
CAGTTCGGCGGCCAGCGCCTGGGTGAAATGGAAGTGTGGGCGCTTGAAGCTTACGGCGCCGCCTACCTGCTGCAGGAGTT
CCTCACGGTCAAGTCCGACGACGTGACCGGGCGCGTGAAAATGTATGAAAAAATAGTCAAGGGTGACAACTTCCTTGAAG
CCGGTCTGCCCGAATCCTTCAACGTTCTGGTCAAGGAGCTCATGAGCCTTGGGCTTAACGTGACCCTGCACCAGGAAGAA
GGTAAGAAAAAGCCCAAGCGTACGGGCTATATGAGAGAACGCGAGGACGAGGCTTAA

Upstream 100 bases:

>100_bases
TTTCAGGGTGCAGTGACAGCAAGTTTTTTGCCCGCCGGCTTCGGCAGATACTTCTTTGTCGCTCCGCCGGGGCGCAACCG
CTACCTATCTTGAGGTACCC

Downstream 100 bases:

>100_bases
ACCGCCCCATTCGGCGGGCACGGACAAGCGTTGCGTCAGCCGTCAGCGGCATGCCCGCTCACGGCTGACGACAGCATAGC
TAACGATTCCAACGAGCTTT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1378; Mature: 1377

Protein sequence:

>1378_residues
MGQLTKQFGKIKISLPIPHLLNLQIDSYEKFLQEGVPEAERRPDEGLEGVFHTVFPIEDFNKTASLEFVSYEIGEPKYDQ
AECISKGLTYEAPMRIKVRLVVYDADEASGNRTIRDIKEQDIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHD
GGKTHTSRKVLYSCRVIPMRGSWLDFDFDHKDILYVRIDRRRKMPATILFKAMGMSKEQILDYFYTQETYRLEERNTIFW
EVRKELYRKDNAYADIVDSEGNVIVKAGKPITKRSWRLICEAGIEAIEMRPDTLDGMFLAGDVADPKTGELLAEAADEIT
PGLLDRMRDAGINRVSVLHTKGNDTSSSIRDTLMLDRIPDQLKAQEEIYRRLRPSSPPTAEIAASFFDNLFRNPDYYDLS
PVGRYKLNQRLSLDEPSDLRTLTDNDILTAIKVLVHLKDSHGPADDIDHLGNRRVRLVGELVENQYRIGLVRMERAIKER
MSLQEISTLMPHDLINPKPVAAVLKEFFGTSQLSQFMDQTNSLSEVTHKRRLSALGPGGLTRERAGFEVRDVHTSHYGRI
CPIETPEGPNIGLIVSLTTFAKVNDYGFIETPYHVVREGRVTDEVLHLDASREGDQVVAQANALLDEQGNLVDEFVTVRV
KGEVEMRHRDEVTLMDISPSQMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSEKPLVGTGMEVDVARDSGACIVA
PADGKIEYVDADRIVVAYEGDVYKKQGGVRAYDLLKYHKSNQNSCFGQKPSCHPGQIVKKGQILADGPGIDDGELALGKN
LVVAFMPWCGYNYEDSILISERTVKEDVFTSIHIEEFEVVARDTKLGPEEITRDIPNVSEDMLRNLDESGIIRIGAAVKP
DDILVGKITPKGETQLTPEEKLLRAIFGEKARDVKNTSLKVPPGVEGTIIDVKVFNRRSGEKDDRTLAIEGHDTAVLDQK
EADHMRALTDRTRALLIPHVVGKQVAASLPGKKKGEVLVEAGAALTEEMLASLPVKKLSGLFKSKEVNDAVAEILKPYDQ
QVDYLHAIYDSKREKVTEGDDLPPGVIKMVKVHIAIKRKLSVGDKMAGRHGNKGVVSCILPEEDMPFFADGRPVDIVLNP
LGVPSRMNIGQIMETHLGWGAKELGRQLAELLDSGAAMQVLRDEVKSIFSSDDINALVDEMDDEEFKASVSKLRNGIVTK
TPVFDGATEEEIWSWMERAGLANDGKTTLYDGRTGEAFKNRVTTGVMYMLKLHHLVDEKIHARSTGPYSLVTQQPLGGKA
QFGGQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYEKIVKGDNFLEAGLPESFNVLVKELMSLGLNVTLHQEE
GKKKPKRTGYMREREDEA

Sequences:

>Translated_1378_residues
MGQLTKQFGKIKISLPIPHLLNLQIDSYEKFLQEGVPEAERRPDEGLEGVFHTVFPIEDFNKTASLEFVSYEIGEPKYDQ
AECISKGLTYEAPMRIKVRLVVYDADEASGNRTIRDIKEQDIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHD
GGKTHTSRKVLYSCRVIPMRGSWLDFDFDHKDILYVRIDRRRKMPATILFKAMGMSKEQILDYFYTQETYRLEERNTIFW
EVRKELYRKDNAYADIVDSEGNVIVKAGKPITKRSWRLICEAGIEAIEMRPDTLDGMFLAGDVADPKTGELLAEAADEIT
PGLLDRMRDAGINRVSVLHTKGNDTSSSIRDTLMLDRIPDQLKAQEEIYRRLRPSSPPTAEIAASFFDNLFRNPDYYDLS
PVGRYKLNQRLSLDEPSDLRTLTDNDILTAIKVLVHLKDSHGPADDIDHLGNRRVRLVGELVENQYRIGLVRMERAIKER
MSLQEISTLMPHDLINPKPVAAVLKEFFGTSQLSQFMDQTNSLSEVTHKRRLSALGPGGLTRERAGFEVRDVHTSHYGRI
CPIETPEGPNIGLIVSLTTFAKVNDYGFIETPYHVVREGRVTDEVLHLDASREGDQVVAQANALLDEQGNLVDEFVTVRV
KGEVEMRHRDEVTLMDISPSQMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSEKPLVGTGMEVDVARDSGACIVA
PADGKIEYVDADRIVVAYEGDVYKKQGGVRAYDLLKYHKSNQNSCFGQKPSCHPGQIVKKGQILADGPGIDDGELALGKN
LVVAFMPWCGYNYEDSILISERTVKEDVFTSIHIEEFEVVARDTKLGPEEITRDIPNVSEDMLRNLDESGIIRIGAAVKP
DDILVGKITPKGETQLTPEEKLLRAIFGEKARDVKNTSLKVPPGVEGTIIDVKVFNRRSGEKDDRTLAIEGHDTAVLDQK
EADHMRALTDRTRALLIPHVVGKQVAASLPGKKKGEVLVEAGAALTEEMLASLPVKKLSGLFKSKEVNDAVAEILKPYDQ
QVDYLHAIYDSKREKVTEGDDLPPGVIKMVKVHIAIKRKLSVGDKMAGRHGNKGVVSCILPEEDMPFFADGRPVDIVLNP
LGVPSRMNIGQIMETHLGWGAKELGRQLAELLDSGAAMQVLRDEVKSIFSSDDINALVDEMDDEEFKASVSKLRNGIVTK
TPVFDGATEEEIWSWMERAGLANDGKTTLYDGRTGEAFKNRVTTGVMYMLKLHHLVDEKIHARSTGPYSLVTQQPLGGKA
QFGGQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYEKIVKGDNFLEAGLPESFNVLVKELMSLGLNVTLHQEE
GKKKPKRTGYMREREDEA
>Mature_1377_residues
GQLTKQFGKIKISLPIPHLLNLQIDSYEKFLQEGVPEAERRPDEGLEGVFHTVFPIEDFNKTASLEFVSYEIGEPKYDQA
ECISKGLTYEAPMRIKVRLVVYDADEASGNRTIRDIKEQDIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDG
GKTHTSRKVLYSCRVIPMRGSWLDFDFDHKDILYVRIDRRRKMPATILFKAMGMSKEQILDYFYTQETYRLEERNTIFWE
VRKELYRKDNAYADIVDSEGNVIVKAGKPITKRSWRLICEAGIEAIEMRPDTLDGMFLAGDVADPKTGELLAEAADEITP
GLLDRMRDAGINRVSVLHTKGNDTSSSIRDTLMLDRIPDQLKAQEEIYRRLRPSSPPTAEIAASFFDNLFRNPDYYDLSP
VGRYKLNQRLSLDEPSDLRTLTDNDILTAIKVLVHLKDSHGPADDIDHLGNRRVRLVGELVENQYRIGLVRMERAIKERM
SLQEISTLMPHDLINPKPVAAVLKEFFGTSQLSQFMDQTNSLSEVTHKRRLSALGPGGLTRERAGFEVRDVHTSHYGRIC
PIETPEGPNIGLIVSLTTFAKVNDYGFIETPYHVVREGRVTDEVLHLDASREGDQVVAQANALLDEQGNLVDEFVTVRVK
GEVEMRHRDEVTLMDISPSQMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSEKPLVGTGMEVDVARDSGACIVAP
ADGKIEYVDADRIVVAYEGDVYKKQGGVRAYDLLKYHKSNQNSCFGQKPSCHPGQIVKKGQILADGPGIDDGELALGKNL
VVAFMPWCGYNYEDSILISERTVKEDVFTSIHIEEFEVVARDTKLGPEEITRDIPNVSEDMLRNLDESGIIRIGAAVKPD
DILVGKITPKGETQLTPEEKLLRAIFGEKARDVKNTSLKVPPGVEGTIIDVKVFNRRSGEKDDRTLAIEGHDTAVLDQKE
ADHMRALTDRTRALLIPHVVGKQVAASLPGKKKGEVLVEAGAALTEEMLASLPVKKLSGLFKSKEVNDAVAEILKPYDQQ
VDYLHAIYDSKREKVTEGDDLPPGVIKMVKVHIAIKRKLSVGDKMAGRHGNKGVVSCILPEEDMPFFADGRPVDIVLNPL
GVPSRMNIGQIMETHLGWGAKELGRQLAELLDSGAAMQVLRDEVKSIFSSDDINALVDEMDDEEFKASVSKLRNGIVTKT
PVFDGATEEEIWSWMERAGLANDGKTTLYDGRTGEAFKNRVTTGVMYMLKLHHLVDEKIHARSTGPYSLVTQQPLGGKAQ
FGGQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVKMYEKIVKGDNFLEAGLPESFNVLVKELMSLGLNVTLHQEEG
KKKPKRTGYMREREDEA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=294, Percent_Identity=29.9319727891156, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI238908503, Length=294, Percent_Identity=29.9319727891156, Blast_Score=125, Evalue=4e-28,
Organism=Homo sapiens, GI33469941, Length=276, Percent_Identity=32.9710144927536, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI212286172, Length=276, Percent_Identity=32.9710144927536, Blast_Score=124, Evalue=7e-28,
Organism=Homo sapiens, GI4505941, Length=246, Percent_Identity=30.0813008130081, Blast_Score=120, Evalue=1e-26,
Organism=Escherichia coli, GI1790419, Length=1365, Percent_Identity=53.992673992674, Blast_Score=1442, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=294, Percent_Identity=30.6122448979592, Blast_Score=123, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17552304, Length=246, Percent_Identity=30.0813008130081, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=238, Percent_Identity=29.8319327731092, Blast_Score=113, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=302, Percent_Identity=30.4635761589404, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6325267, Length=247, Percent_Identity=32.7935222672065, Blast_Score=127, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6324725, Length=313, Percent_Identity=28.7539936102236, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17647877, Length=294, Percent_Identity=30.2721088435374, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17136444, Length=301, Percent_Identity=27.906976744186, Blast_Score=121, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136446, Length=329, Percent_Identity=30.6990881458967, Blast_Score=112, Evalue=2e-24,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_DESDA (B8J1A8)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480213.1
- GeneID:   7285339
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1636
- HOGENOM:   HBG285547
- ProtClustDB:   PRK00405
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 154132; Mature: 154001

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQLTKQFGKIKISLPIPHLLNLQIDSYEKFLQEGVPEAERRPDEGLEGVFHTVFPIEDF
CCCCHHHHCCEEEEECCCCEEECEEHHHHHHHHCCCCHHHCCCCCHHHHHHHHHCCHHHC
NKTASLEFVSYEIGEPKYDQAECISKGLTYEAPMRIKVRLVVYDADEASGNRTIRDIKEQ
CCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHC
DIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDGGKTHTSRKVLYSCRVIPMR
CEEEEECCEEECCCCEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFDFDHKDILYVRIDRRRKMPATILFKAMGMSKEQILDYFYTQETYRLEERNTIFW
CCEEECCCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCHHEEECCCCCHHH
EVRKELYRKDNAYADIVDSEGNVIVKAGKPITKRSWRLICEAGIEAIEMRPDTLDGMFLA
HHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEE
GDVADPKTGELLAEAADEITPGLLDRMRDAGINRVSVLHTKGNDTSSSIRDTLMLDRIPD
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCH
QLKAQEEIYRRLRPSSPPTAEIAASFFDNLFRNPDYYDLSPVGRYKLNQRLSLDEPSDLR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCC
TLTDNDILTAIKVLVHLKDSHGPADDIDHLGNRRVRLVGELVENQYRIGLVRMERAIKER
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
MSLQEISTLMPHDLINPKPVAAVLKEFFGTSQLSQFMDQTNSLSEVTHKRRLSALGPGGL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
TRERAGFEVRDVHTSHYGRICPIETPEGPNIGLIVSLTTFAKVNDYGFIETPYHVVREGR
CHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHCCC
VTDEVLHLDASREGDQVVAQANALLDEQGNLVDEFVTVRVKGEVEMRHRDEVTLMDISPS
CCHHHHEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCEEEEECCHH
QMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSEKPLVGTGMEVDVARDSGACIVA
HHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCCCCCEECCCEEEEECCCCCEEEE
PADGKIEYVDADRIVVAYEGDVYKKQGGVRAYDLLKYHKSNQNSCFGQKPSCHPGQIVKK
CCCCEEEEEECCEEEEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC
GQILADGPGIDDGELALGKNLVVAFMPWCGYNYEDSILISERTVKEDVFTSIHIEEFEVV
CEEEECCCCCCCCCEECCCCEEEEEECCCCCCCCCCEEEECHHHHHHHHHEEEHHHHHHH
ARDTKLGPEEITRDIPNVSEDMLRNLDESGIIRIGAAVKPDDILVGKITPKGETQLTPEE
HHCCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHH
KLLRAIFGEKARDVKNTSLKVPPGVEGTIIDVKVFNRRSGEKDDRTLAIEGHDTAVLDQK
HHHHHHHCHHHHCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCEEECCH
EADHMRALTDRTRALLIPHVVGKQVAASLPGKKKGEVLVEAGAALTEEMLASLPVKKLSG
HHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCHHHHHH
LFKSKEVNDAVAEILKPYDQQVDYLHAIYDSKREKVTEGDDLPPGVIKMVKVHIAIKRKL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SVGDKMAGRHGNKGVVSCILPEEDMPFFADGRPVDIVLNPLGVPSRMNIGQIMETHLGWG
CCCCHHCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
AKELGRQLAELLDSGAAMQVLRDEVKSIFSSDDINALVDEMDDEEFKASVSKLRNGIVTK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCEEE
TPVFDGATEEEIWSWMERAGLANDGKTTLYDGRTGEAFKNRVTTGVMYMLKLHHLVDEKI
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVK
HCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHH
MYEKIVKGDNFLEAGLPESFNVLVKELMSLGLNVTLHQEEGKKKPKRTGYMREREDEA
HHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GQLTKQFGKIKISLPIPHLLNLQIDSYEKFLQEGVPEAERRPDEGLEGVFHTVFPIEDF
CCCHHHHCCEEEEECCCCEEECEEHHHHHHHHCCCCHHHCCCCCHHHHHHHHHCCHHHC
NKTASLEFVSYEIGEPKYDQAECISKGLTYEAPMRIKVRLVVYDADEASGNRTIRDIKEQ
CCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHC
DIYFGTLPLMTEKGTFIINGTERVIVNQLQRSPGIIFEHDGGKTHTSRKVLYSCRVIPMR
CEEEEECCEEECCCCEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFDFDHKDILYVRIDRRRKMPATILFKAMGMSKEQILDYFYTQETYRLEERNTIFW
CCEEECCCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCHHEEECCCCCHHH
EVRKELYRKDNAYADIVDSEGNVIVKAGKPITKRSWRLICEAGIEAIEMRPDTLDGMFLA
HHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEE
GDVADPKTGELLAEAADEITPGLLDRMRDAGINRVSVLHTKGNDTSSSIRDTLMLDRIPD
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCH
QLKAQEEIYRRLRPSSPPTAEIAASFFDNLFRNPDYYDLSPVGRYKLNQRLSLDEPSDLR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCC
TLTDNDILTAIKVLVHLKDSHGPADDIDHLGNRRVRLVGELVENQYRIGLVRMERAIKER
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
MSLQEISTLMPHDLINPKPVAAVLKEFFGTSQLSQFMDQTNSLSEVTHKRRLSALGPGGL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
TRERAGFEVRDVHTSHYGRICPIETPEGPNIGLIVSLTTFAKVNDYGFIETPYHVVREGR
CHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHCCC
VTDEVLHLDASREGDQVVAQANALLDEQGNLVDEFVTVRVKGEVEMRHRDEVTLMDISPS
CCHHHHEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCEEEEECCHH
QMVSISAALIPFLEHDDANRALMGSNMQRQAVPLLRSEKPLVGTGMEVDVARDSGACIVA
HHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCCCCCEECCCEEEEECCCCCEEEE
PADGKIEYVDADRIVVAYEGDVYKKQGGVRAYDLLKYHKSNQNSCFGQKPSCHPGQIVKK
CCCCEEEEEECCEEEEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC
GQILADGPGIDDGELALGKNLVVAFMPWCGYNYEDSILISERTVKEDVFTSIHIEEFEVV
CEEEECCCCCCCCCEECCCCEEEEEECCCCCCCCCCEEEECHHHHHHHHHEEEHHHHHHH
ARDTKLGPEEITRDIPNVSEDMLRNLDESGIIRIGAAVKPDDILVGKITPKGETQLTPEE
HHCCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHH
KLLRAIFGEKARDVKNTSLKVPPGVEGTIIDVKVFNRRSGEKDDRTLAIEGHDTAVLDQK
HHHHHHHCHHHHCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCEEECCH
EADHMRALTDRTRALLIPHVVGKQVAASLPGKKKGEVLVEAGAALTEEMLASLPVKKLSG
HHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCHHHHHH
LFKSKEVNDAVAEILKPYDQQVDYLHAIYDSKREKVTEGDDLPPGVIKMVKVHIAIKRKL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SVGDKMAGRHGNKGVVSCILPEEDMPFFADGRPVDIVLNPLGVPSRMNIGQIMETHLGWG
CCCCHHCCCCCCCCEEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
AKELGRQLAELLDSGAAMQVLRDEVKSIFSSDDINALVDEMDDEEFKASVSKLRNGIVTK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCEEE
TPVFDGATEEEIWSWMERAGLANDGKTTLYDGRTGEAFKNRVTTGVMYMLKLHHLVDEKI
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAAYLLQEFLTVKSDDVTGRVK
HCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHH
MYEKIVKGDNFLEAGLPESFNVLVKELMSLGLNVTLHQEEGKKKPKRTGYMREREDEA
HHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA